KR100277345B1 - Leather paper containing purgatory powder and its manufacturing method and uses - Google Patents

Abstract

An object of the present invention is to provide a leather paper containing the purgatory powder and a method and use of the same.

The present invention is sprayed to penetrate 10 ~ 30% by weight of the mixture of the particle size 100 ~ 1000 mesh jade powder with respect to the liquid adhesive into the tissue of the leather paper, it was naturally dried at room temperature for about 24 hours or more, the leather paper itself It has physical strength and mechanical strength, and when it is worn on the body made of leather products, the components generated from purgatory have excellent medical effects such as activation of cellular function, blood circulation and metabolism.

Description

Leather paper containing jade powder, its manufacturing method and use

The present invention relates to a leather paper containing nephrite powder and a method for manufacturing the same, and to a method of using the same, and in particular, the present invention relates to a hollow fiber brown rice fiber having a very thin fiber of amphibole feldspar (透 角閃石-陽 起 石) series. The fine powder of nephrite jade powder is contained in leather paper, which improves the physical strength and mechanical strength of the leather paper itself, and the components contained in the jadestone when wearing leather products made from it. , Fe, Mg) relates to leather paper containing jade powder which has an effective function for human health, and a manufacturing method and use thereof.

As is well known, jade is roughly divided into jadeite and nephrite, and jadeite is a lead masonry mineral belonging to the pyroxene family. Monoclinic system consisting of aluminum oxide and soda, hardness is a dense mass like crystal, light is black, cyan, green, transparent or translucent, usually jade Point to jadeite.

Purgatory is an inosilicates monolithic whiskey mineral, divided into purgatory and serpentine superbasic purgates in high-quality surrogate rocks, whose quality is fine. It is known that the structure, that is, the granules of caterpillar-positive stone sperm, is made of fastening and fiber, and the finer the fiber, the better the quality.

According to the German medical literature on the jade, Mauda Palmer Die Verborgene, "KRAFF der KRISTALLE und der EDELSTEINE", jadeite and purgatory are two different ores, which, like most gemstones, contain silicon and oxygen, While jadeite is formed of granular crystals, jadeite is composed of countless crystals such as fiber and hair and fine aggregates, and jadeite is particularly beneficial to the human body, unlike the sodium and aluminum components of jadeite. It has been recently reported to contain minerals, namely calcium, iron, and magnesium, which greatly affect the healing of illnesses caused by high blood pressure, diabetic circulatory disorders, heart disease and kidney disorders when worn with purgatory. In "Die Magie der Edelsteine" by Hedy Brusisu It is also mentioned.

On the other hand, in Dongbobogam, a classic of oriental medicine, if you put jade into Omiju and Jiyuju, it turns into water, and if you put it in Honjangsu, it's good to eat. When eaten in the same size as 大, the waste is discharged to the outside of the body, 1 oxol, 1 jijicho (地 楡 草), 1 bream (1 米), and 3 egret (白露) are mixed together and put in a copper bowl. If you build a temple, the oxol turns into water, which is called oxal (玉液), and is called Shinseonokjang (神仙 玉 漿), and is located in Sinnongboncho, Dangboncho, and herbalist trees. According to the jade powder to make the enlightenment and taking it not only has the effect of moisturizing the five intestines and completely discharging waste products in the body, but also removes the heat in the stomach, which is effective in the digestive system, Bronchial asthma and fever with a fever It's good for quenching thirst, and squirting clothes like sesame grains will make your body fly and lighten, lubricating your lungs, vocal cords, good for throat, nourishing your hair, It helps to nourish the function, especially to relieve stressful neurological disorders.In addition, it is good to eat white jade powder when the muscles are tense and the rats fly. Rubbing the skin for a day, such as scarring the main ingredients of purgatory has been known from early to show an excellent effect on the human body with little side effects.

However, despite the fact that purgatory is known to have excellent medical effects on the human body as described above, due to its scarcity, the purgatory was limited to being manufactured and used only as some jewelry for jewelry, such as necklaces, rings, and bracelets. It requires a lot of time, effort, and careful attention, and it is impossible to make it without skilled workers with long experience, and because it is expensive, it is economically disadvantageous, so there is almost no development as a general household product using purgatory. It is time for development to be desperately needed.

