KR100475196B1 - The health-supporting food being effective the hairloss preventation or hair-growth and its preparation method - Google Patents
The health-supporting food being effective the hairloss preventation or hair-growth and its preparation method Download PDFInfo
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- KR100475196B1 KR100475196B1 KR10-2002-0041048A KR20020041048A KR100475196B1 KR 100475196 B1 KR100475196 B1 KR 100475196B1 KR 20020041048 A KR20020041048 A KR 20020041048A KR 100475196 B1 KR100475196 B1 KR 100475196B1
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/318—Foods, ingredients or supplements having a functional effect on health having an effect on skin health and hair or coat
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
본 발명은 정제된 심층수(선도액), 유기 게르마늄(Ge-132) 및 한약재를 주재료로 하여 탈모방지 및 발모에 유용한 효과를 나타내는 건강보조식품 및 이의 제조방법에 관한 것으로, 해저 600m의 심층수와 1400m의 심층수를 정제하여 적정한 비율로 혼합한 정제된 심층수(선도액) 60 ∼ 74.5중량%, 생지황, 당귀, 사인, 수지황, 백작, 쌍심자, 복신, 목과, 황정, 하수오, 토사자, 보골지, 구기자, 우슬, 대사석, 죽엽, 감초, 수지, 생황기, 명천마, 동충하초, 여정자, 육종용, 복령, 도인, 당삼, 파극천, 두충, 산약, 녹각고, 소희향, 수오, 측백엽, 공쇄보, 대추, 천동, 맥동, 원지, 백자인, 오미자, 현삼, 강귀, 길경, 사삼, 흑대두, 고삼, 백선피, 백출, 방풍, 진피 등으로 구성되는 군으로부터 선택된 적어도 8종 이상의 한약재 추출물 25 ∼ 39.5중량% 및 유기 게르마늄(Ge-132) 0.5 ∼ 15중량%로 구성되어지되 정제된 심층수(선도액), 한약재 추출물 및 유기 게르마늄(Ge-132)을 혼합하여 본 발명의 건강보조식품을 얻고, 이를 복용하게 하므로서 탈모를 방지하고 발모을 용이하게 할 수 있었다.The present invention relates to a health supplement food and a method for producing the same, which are useful for preventing hair loss and hair growth using purified deep water (freshness liquid), organic germanium (Ge-132) and herbal medicine as main ingredients, and a depth of 600m deep sea water and 1400m 60 to 74.5% by weight of purified deep water (freshening solution), fresh sulfur, Angelica, sinus, sulphur, earl, bicon, fuxin, tree, yellow, sewage, earth and sand, bogol, Gugija, hyssop, metabolic stone, bamboo leaf, licorice, resin, fresh yellow, Myeongcheonma, Cordyceps sinensis, itinerary, breeding, Bokryong, Doin, Dangsam, Paekcheoncheon, Tofu, Sanctuary, green algae, Sohyang, Shou, baekyeoppo 25 ~ 39.5% by weight of at least 8 kinds of herbal extracts selected from the group consisting of jujube, cheondong, pulsating, raw paper, white porcelain, schisandra chinensis, hyeonsam, gangwi, gilkyung, sasam, black soybean, red ginseng, baekseonpi, baekchul, windproof, dermis And organic germanium (Ge-132) 0.5 to It is composed of 15% by weight, but purified deep water (preparative solution), herbal extracts and organic germanium (Ge-132) to obtain the health supplement of the present invention, by taking it to prevent hair loss and facilitate hair growth there was.
Description
본 발명은 정제된 심층수(선도액), 유기 게르마늄(Ge-132) 및 한약재를 주재료로 하여 탈모방지 및 발모에 유용한 효과를 나타내는 건강보조식품 및 이의 제조방법에 관한 것으로, 좀 더 구체적으로는 해저 600m의 심층수와 1400m의 심층수를 정제하여 적정한 비율로 혼합한 정제된 심층수(선도액) 60 ∼ 74.5중량%, 생지황, 당귀, 사인, 수지황, 백작, 쌍심자, 복신, 목과, 황정, 하수오, 토사자, 보골지, 구기자, 우슬, 대사석, 죽엽, 감초, 수지, 생황기, 명천마, 동충하초, 여정자, 육종용, 복령, 도인, 당삼, 파극천, 두충, 산약, 녹각고, 소희향, 수오, 측백엽, 공쇄보, 대추, 천동, 맥동, 원지, 백자인, 오미자, 현삼, 강귀, 길경, 사삼, 흑대두, 고삼, 백선피, 백출, 방풍, 진피 등으로 구성되는 군으로부터 선택된 적어도 8종 이상의 한약재 추출물 25 ∼ 39.5중량% 및 유기 게르마늄(Ge-132) 0.5 ∼ 15중량%로 구성되는 것을 특징으로 하는 탈모방지 및 발모에 효과적인 건강보조식품 및 이의 제조방법에 관한 것이다.The present invention relates to a dietary supplement and a method for preparing the same, which are useful for preventing hair loss and hair growth, using purified deep water (freshness solution), organic germanium (Ge-132), and herbal medicine as main ingredients. 60 to 74.5% by weight of purified deep water (leading liquid), purified from 600m deep water and 1400m deep water, and mixed in an appropriate ratio. Earthenware, Bogolji, Gojija, hyssop, metabolic stone, bamboo leaf, licorice, resin, raw yellow rice, Myeongcheonma, Cordyceps sinensis, Journeyman, breeding, Fuling, Doin, Tangsam, Pageokcheon, Tofu, Sanseng, green tea, Soheehyang, Shou, At least 8 kinds of Chinese herbal extracts selected from the group consisting of baekbaekbyeon, jeongbobo, jujube, cheondong, pulsation, original paper, white porcelain, schisandra, hyeonsam, gangwi, gilkyung, sasam, black soybean, red ginseng, baekseonpi, baekchul, windproof, dermis 25 to 39.5% by weight and organic Reuma titanium (Ge-132) 0.5 ~ 15 effective dietary supplement for hair loss prevention and hair growth, characterized in that consisting of% by weight, and a process for their preparation.
머리털 뿐만 아니라 털은 모두 일정한 성장기간이 지나면 성장이 정지되고 휴지기에 들어가서 탈모하여 다시 털이 나는 일을 되풀이하며,. 이것을 털의 성장 주기라고 하는 데, 눈썹,·속눈썹,·솜털 등의 성장주기는 6개월 이하인데, 머리털은 성장기가 길고(2∼6년 이상) 휴지기가 짧으며(2∼3개월 이하), 1개씩 독립된 성장주기를 가지며, 성인은 머리털의 2 ∼ 5% 정도가 휴지기에 있다고 한다. 휴지기에 들어간 털은 색소가 엷으며, 윤기가 없고, 모근(毛根)도 가늘며, 세발이나 빗질로 쉽게 빠진다. 또, 발열성 질병, 임신, 정신적 스트레스 등에 의하여 성장기의 털이 갑자기 휴지기에 들어가 많이 빠지는 일이 있는데, 원인이 제거되면 회복된다.Not only the hair but also all the hair after a certain period of growth stops growing, enters the resting period, hair loss and repeats the hair again. This is called the hair growth cycle. The growth cycle of eyebrows, eyelashes, and fluffy hair is less than 6 months. Hair growth is long (more than 2 to 6 years) and shortly (2 to 3 months). Each one has an independent growth cycle, and adults have 2 to 5% of their hair at rest. The hairs in the resting phase are light in pigment, lack of shine, thin hair roots, and easily fall off with hair and comb. In addition, due to fever disease, pregnancy, mental stress, growth hair suddenly enters the resting phase, and a lot of missing, it is recovered when the cause is removed.
