KR100634289B1 - Supplemantary Material and Manufacturing Method of the Same for Improving Physical Constitution of Atopy Dermatitis Patients - Google Patents

Abstract

The present invention relates to an adjuvant for improving and strengthening the constitution of atopic dermatitis patients to help the healing, in particular, to the atopic dermatitis patients caused by health problems such as anorexia, severe unbalance, weakness constitution The present invention provides a therapeutic agent for atopic dermatitis and a method for producing the same to promote atopic dermatitis by naturally improving the condition and restoring health and improving the development state.

Atopic Dermatitis Treatment Aids

Description

Atopy Dermatitis Treatment Aids and Manufacturing Method {Supplemantary Material and Manufacturing Method of the Same for Improving Physical Constitution of Atopy Dermatitis Patients}

The present invention relates to an adjuvant for improving and strengthening the constitution of atopic dermatitis patients to help the healing, in particular, to the atopic dermatitis patients caused by health problems such as anorexia, severe unbalance, weakness constitution The present invention provides a therapeutic agent for atopic dermatitis and a method for producing the same to promote atopic dermatitis by naturally improving the condition and restoring health and improving the development state.

Atopy, originally meant as 'weird' or 'inappropriate', is medically named for innate hypersensitivity to certain types of substances that are unique to humans. it means. The symptoms of atopic dermatitis, fever, asthma, and atopic dermatitis are often shown as a family history.It has a high positive rate of intradermal response to various allergens (eg, egg white, pollen, dust, etc.) and serum antibodies (atopic allergens). There is also an abnormal response to various stresses (temperature, humidity, mental strain, infection, etc.).

Among the symptoms of atopic dermatitis, atopic dermatitis is also called `` tape fever '', and itching in people with atopic dermatitis is very dry, eczema, etc. The cause is not well known, but there are many genetic factors and is associated with immune system deficiency. It is known that there is. The cause is known to be caused by a combination of dry skin, skin itch characteristics, infections caused by bacteria, viruses, fungi, emotional factors, environmental factors, etc. compared to normal people.

However, recent studies have shown that environmental pollution not only makes the genetic potential predisposition of atopic dermatitis more potent, but also causes atopic dermatitis in people without genetic predisposition. As described above, atopic dermatitis is a hypersensitivity reaction of the immune system to changes in the environment such as food, climate, and the conversion of specific substances.Atopic dermatitis is more common in people without genetic predisposition because environmental pollution destroys the human immune system. I'm doing it.

The atopic dermatitis is a skin disease that can be commonly seen around us, and 5 to 10% of children suffer from this, and many of them are known to suffer from atopic dermatitis even in adults.

However, most of the atopic dermatitis is caused by the immune system hypersensitivity to a particular food, which causes the atopic dermatitis patients to habitualize their eating habits, resulting in poor appetite and poor diet. There was a problem that even if you use a medicine or herbal medicine is not absorbed properly by the human body, so many difficulties in treatment.

In addition, atopic dermatitis has been known as a disease in which modern medicine does not have a fundamental treatment method, but rather has to control the symptoms through proper treatment and avoid the cause factor rather than aiming at cure.

Specifically, as a treatment method using both drugs for atopic dermatitis, nonsteroidal agents such as steroids, antihistamines, antibiotics, and moisturizers are used to treat itching and dermatitis as symptomatic therapy.

The corticosteroid is an adrenal cortex hormone and has an anti-inflammatory and immunosuppressive effect and is excellent in effect, but when used for a long time, the skin at the site of use may be hairy, the skin may shrink, skin pigment may be reduced, and bacterial infection may occur. And, there was a problem that serious side effects such as acne sprouting, skin thinning, blood vessels are exposed.

In addition, antihistamines are used as a temporary measure to alleviate the symptoms of itching by preventing histamine from being released from mast cells, and may cause side effects such as insomnia, dizziness, and loss of appetite when taken for a long time.

In addition, antibiotics are used to treat secondary bacterial infections such as staphylococci, which occur on scratched and scratched areas, and are not a fundamental treatment for atopic dermatitis itself.