The present inventors pay attention to the beneficial life effects of human beings such as the ability to treat diseases of purgatory (headache, insomnia, indigestion, hand-to-hand, etc.), odor removal ability, and the ability to remove impurities (such as heavy metal removal) of objects, for many years. Completed after the research experiment, spraying a certain amount of a mixture of nephrite powder and liquid adhesive on the leather paper and adsorbing it into the tissue of the leather paper, which is used in clothing and personal care products. Purgatory that improves the tensile strength, elongation strength and abrasion resistance of the product itself as well as medical properties such as metabolism promoting ability, blood circulation activation ability, cell activation ability and odor removal ability by the action of far infrared rays absorbed by the human body It is to provide a leather containing powder and its manufacturing method and uses.

Another object of the present invention is to provide a maximal utilization of the purgatory powder by using the purgatory powder treated with residues or wastes derived from mining or jewelry processing.

In order to achieve the above object, the leather paper containing the purgatory powder of the present invention is characterized in that it contains leather paper and purgatory material penetrated into the leather paper.

In the above, the purgatory material is preferably mixed with the liquid adhesive 10 to 30% by weight of the briquette powder having a particle size of 100 to 1000 mesh.

The liquid adhesive is characterized in that any one selected from synthetic resins or synthetic rubber.

The purgatory powder is characterized by being in the following component ratios. <Semy QuanTitative Analysis (%)>

Silicon 34

Magnesium 10

Calcium 4.9

Iron 0.23

Aluminum 0.16

Copper 0.17

Cobalt 0.046

Manganese 0.14

Tin 0.024

Beryllium 0.00072

Is 0.0013

Titanium 0.0038

Nickel 0.0028

Chromium 0.0030

Miscellaneous 0

In addition, the manufacturing method of the leather paper containing the purgatory powder of the present invention comprises the step of mixing 10 to 30% by weight of the briquette powder having a particle size of 100 to 1000 mesh with respect to the liquid adhesive, and the mixed purge powder mixture adsorbed into the tissue of the leather paper Homogeneously spraying the jade powder mixed adhesive onto the back side of the leather paper, and naturally drying the leather paper sprayed with the jade powder mixed adhesive at room temperature for about 24 hours or more.

Use of the leather paper containing the purgatory powder of the present invention is to spray a 10 to 30% by weight mixture of the purifying powder with a particle size of 100 to 1000 mesh to the liquid adhesive to penetrate into the tissue of the leather, and then naturally dry it at room temperature for about 24 hours or more. It is characterized by making a product using the leather produced by the method of claim 5.

Products manufactured using the leather paper include garments such as pants, jumpers and coats, gloves such as golf gloves, briefcases such as briefcases, handbags, backpacks, golf bags, hats, golf shoes and horse riding. Shoes such as shoes, gentlemen's and ladies' shoes, military shoes, boots, furniture such as belts, chairs, sofas, beddings such as pillows and cushions, automobile seats, and other personal items It is characterized in that the leather goods.

The particle size of the jade powder used in the present invention is generally suitable for 100-350 mesh. However, when ductility needs to be increased, it is advantageous to use fine particles of about 350-1000 mesh, which are finer particles. If the grain size of the purgatory powder is larger than the above range, the surface roughness of the product becomes severe, which is not preferable.

In addition, the addition amount of the nephrite powder is suitable 10 to 30% by weight, if the addition amount is less than 10% by weight, it is not preferable because the effect of the nephrite addition can not be expected, the higher the addition amount of nephrite powder is improved inherent efficacy of the purgatory However, if the added amount is excessive, not only the properties of the raw materials, in particular, the ductility thereof may be deteriorated, but also the product price is increased due to the high price of the nephrite powder, so 30 wt% or less of the total weight of the resin raw material is appropriate. .

Leather products used in the manufacture of leather paper with jade powder added according to the present invention are mainly made of jewelry, bowls, sculptures, etc. from the jade gemstone, and the remaining residues are crushed and used economically in terms of cost reduction and expensive. It is also economically appreciated in that it is possible to obtain a variety of practical articles having peculiar properties of purgatory at a lower cost than products such as jade bowls. In addition, it can be seen that the leather of the present invention or leather products made using the same have higher effects on mechanical and physical properties, ie, heat resistance, tensile strength, and elongation strength, as compared to conventional products that do not contain jade.