탈모증은 선천성 탈모증과 후천성탈모증으로 대별되며, 선천성 탈모증은 태어날 때부터 머리카락이 없는 것이고, 후천성탈모증은 점차 나이가 들면서 머리카락이 빠지는 것을 말하며, 후천성 탈모증에는 비반흔성탈모증, 피부의 병변을 발견할 수 없으나 병적인 피부에서의 탈모증 및 반흔성탈모증으로 분류된다.Alopecia is classified into congenital alopecia and acquired alopecia, congenital alopecia is hairless from birth, acquired alopecia refers to hair loss with gradual age, and acne alopecia can cause non- scarring alopecia and skin lesions. But is classified as alopecia and scarring alopecia in pathological skin.
탈모증의 일반적인 원인은 유전적인 요소, 남성호르몬의 과다 분비, 지루성 피부, 스트레스, 바람직하지 못한 식생활 습관, 모발공해, 대기 오염 등이 있으며, 탈모증이 유전된다는 것은 탈모증 자체를 말하는 것이 아니고, 탈모증이 되는 체질을 말하는 것이며, 남성 호르몬이 아무리 많아도 선천적으로 수용체(5 알파 리덕타제)가 결핍이 되는 사람의 경우는 대머리가 없고, 비듬이 피지선에서 나오는 피지와 혼합된 지루가 모공을 막아 모근의 영양장애와 위축작용을 일으킴으로써 머리카락이 빠지게 되며, 스트레스를 방치하게 되면 머리가 빠지게 되고, 이것이 다시 스트레스로 쌓이게 되어 탈모를 더욱 부채질하게 되는 것이며, 식생활 습관 중 육식을 많이 하는 사람은 섭취된 동물성지방으로 인해 혈중 콜레스테롤이 증가하여 모근의 영양공급을 악화시키기 때문에 탈모가 유발되고, 파마, 염색, 드라이 등과 같은 모발 공해도 중요한 탈모의 원인이 되며, 머리카락은 중금속을 흡수하고 배설하는 성질을 지니고 있기 때문에 환경 오염이 심각할 경우 모발에 축적된 중금속은 모발주기의 변화를 가져오는 등 모발에 영향을 끼치게 되어 탈모의 원인으로 작용하기도 한다.Common causes of alopecia include genetic factors, excessive production of male hormones, seborrheic skin, stress, undesirable eating habits, hair pollution, and air pollution, and the fact that alopecia is inherited does not mean alopecia itself. Constitution, and no matter how many male hormones are inherently deficient in receptors (5 alpha reductase), there is no baldness, and seborrhea mixed with sebum from the sebaceous glands from the sebaceous gland blocks pores, Atrophy causes the hair to fall out, and if the stress is left, the hair falls out, and this builds up again as a stress, which causes more hair loss. Cholesterol increases and worsens the nutrition of hair roots Hair loss causes hair loss, and hair coating such as perm, dyeing, and dryness are important causes of hair loss, and hair has the property of absorbing and excreting heavy metals. It can affect the hair and bring about changes in the hair cycle, which can also cause hair loss.
선천성 탈모증은 남성에게보다는 여성에게서 더 많이 나타나고 있고, 유전적인 요인에 의한 것이라고 보여지며, 탈모와 더불어서 몸의 다른 부위에도 이상 증세를 수반하는 경우와 몸의 다른 부위에는 그 어떤 증세도 나타나지 않으면서 어느 한 특정 부위에서만 탈모가 나타나는 경우가 있고, 출생시부터 털이 없었는데 성장하면서도 계속해서 털이 나지 않는 경우와 출생시에는 일반적인 경우처럼 털이 정상적으로 있었는데 이것이 빠지고 난 후부터 털이 제대로 자라지 못하고 비정상적으로 되는 경우가 있으며, 선천성 탈모증은 이렇다 할 치료법은 아직 없는 상태이다.Congenital alopecia is more prevalent in women than in men, and is believed to be caused by genetic factors, and with hair loss accompanied by abnormalities in other parts of the body and no other symptoms in other parts of the body. Hair loss may occur only in one specific area, and there is no hair from birth, but it continues to grow but does not continue to grow, and at the time of birth there was hair normally as usual, but after this fall, hair does not grow properly and becomes abnormal. Alopecia is yet to be cured.
한편, 후천성 탈모증 중 비반흔성 탈모는 머리카락이 빠진 뒤 다시 생성되지 않아 머리카락의 수가 자연스럽게 줄어드는 남성형 탈모증, 머리카락이 원형을 이루며 빠지는 원형 탈모증, 유행성 감기나 독감, 폐렴 등에 의해 심하게 열이 난 뒤 1 ~ 4개월이 흐른 후 갑자기 모발이 빠지기 시작하는 휴지기의 탈모증, 외부로부터의 자극이 원인으로 작용하여 모발이 빠지게 되는 외상성 탈모증, 내분비 이상에 의한 탈모증, 영양장애, 대사장애에 의한 탈모증, 약물에 의한 탈모증이 있으며, 피부병변은 발견할 수 없으나 병적인 피부에서의 탈모증에는 아토피성 피부염, 전신성 에리테마토데스, 피부근염 등과 같은 염증에 의한 탈모증, 한센병, 매독이나 백선 등과 같은 감염에 의한 탈모증, 종양세포의 침투로 인해 모포가 파괴된 뒤 중독성 변화로 탈모 증세가 나타나는 종양에 의한 탈모증이 있고, 반흔성 탈모증에는 흉터로 인하여 나타나는 탈모를 의미한다.On the other hand, non-acne baldness among acquired alopecia is not regenerated after hair falls out, male alopecia in which the number of hair naturally decreases, alopecia areata, in which the hair falls out in a circle, and a severe fever due to a flu, flu, pneumonia, etc. After a period of four months, hair loss in the resting phase of which hair suddenly begins to fall out, traumatic alopecia in which hair is lost due to stimulation from the outside, hair loss due to endocrine disorders, malnutrition, alopecia due to metabolic disorders, and alopecia caused by drugs There is no skin lesion, but alopecia in pathological skin is alopecia due to inflammation such as atopic dermatitis, systemic erythematodes, dermatitis, hair loss due to infections such as Hansen's disease, syphilis or ringworm, and tumor cells. Hair loss due to addictive changes after the follicle is destroyed by the penetration of There is alopecia due to tumors, and alopecia areata, which means hair loss due to scars.
외상성 탈모증에는 모발이 잡아당겨져서 빠지게 되는 견인성 탈모증, 머리가 압박되어 영양이 이르지 못해 생기는 압박성 탈모증, 심한 노이로제 상태에 빠지게 되면 환자 스스로가 자신의 머리카락을 잡아 뜯는 증상에 의한 발모벽(트리코티로마니어)이 있고, 내분비 이상에 의한 탈모증에는 하수체의 기능이 떨어져서 발생하는 탈모, 갑상선의 기능이 떨어져서 발생하는 탈모, 부갑상선의 기능이 떨어져서 오는 탈모, 갑상선의 기능이 항진되어 나타나는 탈모, 당뇨 조절이 제대로 이루어 지지 않아 나타나는 탈모가 있다.Traumatic alopecia includes tractional alopecia, in which the hair is pulled out and pulled out, compressive alopecia caused by uncomfortable nutrition due to the head being compressed, and a hair loss wall caused by the patient's own tearing of his hair if he falls into severe neurosis. Hair loss due to endocrine dysfunction, hair loss caused by poor functioning of the thyroid gland, hair loss due to parathyroid function loss, hair loss due to an overactive thyroid gland, and diabetes control There is hair loss that is not done properly.
