KR100513616B1 - Composition for external application to the skin containing the active ingredients of green tea - Google Patents

Abstract

The present invention relates to an external composition for skin containing green tea ( Camellia sinensis ) component, and more particularly, containing theanine and catechin in the form of a single or a mixture of subcutaneous fat decomposition effect of adipocytes, Provided is a skin external composition for preventing fat decomposition and obesity excellent in removing the cellulite.

Description

Composition for external application to the skin containing the active ingredients of green tea}

The present invention relates to an external composition for skin containing green tea ( Camellia sinensis ) component, and more particularly, containing theanine and catechin in the form of a single or a mixture of subcutaneous fat decomposition effect of adipocytes, Provided is a skin external composition for preventing fat decomposition and obesity excellent in removing the cellulite.

In the present invention, it is characterized by applying green tea, which was mainly used for drinking, to external preparation.

There are about 20 billion fat cells in the human body, and it is responsible for accumulating or releasing energy in mammals. Within these cells, there are complex control principles for the accumulation and release of energy. If the supply is much greater than the demand for energy, it is stored as triglycerides in adipocytes and then broken down into free fatty acids and glucose when energy is depleted. It is used. Obesity is caused by excessive energy accumulation due to the imbalance of this process, and is believed to be due to the increase or increase in the size of fat cells.

Women's interest in a beautiful body is rapidly increasing not only due to the increase in obesity caused by abundant life, but also due to the improvement of social status, economic independence, and the quality of life of the woman, thus removing excessive subcutaneous fat and skin elasticity. There is also a growing interest in slimming and anti-celullite cosmetics that are effective in promoting.

Cellulite occurs only in women's skin and subcutaneous fat, and is a phenomenon of rugged skin like rough orange peel due to circulatory disorder caused by excessive fat and waste accumulation. The cause of the cellulite is different from the simple obesity, but the root cause of the increase or hypertrophy of fat cells, so it is ultimately helpful to make a slim and smooth body by dissolving and discharging fat in fat cells Can give

Most known lipolysis promoting substances are methylxanthine substances such as caffeine and theophylline, and adenylate cyclase, an enzyme closely related to lipolysis in fat cells. Lipolytic effect through the promotion of) or the inhibitory effect of phosphodiesterase (phosphodiesterase). However, they are known to have a wide range of adverse reactions, such as addictive substances, and to induce bronchial expansion or worsen premenstrual syndrome, so there is no clear guarantee on safety. Therefore, there is a need to develop a new substance that is equivalent to or higher than the above substances but is safer for the human body. Meanwhile, theanine in the preceding obesity-related patent for improving obesity is emerging. It is known that blood cholesterol and visceral fat levels were significantly reduced in rats ingested (Japanese Patent No. 2000-53568), but studies on the body fat of deanine are still insignificant. In addition, the catechin component of green tea has recently been reported to increase the consumption of fat by promoting exothermic reactions in the brown fat cells of the body (International Journal of Obesity, 2000). Little is known about its efficacy and its regulatory mechanisms.

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Accordingly, the present inventors have extensively researched and examined in order to develop an active ingredient that is safe for the human body while promoting lipolysis and inhibiting the differentiation of fat cells in adipocytes, and thus, the active ingredients of green tea, especially theanine and When catechin is applied to the skin, it has an excellent effect of promoting the breakdown of triglycerides in adipocytes, resulting in the reduction of the size of adipocytes and the prevention of further adipocytes, thereby reducing the thickness of subcutaneous fat and cellulite. The present invention was completed by discovering that it helps to create and maintain a slim and elastic body.

Accordingly, it is an object of the present invention to provide a novel use of theanine, which is effective in promoting lipolysis, and catechin, which is effective in inhibiting adipocyte differentiation, in green tea.

It is another object of the present invention to provide an external composition for skin that reduces subcutaneous fat by containing the above ingredients, reduces roughness at the cellulite site of women and has excellent efficacy in restoring elasticity.

Still another object of the present invention is to provide a method for removing body fat which promotes triglyceride breakdown in cells by applying the above ingredients to the skin.

Still another object of the present invention is to provide a method for preventing obesity by preventing the differentiation and hypertrophy of fat cells by applying the above ingredients to the skin.