1 is a crystal structure diagram of jadeite powder contained in the leather paper according to the present invention shown by a scanning electron microscope (SEM),

2 is a scanning electron micrograph (SEM) of jade water untreated silk according to the present invention,

3 is a scanning electron microscope (SEM) photograph of jade water treated silk of the leather according to the present invention,

Figure 4 is a graph showing the change in the activity of the test sphere (mouse) after drinking the jade water was carried out in the leather according to the present invention,

Figure 5 is a graph showing the results of observing the change in the total volume of the culture medium of digitalis lantana (Digitalis lanata) cells growing in the growth medium,

FIG. 6 is a graph showing the change in the volume of digitalis lantana (Digitalis lanata) cells,

7 is a graph showing changes in the biomass of cells,

8 is a graph showing the change in dry weight of cells,

9 is a graph showing the pH change of the digitalis lantana (Digitalis lanata) culture medium,

10 is a graph showing the pH change of the production medium after the addition of purgatory powder,

11 is a view showing the result of the state condition of the analyzer;

12 is a diagram showing an output of an analysis result.

The preferred embodiment of the leather paper containing the purgatory powder according to the present invention and its manufacturing method and use will be described in more detail.

10 to 30% by weight of the jade powder with a particle size of 100 to 1000 mesh is added to the synthetic resin or rubber-based liquid adhesive and mixed evenly using a general stirrer. The prepared natural or artificial leather is placed on the work surface with the back of the leather exposed to the surface and then spread evenly so that there is no wrinkle or fold. Subsequently, a liquid mixture of a liquid adhesive and a nephrite powder is filled into a sprayer (atomizer) widely used at home, and then sprayed evenly on the back of the flat unfolded leather paper. Although the spraying method is not specifically determined, spraying at an angle of about 45 ° at a distance of about 20 to 30 cm from the leather is preferable. The amount of spray of the jade powder mixture on the leather is good to spray to the leather paper.

The leather paper sprayed with the purgatory powder mixed adhesive is naturally dried at room temperature, and the drying time is preferably performed for approximately 24 hours. The dried leather is thus used for the production of the desired leather products through processes such as cutting and sewing.

Example 1

10% by weight of the nephrite powder obtained by pulverizing to 100 mesh particle size from the bulky nephrite is mixed with the synthetic resin-based liquid adhesion, and the liquid mixture is sprayed onto the prepared leather paper, followed by leather The paper was dried at room temperature for 24 hours to obtain leather paper containing jade powder, and the leather paper was used to manufacture various leather products such as clothes, shoes, and bags through cutting and sewing processes.

Example 2

Only the ratio of the particle size (500 mesh) of the nephrite powder to the liquid adhesion and the ratio of the nephrite powder (15% by weight) was different.

Example 3

Only the particle size (1000 mesh) of the nephrite powder and the ratio of the nephrite powder (30% by weight) with respect to the liquid adhesion was changed.

The manufactured leather itself is not only improved in physical strength and mechanical strength such as tensile strength, heat resistance and abrasion resistance, but also in the case of the leather products made using the same, far infrared rays absorbed into the living body during wavelength (approximately 10 microns or so) ), It can be seen that there is a medical effect (see experimental examples below).

Experimental Example 1

In order to find out how the garment made as a leather paper containing the purgatory powder manufactured by the above-described examples has a beneficial effect on the human body, it was carried out by the Daejeon University Oriental Medicine Hospital and the leather paper containing the purifying powder of the present invention. The results of comparing and measuring the wearing state of the leather garment product made using and the general leather garment product are shown in Tables 1 to 3 below.

<Test object: 45-year-old adult man> division General Leather Apparel Leather garment product of the present invention (state after 2 hours of wearing) Heart rate HR (SaO ₂ ) 81 BPM 76 BPM Blood pressure NIBP SYS 127 mmHg 128 mmHg MEAN (average) 107 mmHg 104 mmHg DIAS 80 mmHg 76 mmHg Oxygen Concentration (SaO ₂ ) 91% 93% Pulse rate 81 BPM 76 BPM

<Test object: Adult man 55 years old> division Plain leather apparel products Leather garment product of the present invention (state after 2 hours of wearing) Heart rate HR (SaO ₂ ) 81 BPM 85 BPM Blood pressure NIBP SYS 181mmHg 173 mmHg Average (MEAN) 142 mmHg 127 mmHg Diastolic (DIAS) 111mmHg 110 mmHg Oxygen Concentration (SaO ₂ ) 95% 95% Pulse rate 83 BPM 85 BPM