이러한 탈모를 치료하는 방법으로 모발에 영양을 공급하는 방법이 많이 이용되고, 최근에는 많은 한방요법이 개발되고 있지만, 그 효과가 만족스럽지 못하여 실제로는 적용에 한계가 있는 실정이다.Many methods of nourishing hair are used as a method of treating hair loss, and many herbal therapies have been developed in recent years, but the effects are not satisfactory, and thus, practical application is limited.
한편, 심층수(선도액)란 해양학적 관점에서 볼 때 해저 1000m 이하의 깊이에 있는 바닷물을 의미하며, 광합성에 의한 유기물 생성이 일어나지 않고 분해가 탁월하며 겨울철 해수 수직 혼합(海水垂直混合)작용이 도달하는 심도(深度)의 이하에 있는 해수로서 바닷물의 깊이에 따라 성분이 다르고, 화학적, 생물학적 위험 및 환경오염 등에 영향을 거의 받지 않아 대단히 깨끗한 물이며, 전형적으로 높은 물리적 안전성을 가진 대단위의 물분자들이 집합체로 뭉쳐져서 낮은 온도에서 형성되어지고, 대량의 미량원소와 미네랄 등을 포함하고 있을 뿐만 아니라 무기영양소금이 포함되어 있어 물부영양화 현상이 뚜렷하여 건강음료로서 사용되어 질 뿐만 아니라 신선한 제품, 음식, 살아있는 조직(장기)의 신선도를 유지시켜주고 피부 표면의 활력을 증진시키는 피부 보호 기능까지 하는 것으로 알려지고 있다.On the other hand, deep water (leading liquid) refers to seawater at a depth of 1,000 m or less from the oceanic point of view, and does not generate organic matter by photosynthesis, is excellent in decomposition and reaches the vertical mixing of seawater in winter. It is a seawater that is below the depth of the seawater, and its composition varies according to the depth of seawater, and it is very clean water because it is hardly affected by chemical, biological hazards and environmental pollution, and large water molecules with high physical safety are typically It is aggregated into aggregates and is formed at low temperature, and contains not only a large amount of trace elements and minerals, but also inorganic nutritional salts, so that water eutrophication is not only used as a health drink, but also fresh products, food, Maintains the freshness of living tissue (organs) and promotes the vitality of the skin surface It is known that until the unit protection.
특히, 기능성 생수 제조나 화장품 생산에 활용되고, 해조류 배양 및 어류사육, 어장 비옥화, 종묘생산 등 수산분야와 화장품, 생수, 비누, 소금, 조미료 등 식품 개발, 의약품 개발, 농업 및 공업분야 등에 활용이 기대되고, 일본에서는 심층수(선도액)를 사용해 만든 부두, 된장, 청주, 절인 반찬, 스포츠 드링크 등이 출시되어 호평을 받고 있다.In particular, it is used for the production of functional bottled water and cosmetics, and it is used for fisheries such as seaweed culture and fish breeding, fertilization of fisheries, seedling production, food development such as cosmetics, bottled water, soap, salt, seasoning, medicine development, agriculture and industrial fields. In Japan, pier, miso, sake, pickled side dishes, and sports drinks made with deep water are popular and popular.
그러나, 아직까지 심층수(선도액)에 대한 많은 연구가 이루어지지 않아 다양한 용도로의 적용이 미미한 상황이고, 탈모증의 치료에 적용된 사례는 전무한 실정이다.However, there have been few studies on the depth of water (leading liquid), and thus the application to various purposes is insignificant.
또한, 한약재들은 다양한 임상 경험을 토대로 하여 다양한 증상에 적용되는 많은 약재들이 있으나, 탈모방지 및 발모에 적용되는 예는 거의 없었다.In addition, there are many medicines that are applied to various symptoms based on various clinical experiences, but few examples are applied to prevent hair loss and hair growth.
그리고, 원자번호 32, 원자량 72.59의 게르마늄은 금속아닌 아금속 원소로 흙속이나 식물에도 함유되어 있으며, 한국 인삼에는 4,189ppm, 마늘 754ppm, 구기자 124ppm, 컴프리 152ppm, 산두근 257ppm이 함유되어 있는데, 게르마늄이 현존하는 항암제와는 다른 차원의 제암효과가 있는 것은 모두가 게르마늄이 지닌 생체내에서 산소를 놀랍도록 풍부하게 해주는 작용과 인터페론 유도체로서의 역할 때문임이 연구 결과 밝혀졌다.Germanium with an atomic number of 32 and atomic weight of 72.59 is a nonmetallic element and is also contained in soil and plants.Korean ginseng contains 4,189ppm, garlic 754ppm, wolfberry 124ppm, comfrey 152ppm, and 257ppm of wild boil. The results show that all of the anticancer effects that differ from existing anticancer drugs are due to the germanium's incredible enrichment of oxygen in vivo and its role as an interferon derivative.
생체란 보는 관점에 따라서는 전기의 극초미립자의 응집체라고 할 수 있다.The living body can be said to be an aggregate of ultrafine particles of electricity depending on the viewpoint.
각 기관, 각 부분은 각각 고유의 응집체로서 기능하고 있다. 때문에 각 부분은 정해진 전위가 있고, 그 전위가 뒤틀린 것이 질병이며, 뇌파측정기나 심전도는 이 전위의 변화를 측정함으로써 장애를 찾아내는 기기이고, 이 뒤틀린 전위를 바로 잡는데 게르마늄이 놀라운 역할을 한다.Each engine and each part function as a unique aggregate. Therefore, each part has a defined potential, and the distorted potential is a disease. An electroencephalogram or an electrocardiogram is a device for detecting a disorder by measuring a change in the potential, and germanium plays an amazing role in correcting the distorted potential.
예를 들어, 암세포의 전위를 살펴보면 다른 정상세포의 전위와는 판이하게 다르다. 암세포는 맹렬한 속도로 세포증식을 계속하기 때문에 그 전위가 높고 심하게 격변하고 있지만 게르마늄은 그 높은 전위를 지닌 암세포로부터 전자를 빼앗아 전위를 낮추는 작용을 하므로서 진행중인 이상세포(암세포)의 활동을 중지시키는 역할을 하며, 암의 전이를 막는 이유이기도 하다.For example, looking at the potential of cancer cells is quite different from the potential of other normal cells. Because cancer cells continue to proliferate at a violent rate, the potential is high and severely deformed, but germanium takes the electrons away from the cancer cells with the high potential and lowers the potential, thereby stopping the activity of abnormal cells (cancer cells) in progress. It is also the reason for preventing cancer metastasis.
게르마늄은 물론 혈액을 비롯한 각 세포는 반도체의 성질을 지니고 있는데 반도체끼리는 그 전자물성으로 보아 공존할 수 없기 때문에 여분의 게르마늄이 체내에 축적될 우려가 전혀 없으며 축적될 수 없다는것은 아무리 많이, 장기간 투여해도 여분의 게르마늄은 배설되기 때문에 부작용이 없다는 뜻이기도 하다.Germanium, as well as blood, each cell has the characteristics of a semiconductor, semiconductors can not coexist in terms of their electronic properties, so there is no risk of excess germanium accumulate in the body, no matter how much, even long-term administration Extra germanium is also excreted, which means there are no side effects.
