KR100602857B1 - 감각 정보 전달과 관련된 ｇ-단백질 커플링된 수용체를암호화하는 핵산 - Google Patents

감각 정보 전달과 관련된 ｇ-단백질 커플링된 수용체를암호화하는 핵산 Download PDF

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KR100602857B1
KR100602857B1 KR1020017001140A KR20017001140A KR100602857B1 KR 100602857 B1 KR100602857 B1 KR 100602857B1 KR 1020017001140 A KR1020017001140 A KR 1020017001140A KR 20017001140 A KR20017001140 A KR 20017001140A KR 100602857 B1 KR100602857 B1 KR 100602857B1
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gpcr
seq
leu
receptor
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KR20010085306A (ko
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쥬커찰스에스
애들러존엘리엇
린데마이어쥬에르겐
리바닉
훈마크
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더 리전트 오브 더 유니버시티 오브 캘리포니아
더 가번먼트 오브 더 유나이티드 스테이츠 오브 아메리카 레프리젠티드 바이 더 세크러터리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비시즈
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
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  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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KR1020017001140A 1998-07-28 1999-07-27 감각 정보 전달과 관련된 ｇ-단백질 커플링된 수용체를암호화하는 핵산 Expired - Fee Related KR100602857B1 (ko)

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US9446598P 1998-07-28 1998-07-28
US60/094,465 1998-07-28

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KR20010085306A KR20010085306A (ko) 2001-09-07
KR100602857B1 true KR100602857B1 (ko) 2006-07-20

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US (3) US20030036630A1 (enExample)
EP (1) EP1100810A4 (enExample)
JP (2) JP2002521049A (enExample)
KR (1) KR100602857B1 (enExample)
CN (1) CN1198836C (enExample)
AU (1) AU753703B2 (enExample)
BR (1) BR9912545A (enExample)
CA (2) CA2335318C (enExample)
IL (2) IL140979A0 (enExample)
NO (1) NO20010363L (enExample)
WO (1) WO2000006592A1 (enExample)
ZA (1) ZA200100401B (enExample)

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US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
AU2976000A (en) * 1999-01-27 2000-08-18 Regents Of The University Of California, The Assays for sensory modulators using a sensory cell specific g-pr otein beta subunit
US6929925B1 (en) 1999-01-27 2005-08-16 The Regents Of The University Of California Assays for sensory modulators using a sensory cell specific G-protein beta subunit
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
ATE366261T1 (de) * 2000-03-28 2007-07-15 Lexicon Genetics Inc Humane 7-transmembranproteine und dafür codierende polynukleotide
EP1301595A2 (en) * 2000-05-22 2003-04-16 Incyte Genomics, Inc. G-protein coupled receptors
AU2001266975A1 (en) * 2000-06-16 2002-01-02 Incyte Genomics, Inc. G-protein coupled receptors
CA2424821A1 (en) * 2000-10-10 2002-04-18 Pe Corporation (Ny) Gene encoding a human g-protein coupled receptor and its use
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7301009B2 (en) 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US7309577B2 (en) 2001-03-07 2007-12-18 Senomyx, Inc. Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste
US20080244761A1 (en) 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US7763431B1 (en) 2001-03-07 2010-07-27 Senomyx, Inc. Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste
WO2002086079A2 (en) * 2001-04-20 2002-10-31 Mount Sinai School Of Medicine T1r3 a novel taste receptor
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
EP2327985B2 (en) 2001-06-26 2019-08-21 Senomyx, Inc. T1R Hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
DK2327985T3 (en) 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
JP5001512B2 (ja) * 2001-06-26 2012-08-15 セノミックス インコーポレイテッド Ｔ１ｒヘテロオリゴマー味覚受容体及び前記受容体を発現する細胞系並びに味覚化合物の特定のためのその使用
WO2003025137A2 (en) * 2001-09-18 2003-03-27 Irm, Llc Sweet taste receptors
AU2004256023B2 (en) 2003-06-27 2008-03-13 Monell Chemical Senses Center Taste receptors of the T1R family from domestic cat
NZ619746A (en) 2003-08-06 2014-05-30 Senomyx Inc Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof
US8796441B2 (en) 2005-04-13 2014-08-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Human sweet and umami taste receptor variants
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US20110097741A1 (en) * 2006-04-20 2011-04-28 Jay Patrick Slack Partial t1r2 nucleic acid sequence, receptor protein and its use in screening assays
US8148536B2 (en) 2006-04-21 2012-04-03 Senomyx, Inc. Comestible compositions comprising high potency savory flavorants, and processes for producing them
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
WO2013022948A1 (en) 2011-08-08 2013-02-14 The Coca-Cola Company Cell lines comprising endogenous taste receptors and their uses
US9804157B1 (en) 2013-03-15 2017-10-31 Senomyx, Inc. Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives
WO2021150686A1 (en) 2020-01-22 2021-07-29 Firmenich Incorporated High-sensitivity detection of gpcr activity and uses thereof

Family Cites Families (4)

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Publication number Priority date Publication date Assignee Title
US4146501A (en) * 1975-12-12 1979-03-27 Henkin Robert I Process for isolating and purifying taste bud receptors for screening and evaluating tastants
US5688662A (en) * 1992-04-09 1997-11-18 Linguagen Corporation Gustducin polynucleotides, vectors, host cells and recombinant methods
US7368285B2 (en) * 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
KR101511394B1 (ko) * 2007-01-18 2015-04-10 지보당 에스아 키메라 우마미 미각 수용체, 이를 코딩하는 핵산 및 이의 용도

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CA2335318A1 (en) 2000-02-10
NO20010363D0 (no) 2001-01-22
WO2000006592A1 (en) 2000-02-10
ZA200100401B (en) 2001-10-31
CA2776054A1 (en) 2000-02-10
JP2002521049A (ja) 2002-07-16
CA2776054C (en) 2016-08-30
AU5238199A (en) 2000-02-21
WO2000006592A9 (en) 2000-11-02
BR9912545A (pt) 2001-10-30
JP2009261399A (ja) 2009-11-12
CN1317010A (zh) 2001-10-10
EP1100810A4 (en) 2002-09-18
CA2335318C (en) 2012-05-01
US20070185312A1 (en) 2007-08-09
IL140979A0 (en) 2002-02-10
EP1100810A1 (en) 2001-05-23
NO20010363L (no) 2001-03-26
US20030036630A1 (en) 2003-02-20
US20090148948A1 (en) 2009-06-11
CN1198836C (zh) 2005-04-27
KR20010085306A (ko) 2001-09-07
AU753703B2 (en) 2002-10-24
IL140979A (en) 2008-07-08

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