In order to achieve the above object, the composition of the present invention by inhibiting the differentiation of theanine and fat cells activating the metabolism of fat cells constituting the subcutaneous fat layer with the effect of promoting lipolysis in cells to prevent the occurrence of obesity It is characterized by containing catechins effective in blocking (catechin) alone or in the form of a mixture.

In particular, the present invention is characterized in that the green tea components used for food use are applied to the external preparation for skin.

Hereinafter, the present invention will be described in more detail.

Green tea ( Camellia sinensis ) used in the present invention is an evergreen shrub of the Camellia family and is generally referred to as green tea, which is processed without fermenting its shoots or leaves during the manufacturing process. It is said that green tea has been drunk since the Chinese peasant era in 2700 BC, and our country has been drinking tea since the time of King Silla Deok. Green tea also contains catechins, flavonoids, theanine, GABA, caffeine, caffeine, tannins, and other vitamins. It is known to have various effects such as lowering and enhancing immune function, and recently, it has been reported to be effective in diet. In particular, the catechin component is a major functional component of green tea exhibiting a variety of pharmacological action, such as antioxidant, anti-cancer, antibacterial, inhibiting the occurrence of heart disease. The catechins of green tea known to date are (+) catechin (C), (-) epicatechin (EC), (-) epigallocatechin-3-gallate (EGCG), (+) epigallocatechin (EGC), (-) epicatechin gallate ( ECG). Catechin used in the present invention was extracted from green tea, EC, EGC, EGCG, ECG as a main component, but is not limited to the catechin.

On the other hand, theanine, one of the flavourful amino acids of green tea, has the effect of suppressing the excitement induced by caffeine, and is actually an alpha wave that appears in a comfortable and stable state when ingested by humans. An increase in the appearance of was observed (Nippon Nogeikagaku Kaishi. 72 (2), 153-157 (1998)). Deanine used in the present invention may be any of L-form extracted from green tea, or L-theanine, D-theanine, DL-theanine, which are chemically synthesized, and may be other manufacturing methods and are not particularly limited.

Extraction method of the present invention can be used by the appropriate selection and application of methods commonly known in the art.

The composition containing the deanine and catechin of the present invention alone or in the form of a mixture is excellent in the effect of degrading triglycerides in adipocytes. That is, by breaking down triglycerides in adipocytes into free fatty acids and glycerol, there is an effect of promoting lipolysis. This is because the composition of the present invention increases the expression of β ₃ -adrenergic receptor in 3T3-L1 cells differentiated into adipocytes, thereby promoting the process of degrading triglycerides in cells. Therefore, upon application of the composition containing the deanine and catechin of the present invention alone or in a mixture, triglyceride breakdown in the cells is promoted to effectively remove body fat.

In addition, the composition containing the deanine and catechin of the present invention alone or in the form of a mixture is very excellent in inhibiting the differentiation of adipocytes and the accumulation of triglycerides in adipocytes. That is, it is effective in preventing the fat cells constituting the subcutaneous fat from bloating or increasing in number. This is because the composition of the present invention dramatically reduces the activity of glycerol-3-phosphate dehydrogenase (GPDH) enzyme, which is a marker of adipocyte differentiation, in 3T3-L1 cells differentiated into adipocytes. Therefore, when the composition is applied to the skin containing the deanine and catechin of the present invention alone or in the form of a mixture, it is possible to effectively block the increase of body fat by inhibiting the production and hypertrophy of fat cells.

In addition, the use of the composition according to the present invention is not limited to the effect of reducing the subcutaneous fat, anti-cellulite cosmetics excellent in the recovery of elasticity and smoothness by reducing the bumps caused by fat cells enlarged in the cellulite site of women It can also be used for the purpose of manufacturing. In particular, since the composition of the present invention is a natural extract extracted from green tea, almost no irritation to the skin can be used safely.

On the other hand, the composition of the present invention is a substance capable of resolving obesity and preventing obesity, as well as having a function of decomposing and discharging triglycerides already excessively accumulated in mature adipocytes, and thus preventing differentiation into adipocytes. That is, while the prior art is a passive concept that aims at only one effect, such as differentiation of fat cells or promotion of lipolysis, the present invention may decompose fats of fat cells, which are already present, while preventing the production of fat cells. Obesity relieves and inhibits substances.

The method of mixing the components in the composition containing the deanine and catechin of the present invention alone or in the form of a mixture can be used by appropriately selecting and applying a mixing method commonly used in the art, and at this time, other to facilitate mixing. An additive can be suitably selected and mix | blended.