최근 유기(有機) 게르마늄에 대한 관심이 높아지면서 그의 뛰어난 효능이 인정됨에 따라 기능성 치유물질로 높은 평가받고 있으며, 폐암, 방광암, 유암, 노이로제, 천식, 당뇨병, 고혈압증, 심부전, 축농증, 신경통, 백혈병, 뇌연화증, 자궁근종, 간경병 등 모든 병에서 게르마늄은 놀라운 효과를 나타내고 있다.Recently, as interest in organic germanium increases, its excellent efficacy is recognized, and thus it is highly regarded as a functional healing substance, and it is highly regarded as lung cancer, bladder cancer, cancer, neurosis, asthma, diabetes, hypertension, heart failure, sinusitis, neuralgia, leukemia Germanium has an amazing effect in all diseases, such as cerebral malacia, uterine fibroids and cirrhosis.
특히, 우리들 인간은 살아가기 위해서 음식물을 먹는데, 흡수되지 않은 것은 대변으로 배설되지만 소화기관에서 흡수된 것은 여러가지 과정을 거쳐 산소에 의해 체내에서 연소되며, 최후로 탄산가스와 물이 되어 체외로 배설, 즉, 가스상태의 탄소는 산소와 결합되어 탄산가스로서 호기에 의해 몸 밖으로 나오며, 또 하나의 가스인 수소이온은 산소와 결합되어 물로 땀이나 소변으로 배설되지만 수소는 양이온으로 생체내에서는 전혀 쓸모가 없으며 수소량이 많을수록 중화에 필요한 산소의 양도 많이 요구되므로 이런 경우 게르마늄을 투여하면 산소 대신 수소와 결합하여 배설되기 때문에 몸안의 산소가 낭비됨이 없이 기능회복, 세포수복등 본래의 역할, 건강에 절대적으로 필요한 역할을 하게 되는 것이다.In particular, we humans eat food in order to live, but what is not absorbed is excreted in feces, but what is absorbed in the digestive system is burned in the body by oxygen through various processes, and finally, it is excreted in the body as carbon dioxide and water, That is, gaseous carbon is combined with oxygen and comes out of the body by exhalation as carbon dioxide gas. Another gas, hydrogen ions, is combined with oxygen and excreted in sweat or urine with water, but hydrogen is a cation and is completely useless in vivo. In addition, the higher the amount of hydrogen, the greater the amount of oxygen required for neutralization. In this case, germanium is administered in combination with hydrogen instead of oxygen. Therefore, oxygen is not wasted in the body. It will play the necessary role.
그러나, 이와 같은 게르마늄의 효능이 알려졌음에도 불구하고 아직까지 탈모방지 및 발모에 게르마늄이 적용된 예는 보고된 바 없다.However, although the efficacy of such germanium is known, there has not been reported an example of applying germanium to hair loss prevention and hair growth.
따라서, 본 발명의 목적은 정제된 심층수(선도액), 유기 게르마늄(Ge-132) 및 한약재를 주재료로 하여 건강보조식품으로서의 효능 뿐만 아니라 탈모방지 및 발모에 유용한 효과를 나타내는 건강보조식품을 제공하는 데 있다.Accordingly, an object of the present invention is to provide a dietary supplement that shows useful effects in preventing hair loss and hair growth, as well as efficacy as a dietary supplement based on purified deep water (preparative solution), organic germanium (Ge-132) and herbal medicine as a main ingredient. There is.
본 발명의 다른 목적은 상기 목적의 건강보조식품을 용이하게 제조하는 방법을 제공하는 데 있다.Another object of the present invention to provide a method for easily preparing a health supplement of the above object.
상술한 목적들 뿐만 아니라 용이하게 표출될수 있는 또 다른 목적들을 달성하기 위하여 본 발명에서는 해저 600m의 심층수와 1400m의 심층수를 정제하여 적정한 비율로 혼합한 정제된 심층수(선도액) 60 ∼ 74.5중량%, 생지황, 당귀, 사인, 수지황, 백작, 쌍심자, 복신, 목과, 황정, 하수오, 토사자, 보골지, 구기자, 우슬, 대사석, 죽엽, 감초, 수지, 생황기, 명천마, 동충하초, 여정자, 육종용, 복령, 도인, 당삼, 파극천, 두충, 산약, 녹각고, 소희향, 수오, 측백엽, 공쇄보, 대추, 천동, 맥동, 원지, 백자인, 오미자, 현삼, 강귀, 길경, 사삼, 흑대두, 고삼, 백선피, 백출, 방풍, 진피 등으로 구성되는 군으로부터 선택된 적어도 8종 이상의 한약재 추출물 25 ∼ 39.5중량% 및 유기 게르마늄(Ge-132) 0.5 ∼ 15중량%로 구성되어지되 정제된 심층수(선도액), 한약재 추출물 및 유기 게르마늄(Ge-132)을 혼합하여 본 발명의 건강보조식품을 얻고, 이를 복용하게 하므로서 비반흔성 탈모를 방지하고 발모을 용이하게 할 수 있었다.In order to achieve not only the above-mentioned objects but also other objects that can be easily expressed, in the present invention, 60 to 74.5% by weight of purified deep water (leading liquid), which is mixed at an appropriate ratio by purifying deep water of 600 m and deep water of 1400 m, Fresh green, Angelica, sinus, sujin sulfur, earl, double-headed man, fushin, neck and neck, royal, sesao, earthenware, Bogolji, wolfberry, dew, metabolic stone, bamboo leaf, licorice, resin, yellowish, myeongma, cordyceps, itinerary, Breeding, Bokryeong, Doin, Dangsam, Pageokcheon, Toe Chung, Cheongsam, Green tea, Sohuihyang, Shou, White leaf, Cactus, Jujube, Cheondong, Pulsating, Wonji, White porcelain, Omija, Hyunsam, Gangwi, Gilgyeong, Sasam, Black soybean, Gosam , 25 to 39.5% by weight of at least 8 or more herbal extracts selected from the group consisting of ringworm, baekchul, windproof, dermis and 0.5-15% by weight of organic germanium (Ge-132) ), Herbal Medicine Extract and Organic Crab The mixture of germanium (Ge-132) to obtain the health supplement of the present invention, by taking it it was possible to prevent non- scarring hair loss and facilitate hair growth.
본 발명을 좀 더 상세히 설명하면 다음과 같다.The present invention is described in more detail as follows.
본 발명에 따른 탈모방지 및 발모에 효과적인 건강보조식품은 해저 600m의 심층수와 1400m의 심층수를 정제하여 적정한 비율로 혼합한 정제된 심층수(선도액) 60 ∼ 74.5중량%, 생지황, 당귀, 사인, 수지황, 백작, 쌍심자, 복신, 목과, 황정, 하수오, 토사자, 보골지, 구기자, 우슬, 대사석, 죽엽, 감초, 수지, 생황기, 명천마, 동충하초, 여정자, 육종용, 복령, 도인, 당삼, 파극천, 두충, 산약, 녹각고, 소희향, 수오, 측백엽, 공쇄보, 대추, 천동, 맥동, 원지, 백자인, 오미자, 현삼, 강귀, 길경, 사삼, 흑대두, 고삼, 백선피, 백출, 방풍, 진피 등으로 구성되는 군으로부터 선택된 적어도 8종 이상의 한약재 추출물 25 ∼ 39.5중량% 및 유기 게르마늄(Ge-132) 0.5 ∼ 15중량%로 구성되는 것으로 특징지워진다.Health supplement foods effective for preventing hair loss and hair growth according to the present invention 60 to 74.5% by weight of purified deep water (leading liquid) mixed in a suitable ratio of purified deep sea water of 600m and deep water of 1400m, fresh turmeric, Angelica, sign, water Jihwang, Earl, Bicon, Fuxin, Throat, Hwangjeong, Shouao, Tosa, Bogolji, Gojija, Egret, Metabolic Stone, Bamboo Leaf, Licorice, Resin, Raw Yellow Age, Myeongcheonma, Cordyceps Sinensis, Journeyman, Breeding Dragon, Fuling, Doin, Dangsam , Paekukcheon, Tofu, Sankung, Green tea, Sohuihyang, Shou, White leaf, Cactus, Jujube, Cheondong, Pulsating, Wonji, Baekjain, Schisandra, Hyunsam, Gangwi, Gilgyeong, Sasam, Black soybean, Gosam, Baeksunpi, Baekchul, Windproof It is characterized by consisting of 25 to 39.5% by weight of at least 8 or more herbal extracts selected from the group consisting of dermis, and 0.5 to 15% by weight of organic germanium (Ge-132).
