KR100685059B1 - 펜타플루오로벤젠술폰아미드를 사용하는 복합 치료법 - Google Patents

펜타플루오로벤젠술폰아미드를 사용하는 복합 치료법 Download PDF

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Publication number
KR100685059B1
KR100685059B1 KR1020027001254A KR20027001254A KR100685059B1 KR 100685059 B1 KR100685059 B1 KR 100685059B1 KR 1020027001254 A KR1020027001254 A KR 1020027001254A KR 20027001254 A KR20027001254 A KR 20027001254A KR 100685059 B1 KR100685059 B1 KR 100685059B1
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South Korea
Prior art keywords
compound
cisplatin
acid
pentafluorobenzenesulfonamide
alkyl
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Expired - Fee Related
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KR1020027001254A
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English (en)
Korean (ko)
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KR20020050225A (ko
Inventor
수잔 스웬드너
피터 팀머만
재키 월링
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암젠 인크
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Publication of KR20020050225A publication Critical patent/KR20020050225A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Weting (AREA)
KR1020027001254A 1999-07-29 2000-07-27 펜타플루오로벤젠술폰아미드를 사용하는 복합 치료법 Expired - Fee Related KR100685059B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14643699P 1999-07-29 1999-07-29
US60/146,436 1999-07-29

Publications (2)

Publication Number Publication Date
KR20020050225A KR20020050225A (ko) 2002-06-26
KR100685059B1 true KR100685059B1 (ko) 2007-02-22

Family

ID=22517356

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020027001254A Expired - Fee Related KR100685059B1 (ko) 1999-07-29 2000-07-27 펜타플루오로벤젠술폰아미드를 사용하는 복합 치료법

Country Status (16)

Country Link
US (1) US6355628B1 (https=)
EP (1) EP1206256B8 (https=)
JP (1) JP2003505513A (https=)
KR (1) KR100685059B1 (https=)
CN (1) CN1181819C (https=)
AT (1) ATE294574T1 (https=)
AU (1) AU775305B2 (https=)
CA (1) CA2380078C (https=)
DE (1) DE60019937T2 (https=)
DK (1) DK1206256T3 (https=)
ES (1) ES2241639T3 (https=)
IL (2) IL147890A0 (https=)
PT (1) PT1206256E (https=)
RU (1) RU2268054C2 (https=)
WO (1) WO2001008693A2 (https=)
ZA (1) ZA200200889B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69724777T2 (de) * 1996-02-22 2004-07-15 Tularik, Inc., South San Francisco Pentafluorobenzensulfonamiden und analoge
PT939627E (pt) * 1996-07-19 2004-02-27 Tularik Inc Pentafluorobenzenossulfonamidas e analogos
ES2194547T3 (es) * 1998-09-23 2003-11-16 Tularik Inc Arilsulfonanilida-ureas.
US20050250854A1 (en) * 2000-11-03 2005-11-10 Amgen Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
WO2002039958A2 (en) 2000-11-03 2002-05-23 Tularik Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
FR2834641B1 (fr) * 2002-01-14 2005-04-22 Ct Regional De Lutte Contre Le Protection de la neurotoxicite de l'oxaliplatine par administration de calcium et de magnesium
WO2005051303A2 (en) * 2003-11-19 2005-06-09 Lixin Zhang Screening for synergistic compounds
US10238831B2 (en) 2013-09-08 2019-03-26 Qool Therapeutics, Inc. Temperature measurement and feedback for therapeutic hypothermia
CN107530187B (zh) 2015-02-23 2020-06-30 库尔诊疗公司 用于冷冻颗粒的气管内递送的系统
EP3676255B1 (en) 2017-08-29 2025-04-16 Rutgers, The State University University Of New Jersey Therapeutic indazoles
EP3684754A4 (en) * 2017-09-21 2021-06-02 Dalriada Therapeutics Inc. PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND ASSOCIATED USES

