CA2335318C - Nucleic acids encoding a g-protein coupled receptor involved in sensory transduction - Google Patents
Nucleic acids encoding a g-protein coupled receptor involved in sensory transduction Download PDFInfo
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- CA2335318C CA2335318C CA2335318A CA2335318A CA2335318C CA 2335318 C CA2335318 C CA 2335318C CA 2335318 A CA2335318 A CA 2335318A CA 2335318 A CA2335318 A CA 2335318A CA 2335318 C CA2335318 C CA 2335318C
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- Proteomics, Peptides & Aminoacids (AREA)
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- Toxicology (AREA)
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- Cell Biology (AREA)
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- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2776054A CA2776054C (en) | 1998-07-28 | 1999-07-27 | Nucleic acids encoding a g-protein coupled receptor involved in sensory transduction |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US9446598P | 1998-07-28 | 1998-07-28 | |
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| US7402400B2 (en) | 2001-07-03 | 2008-07-22 | Regents Of The University Of California | Mammalian sweet taste receptors |
| AU2976000A (en) * | 1999-01-27 | 2000-08-18 | Regents Of The University Of California, The | Assays for sensory modulators using a sensory cell specific g-pr otein beta subunit |
| US6929925B1 (en) | 1999-01-27 | 2005-08-16 | The Regents Of The University Of California | Assays for sensory modulators using a sensory cell specific G-protein beta subunit |
| TW201006846A (en) | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
| ATE366261T1 (de) * | 2000-03-28 | 2007-07-15 | Lexicon Genetics Inc | Humane 7-transmembranproteine und dafür codierende polynukleotide |
| EP1301595A2 (en) * | 2000-05-22 | 2003-04-16 | Incyte Genomics, Inc. | G-protein coupled receptors |
| AU2001266975A1 (en) * | 2000-06-16 | 2002-01-02 | Incyte Genomics, Inc. | G-protein coupled receptors |
| CA2424821A1 (en) * | 2000-10-10 | 2002-04-18 | Pe Corporation (Ny) | Gene encoding a human g-protein coupled receptor and its use |
| TW201022287A (en) | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US7301009B2 (en) | 2001-06-26 | 2007-11-27 | Senomyx, Inc. | Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli |
| US7309577B2 (en) | 2001-03-07 | 2007-12-18 | Senomyx, Inc. | Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste |
| US20080244761A1 (en) | 2001-03-07 | 2008-10-02 | Senomyx, Inc. | T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
| US7368285B2 (en) | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| US7763431B1 (en) | 2001-03-07 | 2010-07-27 | Senomyx, Inc. | Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste |
| WO2002086079A2 (en) * | 2001-04-20 | 2002-10-31 | Mount Sinai School Of Medicine | T1r3 a novel taste receptor |
| US7803982B2 (en) | 2001-04-20 | 2010-09-28 | The Mount Sinai School Of Medicine Of New York University | T1R3 transgenic animals, cells and related methods |
| EP2327985B2 (en) | 2001-06-26 | 2019-08-21 | Senomyx, Inc. | T1R Hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
| DK2327985T3 (en) | 2001-06-26 | 2016-09-05 | Senomyx Inc | H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds |
| JP5001512B2 (ja) * | 2001-06-26 | 2012-08-15 | セノミックス インコーポレイテッド | Ｔ１ｒヘテロオリゴマー味覚受容体及び前記受容体を発現する細胞系並びに味覚化合物の特定のためのその使用 |
| WO2003025137A2 (en) * | 2001-09-18 | 2003-03-27 | Irm, Llc | Sweet taste receptors |
| AU2004256023B2 (en) | 2003-06-27 | 2008-03-13 | Monell Chemical Senses Center | Taste receptors of the T1R family from domestic cat |