또한, 본 발명에 따른 탈모방지 및 발모에 효과적인 건강보조식품의 제조 방법은 해저 600m의 심층수와 1400m의 심층수를 정제하여 적정한 비율로 혼합한 다음에 별도로 생지황, 당귀, 사인, 수지황, 백작, 쌍심자, 복신, 목과, 황정, 하수오, 토사자, 보골지, 구기자, 우슬, 대사석, 죽엽, 감초, 수지, 생황기, 명천마, 동충하초, 여정자, 육종용, 복령, 도인, 당삼, 파극천, 두충, 산약, 녹각고, 소희향, 수오, 측백엽, 공쇄보, 대추, 천동, 맥동, 원지, 백자인, 오미자, 현삼, 강귀, 길경, 사삼, 흑대두, 고삼, 백선피, 백출, 방풍, 진피 등으로 구성되는 군으로부터 선택된 적어도 8종 이상의 한약재로부터 추출물을 얻은 후에 이를 정제하고, 정제된 심층수(선도액), 한약재 추출물 및 유기 게르마늄(Ge-132)을 균질하게 혼합하는 것으로 특징지워진다.본 발명은 해저 600m의 심층수와 1400m의 심층수를 정제하여 1: 1 비율로 혼합한 정제된 심층수 68중량%, 생지황 15 중량부, 당귀 9 중량부, 사인 6 중량부, 숙지황 15 중량부, 백작 12 중량부, 쌍심자 15 중량부, 복신 15 중량부, 목과 9 중량부 및 황정 15 중량부를 열수 1110 중량부에 투입하여 추출한 10%짜리 한약재 추출물 30중량% 및 카르복시 에틸 게르마늄 32 산화물 2중량%로 구성되는 것을 특징으로 하는 탈모방지 또는 발모에 효과적인 건강보조식품에 관한 것이다. 또한 본 발명은 해저 600m의 심층수와 1400m의 심층수를 취하여 -4 ∼ 0℃의 온도를 유지하면서 1일간 정치하여 침전물을 제거한 후에 여과하는 방법으로 정제한 다음, 해저 600m의 심층수와 1400m의 심층수를 1 : 1의 비율로 혼합하는 단계; 생지황 15 중량부, 당귀 9 중량부, 사인 6 중량부, 숙지황 15 중량부, 백작 12 중량부, 쌍심자 15 중량부, 복신 15 중량부, 목과 9 중량부 및 황정 15 중량부를 열수 1110 중량부에 투입하여 6시간 동안 열수 추출한 다음, 실온으로 냉각하고 1일간 정치한 후, 침전물을 제거하여 10% 짜리 한약재 추출물을 준비하는 단계; 상기 심층수(선도액) 혼합물 68중량%, 상기 한약재 추출물 30중량%와 식물성 카르복시 에틸 게르마늄 32산화물 2중량%를 혼합하고 교반하여 식물성 카르복시 에틸 게르마늄 32산화물이 완전히 용해되고, 각각의 성분들이 균질하게 혼합되도록 하여 제조하는 것을 특징으로 하는 탈모방지 또는 발모에 효과적인 건강보조식품의 제조방법에 관한 것이다.In addition, according to the present invention, a method for preparing a health supplement food effective for preventing hair loss and hair growth is purified by mixing the depth of the seabed 600m deep water and 1400m deep water in an appropriate ratio, and then separately, fresh sulfur, Angelica, sign, resin sulfur, earl, pair Heart, Bokshin, neck, crown, sewage, earthenware, Bogolji, gojija, hyssop, metabolic stone, bamboo leaf, licorice, resin, fresh yellow, Myeongcheonma, Cordyceps sinensis, gourmet, breeding, fueryeong, doin, dangsam, pageokcheon, tofu, Consists of medicine, green tea, sohuihyang, shou, cedar leaf, crushed rice, jujube, cheondong, pulsation, original, white porcelain, schisandra, hyeonsam, gangwi, gilkyung, sasam, black soybean, red ginseng, baekseonpi, baekchul, windproof, dermis After obtaining an extract from at least 8 or more herbal medicines selected from the group consisting of purified and purified, deeply purified water (preparative solution), herbal extracts and organic germanium (Ge-132) is characterized by homogeneously mixing. of 68% by weight of purified deep water, 15 parts by weight of fresh turmeric, 15 parts by weight, sine, 6 parts by weight, 15 parts by weight of sucrose, 12 parts by weight, 12 parts by weight Hair loss, characterized in that consisting of 30 parts by weight of 10% herbal extract extracted by adding 15 parts by weight, 15 parts by weight, 9 parts by weight of neck and 15 parts by weight of yellow water and 1110 parts by weight of hot water and 32% by weight of carboxyethyl germanium 32 oxide. It relates to a dietary supplement that is effective in preventing or hair growth. In addition, the present invention takes 600m deep sea water and 1400m deep water, and after leaving for 1 day while maintaining the temperature of -4 ~ 0 ℃ to remove the precipitate and then purified by the method of filtration, 600m deep sea water and 1400m deep water 1 : Mixing at a ratio of 1; 15 parts by weight of fresh sulfur, 9 parts by weight of Angelica, 6 parts by weight, 15 parts by weight of sucrose, 12 parts by weight, 15 parts by weight of double core, 15 parts by weight of fuxin, 9 parts by weight of neck and 15 parts by weight of yellow water Hot water extraction for 6 hours, followed by cooling to room temperature and allowed to stand for 1 day, after which the precipitate was removed to prepare a 10% herbal medicine extract; 68% by weight of the deep water mixture (priming liquid), 30% by weight of the medicinal herb extract and 2% by weight of vegetable carboxy ethyl germanium 32 oxide are mixed and stirred to completely dissolve the vegetable carboxy ethyl germanium 32 oxide, and the respective components are mixed homogeneously. It relates to a method for producing a health supplement food, which is effective in preventing hair loss or hair growth, characterized in that the manufacturing to.
본 발명에서 사용된 해저 600m의 심층수와 1400m의 심층수의 성분은 다음의 표 1과 같다.The components of the deep sea water of 600m and the deep seawater of 1400m used in the present invention are shown in Table 1 below.
[표 1]TABLE 1
상기 표 1로부터 알 수 있는 바와 같이 심층수(선도액)에는 다양한 무기물 및 미량원소가 다량으로 함유되어 있고, 본 발명에서는 해저 600m의 심층수와 1400m의 심층수를 1 : 3 ∼ 3 : 1의 비율로 혼합하여 사용하였다.As can be seen from Table 1 above, the deep water (leading liquid) contains various inorganic substances and trace elements in a large amount, and in the present invention, the deep water of 600 m and the deep water of 1400 m are mixed at a ratio of 1: 3 to 3: 1. Was used.