The composition containing the deanine and catechin of the present invention alone or in a mixture preferably contains 0.0001 to 20% by weight based on the total weight of the composition, but is not limited thereto.

The topical skin composition of the present invention contains deanine and catechin alone or in the form of a mixture, thereby reducing the subcutaneous fat and improving the slim body, and the slimming effect of breaking down the subcutaneous fat when administered as a skin formulation, and the removal of cellulite. Excellent effect and elasticity enhancing effect.

The external preparation composition for skin containing the active ingredient of green tea of the present invention is not particularly limited as long as it is intended for the decomposition of fat and the elasticity, beauty and softness of female skin. Specifically, for example, it may be a cosmetic composition having a formulation of a flexible cosmetics, nourishing cosmetics, nourishing lotion, massage cream, nourishing cream, pack, gel or skin adhesive type cosmetics, and also, lotion, ointment, gel, cream, patch Or transdermal dosage forms such as sprays.

In addition, in the topical skin composition of each formulation, other components other than deanine and catechin, which are essential ingredients of the present invention, can be appropriately selected and blended by those skilled in the art without difficulty according to the formulation or purpose of use of other skin external preparations, In this case, synergistic effects may occur when applied simultaneously with other raw materials.

Hereinafter, although an Example and a comparative example are given and this invention is demonstrated more concretely, this invention is not limited only to these examples.

Preparation Example Extraction of Catechin

10 l of water was added to 2 kg of green tea leaves, and the mixture was left at 80 ° C. for 5 hours. Then, 5 l of water was added to the collected filtrate and the residue, and the filtrates left at 80 ° C. for 3 hours were collected together. The collected filtrates were filtered through filter paper, fractionated with ethyl acetate, concentrated, and then fractionated with chloroform to remove caffeine and concentrated. After passing the separation through the Sepharose column (column), the extract extracted with a 1: 1 mixture of methylene chloride and methanol (methanol) was concentrated at 40 ℃ to obtain a green tea catechin powder (catechin) powder.

Reference Example Differentiation of Adipocytes

3T3-L1 cells, a mouse fibroblast cell line, were loaded with DMEM (Dulbecos modified eagles medium, GIBCO BRL, Life Technologes) medium containing 10% fetal bovine serum (FBS). The well culture plate was attached at 1 × 10 ⁵ cells / well. After 2 days, it was again exchanged with fresh DMEM (containing 10% FBS) medium and incubated for 2 days. The cultured cells were then induced to differentiate into DMEM (containing 10% FBS) containing 1 μg / ml insulin, 0.5 mM IBMX and 0.25 μM dexamethasone, and after 2 days It was again exchanged with insulin-containing DMEM and incubated for 5 days. After 5 days, the cells were exchanged with normal medium (DMEM, containing 10% FBS) and cultured while observing until the cells changed to fat cells.

<Test Example 1> Deanine (Theanine) promoting triglyceride decomposition effect

In order to evaluate the effect of theanine, the main potent ingredient of green tea, on promoting triglyceride breakdown in adipocytes, experiments were performed using 3T3-L1 adipocytes that were differentiated by the method of the reference example.

3T3-L1 adipocytes were washed twice with PBS (phosphate buffered saline), and colorless DMEM containing 0.5% bovine serum albumin (BSA) without fatty acids was added and used in each experiment. Deanine was purchased from Yul Electric Co., Ltd. (more than 97%), and the glycerol was measured by color reaction method using GPO-trinder kit purchased from Sigma (St. Louis, MO, USA). The absorbance was measured at 540 nm using a reader. At this time, the control group used only the medium without the test substance or the comparative substance, and when the result value is 100%, other values are represented. In addition, caffeine was treated with the same concentration as a positive comparison group, and the degree of lipolysis was determined by measuring the concentration of glycerol released from the adipocytes into the culture solution. The results are shown in Figure 1 below.

As can be seen in Figure 1, the group treated with deanine extracted from green tea was found to significantly increase the concentration of glycerol released from the adipocytes into the culture compared to the control group. In particular, the deanine was found to have a better lipolysis effect at the same concentration than the positive control caffeine known to the lipolysis effect even without high cytotoxicity at high concentrations.