In addition, in order to avoid the side effects of medicinal herbs, such as herbal medicine has recently been used. The herbal treatments are mainly a combination of herbal acupuncture or herbal medicine while applying an external herbal ointment, the taking medicine is cheongheumhaedoktang for bogeumboje for infants, Shihogagolgolmotang, dashho-tang, Soshiho-tang in adults, etc. . These herbal remedies are not just the main remedy to alleviate external symptoms but rather the healing of the underlying causes, and they are not a fundamental remedy.In addition, they are usually divided into pouches and packaged with water or hot water. Excipients for making dough are added to extracts made of hot water to make pills or granules.

However, the method of packaging and providing in the form of a pouch has a problem in that it is inconvenient to carry and take, and when the pills or granules are added to the excipient, the amount of the medicine is increased by the excipient and the patient takes unnecessary materials. There is a problem that the burden on the digestion of medicines, the economic cost of the unit price, packaging, transportation, etc. are added to the patient. In addition, the patients were not only aware that the pills or granules were all made with the necessary medicines for treatment, but did not know that unnecessary excipients were included in the treatment.

In order to solve the above-mentioned problems, the present invention does not affect the immune system of atopic dermatitis patients, and unlike the conventional or symptomatic treatments of both or oriental medicines, atopic dermatitis is mainly weak in the body and has immunity. By paying attention to the fact that the disease occurs and persists in these weak people, according to the new prescription, it provides constitutional supplements using a number of herbal medicines to improve the constitution by solving the health problems such as anorexia, severe unbalance, and weak constitution in patients with atopic dermatitis. It aims to naturally heal atopic dermatitis by strengthening it.

In addition, the present invention is to separate the herbal medicine that may take the raw material itself in terms of digestion or medicinal effects among the plurality of herbal medicines and the herbal medicine that can be taken directly by separating the herbal medicine that is difficult or undesirable to take the raw material itself is formed into a powder For herbal medicines that are difficult or undesirable to take directly, it is easy to carry and take by preparing sugar extract by mixing sugar and extract, and then preparing pills or granules by mixing powder and extract, and do not add unnecessary excipients for treatment in small amount. Another object is to be able to take one dose of granules or pills.

In order to achieve the above object, the present invention is used for symptoms such as blood fever, heat of the heart and phlegm, heat resistance, dry throat, thirst, thirst and heart with a hematopoietic tonic action; It is effective in nourishing tonic, and is used in oil well, mongsul, lobster, low back pain, diarrhea; Cornus milk used for headache, tinnitus, seawater disease, fever, excessive menstruation, etc. due to its effects such as stiffness, sinjeong, sensation reinforcement and convergence; Baek Bok-Ryeong, which is used to protect the spleen, sputum, and to stabilize the mind by acting on menopause, parenteral, heart, nerve, and bladder; Neck skin used to control acupuncture points and to control infinite osteoporosis and blood schizophrenia; Taxa used for jonggal, dehumidification, canning, and restriction; Schisandra chinensis, used to support gegal, sea water, waterways, and shortage of gold and water; Signs used to enhance appetite, to smooth out pain, and to relieve pain; Adjuvant for atopic dermatitis, which is used to soothe the dermis and is used to harmonize the rain, dermis and tiredness, dry cough, helplessness, loss of appetite, veins, and a royal dermatitis that controls the five phases. To provide.

In addition, after the preparation of the amount of the herbal medicine to take the step of separating the herbal medicine and extract to be taken directly into the herbal medicine to extract; Preparing a powder of herbal medicine to be taken directly among the separated herbal medicines; Extracting the extract from the isolated herbal medicines by extracting the extract with Sujeontang; Mixing and kneading the prepared powder and extract; It provides a method for producing an atopic dermatitis treatment aid comprising the step of making the kneaded herbal medicines into pills or granules.

Hereinafter, the present invention will be described in detail with reference to Examples.

According to the present invention, the herbal medicine used as an embodiment for preparing an adjuvant for improving and strengthening the constitution of patients with atopic dermatitis may be used as Sukjihwang, mature medicine, cornus, Baekbokryeong, Mokdanpi, Taxa, Schisandra chinensis, Sinus, dermis. , Yellow, and the like. And it may be used to further mix at least one of the ripe, ginseng, baekryeok, processed rich, mammundong or hides.