해저 600m의 심층수와 1400m의 심층수를 혼합하여 사용하는 것이 바람직하지만 해저 600m 이상의 심층수면 모두 사용이 가능하며, 심층수(선도액)에 함유되어 있는 다양한 무기물 및 미량원소가 피부 표면의 활력을 증진시키는 피부 보호기능을 하기 때문에 탈모방지 및 발모에 효과적일 뿐만 아니라 인체에 균형을 유지케 하여 탈모의 원인을 치유케하는 작용을 하고, 심층수(선도액)를 취하여 -4 ∼ 0℃의 온도를 유지하면서 1 ∼ 2일간 정치하여 침전물을 제거한 후에 여과하는 방법으로 정제한 것을 사용한다.It is preferable to use a depth of 600m deep water and 1400m deep water, but it is possible to use both deep water above 600m deep and various minerals and trace elements contained in the depth water (leading liquid) enhance the skin surface vitality. It is effective in preventing hair loss and hair growth because it functions as a protective function, and maintains balance in the human body to heal the cause of hair loss, and takes in deep water (freshening liquid) while maintaining a temperature of -4 to 0 ° C. What is refine | purified by the method of filtering after leaving still for 2 days and removing a deposit is used.
심층수(선도액)의 사용량은 60 ∼ 74.5중량%가 바람직하며, 사용량이 60중량% 미만일 경우에는 탈모방지 및 발모의 효과가 만족스럽지 못하고, 74.5중량%를 초과할 경우에는 건강보조식품으로서의 효능이 저하되는 단점이 있다.The amount of deep water is preferably 60 to 74.5% by weight, and when the amount is less than 60% by weight, the effects of hair loss prevention and hair growth are not satisfactory. There is a disadvantage of deterioration.
유기 게르마늄(Ge-132)은 순도와 안전도가 매우 중요하며 체내에서의 소화 흡수 또한 매우 중요하기 때문에 분말 형상인 것을 심층수(선도액)에 용해하여 사용하며, 분말의 상태가 순백색이고, 입자나 알갱이 같은 것이 없이 밀가루처럼 고우며, 분말의 상태가 덩어리처럼 뭉친 것이 없고, 불순물이 섞여 있지 않은 것을 사용하여야 하며, 60 ∼ 80℃의 물(증류수면 더 정확함) 50cc에 유기게르마늄 분말 20mg을 넣고 교반시 물에 완전히 용해되고, 용해후 오랜 시간이 지나도 침전물(불순물)이 생기지 않아야 하며, 물에 완전히 녹은 후에는 물이 크리스탈처럼 보통의 물보다 더 맑고 투명하게 되는 것을 선택하여 사용한다.Organic germanium (Ge-132) is very important for its purity and safety, and its digestion and absorption in the body is also very important. So, it is used by dissolving it in deep water (leading liquid), and the state of powder is pure white. No matter the same, flour is fine, powder is not agglomerated like agglomerate, and it should be used without any impurities.Add 20mg of organic germanium powder to 50cc of water at 60 ~ 80 ℃ (more accurate distillation surface) and stir. It is completely soluble in water, and no sediment (impurity) should be formed after a long time after dissolution. After being completely dissolved in water, the water is selected to be clearer and more transparent than ordinary water like crystal.
유기게르마늄이 함유하고 있는 산소는 세포안에서 발생기 산소로 방출되는데, 보통 산소는 통상적인 상태에서는 분자 O2의 형태로 존재하지만 다른 물질과 화합할 때는 산소원자 O의 형태가 되며, 유기게르마늄은 발생기 산소를 빈사직전의 세포에 방출시켜 세포를 부활시키므로서 대사활동이라는 세포내 화학반응을 활성화시키게 되고, 세포는 본래의 기능을 되찾아 싱싱하게 작용하게 되며, 결과적으로 온몸의 컨디션이 호전되어 탈모의 병원이 제거되는 것이다.The oxygen contained in organo germanium is released into the generator oxygen in the cell. Normally, oxygen exists in the form of molecule O 2 in a normal state, but when combined with other substances, it becomes in the form of oxygen atom O, and organo germanium is generator oxygen. It releases to the cells just before dying and activates the intracellular chemical reaction called metabolic activity, and the cells regain their original function and act freshly. As a result, the condition of the whole body improves and the hospital of hair loss To be removed.
산의 바탕은 산소가 아니고 수소, 보다 정확하게 말하면 수소이온이고, 수소이온은 체내에서 쓸모가 전혀 없는 가스에 불과하지만 그것이 정도 이상으로 축적되면 체질이 산성화되었다고 하며, 컨디션을 무너뜨리는 계기가 되는 데, 이 불필요한 가스를 청소하는데 산소가 필요하며, 산소는 필요없는 수소이온과 결합하여 중성인 물이 되어 몸밖으로 배설되는데 유기게르마늄은 그것을 위한 산소를 공급하는 작용을 하며, 수은이나 카드뮴같은 유해한 중금속을 동반해서 체외로 배설시켜 주는 역할을 한다.The base of the acid is not oxygen, but hydrogen, more precisely hydrogen ions, and hydrogen ions are nothing but useful gases in the body, but when they accumulate more than that, the constitution is said to be acidified. Oxygen is needed to clean up this unnecessary gas, and oxygen combines with hydrogen ions, which are not needed, to form neutral water and be excreted out of the body. Organic germanium acts to supply oxygen for it, accompanied by harmful heavy metals such as mercury and cadmium. It acts to excrete outside the body.
본 발명에서는 버섯, 고려인삼, 밤, 구기자 열매 등과 같이 게르마늄이 고단위로 함유되어 있는 식용 가능한 식물로부터 분리한 것으로, 마늘, 컴프리, 알로에, 표고버섯같은 버섯류도 유기 게르마늄(Ge-132)원으로 사용될 수 있으며, "카르복시 에틸 게르마늄 32산화물"(분자식 : (GeCH2CH2COOH)2O3)이 특히 효과적이다.In the present invention, it is isolated from edible plants containing germanium in a high unit such as mushrooms, Korean ginseng, chestnuts, goji berries, etc., mushrooms such as garlic, comfrey, aloe, shiitake mushrooms can also be used as a source of organic germanium (Ge-132) And "carboxy ethyl germanium 32 oxide" (molecular formula: (GeCH 2 CH 2 COOH) 2 O 3 ) is particularly effective.
유기 게르마늄(Ge-132)의 사용량은 0.5 ∼ 15중량%가 바람직하며, 사용량이 0.5중량% 미만일 경우에는 유기 게르마늄(Ge-132)의 효과 발현이 미약한 단점이 있고, 사용량이 15중량%를 초과할 경우에는 첨가 상승효과가 미약하여 경제적이지 못한 단점이 있다.The amount of organic germanium (Ge-132) is preferably 0.5 to 15% by weight, and when the amount is less than 0.5% by weight, the effect of organic germanium (Ge-132) is weakly expressed. If exceeded, there is a disadvantage in that the synergistic effect of addition is weak and not economical.
