KR100829842B1 - Ｃｙｒ61 구성 및 방법 - Google Patents

Ｃｙｒ61 구성 및 방법 Download PDF

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KR100829842B1
KR100829842B1 KR1020027009831A KR20027009831A KR100829842B1 KR 100829842 B1 KR100829842 B1 KR 100829842B1 KR 1020027009831 A KR1020027009831 A KR 1020027009831A KR 20027009831 A KR20027009831 A KR 20027009831A KR 100829842 B1 KR100829842 B1 KR 100829842B1
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cyr61
cells
cell
human
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KR20020089336A (ko
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라우레스터에프
영조-아우
그린스팬제프리에이
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무닌 코포레이션
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Priority claimed from US09/495,448 external-priority patent/US6790606B1/en
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
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    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5032—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on intercellular interactions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
    • G—PHYSICS
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
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  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Gastroenterology & Hepatology (AREA)
KR1020027009831A 2000-01-31 2001-01-31 Ｃｙｒ61 구성 및 방법 Expired - Fee Related KR100829842B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US09/495,448 US6790606B1 (en) 1996-03-15 2000-01-31 Extracellular matrix signaling molecules
US09/495,448 2000-01-31
US20436400P 2000-05-15 2000-05-15
US60/204,364 2000-05-15
US23870500P 2000-10-06 2000-10-06
US60/238,705 2000-10-06

Publications (2)

Publication Number Publication Date
KR20020089336A KR20020089336A (ko) 2002-11-29
KR100829842B1 true KR100829842B1 (ko) 2008-05-16

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EP (1) EP1254174B1 (enExample)
JP (1) JP2003527109A (enExample)
KR (1) KR100829842B1 (enExample)
CN (1) CN1447819B (enExample)
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AU (2) AU2001234721B8 (enExample)
CA (1) CA2398660A1 (enExample)
DE (1) DE60128066T2 (enExample)
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EP1608970A4 (en) * 2003-03-31 2006-06-14 Munin Corp CCN3 COMPOSITIONS AND METHODS
JP2004315480A (ja) * 2003-04-21 2004-11-11 Yoshiyuki Kakehi 前立腺疾患治療用医薬組成物
TWI356097B (en) * 2003-06-20 2012-01-11 Munin Corp Ccn1 compositions and methods
US20050177885A1 (en) * 2004-02-09 2005-08-11 Lau Lester F. CCN1 transgenic animals
WO2006069198A1 (en) 2004-12-22 2006-06-29 Cleveland Clinic Foundation Flagellin related polypeptides and uses thereof
JP5153324B2 (ja) 2005-03-14 2013-02-27 生化学工業株式会社 硬組織形成促進剤
US20100034892A1 (en) 2006-08-30 2010-02-11 The Trustees Of Columbia University In The City Of New York Treatment for bone formation disorders by growth factor delivery
US8188220B2 (en) * 2006-12-06 2012-05-29 Sanford-Burnham Medical Research Institute Methods and compositions related to targeting wounds, regenerating tissue, and tumors
ES2412237T3 (es) 2008-08-01 2013-07-10 Cleveland Biolabs, Inc. Métodos para tratar lesiones por reperfusión
CN101747435B (zh) * 2008-12-18 2013-06-19 上海市免疫学研究所 一种中和cyr61的单克隆抗体(杂交瘤)及其应用
TW201102086A (en) 2009-06-04 2011-01-16 Hoffmann La Roche Antibodies against human CCN1 and uses thereof
KR101187814B1 (ko) * 2010-03-22 2012-10-08 광주과학기술원 심부전 예방 또는 치료용 약제학적 조성물 및 심부전 예방 또는 치료제의 스크리닝 방법
SG191830A1 (en) 2011-01-10 2013-08-30 Cleveland Biolabs Inc Use of toll-like receptor agonist for treating cancer
ES2816630T3 (es) 2014-07-30 2021-04-05 Genome Prot Inc Composiciones de flagelina y usos
US10183056B2 (en) 2014-10-16 2019-01-22 Cleveland Biolabs, Inc. Methods and compositions for the treatment of radiation-related disorders
CN108840920B (zh) * 2018-06-19 2021-09-28 中山大学孙逸仙纪念医院 一种人CYR61蛋白Ser167位点磷酸化抗原、抗体及其制备方法和应用
CN111939272B (zh) * 2020-08-21 2023-02-24 上海交通大学医学院附属第九人民医院 Ccn1的用途
CN115058388A (zh) * 2022-03-14 2022-09-16 福建医科大学附属协和医院 间充质干细胞创面修复优势功能亚群及其鉴定和应用

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Non-Patent Citations (1)

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Title
PNAS, USA, Vol. 95, May 1998, p 6355-6360

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EP1254174A2 (en) 2002-11-06
AU2001234721B8 (en) 2006-07-27
WO2001055210A3 (en) 2002-05-02
IL150885A0 (en) 2003-02-12
CA2398660A1 (en) 2001-08-02
IL195337A0 (en) 2009-08-03
DE60128066T2 (de) 2007-12-27
AU2001234721B2 (en) 2006-03-30
IL150885A (en) 2012-07-31
ATE360643T1 (de) 2007-05-15
JP2003527109A (ja) 2003-09-16
WO2001055210A2 (en) 2001-08-02
EP1254174B1 (en) 2007-04-25
HK1047945A1 (en) 2003-03-14
DE60128066D1 (de) 2007-06-06
KR20020089336A (ko) 2002-11-29
CN1447819B (zh) 2011-06-22
AU3472101A (en) 2001-08-07
HK1047945B (en) 2007-12-28
CN1447819A (zh) 2003-10-08

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