KR100286055B1 - 치주 질환의 진단 및 치료법 - Google Patents

치주 질환의 진단 및 치료법 Download PDF

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Publication number
KR100286055B1
KR100286055B1 KR1019980703117A KR19980703117A KR100286055B1 KR 100286055 B1 KR100286055 B1 KR 100286055B1 KR 1019980703117 A KR1019980703117 A KR 1019980703117A KR 19980703117 A KR19980703117 A KR 19980703117A KR 100286055 B1 KR100286055 B1 KR 100286055B1
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KR
South Korea
Prior art keywords
prtr
prtk
gingivalis
complex
antibody
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Expired - Fee Related
Application number
KR1019980703117A
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English (en)
Korean (ko)
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KR19990067167A (ko
Inventor
에릭 찰스 레이놀즈
피터 싱 보갈
나다 슬라케스키
Original Assignee
제이. 비. 포터, 웨인 알 존스
더 유니버시티 오브 멜버른
윌리암스 로드니 엔.
빅토리안 데어리 인더스트리 오소리티
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Application filed by 제이. 비. 포터, 웨인 알 존스, 더 유니버시티 오브 멜버른, 윌리암스 로드니 엔., 빅토리안 데어리 인더스트리 오소리티 filed Critical 제이. 비. 포터, 웨인 알 존스
Publication of KR19990067167A publication Critical patent/KR19990067167A/ko
Application granted granted Critical
Publication of KR100286055B1 publication Critical patent/KR100286055B1/ko
Assigned to 데어리 푸드 세이프티 빅토리아 reassignment 데어리 푸드 세이프티 빅토리아 권리의 전부이전등록 Assignors: 빅토리안 데어리 인더스트리 오소리티
Assigned to 더 유니버시티 오브 멜버른 reassignment 더 유니버시티 오브 멜버른 권리지분의 전부이전등록 Assignors: 데어리 푸드 세이프티 빅토리아
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6427—Chymotrypsins (3.4.21.1; 3.4.21.2); Trypsin (3.4.21.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56955—Bacteria involved in periodontal diseases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
KR1019980703117A 1995-10-30 1996-10-30 치주 질환의 진단 및 치료법 Expired - Fee Related KR100286055B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ATPN6275 1995-10-30
AUPN6275A AUPN627595A0 (en) 1995-10-30 1995-10-30 Diagnostics and treatments of periodontal disease
PCT/AU1996/000673 WO1997016542A1 (en) 1995-10-30 1996-10-30 Diagnostics and treatments of periodontal disease

Publications (2)

Publication Number Publication Date
KR19990067167A KR19990067167A (ko) 1999-08-16
KR100286055B1 true KR100286055B1 (ko) 2001-05-02

Family

ID=3790602

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019980703117A Expired - Fee Related KR100286055B1 (ko) 1995-10-30 1996-10-30 치주 질환의 진단 및 치료법

Country Status (13)