| NZ619746A (en) | 2003-08-06 | 2014-05-30 | Senomyx Inc | Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof |
| US8796441B2 (en) | 2005-04-13 | 2014-08-05 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human sweet and umami taste receptor variants |
| US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
| US20110097741A1 (en) * | 2006-04-20 | 2011-04-28 | Jay Patrick Slack | Partial t1r2 nucleic acid sequence, receptor protein and its use in screening assays |
| US8148536B2 (en) | 2006-04-21 | 2012-04-03 | Senomyx, Inc. | Comestible compositions comprising high potency savory flavorants, and processes for producing them |
| US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
| WO2013022948A1 (en) | 2011-08-08 | 2013-02-14 | The Coca-Cola Company | Cell lines comprising endogenous taste receptors and their uses |
| US9804157B1 (en) | 2013-03-15 | 2017-10-31 | Senomyx, Inc. | Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives |
| WO2021150686A1 (en) | 2020-01-22 | 2021-07-29 | Firmenich Incorporated | High-sensitivity detection of gpcr activity and uses thereof |
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| US4146501A (en) * | 1975-12-12 | 1979-03-27 | Henkin Robert I | Process for isolating and purifying taste bud receptors for screening and evaluating tastants |
| US5688662A (en) * | 1992-04-09 | 1997-11-18 | Linguagen Corporation | Gustducin polynucleotides, vectors, host cells and recombinant methods |
| US7368285B2 (en) * | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| KR101511394B1 (ko) * | 2007-01-18 | 2015-04-10 | 지보당 에스아 | 키메라 우마미 미각 수용체, 이를 코딩하는 핵산 및 이의 용도 |
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1999
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- 1999-07-27 EP EP99937576A patent/EP1100810A4/en not_active Ceased
- 1999-07-27 IL IL14097999A patent/IL140979A0/xx unknown
- 1999-07-27 JP JP2000562389A patent/JP2002521049A/ja not_active Withdrawn
- 1999-07-27 BR BR9912545-5A patent/BR9912545A/pt not_active Application Discontinuation
- 1999-07-27 CA CA2335318A patent/CA2335318C/en not_active Expired - Lifetime
- 1999-07-27 CA CA2776054A patent/CA2776054C/en not_active Expired - Lifetime
- 1999-07-27 AU AU52381/99A patent/AU753703B2/en not_active Expired
- 1999-07-27 WO PCT/US1999/017099 patent/WO2000006592A1/en not_active Ceased
- 1999-07-27 US US09/361,652 patent/US20030036630A1/en not_active Abandoned
- 1999-07-27 KR KR1020017001140A patent/KR100602857B1/ko not_active Expired - Fee Related
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2001
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2005
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2009
- 2009-06-17 JP JP2009144758A patent/JP2009261399A/ja not_active Withdrawn
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| CA2335318A1 (en) | 2000-02-10 |
| NO20010363D0 (no) | 2001-01-22 |
| WO2000006592A1 (en) | 2000-02-10 |
| ZA200100401B (en) | 2001-10-31 |
| CA2776054A1 (en) | 2000-02-10 |
| JP2002521049A (ja) | 2002-07-16 |
| CA2776054C (en) | 2016-08-30 |
| AU5238199A (en) | 2000-02-21 |
| WO2000006592A9 (en) | 2000-11-02 |
| BR9912545A (pt) | 2001-10-30 |
| JP2009261399A (ja) | 2009-11-12 |
| CN1317010A (zh) | 2001-10-10 |
| EP1100810A4 (en) | 2002-09-18 |
| US20070185312A1 (en) | 2007-08-09 |
| IL140979A0 (en) | 2002-02-10 |
| EP1100810A1 (en) | 2001-05-23 |
| NO20010363L (no) | 2001-03-26 |
| US20030036630A1 (en) | 2003-02-20 |
| US20090148948A1 (en) | 2009-06-11 |
| CN1198836C (zh) | 2005-04-27 |
| KR20010085306A (ko) | 2001-09-07 |
| AU753703B2 (en) | 2002-10-24 |
| IL140979A (en) | 2008-07-08 |
| KR100602857B1 (ko) | 2006-07-20 |
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