<Inspection subject: 64 years old adult woman> division Plain leather apparel products Leather garment product of the present invention (state after 2 hours of wearing) Heart rate HR (SaO ₂ ) 68 BPM 68 BPM Blood pressure NIBP SYS 185 mmHg 176 mmHg Average (MEAN) 117 mmHg 125 mmHg DIAS 104 mmHg 105 mmHg Oxygen Concentration (SaO ₂ ) 74% 96% Pulse rate 68 BPM 68 BPM

As shown in Tables 1 to 3 above, as a result of wearing the leather product containing the purgatory powder of the present invention, the oxygen concentration, that is, the amount of oxygen is generally increased as compared to the existing leather garments to promote the metabolism of the human body. , It was found that there is an excellent effect to smooth blood circulation.

Experimental Example 2

In clinical trials using medical mattresses made of leather containing purgatory powder according to the present invention, 88% of clinical trial patients were found to be effective.

◎ Criteria and selection method of examinee

Twenty-five patients were selected as clinical trial subjects who were diagnosed or diagnosed with symptoms such as headache, insomnia, Hyun-hoon, anxiety, chest pain, and numbness of hands and feet.

◎ Observation Event and Inspection Method

The patient's condition and physical changes were observed after using it for a certain period of time (10 or more) for patients undergoing inpatient treatment for headache, insomnia, dizziness, anxiety, chest pain, and numbness of hands and feet.

◎ Evaluation criteria and evaluation methods

end. Evaluation Criteria: Based on the initial status of observational items.

I. Evaluation method: The following method was used.

order division evaluation(%) One If the effect is small or no Less than 70% 2 When it works More than 70% 3 When there is a significant effect 80% or more 4 When the effect is close to cure over 90

◎ Clinical Trial Result (Main Effect)

1. Relieve headaches and dizziness

2. Insomnia, recovery of anxiety symptoms

3. Improvement of numbness

4. Improvement of symptoms such as indigestion (based on clinical results)

Test results by the evaluation method is shown in Table 5 below.

Effect Determination Disease No effect Effective Considerable effect Cure effect system Less than 70% More than 70% 80% or more over 90 Headache 2 3 5 One 11 Blows 0 2 One One 4 Anxiety, chest pain One One One 2 5 Numbness 0 One One One 3 Indigestion 0 0 2 0 2 system 3 (12%) 7 (28%) 10 (40%) 5 (20%) 25 (100%)

In the present invention as described above, the results of experiments on the efficacy and effects on the living body of purgatory powder contained in leather paper were as shown in the following tables.

Lead Content Test sample Jade minutes Sample property White powder Job number Federal Institute of F.D.A.American Studies IW 091394-1 Way Atomic absorption analysis result Not detected

<Heavy Metals (Pb, etc.)> sample Jade powder Sample property White Job number Federal IW 080894-4 Way USP 23 result Not detected

<Inorganic elution test> sample Jade powder Sample property White Job number Federal IW 080894-4 Way As result As

100 g of the sample was extracted with 1 liter of water by autoclave treatment, and the extract liquid was analyzed.

Analyte Results (ppm) Detection limit (ppm) Arsenic (As) ND 0.05 Barium (Ba) ND 0.20 Cadmium (Cd) 0.007 0.005 Chlorine (Cl) ND One Chrome (Cr) ND 0.01 Copper (Cu) ND 0.05 Fe ND 0.10 Pb ND 0.05 Manganese (Mn) ND 0.02 Mercury (Hg) ND 0.0005 Nitrate (NO ₃ ) ND 0.1 Selenium (Se) ND 0.05 Silver (Ag) ND 0.01 Sulfate (SO ₄ ) 2 One Zinc (Zn) ND 0.01

(ND = concentration is below detection limit or not detected)

As shown in the above experimental results, purgatory powder used in the present invention was proved to be safe when used as tableware because no harmful lead, heavy metals and other toxic components were detected.

Experimental Example 3

In this experiment, the effects of purgatory used in the present invention on the growth development and the quality of silkworms were examined (see FIGS. 1, 2 and 3).