한편, 한약재는 탈모방지 및 발모에 효능이 있는 것으로 알려져 있는 것들을 사용하되, 상호 효능이 상승 작용을 하는 것들을 사용하며, 한약재를 열수 추출하여 정치한 다음, 여과한 것이 효과적이고, 한약재의 사용량은 25 ∼ 39.5중량%가 바람직하며, 사용량이 25중량% 미만일 경우에는 건강 보조 식품으로서의 효능 발현이 미약한 단점이 있고, 39.5중량%를 초과할 경우에는 심층수(선도액)와 유기 게르마늄(Ge-132)의 사용량이 상대적으로 감소되어 탈모방지 및 발모의 효과가 미약한 단점이 있다.On the other hand, herbal medicines are known to be effective in preventing hair loss and hair growth, but using synergistic synergistic ones. ~ 39.5% by weight is preferred, when the amount of use is less than 25% by weight has a weak disadvantage in expressing the efficacy as a dietary supplement, when it exceeds 39.5% by weight deep water (leading solution) and organic germanium (Ge-132) Since the amount of is relatively reduced, there are disadvantages in that the effects of hair loss prevention and hair growth are weak.
다음의 실시예는 본 발명을 좀 더 상세히 설명하는 것이지만, 본 발명의 범주를 한정하는 것은 아니다.The following examples illustrate the invention in more detail, but do not limit the scope of the invention.
실시예 1Example 1
해저 600m의 심층수와 1400m의 심층수를 취하여 -4 ∼ 0℃의 온도를 유지하면서 1일간 정치하여 침전물을 제거한 후에 여과하는 방법으로 정제한 다음, 해저 600m의 심층수와 1400m의 심층수를 1 : 1의 비율로 혼합한다.Take 600m deep water and 1400m deep water and leave it for 1 day while maintaining the temperature of -4 ~ 0 ℃, remove the precipitate, and then purify by filtering. Then, 600m deep water and 1400m deep water is 1: 1 ratio. Mix with.
별도로 생지황 15g, 당귀 9g, 사인 6g, 숙지황 15g, 백작 12g, 쌍심자 15g, 복신 15g, 목과 9g 및 황정 15g을 열수 1110g에 투입하여 6시간 동안 열수 추출한 다음, 실온으로 냉각하고 1일간 정치한 후, 침전물을 제거하여 10% 짜리 한약재 추출물을 준비하였다.Separately, 15g of raw Sulfur, Angelica 9g, 6g, Sukjihwang 15g, Earl 12g, double ginseng 15g, Fuxin 15g, neck and 9g, and 15g of Hwangjeong were put into 1110g of hot water, and extracted with hot water for 6 hours, and then cooled to room temperature and allowed to stand for 1 day. , The precipitate was removed to prepare a 10% herbal extract.
그 다음에 상기 심층수(선도액) 혼합물 68중량%, 상기 한약재 추출물 30중량%와 식물성 카르복시 에틸 게르마늄 32산화물 2중량%를 혼합하고 교반하여 식물성 카르복시 에틸 게르마늄 32산화물이 완전히 용해되고, 각각의 성분들이 균질하게 혼합되도록 하여 본 발명의 건강보조식품을 제조하였다.Then, 68% by weight of the deep water mixture (priming liquid), 30% by weight of the herbal extract and 2% by weight of the vegetable carboxy ethyl germanium 32 oxide were mixed and stirred to completely dissolve the vegetable carboxy ethyl germanium 32 oxide. It was made to be homogeneously mixed to prepare a health supplement of the present invention.
실시예 2 ∼ 실시예 8Example 2-Example 8
사용된 한약재의 종류와 양이 표 2와 같이 변경된 것을 제외하고는 실시예 1과 동일하게 행하여 건강보조식품을 제조하였다.The health supplement was prepared in the same manner as in Example 1 except that the type and amount of the herbal medicines used were changed as shown in Table 2.
[표 2]TABLE 2
실험예 1Experimental Example 1
본 발명에 따른 건강보조식품의 인체에 대한 무독성을 입증하기 위하여 마우스를 대상으로 급성독성시험을 실시하였다.In order to prove the non-toxicity of the health food according to the present invention to the human body, an acute toxicity test was conducted in mice.
[급성독성시험][Acute Toxicity Test]
(1) 재료 및 방법(1) materials and methods
가) 실험동물A) Experimental animal
1) 종(계통) : ICR계 마우스(ICR mouse)1) Species: ICR mouse
2) 성별 및 입수시 주령 : 수컷 4주령2) Gender and age at acquisition: Male 4 weeks
3) 선택이유 : 본 실험에 사용된 ICR계 마우스는 전세계적으로 독성시험에 널리 사용되어 왔기 때문에 생리, 해부 및 독성학적 기초자료가 풍부하여 그 결과를 비교하기가 유리하고 또한 실험동물의 구입 및 사용이 편리하여 선택하였다.3) Reason for selection: Since the ICR mice used in this experiment have been widely used in toxicology tests all over the world, it is rich in basic physiological, anatomical and toxicological data, so it is advantageous to compare the results. Selected for ease of use.
4) 공급원 : 대륙시험동물4) Source: Continental Test Animal
5) 검역 및 순화기간 : 실험실에 순화시키는 기간을 약 1주일 두었으며, 그 기간중 일반증상을 관찰하여 건강한 동물만을시험에 사용하였다.5) Quarantine and Purification Period: The laboratory was allowed to purify for about 1 week. During the period, general symptoms were observed and healthy animals were used for the test.
6) 정맥주사시 체중범위 및 주령 : 20± 3g, 5주령6) Body weight range and age at intravenous injection: 20 ± 3g, 5 weeks
7) 사용동물수 : 100마리(예비시험 포함)7) Number of animals: 100 (including preliminary test)
8) 군 분리 및 동물시별 : 시험에 사용된 건강한 동물의 체중을 측정하여 각 군의 평균체중이 거의 일치하도록 군 분리를하였고, 개체식별은 피모색소(피크린산) 마킹법과 사육상자별 TAG 표시법을 이용하였다.8) Group Separation and Animal Time: The weights of healthy animals used for the test were divided into groups so that the average weight of each group was almost identical. The individual identification was performed by the method of marking pigmented pigment (picrinic acid) and TAG by breeding box. Was used.
나) 동물실B) animal room
1) 온, 습도범위 : 온도 22± 2℃, 상대습도 53± 2%1) Temperature and humidity range: temperature 22 ± 2 ℃, relative humidity 53 ± 2%
2) 명암 사이클 : 형광등조명(09:00 점등~18:00 소등)2) Contrast cycle: Fluorescent lighting (09:00 to 18:00 off)
3) 조도 : 150~300Lux3) Roughness: 150 ~ 300Lux
4) 사육상자의 종류 : 순화, 검역, 투여 및 관찰기간 중 마우스용 플리카보네이트(polycarbonate)케이지(대종기계제작)4) Types of breeding box: Polycarbonate cage for mouse during purifying, quarantine, administration and observation period (manufactured by Daejong Machinery)
5) 사육상자당 동물수 : 순화, 검역기간 -5마리5) Number of animals per breeding box: Purified, quarantine period-5
투여기간-5마리Dosing period-5
다) 사료C) feed
1) 종류 : 실험동물용 고형사료1) Type: Solid feed for laboratory animals
2) 공급원 : 삼양유지사료주식회사2) Source: Samyang Oil Feed Co., Ltd.
라) 음수D) negative
1) 종류 : 여과된 수도수1) Type: filtered tap water
마) 시험물질E) test substance
1) 시료 : 상기 실시예 1에서 제조된 조성물(1000배 희석액)1) Sample: The composition prepared in Example 1 (1000-fold dilution)
공시험액(음성대조군)Blank test amount (negative control)
바) 투여방법F) Method of administration
1) 투여경로 : 경구투여(Oral)1) Route of administration: Oral administration (Oral)
2) 투여회수 및 투여기간 : 1회투여2) Number of administration and period of administration: 1 administration
3) 투여부위 및 투여법 : 마우스에 경구투여하였다.3) Administration site and administration method: The mice were orally administered.
