KR100805771B1 - 면역조절을 위한 허피스 바이러스 - Google Patents

면역조절을 위한 허피스 바이러스 Download PDF

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KR100805771B1
KR100805771B1 KR1020027013753A KR20027013753A KR100805771B1 KR 100805771 B1 KR100805771 B1 KR 100805771B1 KR 1020027013753 A KR1020027013753 A KR 1020027013753A KR 20027013753 A KR20027013753 A KR 20027013753A KR 100805771 B1 KR100805771 B1 KR 100805771B1
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virus
gene
herpes virus
attenuated herpes
functional
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Korean (ko)
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KR20030047883A (ko
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코핀로버트스튜어트
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바이오벡스 리미티드
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/763—Herpes virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/19—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24—Antigen-presenting cells [APC]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16632—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16641—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
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  • Wood Science & Technology (AREA)
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  • Molecular Biology (AREA)
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  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020027013753A 2000-04-12 2001-04-12 면역조절을 위한 허피스 바이러스 Expired - Fee Related KR100805771B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0009079.5 2000-04-12
GBGB0009079.5A GB0009079D0 (en) 2000-04-12 2000-04-12 Herpes viruses for immune modulation
PCT/GB2001/001666 WO2001077358A2 (en) 2000-04-12 2001-04-12 Herpes viruses for immune modulation

Publications (2)

Publication Number Publication Date
KR20030047883A KR20030047883A (ko) 2003-06-18
KR100805771B1 true KR100805771B1 (ko) 2008-02-21

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KR1020027013753A Expired - Fee Related KR100805771B1 (ko) 2000-04-12 2001-04-12 면역조절을 위한 허피스 바이러스

Country Status (18)

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EP (1) EP1272652B1 (enExample)
JP (2) JP2003530369A (enExample)
KR (1) KR100805771B1 (enExample)
CN (1) CN100351385C (enExample)
AT (1) ATE278795T1 (enExample)
AU (1) AU783395B2 (enExample)
BR (1) BR0109928A (enExample)
CA (1) CA2405458C (enExample)
DE (1) DE60106222T2 (enExample)
DK (1) DK1272652T3 (enExample)
ES (1) ES2230291T3 (enExample)
GB (2) GB0009079D0 (enExample)
HK (1) HK1048136B (enExample)
IL (2) IL152055A0 (enExample)
MX (1) MXPA02010074A (enExample)
PT (1) PT1272652E (enExample)
WO (1) WO2001077358A2 (enExample)
ZA (1) ZA200207920B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7063851B2 (en) 2000-04-12 2006-06-20 Biovex Limited Herpes viruses for immune modulation
JP2004099584A (ja) * 2002-05-02 2004-04-02 Keio Gijuku Ｈｓｖを用いた抗腫瘍剤
US7695725B2 (en) * 2003-02-06 2010-04-13 Aduro Biotech Modified free-living microbes, vaccine compositions and methods of use thereof
GB0317511D0 (en) 2003-07-25 2003-08-27 Biovex Ltd Viral vectors
US7842289B2 (en) 2003-12-24 2010-11-30 Aduro Biotech Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof
WO2007016239A2 (en) * 2005-07-29 2007-02-08 President And Fellows Of Harvard College Herpes simplex virus mutant and uses therefore
CN102146418B (zh) * 2010-02-09 2014-01-15 武汉滨会生物科技有限公司 重组ⅱ型单纯疱疹病毒载体及其制备方法、重组病毒、药物组合物及应用
CN105219739A (zh) * 2015-09-21 2016-01-06 北京神源德生物科技有限公司 重组单纯疱疹病毒及它感染和制备它的宿主细胞以及它们的应用
CN105219738A (zh) * 2015-09-21 2016-01-06 北京神源德生物科技有限公司 重组单纯疱疹病毒及它感染和制备它的宿主细胞以及它们的应用
JP7075653B2 (ja) * 2018-02-06 2022-05-26 学校法人福岡大学 αヘルペスウイルス感染を処置する方法及び医薬組成物
CN109161561A (zh) * 2018-08-09 2019-01-08 湖北科技学院 一种选择性杀灭前列腺癌细胞的新型溶瘤病毒及其构建方法
KR20250024845A (ko) * 2022-08-05 2025-02-19 임비라 바이오파마수티컬스 컴퍼니 리미티드 복제 결함형 헤르페스 심플렉스 바이러스 1형바이러스 백신

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000008191A2 (en) * 1998-07-31 2000-02-17 Biovex Limited Herpes virus vectors for dendritic cells

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763217A (en) * 1993-11-10 1998-06-09 University Of British Columbia Method of using, process of preparing and composition comprising recombinant herpesvirus vectors
GB9615794D0 (en) * 1996-07-26 1996-09-04 Medical Res Council Mutant herpes simplex virus strains and uses thereof
US5998174A (en) * 1997-05-12 1999-12-07 University Of Pittsburgh Of The Commonwealth System Of Higher Education Multigene vectors
GB9801930D0 (en) * 1998-01-29 1998-03-25 Univ London Mutant herpes simplex viruses and uses thereof
GB9810904D0 (en) * 1998-05-20 1998-07-22 Univ London Mutant herpes simplex viruses and uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000008191A2 (en) * 1998-07-31 2000-02-17 Biovex Limited Herpes virus vectors for dendritic cells

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
국제공개공보 제0008191호

Also Published As

Publication number Publication date
ATE278795T1 (de) 2004-10-15
ES2230291T3 (es) 2005-05-01
DE60106222T2 (de) 2005-10-13
CA2405458C (en) 2011-08-30
EP1272652B1 (en) 2004-10-06
CN1439056A (zh) 2003-08-27
PT1272652E (pt) 2004-12-31
JP2003530369A (ja) 2003-10-14
BR0109928A (pt) 2003-05-27
MXPA02010074A (es) 2003-04-25
IL152055A0 (en) 2003-05-29
WO2001077358A2 (en) 2001-10-18
AU4672801A (en) 2001-10-23
CN100351385C (zh) 2007-11-28
DK1272652T3 (da) 2005-02-14
AU783395B2 (en) 2005-10-20
JP5543528B2 (ja) 2014-07-09
KR20030047883A (ko) 2003-06-18
GB0009079D0 (en) 2000-05-31
GB0224000D0 (en) 2002-11-20
HK1048136A1 (en) 2003-03-21
EP1272652A2 (en) 2003-01-08
IL152055A (en) 2010-12-30
GB2376687A (en) 2002-12-24
JP2012188440A (ja) 2012-10-04
ZA200207920B (en) 2004-07-08
CA2405458A1 (en) 2001-10-18
DE60106222D1 (de) 2004-11-11
GB2376687B (en) 2004-06-09
HK1048136B (zh) 2004-12-03
WO2001077358A3 (en) 2002-03-14

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