<Test Example 2> Theanine β ₃ -adrenergic receptor expression control effect

In order to investigate the mechanism of promoting triglyceride breakdown in the adipocytes of theanine, which is the main potent ingredient of green tea, 3T3-L1 adipocytes were differentiated by the method of the reference example. Next, the same deanine and other comparative substances (caffeine, control) as in Test Example 1 were treated at a concentration of 0.005%, and RNA was extracted from the cells after 24 hours, and RT-PCR was performed. The results are shown in FIG. 2.

The RT-PCR kit was purchased from TaKaRa, and the primer of β ₃ -adrenergic receptor was purchased from bioneer.

As can be seen in FIG. 2, it can be seen that the expression of β ₃ -adrenergic receptor, which is a signal of lipolysis in adipocytes, is significantly increased by the treatment of deanine, and thus, the lipolytic effect of deanine is increased. It was confirmed that this is due to the increased expression of the receptor.

<Test Example 3> Green tea catechin inhibitory effect of adipocyte differentiation

In order to evaluate the effect of catechin on the promotion of neutral fat production in adipocytes, culture and absorbance measurements using fibroblasts were performed.

The fibroblasts 3T3-L1, differentiated into adipocytes in the same manner as the reference example, were washed three times with PBS and harvested with an extraction buffer (20 mM Tris, 1 mM EDTA and 1 mM 2-mercaptoethanol). The collected cells were passed six times with G26 needle on ice, then 15000 X g , Centrifuged at 4 ° C. for 3 minutes and only the supernatant was taken and used in the experiment.

In order to measure the activity of glycerol-3-phosphate dehydrogenase (GPDH), the cell extract prepared above was prepared with 0.1 M triethanolamine, 2.5 mM EDTA, 0.1 mM 2-mercaptoethanol, 125 uM nicotinamide adenine dinucleotide (reducd form), and 100 uM DHAP (DuAP). GPDH assay buffer containing dehydroxyacetone phosphate) was added to measure the decrease in absorbance at 340 nm for 2 minutes. The change amount was expressed as dA / min value per 1 mg of protein, and the control group used only the medium without addition of the test substance or the comparative substance, and when the result value was 100%, other values were converted. The results are shown in FIG. 3.

As can be seen in Figure 3, when the catechin extracted from the green tea was treated during the differentiation of 3T3-L1 cells it was observed a phenomenon that the differentiation is significantly inhibited compared to the control.

Experimental Example 4 Inhibitory Effect of Theanine and Catechin on Triglycerides

In order to evaluate the effect of promoting the neutral fat production in adipocytes by green tea theanine and catechin, culture and absorbance measurement experiments using fibroblasts were performed.

Cell extracts prepared in the same manner as in Test Example 3 were subjected to color reaction of triglycerides using GPO-trinder kit purchased from Sigma Co., Ltd. (St. Louis, MO, USA), and then absorbance was measured with an ELISA reader at 540 nm. It was. The results are shown in FIG. 4.

As can be seen in Figure 4, when the deionine and catechin, the representative active substances of green tea were treated when the differentiation of 3T3-L1 cells, respectively, the amount of triglycerides could be observed compared to the control group, two kinds When the components were combined, it was confirmed that the degree of triglyceride accumulation was significantly reduced.

<Test Example 5> Evaluation of skin irritation degree of green tea potency component

From the results of abnormality in the skin of New Zealand white rabbit, the stimulation degree of green tea potency component was observed as follows.

Excipients (vehicle) or 10% theanine and 10% catechin (co) alone or in combination was applied to the skin of New Zealand white rabbits for a total of eight times four days at intervals of twice a day. The cumulative skin irritation index was calculated by accumulating erythema, skin formation score, and edema score after application. The cumulative skin irritation index was evaluated according to the criteria shown in Table 1 below, and the results are shown in Table 2 below. The irritation index shown in the results was based on the commonly used method of Draize's primary Irritation Index (P.I.I.) calculation (Draize, J.H., Appraisal of the safety of chemical in foods, drugs and cosmetics).

Degree of skin irritation grade Erythema and skin formation No erythema 0 Very mild erythema (only visible to the naked eye) One Clear erythema 2 Strong erythema in severity 3 Deep red erythema and crust formation 4 Edema No edema 0 Very mild edema, barely visible to the naked eye One Clear edema (distinguishable from ambient) 2 Severe edema (when swelling about 1 mm) 3 Strong edema (swelling more than 1 mm and extended outside the exposed area) 4 Note: Skin primary stimulation index = (average of sum of erythema and edema scores) / 4

Skin Primary Irritation Index (0 ~ 4) Excipient 0.7 10% theanine solution 0.7 10% catechin solution 0.8 10% theanine / 10% catechin solution 0.8

As can be seen in Table 2, the green tea potency component was found to be almost no skin irritation compared to the control.