Country Link
US (3) US6511666B1 (https=)
EP (1) EP0858504B1 (https=)
JP (1) JP4117026B2 (https=)
KR (1) KR100286055B1 (https=)
AT (1) ATE312909T1 (https=)
AU (2) AUPN627595A0 (https=)
CA (1) CA2235224C (https=)
DE (1) DE69635582T2 (https=)
DK (1) DK0858504T3 (https=)
ES (1) ES2255082T3 (https=)
NZ (1) NZ320015A (https=)
WO (1) WO1997016542A1 (https=)
ZA (1) ZA969130B (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0735293U (ja) * 1993-12-10 1995-06-27 株式会社松島製作所 もやいの照明装置
US20030157637A1 (en) * 1998-09-15 2003-08-21 The University Of Melbourne Diagnostics and treatments of periodontal disease
AUPN627595A0 (en) * 1995-10-30 1995-11-23 University Of Melbourne, The Diagnostics and treatments of periodontal disease
AUPO652897A0 (en) * 1997-04-30 1997-05-29 University Of Melbourne, The Synthetic peptide constructs for the diagnosis and treatment of periodontitis
US8129500B2 (en) * 1997-12-10 2012-03-06 Csl Limited Porphyromonas gingivalis polypeptides and nucleotides
ES2377751T3 (es) * 1997-12-10 2012-03-30 Csl Limited Polipéptidos y polinucleótidos de Porfiromonas gingivalis
AUPP494798A0 (en) 1998-07-29 1998-08-20 Pacific Biolink Pty Limited Protective protein formulation
AUPP893999A0 (en) * 1999-03-01 1999-03-25 Csl Limited Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with porphyromonas gingivalis
AUPQ485999A0 (en) * 1999-12-24 2000-02-03 Csl Limited P. gingivalis antigenic composition
AUPQ718200A0 (en) 2000-04-28 2000-05-25 Csl Limited Porphyromonas gingivalis recombinant proteins and truncations
SE0400191D0 (sv) * 2004-01-30 2004-01-30 Tendera Ab A test kit for detecting periodontal disease
EP1799705A4 (en) * 2004-09-23 2008-11-05 Univ Melbourne Antigenic complex for the diagnosis and treatment of porphyromonas gingivalis infection
AU2005287884B2 (en) * 2004-09-23 2010-12-02 The University Of Melbourne Antigenic complex for the diagnosis and treatment of Porphyromonas gingivalis infection
AU2007204730B2 (en) 2006-01-10 2011-11-17 Colgate-Palmolive Company Methods of modulating cell surface receptors to prevent or reduce inflammation
CA2652957A1 (en) 2006-06-27 2008-01-03 Oral Health Australia Pty Ltd. Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease
US20100297179A1 (en) 2007-07-12 2010-11-25 Stuart Geoffrey Dashper Immunology Treatment for Biofilms
WO2009006699A1 (en) 2007-07-12 2009-01-15 Oral Health Australia Pty Ltd Biofilm treatment
DK2328914T3 (en) * 2008-08-29 2017-07-10 Oral Health Australia Pty Ltd Prevention, treatment and diagnosis of P. gingivalis infection
US8140041B2 (en) * 2009-08-27 2012-03-20 Mediatek Inc. Tunable capacitive device with linearization technique employed therein
MY162557A (en) 2010-02-26 2017-06-15 Oral Health Australia Pty Ltd Treatment or prevention of infection
SG11202003147XA (en) 2017-10-12 2020-05-28 Vaxcyte Inc Periodontitis vaccine and related compositions and method of use
CN111172177B (zh) 2019-07-30 2023-08-08 镇江市江澜绿洲生物技术有限公司 cra4S1基因及其编码的蛋白和应用
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830710A (en) 1988-09-08 1998-11-03 University Of Florida Cloned porphyromonas gingivalis genes and probes for the detection of periodontal disease
WO1995000110A1 (en) * 1993-06-28 1995-01-05 Lion Corporation Composition for oral cavity
US5523390A (en) * 1993-09-10 1996-06-04 University Of Georgia Research Foundation, Inc. Porphyromonas gingivalis arginine-specific proteinase
WO1995007286A1 (en) 1993-09-10 1995-03-16 University Of Georgia Research Foundation, Inc. Porphyromonas gingivalis arginine-specific proteinase coding sequences
US5475097A (en) 1993-10-21 1995-12-12 University Of Georgia Research Foundation, Inc. Lysine-specific Porphyromonas gingivalis proteinase
AUPN627595A0 (en) * 1995-10-30 1995-11-23 University Of Melbourne, The Diagnostics and treatments of periodontal disease
AUPO652897A0 (en) * 1997-04-30 1997-05-29 University Of Melbourne, The Synthetic peptide constructs for the diagnosis and treatment of periodontitis

Also Published As

Publication number Publication date
EP0858504A1 (en) 1998-08-19
AU7267396A (en) 1997-05-22
JP2000510817A (ja) 2000-08-22
NZ320015A (en) 1999-02-25
ATE312909T1 (de) 2005-12-15
US20070189982A1 (en) 2007-08-16
US6511666B1 (en) 2003-01-28
KR19990067167A (ko) 1999-08-16
JP4117026B2 (ja) 2008-07-09
AUPN627595A0 (en) 1995-11-23
DK0858504T3 (da) 2006-02-13
CA2235224C (en) 2011-11-29
CA2235224A1 (en) 1997-05-09
EP0858504B1 (en) 2005-12-14
AU715456B2 (en) 2000-02-03
US20110213129A1 (en) 2011-09-01
ZA969130B (en) 1997-06-24
EP0858504A4 (en) 2002-12-04
ES2255082T3 (es) 2006-06-16
WO1997016542A1 (en) 1997-05-09
DE69635582T2 (de) 2006-08-17
DE69635582D1 (de) 2006-01-19

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KR100527070B1 (ko) 치주염의진단및치료용포르피로모나스긴기발리스항원
US20030157637A1 (en) Diagnostics and treatments of periodontal disease
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