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1955207A (en) 1931-09-16 1934-04-17 Ig Farbenindustrie Ag Mothproofing agent
US2402623A (en) 1943-06-24 1946-06-25 Rohm & Haas Nu-nitroaryl haloarylsulphonamides
CH362688A (de) 1957-09-10 1962-06-30 Geigy Ag J R Verfahren zur Herstellung von neuen Arylsulfonarylamiden
GB1242057A (en) 1968-07-04 1971-08-11 Ici Ltd Derivatives of 4-hydroxytetrafluoropyridine and the use thereof as plant growth regulators
NL174644C (nl) 1970-04-13 1984-07-16 Minnesota Mining & Mfg Werkwijze ter bereiding van een herbicide verbinding; tevens werkwijze voor de bereiding van een preparaat met herbicide werking.
SE447902B (sv) * 1977-10-19 1986-12-22 Johnson Matthey Co Ltd Cis-koordinationsforening av platina och komposition innehallande foreningen
DE3623184A1 (de) 1986-07-10 1988-01-14 Kali Chemie Ag Verfahren zur herstellung von n-fluorsulfonamiden
US4883914A (en) 1987-08-17 1989-11-28 American Cyanamid Company Benzenesulfonyl carboxamide compounds useful as herbicidal agents
DE3804990A1 (de) 1988-02-18 1989-08-31 Basf Ag Herbizid wirksame, heterocyclisch substituierte sulfonamide
FR2645537B1 (fr) 1989-04-05 1994-03-04 Fabre Medicament Pierre Nouveaux sulfonamides derives d'acides benzocycliques ou benzoheterocycliques, leur preparation et leur application en therapeutique
FR2665440B1 (fr) 1990-07-31 1994-02-04 Lipha Nouveaux cycloalkylsulfonamides substitues, procedes de preparation et medicaments les contenant.
US5189211A (en) 1990-08-01 1993-02-23 Taisho Pharmaceutical Co., Ltd. Sulfonamide derivatives
EP0472053B1 (en) 1990-08-20 1998-06-17 Eisai Co., Ltd. Sulfonamide derivatives
RU2088288C1 (ru) * 1993-07-29 1997-08-27 Московский областной научно-исследовательский клинический институт Способ лечения больных местнораспространенными формами рака
RU2098096C1 (ru) * 1993-10-11 1997-12-10 Московский научно-исследовательский онкологический институт им.П.А.Герцена Средства, подавляющие рост раковых клеток
WO1996040629A1 (en) 1995-06-07 1996-12-19 Sugen, Inc. Tyrphostin-like compounds for the treatment of cell proliferative disorders or cell differentiation disorders
DE69724777T2 (de) 1996-02-22 2004-07-15 Tularik, Inc., South San Francisco Pentafluorobenzensulfonamiden und analoge
PT939627E (pt) * 1996-07-19 2004-02-27 Tularik Inc Pentafluorobenzenossulfonamidas e analogos
CZ298022B6 (cs) * 1996-10-15 2007-05-30 G. D. Searle & Co. Použití inhibitoru cyklooxygenázy-2 pro výrobu léciva pro lécení a prevenci neoplazie
JP2001505564A (ja) * 1996-11-19 2001-04-24 ジー．ディー．サール アンド カンパニー 抗血管新生剤としてのシクロオキシゲナーゼ―２阻害剤の使用方法
US5773236A (en) 1997-04-25 1998-06-30 Molecule Probes, Inc. Assay for glutathiane transferase using polyhaloaryl-substituted reporter molecules
ATE248845T1 (de) * 1998-06-25 2003-09-15 Tularik Inc Arylsulfonanilid-phosphate
ES2194547T3 (es) * 1998-09-23 2003-11-16 Tularik Inc Arilsulfonanilida-ureas.
AU2190700A (en) * 1998-12-17 2000-07-03 Tularik Inc. Tubulin-binding agents
CO5170498A1 (es) * 1999-05-28 2002-06-27 Abbott Lab Biaril sulfonamidas son utiles como inhibidores de proliferacion celular

Also Published As

Publication number Publication date
CA2380078C (en) 2008-05-06
EP1206256B1 (en) 2005-05-04
EP1206256B8 (en) 2005-06-29
WO2001008693A3 (en) 2001-05-25
ZA200200889B (en) 2003-03-26
US6355628B1 (en) 2002-03-12
KR20020050225A (ko) 2002-06-26
DK1206256T3 (da) 2005-08-15
ES2241639T3 (es) 2005-11-01
CA2380078A1 (en) 2001-02-08
CN1181819C (zh) 2004-12-29
AU6615200A (en) 2001-02-19
PT1206256E (pt) 2005-09-30
EP1206256A2 (en) 2002-05-22
AU775305B2 (en) 2004-07-29
RU2002105374A (ru) 2004-01-10
JP2003505513A (ja) 2003-02-12
CN1367690A (zh) 2002-09-04
IL147890A (en) 2007-07-04
WO2001008693A2 (en) 2001-02-08
RU2268054C2 (ru) 2006-01-20
DE60019937T2 (de) 2006-05-04
IL147890A0 (en) 2002-08-14
ATE294574T1 (de) 2005-05-15
DE60019937D1 (de) 2005-06-09

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