Example 1 and Comparative Example 1

Example 1 and Comparative Example 1 were prepared in the form of slimming / anti cellulite lotion with the composition of Table 3 below.

ingredient Content (% by weight) Example 1 Comparative Example 1 Purified water To 100 To 100 Theanine 1.00 - Catechin 1.00 - Vegetable Cured Oil 1.50 1.50 Stearic acid 0.60 0.60 Polyglycerol-10 Pentastearic & Behenyl Alcohol & Sodium Stearoyl Lactylate 1.00 1.00 Arachidil Behenyl Alcohol & Arakidil Glucoside 1.00 1.00 Cetylaryl Alcohol & Cetearyl Glucoside 2.00 2.00 PEG-100 stearate & glycerol oleate & propylene glycol 1.50 1.50 Caprylic / Capric Triglycerides 4.00 4.00 Meadowfoam fruit oil 3.00 3.00 Cetyl octanoate 4.00 4.00 Cyclomethicone 6.00 6.00 Methylparaben 0.20 0.20 Profile paraben 0.10 0.10 Disodium EDTA 0.02 0.02 Trimethanol amine 0.13 0.13 glycerin 8.00 8.00

<Test Example 6> Slimming effect of green tea potency

For women with topical obesity or cellulite, BMI (Body Mass Index, body weight (kg) / height (m) ² ), 50 adult women aged 25-35 with 21-27 days, morning and evening for 8 weeks Using the lotion of Example 1 and Comparative Example 1 together with the massage of the user at home on one thigh twice, before and after use for 8 weeks by the device evaluation, evaluation by the researcher (dermatologist) and questionnaire evaluation Judging whether the effect.

[Thigh circumference]

The thigh circumference was measured after marking a certain part of both thighs using a tape measure (unit: ㎝), and the measuring area of the thigh was measured at two parts, that is, the upper part and the middle part of the thigh. The obtained values were analyzed by using the Student t test or the Wilcoxon test with the two-sided test. The statistical significance was analyzed (significance level α = 0.05). The Levene test and the Kolmogorov-Smirnov test were used to confirm the dispersion and homogeneity of the distribution, respectively. The results are shown in FIG. 5.

[Thickness of cellulite]

Ultrasound-EuB 415 US scanner was used for the measurement of the thickness of subcutaneous fat layer and infiltrated cellulite by ultrasound, and the obtained values were bilaterally tested using the Student t test or Wilcoxon test. Statistical significance was analyzed (significance level α = 0.05). The Levene test and the Kolmogorov-Smirnov test were used to confirm the dispersion and homogeneity of the distribution, respectively. The results are shown in FIGS. 7 to 8.

[Visual evaluation]

Visual evaluation by the investigator was evaluated by elasticity and cellulite degree. The obtained values were analyzed by the Wilcoxon test using the Wilcoxon test and compared with before and after use (significance level α = 0.05). Elasticity was evaluated in nine stages from the lowest to the highest nine points, and cellulite was evaluated in five stages from zero to four points by visual evaluation. The results are shown in FIG. 7.

[User rating]

The evaluation by the user was mainly focused on self-assessment and questionnaire evaluation. Self-assessment indicators were scored in 10 levels from the lowest 0 to the highest 9, and the indices were elasticity and cellulite. The results are shown in Table 4 and FIG. 8.

[Skin Safety Assessment]

During the test period, the dermatologist was referred to evaluate skin safety by observing skin irritation and side effects. Evaluation was carried out in the same manner as in Test Example 5, the evaluation criteria were applied in the same manner as in Table 1. The results are shown in Table 5 below.

Survey Evaluation Items % Of respondents yes Freshness 96 Smother skin 85 Comfort 80 Soft skin 72 Beautiful skin 69

Skin Primary Irritation Index (0 ~ 4) Excipient 0.7 10% theanine solution 0.7 10% catechin solution 0.8 10% theanine / 10% catechin solution 0.8

As a result of measuring and comparing the thigh circumference 8 weeks after using Example 1 and Comparative Example 1, as shown in Figure 5, when using Example 1 added the green tea potency component compared to Comparative Example 1 The thigh circumference decreased by 1.0 cm, indicating a statistically significant result.