Sukjihwang is the main herbal medicine of Samul-tang (四 物 湯) is a major herbal medicine of various chronic diseases to fight the fever that appears due to the weak body, hematopoietic to strengthen the blood and blood vessels of the heart and phlegm, heat resistance (인), throat drying (건) Used for symptoms such as thirst.

In addition, mountain drugs are mountain roots of plants belonging to the family of asters, and are collected between the winter solstice and the winter solstice. The outer surface is white or yellowish brown, and the inside is powdered. It is hard to make keratin or gelatinized keratin, and its ingredients contain starch, mucus, protein, fat, arginine choline and diastases. · Kidney [腎臟] · Stomach · Liver meridians (經絡) acts, nourishing tonic (유), oil well, mongsul (夢 泄), crayfish low back pain, diarrhea.

In addition, Sansuyu (山茱萸) has the effect of strong sound (신), Sinjeong (신 精) and Shingi (腎氣) reinforcement, convergence. It is used for headache, tinnitus, seawater disease, fever and excessive menstruation. It is also used for folk remedies such as cold sweat and nocturnal enuresis. Tea and liquor is also blessed, the cold and cold (보), such as the effect (효과) is effective.

In addition, Baekbokryeong acts on menopause, parenteral, heart, nerve, and bladder to protect the spleen, sputum, and stabilize the mind. The results of pharmacological experiments have been shown to act as a diuretic, lowering blood sugar, sedation, etc., and is also known as an immune resurrection. It is also used for swelling of the spleen and swelling, and it is known to have excellent effects on diseases such as stomach, liver, interest, and kidneys. It is used as a herbal medicine for the treatment of patients.

In addition, Mokpipi (牧 丹皮) is the root of peony flowers governs acupuncture points, it is used for infinite osteoporosis (汗 骨蒸 혈) and blood division (血 分 熱).

Taxa is also used to govern jonggal, dehumidification, canning, and restriction.

In addition, Schisandra chinensis (五味子) is used to help Jigal, seawater and erosion, to control the lack of gold and water.

In addition, the cause of death is prescribed to increase appetite, pain relief, calming, pain, the dermis is used to clean the pores and to harmonize the rain.

In addition, Hwangjeong is a root of perennial herb of the family Liliaceae, and it is known as a round root, and it is effective in healing fatigue, thirst, dry cough, helplessness, loss of appetite, and vein, and to control Orochilsang. .

In addition, the ripe people have a good temper, they are used to control vomiting, and are used in the body, ripening, oil well, and urination. The processed rich are processed by the rich, which is a kind of extreme medicine, and are not used alone. Used for pain relief and diuretics. Macmundong is also used as an anti-inflammatory, tonic, antitussive, expectorant, and cardiac agent.

In addition, baekchul is a diuretic, sweating action against the dysfunction of water metabolism in the subcutaneous tissue, it is used for pain, gastroenteritis, edema, etc .; In addition, the dermis is used to soften joints and skin, control the water supply, remove clogs, and eliminate longitudinal pain.

In addition, ginseng restores and strengthens long-term functions, such as odor, stabilizes the mind, stops vigilance, brightens the eyes, makes the head wise and extends life if taken for a long time.

The blending ratio of the herbal medicines as described above is 10 ~ 40g of Sookji Hwang, 5 ~ 20g each of powdered acidic and cornus oil, taeksa, velvet skin, 5 ~ 15g each of Baekbokryeong, Schisandra chinensis, dermis each It consists of 3-10 g and 5-25 g of yellow sulfur.

At this time, the most suitable embodiment is composed by combining 30g of sulfur sujiji, 15g each of acid and corn coriander, taeksa, charcoal bark, 12g each of Baekbokryeong, Schisandra chinensis, sine, dermis 8g, 15g yellow.

In addition, according to the constitution and symptoms of atopic dermatitis patients in the range of ripe 1 ~ 3g, ginseng 0.5 ~ 25g, baekrye 3 ~ 10g, processed rich 0.5 ~ 2.0g, Macmundong 5 ~ 15g, dermis 3 ~ 10g It can be prepared by adding any one or more.

Next, it is easy to take the formulated herbal medicines directly, such as herbal medicines, Chinese corn, bokbokryeong, Schisandra chinensis, Caesar, dermis, Hwangjeong or medicinal herb added to it, processed rich and; It is categorized as Sugijihwang, Taxa, Bark skin or additional herbal medicines such as Baekchul, Macmundong, and Euphoria.