4) 투여시각 : 10:00~12:004) Administration time: 10: 00 ~ 12: 00
5) 투여량 : 투여직전에 체중을 기준으로 하여 50ml/kg를 투여하였다.5) Dosage: 50ml / kg was administered immediately based on body weight.
(2) 시험방법(2) Test method
가) 국립보건원 독성시험에 따라 실시하였다.A) It was conducted in accordance with the National Institutes of Health toxicity test.
나) 임상증상관찰 : 전 동물에 대하여 매일 실시하였다.B) Clinical symptoms observation: All animals were conducted daily.
투여 후 6시간은 매시간 관찰하여 그후 5일간 1일 1회 운동성, 외관 및 자율신경증상을 주의 깊게 관찰하였다.Six hours after the administration was observed every hour, and carefully observed the mobility, appearance and autonomic symptoms once daily for 5 days thereafter.
(3) 시험결과(3) Test result
[표 3]TABLE 3
급성독성시험결과Acute Toxicity Test Results
실험예 2Experimental Example 2
시험 대상자의 선정 및 효능실험의 진행Selection of test subjects and progress of efficacy test
자연 탈모자로서 1 ∼ 10년간 탈모가 진행된 20 ∼ 50세의 실험 대상자 총 50명을 선정하여 실험군(Ⅰ)로, 원형 탈모자로서 20 ∼ 50세의 실험 대상자 총 25명을 선정하여 실험군(Ⅱ)로, 모발 탈색자로서 30 ∼ 50세의 실험대상자 15명을 선정하여 실험군(Ⅲ)으로 하였다.A total of 50 subjects of 20 to 50 years of hair loss who had undergone hair loss for 1 to 10 years as natural hair loss were selected as the experimental group (I), and a total of 25 subjects of 20 to 50 years as circular hair loss were selected. ), 15 subjects aged 30 to 50 as hair bleachers were selected as the experimental group (III).
각각의 실험군에 대하여 실시예 1에서 제조된 건강보조식품을 3개월간 하루 3회, 식후 2시간 후에 50ml 씩 섭취하도록 하고 다음과 같은 관찰을 실험 직전 및 종료 직후에 하여 기록하였다.For each experimental group, the dietary supplement prepared in Example 1 was ingested 50 ml three times a day for three months and two hours after a meal, and the following observations were recorded immediately before and immediately after the end of the experiment.
(1) 발모 갯수의 관찰 : 각각의 실험군의 실험 대상자의 실험 시작 직전의 관찰부위(두피 지름 2.54 cm의 원)를 정확히 정해두고 실험 종료 후와 전의 머리카락의 숫자를 기록하고 그 차의 평균치를 계산하고 그 결과를 하기 표 4에 나타내었다.(1) Observation of the number of hair growth: Accurately determine the observation area (circle with a scalp diameter of 2.54 cm) just before the start of the experiment of each subject, record the number of hairs before and after the experiment and calculate the average of the difference The results are shown in Table 4 below.
(2) 연구원들에 의한 직접 관찰 : 연구원들이 직접 두피의 머리카락을 관찰하고 발모 정도 및 탈색 개선 정도에 대한 관찰결과를 표 5에 개선율%로 나타내었다. 개선율%는 실험전 상태 0%, 완전회복 100%를 기준으로 하여 평가하였고, 그 결과는 하기 표 5에 나타내었다.(2) Direct observation by the researchers: The researchers directly observed the hair of the scalp and the observation results on the degree of hair growth and the degree of depigmentation are shown in Table 5 as a percentage of improvement. % Improvement was evaluated based on the pre-experimental state 0%, 100% complete recovery, the results are shown in Table 5 below.
(3) 자가평가 : 실험대상자 본인에게 다음과 같은 질문을 하였다. '머리 상태가 개선되었습니까?' 그 답은 '예' 와 '아니오' 로 하였으며, '예' 에 대한 비율을 하기 표 6에 나타내었다.(3) Self-evaluation: The subjects were asked the following questions. "Is your hair improved?" The answer was 'yes' and 'no', and the ratio for 'yes' is shown in Table 6 below.
[표 4]TABLE 4
[표 5]TABLE 5
[표 6]TABLE 6
머리 상태가 개선되었습니까?에 대한 답변Did you improve your hair?
상기 결과로부터 알 수 있는 바와 같이,탈모증상이 1 ∼ 10년 진행된 사람들의 90% 정도가 회복되었으며, 원형탈모의 경우 1개월 정도 복용하면 현저하게 머리털이 자라남을 확인할 수 있었다.As can be seen from the above results, about 90% of people with hair loss symptoms that were advanced for 1 to 10 years were recovered, and in the case of alopecia areata, hair growth was remarkably increased when taken for about 1 month.
상술한 바와 같이 본 발명에서는 해저 600m의 심층수와 1400m의 심층수를 정제하여 적정한 비율로 혼합한 정제된 심층수(선도액) 60 ∼ 74 5중량%, 생지황, 당귀, 사인, 수지황, 백작, 쌍심자, 복신, 목과, 황정, 하수오, 토사자, 보골지, 구기자, 우슬, 대사석, 죽엽, 감초, 수지, 생황기, 명천마, 동충하초, 여정자, 육종용, 복령, 도인, 당삼, 파극천, 두충, 산약, 녹각고, 소희향, 수오, 측백엽, 공쇄보, 대추, 천동, 맥동, 원지, 백자인, 오미자, 현삼, 강귀, 길경, 사삼, 흑대두, 고삼, 백선피, 백출, 방풍, 진피 등으로 구성되는 군으로부터 선택된 적어도 8종 이상의 한약재 추출물 25 ∼ 39.5중량% 및 유기 게르마늄(Ge-132) 0.5 ∼ 15중량%로 구성되어지되 정제된 심층수(선도액), 한약재 추출물 및 유기 게르마늄(Ge-132)을 혼합하여 본 발명의 건강보조식품을 얻고, 이를 복용하게 하므로서 탈모를 방지하고 발모을 용이하게 할 수 있었다.As described above, in the present invention, 60 to 74% by weight of purified deep water (leading liquid) 60 to 74% by weight of purified deep water of 600 m and deep water of 1400 m and mixed in an appropriate ratio, raw sulfur, Angelica, sine, resin sulfur, earl, bisimmon , Fuxin, tree, yellow flower, sewage, earth and sand, golgoji, wolfberry, dew, metabolic stone, bamboo leaf, licorice, resin, fresh yellow rice, Myeongcheon horse, Cordyceps sinensis, gourmet, breeding, fueryeong, doin, red ginseng, pageokcheon, tofu, pesticide Consisting of green tea, sohyanghyang, shou, cypress, jujube, jujube, cheondong, pulsation, original paper, white porcelain, schisandra, Hyunsam, gangwi, gilkyung, sasam, black soybean, red ginseng, baekseonpi, baekchul, windproof, dermis 25 to 39.5% by weight of at least 8 or more herbal extracts selected from the group and 0.5 to 15% by weight of organic germanium (Ge-132), and the purified deep water (freshness liquid), herbal medicine extract and organic germanium (Ge-132) Mixing to obtain a dietary supplement of the present invention, taking it Prevent hair loss and it hameuroseo balmoeul could be facilitated.
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KR100911868B1 (en) * | 2007-04-23 | 2009-08-11 | 박재경 | Composition of a hair care article for preventing a hair from falling out containing deep ocean water |
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