① Materials and Methods

1. Disclosed silkworm breed: Baekokjam

2. Breeding time: November-December

3. Breeding method: constant temperature and humidity, heraldic mulberry leaf meat

4. Number of Disclosures: Control-150 Repeats 2 Repeats

Treatment-130 Heads 2 Repeat

5. Treatment details: Control-Mulberry feed by distilled water spray

Treatment-Mulberry feed by spraying purgatory

Processing Period: From 2nd Stage Sleep

Breeding Results by Oxygen Treatment division repeat Treated Larvae 5th Infancy Total larvae Chrysalis percentage Work time Work time % Indices Control One 150 7 7 23 7 91.3 100 2 150 7 7 23 7 76.6 Average 150 7 7 23 7 84.0 Treatment group One 130 7 15 23 15 74.1 85 2 130 7 15 23 15 68.2 Average 130 7 15 23 15 71.2

division repeat High yield Cocoon weight Cocoon shell weight Cocoon shell percentage (kg / 10,000) Indices g Indices cg time % Indices Control One 17.9 100 2.08 100 43.0 100 20.7 100 2 15.0 1.96 39.0 19.9 Average 16.5 2.02 41.0 20.3 Treatment group One 16.2 93 2.14 106 44.0 109 20.6 102 2 14.6 2.14 45.0 21.0 Average 15.4 2.14 44.5 20.8

<Threading from cocoon with Oxygen Treatment> division Cocoon filament length (m) Cocoon filament weight (cg) Silk size (d) Specific cutting length (m) Specific Cutting Filament Weight (cg) Thread Pulling Ability (%) Control 1,222 33.7 2.48 3.47 23.4 69 Treatment group 1,283 36.3 2.55 1,005 28.5 78

division Percentage of unprocessed silk (%) Refinement (score) Adhesion (g / d) Elongation (%) Raw silk weight (kg) Control 19.68 95 3.80 3.47 2.75 Treatment group 16.96 96 3.93 1,005 2.61

Change in Larvae Weight due to Jade Treatment division Weight of larvae immediately away from the third slough Weight of larvae immediately away from the fourth slough 5 weights on the 3rd day Mature caterpillars Control 0.46 1.85 20.80 47.4 Treatment group 0.47 1.94 23.03 52.2

<Reduction effect of blood glucose by jade solution> Silkworm extract Blood sugar Reduction effect of blood glucose Injection with maltose '(A) Injection into silkworm extract (B) Reduction amount (C = A-B) efficiency Water treatment mg / 100ml mg / ml mg / ml% 64.0 ± 1.87 27.7 ± 1.70 36.3 56.7 Treated with jade solution 69.6 ± 1.62 20.7 ± 1.62 48.9 70.3

': Injection of Silkworm Extract Previous

result

The weight of larvae was heavier than the control of distilled water in the age of messenger, especially 0.48 g / kg.

2. The rate of fire was 71.2%, which was 15% lower than that of control, and 15.4g of 10,000 head was 7% lower than control.

3. The total weight of the necrosis was 2.14 g, 6% heavier than the control, and 44.5 g, 9% heavier. The silk ratio was 2% higher than the control.

4. Purgatory feeding showed better overall performance than control. In particular, the length of silk thread was long, the amount of silk was high, and the rate of hatchery was much higher than that of the control by about 9%.

5. In the sands, the nephrophylls showed slightly thicker fine grains, and showed higher ratios of strength, elongation, and yield than those of the control.

6. There was no significant difference in silk surface structure between control and treatment.

7. The crystal structure of the nephrite nephrite had a pointed rod structure.

Experimental Example 4

In this experiment, we observed changes in the activity of mice drinking jade flour drinking water added with jade jade used in the present invention. As shown in FIG. 4, the mice in the positive control group began to stabilize the central nerve from 5 minutes after drinking Uvabito (Note: Chinese name) medicine in the stabilization experiment, and gradually returned to normal after 30 minutes. Mice in the control group showed ups and downs in activity rates and declined overall. The activity rate of the drinking test group (mouse) of the drinking water of jade powder was similar to that of the normal control group, but the average value of the overall activity rate was not only higher than that of the control group but also significantly different from that of the control group. .