Next, the classified herbal medicines are prepared by extracting sugar from the medicinal herbs to prepare atopic dermatitis supplements, or added with the medicines, cornus, baekbokyeong, schisandra chinensis, schizophrenia, dermis or citrine which can be directly taken from the classified herbal medicines. Ikjiin, ginseng and processed rich herbal medicines are processed into a powder form using a mixer or millstone, and it is difficult to take Sukjihwang, Taxa, Bark skin, and additional herbal medicines such as Baekchul, Macmundong, and Yuchi. After preparing an extract, the powder and the extract are mixed and kneaded, prepared according to a desired form of pills or granules of a size suitable for eating, and then dried to prepare an atopic dermatitis treatment aid.

Atopic dermatitis treatment adjuvant of the present invention prepared as described above is to strengthen the user's kidney, strengthen the lungs, protect the gods, strengthen the stomach, enhance the appetite, harmonize the spleen, rain, stomach, It can help soften joints and skin, eliminate blemishes, and eliminate cramps.

In addition, as described above, by strengthening the functions of the renal water and the lungs, endocrine function is enhanced, hormone secretion is smoothly performed, blood circulation, metabolism, protein assimilation and fat accumulation, moisture accumulation, and warming effect It not only improves appetite and promotes development, but also naturally improves constitution and skin function, which is very effective in treating atopic dermatitis.

In fact, the constitution improver of the present invention prepared as described above can be observed that when taken for 15 to 30 days each of children and adults, itching first begins to disappear and atopic dermatitis symptoms begin to improve and heal.

Next, the atopic dermatitis treatment aid prepared by the present invention was administered to patients with atopic dermatitis, and the symptoms were shown as shown in [Table 1].

TABLE 1

division gender age Hospital treatment experience Inflammation site and extent Duration of taking Dosing result Patient A female 8 years old Yu (7-8 months) Systemic (severe, severe) 30 days Almost complete Patient B south 21 months radish Systemic (severe, severe) 1 month Cured Patient C south 12 years old radish Systemic (severe, moderate) 13th Cured Patient D south 8 years old U Systemic (severe, severe) 1 month Cured Patient E female 8 years old radish Systemic (severe, severe) 1 month Cured Patient F south 6 years old (About 5 years) Instep, buttocks, back (severe, severe) 1 month Symptom relief Patient G south 27 months radish Systemic (severe, severe) 10 days Symptom relief Patient H south 3 years old U Systemic (severe, severe) 1 month Symptom relief Patient I female 9 years old radish Joint, head, shoulder (severe, severe) 50 days Cured Patient J south 17 years old radish Systemic (severe, moderate) 20 days Cured Patient K south 15 years old radish Systemic (severe, severe) 1 month Cured Patient L female 9 years old radish Limb joints (severe, severe) 30 days Symptom relief Patient M female 10 years old radish Posterior joint (severe, severe) 1 month Almost complete Patient N south 11 years old radish Systemic (severe, severe) 30 days Almost complete Patient O female 7 years old radish Systemic (severe, severe) 40 days Almost complete Patient P south 7 years old radish Systemic (severe, severe) 1 month Symptom relief Patient Q female 8 years old radish Systemic (severe, severe) 1 month Symptom relief Patient R female 15 years old radish Systemic (severe, moderate) 20 days Cured Patient S south 10 years old radish Joint area (severe, moderate) 1 month Almost complete Patient T south 8 years old radish Systemic (severe, severe) 13th Symptom relief Patient U south 11 years old radish Systemic (severe, severe) 1 month Symptom relief Patient V female 5 years old radish Systemic (severe, severe) 30 days no effect Patient W south 2 years old radish Facial, joints, buttocks (severe, severe) 60 days no effect Patient X south 1 year old radish Systemic (severe, severe) 2 months no effect Patient Y south 9 years old radish Systemic (severe, severe) 1 month no effect

In [Table 1], 25 patients including males and females were included. The age group was not particularly limited, but mainly children under 10 years of age except a few adults or adolescents. Most of the symptoms were severe skin dryness and severe patients including inflammation, eczema and itching. The duration of supplements was about 10 to 50 days depending on symptoms.