As can be seen in Figure 6, compared to before use in the thigh using Example 1 showed a subcutaneous fat decreased 3.2% showed a statistically significant result, while in the thigh using Comparative Example 1 was a significant change It was confirmed that none.

As can be seen in FIG. 7, the decrease in cellulite (-28%) and the increase in skin elasticity (+ 18%) were statistically significant at the site of Example 1 compared to Comparative Example 1 in the efficacy evaluation by the researcher. Appeared.

As shown in FIG. 8, in the evaluation of efficacy by the user, the cellulite reduction effect (-31%) and skin elasticity increase (+ 19%) were statistically significant at the site using the formulation example.

As can be seen in Table 4, in the user's feeling evaluation according to the user, most of the respondents felt refreshed (96%) and smooth skin (85%) after using the composition containing green tea deanine and catechin for 8 weeks. In addition, more than half of the respondents answered that they were comfortable (80%), soft skin (72%) and beautiful skin (69%).

As can be seen in Table 5, the green tea potency component was found to have little irritation in human skin compared to the control.

From the above results, it can be seen that the composition containing green tea deanine and catechin is effective for reducing subcutaneous fat, reducing cellulite and enhancing elasticity of women. In addition, it was found that the feeling of using the composition is very excellent.

As described above, the present invention has the effect of promoting the process of decomposing triglycerides accumulated in adipocytes into glycerol and free fatty acids and releasing them, as well as reducing the subcutaneous fat layer to produce a slim body. By providing an external composition for skin that can be applied to the production of a new concept of anti-cellulite cosmetics by containing a green tea potent ingredient that has an effect of reducing cellulite that causes uneven skin and makes elastic and smooth skin, It is a very useful invention in the cosmetic manufacturing industry.

1 is a graph showing the triglyceride degrading effect of theanine in the green tea component.

Figure 2 is a graph showing the effect of the expression of β ₃ -adrenergic receptor (β ₃ -adrenergic receptor) of theanine in the green tea component.

        A: Control

        B: caffeine 0.005% treatment group

        C: theanine 0.005% treatment group

3 is a graph showing the effect of catechin (catechin) adipocyte differentiation of green tea components.

       Figure 4 is a graph showing the results of a cell experiment to determine the synergistic inhibitory effect of the accumulation of triglycerides in the adipocytes of theanine and catechin in the green tea component.

FIG. 5 is a graph showing a decrease in thigh circumference after use of the topical skin preparation composition containing theanine and catechin.

Figure 6 is a graph showing the results of the ultrasonic measurement for the subcutaneous fat reduction effect after using the topical skin composition of the present invention containing theanine and catechin.

7 is a graph showing the results of the naked eye evaluation of the researchers about the slimming effect after using the topical skin composition of the present invention containing theanine and catechin.

FIG. 8 is a graph showing visual evaluation results of users about the slimming effect after using the external preparation for skin composition of the present invention containing theanine and catechin.

Claims (9)

As a cosmetic composition for lipolysis, containing theanine and catechin as an active ingredient in an amount of 0.0001 to 20% by weight based on the total weight of the composition to promote triglyceride decomposition in the cell, the deanine is fat cells Increasing the expression of β ₃ -adrenergic receptor (β ₃ -adrenergic receptor) of the skin cosmetic composition for intracellular lipolysis, characterized in that to promote lipolysis. The skin cosmetic composition according to claim 1, wherein the deanine and catechin are extracted from green tea. The skin cosmetic composition according to claim 1, wherein the theanine is at least one selected from L-theanine, D-theanine, and DL-theanine. The method of claim 1, wherein the catechin (catechin) is (+) catechin (C), (-) epipicatechin (EC), (-) epigallocatechin-3-gallate (EGCG), (+) epigallocatechin (EGC), and ( Skin cosmetic composition, characterized in that at least one selected from epicchinchin gallate (ECG). delete delete delete In the anti-cellulite skin cosmetic composition, theanine and catechin are included as an active ingredient in an amount of 0.0001 to 20% by weight based on the total weight of the composition, thereby reducing cellulite to enhance skin smoothness. Skin cosmetic composition for anti-cellulite, characterized in that. delete