Experimental Example 5

In this experimental example, infrared experiments were performed on purgatory powder.

sample Jade minutes Sample property White method of inspection Perkin elmer 137 result As

<In IR spectrum>

Form: Tetrahydrofran Liquefied Thin Film

It appeared to match the pattern of polycarbonate resin and radiated electromagnetic waves with a wavelength of 6-52μ.

Experimental Example 6

In this Experimental Example, the chemical and biological oxygen requirements for the purgatory powder samples used in the present invention were performed as shown in Tables 15 and 16 below.

sample Jade minutes Sample property White Way Standard method result As

division Water (control) Jade addition 5-day BOD 224 mg / l 223 mg / l COD 115 mg / l 110 mg / l

Experimental Example 7

In this experimental example, the experiment on the effect of the purgatory powder used in the present invention for the experimental sphere (rabbit) was performed as shown in Table 17.

Primary eye irritation test sample Jade minutes Sample property Milky powder Way As result As

Method: US Federal Register Vol 43.No 163-1978.8.22 p37359

Experimental procedure: Place 0.1 ml of the extract on the inverted lower eyelid of one eye, and gently hold for 1 second before placing the upper and lower eyelids. The other eye is not treated and observed as a control example. The treated eyes of the six rabbits were left unwashed, and the eyes of the three rabbits were washed with running lukewarm water for one minute immediately after treatment. Prior to treatment with the sample, the eyes were examined in advance by fluorescence and only animals that did not show corneal damage were used for the test. Eye lesions were observed 24 hours, 48 hours, 72 hours, 7 days and 14 days after treatment. The results were shown in Table 18 below.

<Degree of eye lesion> rabbit time Corneal Opacity Corneal area Iris Price Conjunctival redness Conjunctival Chemosis Conjunctival secretion # 1 fine 24H 0 0 0 0 0 0 48H 0 0 0 0 0 0 72H 0 0 0 0 0 0 7D 0 0 0 0 0 0 score Corneal (0) Iris (0) Conjunctiva (0) # 2 fine 24H 0 0 0 0 0 0 48H 0 0 0 0 0 0 72H 0 0 0 0 0 0 7D 0 0 0 0 0 0 score Corneal (0) Iris (0) Conjunctiva (0) # 3 fine 24H 0 0 0 0 0 0 48H 0 0 0 0 0 0 72H 0 0 0 0 0 0 7D 0 0 0 0 0 0 score Corneal (0) Iris (0) Conjunctiva (0) # 4 fine 24H 0 0 0 0 0 0 48H 0 0 0 0 0 0 72H 0 0 0 0 0 0 7D 0 0 0 0 0 0 score Corneal (0) Iris (0) Conjunctiva (0) # 5 fine 24H 0 0 0 0 0 0 48H 0 0 0 0 0 0 72H 0 0 0 0 0 0 7D 0 0 0 0 0 0 score Corneal (0) Iris (0) Conjunctiva (0)

# 6 fine 24H 0 0 0 0 0 0 48H 0 0 0 0 0 0 72H 0 0 0 0 0 0 7D 0 0 0 0 0 0 score Corneal (0) Iris (0) Conjunctiva (0) # 7wash 24H 0 0 0 0 0 0 48H 0 0 0 0 0 0 72H 0 0 0 0 0 0 7D 0 0 0 0 0 0 score Corneal (0) Iris (0) Conjunctiva (0) # 8wash 24H 0 0 0 0 0 0 48H 0 0 0 0 0 0 72H 0 0 0 0 0 0 7D 0 0 0 0 0 0 score Corneal (0) Iris (0) Conjunctiva (0) # 9wash 24H 0 0 0 0 0 0 48H 0 0 0 0 0 0 72H 0 0 0 0 0 0 7D 0 0 0 0 0 0 score Corneal (0) Iris (0) Conjunctiva (0)

I. Cornea

(A) Opacity-Density (area for detoxification)

Normal-0

Scattered Diffusion Zones-Details of the iris are clearly visible-1

Translucent areas that are easily identified, slightly blurred details of the iris-2

Milky white area, details of the iris are not visible, pupil size is almost indistinguishable

Opaque, no iris visible-4

(B) corneal area

Normal-0

Less than 1/4, but not 0-1

More than 1/4, less than 1/2-2

1/2 or more, 3/4 or less-3

More than 3/4, less than total area-4

Score is A × B × 5, total max = 80

II. Iris

(A) value

Normal-0

Folded above normal, hyperemia, swelling, pericorneal congestion (these symptoms appear in any size, alone or in combination), the iris still responds to light (slow response is pronounced)-1