In addition, the adjuvant according to the present invention used in the above embodiment was mixed with 30g of sucrose sulfur, caustic and cornus oil, 15g, talc, charcoal skin, 12g each of Baekbokryeong, sage, 8g of dermis and 15g of yellow sugar on a daily basis. In some cases, 1 ~ 3g, ginseng 0.5 ~ 25g, white ginseng 3 ~ 10g, processed rich 0.5 ~ 2.0g, Macmundong 5 ~ 15g, dermis 3 according to the patient's constitution and symptoms Any one or more were added and used within the range of ˜10 g.

In addition, the prepared adjuvant was to be taken to the patient three times a day, and the time of day was taken after breakfast, lunch and dinner.

As can be seen from the results of symptom improvement in [Table 1], some patients did not observe the improvement effect of taking the adjuvant according to the present invention. In some cases, most patients who showed efficacy improved or healed the symptoms such as skin inflammation and pruritus (itching) in more than 50% of patients despite the short period of time. In addition, the other 30% or more of the patients showed significant improvement. In particular, the symptom was cured despite the fact that the majority of patients with symptomatic cure had systemic inflammation in the short term of about 30 days or less. In addition, the symptom-improving effect of the patients appeared immediately at the end of the administration period after the start of the adjuvant, or long after about 8 months after the administration period.

As described above, the atopic dermatitis treatment aid prepared by the present invention fundamentally changes and strengthens the fragile constitution of the patient, thereby improving the natural healing power of atopic dermatitis, especially in patients with systemic inflammation for a short period of time. Despite taking it, the effect is greatly improved or cured.

In addition, the use of external preparations in conjunction with the adjuvant may further improve the healing effect.

In addition, in the manufacture of pills or granules, no excipients for solidification are used, which prevents the patient from taking unnecessary materials, and can produce a sufficient effect even in a small amount when taking a quantitative dose. Can be significantly reduced.

In addition, the hypersensitivity to the patient's food is alleviated by taking the adjuvant, and thus, the patient no longer has an unbalanced diet, thereby consuming nutrients from various foods evenly.

Claims (7)

As an atopic dermatitis treatment aid, Azo dermatitis treatment adjuvant comprising a combination of Sukjihwang, mountain medicine, cornus, Paekbokyeong, Mokdanpi, Taxa, Schisandra chinensis, Caesar, Dermis, Yellow Jung. The method of claim 1, The atopic dermatitis treatment adjuvant is 10 ~ 40g Hwangji Hwangji, 5 ~ 20g each of acid and lactation, Taxa, neck skin, 5 ~ 15g each of Baekbokyeong, Schisandra, sine, dermis 3 ~ 10g, yellow 5-25g Atopic dermatitis treatment aid, characterized in that consisting of. The method of claim 1, The treatment aid is atopic dermatitis treatment aid, characterized in that prepared in pill or granules. The method of claim 1, Atopy dermatitis treatment aid, characterized in that it further comprises at least one of ripe, white, ginseng, processed rich, mammundong, dermis in the treatment aid. The method of claim 4, wherein The mixed amount of the herbal medicine is atopic dermatitis, characterized in that the raw 1 ~ 3g, Baekchul 3 ~ 10g, ginseng 0.5 ~ 25g, processed rich 0.5 ~ 2.0g, Macmundong 5 ~ 15g, dermal 3 ~ 10g based on the daily basis Treatment aids. In order to manufacture the atopic dermatitis treatment aid of claim 1, Screening suukjihwang, medicinal herb, cornus milk, baekbokyeong, bark skin, taxa, Schizandra chinensis, coriander, dermis, yellowing; Classifying the selected herbal medicines directly into herbal medicines that can be directly taken and difficult to take directly; Pulverizing the herbal medicines that can be directly taken from the selected herbal medicines to produce a powder; Preparing an extract by tapping a herbal medicine that is difficult to take directly from the selected herbal medicines; Mixing and kneading the prepared powder and extract; Forming the kneaded herbal medicines into a pill or granules, and then drying the method for producing atopic dermatitis treatment aids comprising the step of drying. The method of claim 6, In the step of combining the herbal medicines, A method of producing atopic dermatitis treatment aid further comprising the step of further blending at least one of ripe, baekchul, ginseng, processed rich, macmundong, dermis.