Not responding to light, bleeding, total destruction (one or both of these symptoms)-2

Score is A × 5, maximum possible total = 10

III. conjunctiva

(A) red tide (only related to the conjunctiva of the eyelid)

Normal-0

Blood vessels are surely reddened above normal-1

More diffuse, deeper magenta, individual vessels not easily distinguished-2

Spread red like beef-2

(B) chemosis

No Snooze-0

Random swelling phenomenon over normal (including eye blink membrane)-1

Clearly swollen with partial inversion of the eyelids-2

Eyelid half closed and swollen-3

Eyelid half to full closed and swollen-4

(C) secretion

Normal-0

Any phenomenon other than normal (not including small amounts observed at the tip of the inner eye of normal animals)-1

Secretions only on the eyelids and eyebrows adjacent to the eyelids-2

Significant area around the eyes-3

Score (A + B + C) × 2, total max = 20

CONCLUSIONS: This sample was determined to be free of eye irritation and, therefore, was found to be suitable for use in eye cosmetic products.

Primary skin irritation test sample Jade minutes Sample property White powder Way As result As

Method: US Federal Register Vol. 43, No. 163

CTFA (The Cosmetic, Toiletry and Fragrance Association, Washington, D.C.) Technical Guidelines

Experimental procedure: Patch testing was performed on the skin of the white rabbit and the original skin. The hair was cut short at the back and sides. Two areas, about 10 cm away, were selected as patch locations. One area is made of 4 small epidermal incisions in the patch area to remove the skin (two of which are perpendicular to the other and are "tic-tac-toe"). The patch is attached using a thin rubber band and adhesive tape Samples are introduced in each part in an amount of 0.5 ml (g) under the patch The body of the animal is wrapped with a rubberized cloth for 24 hours of exposure. After the patch was removed, the reaction at each site was evaluated based on the scores described below (see Table 20).

Evaluation of Skin Response

Erythema and crust formation

No erythema-0

Very weak erythema (recognizable barely)-1

Properly Identified Erythema-2

Moderate to severe erythema-3

Severe erythema (beat red) to slight crust formation (deep damage)-4

Edema

No edema-0

Very mild edema (recognizable barely)-1

Slight edema (it is obvious that the edges of the area are prominent)-2

Moderate edema (approximately 1 mm up)-3

rabbit 24 hours 72 hours Original skin Worn skin Original skin Worn skin ER ED ER ED ER ED ER ED #One 0 0 0 0 0 0 0 0 #2 0 0 0 0 0 0 0 0 # 3 0 0 0 0 0 0 0 0 #4 0 0 0 0 0 0 0 0 # 5 0 0 0 0 0 0 0 0 # 6 0 0 0 0 0 0 0 0

Conclusions: This sample was determined to have no skin irritation. It has therefore been found to be suitable for use in skin cosmetic products.

<Acute oral toxicity [(0.5 g) / 100 g body weight] experiment> sample Purgatory powder Sample property White powder Way As result Same as Table 22 below

rat gender Initial weight (g) Dosage (ml) Lag weight (g) Toxicity One F 207 1.0 219 none 2 F 211 1.1 226 none 3 F 215 1.1 225 none 4 F 208 1.0 217 none 5 F 200 1.0 213 none 6 M 227 1.1 235 none 7 M 216 1.1 224 none 8 M 205 1.0 218 none 9 M 210 1.1 224 none 10 M 212 1.1 221 none

Preparation of Samples: A portion of the sample was placed in sterile distilled water and boiled for 10 minutes to extract, and the extract was administered by intubation in an amount of 0.5 g per 100 g of body weight.

CONCLUSIONS: The sample meets the criteria for no oral toxicity.

Experimental Example 8

This experiment example is a process and results of the experiment performed by the Inha University bioinformatics system engineering laboratory to investigate the various effects of the purgatory powder used in the present invention on the living body. In this experiment, 70% of the constituent elements of the human body are water. Therefore, the impact of water on the water and the impact on the human body are investigated. Experiments on the effects were performed.

A. Hard water change

Experiment 1

100 ml of artificially-made hard water was transferred to each of the four flasks by 50 ml, and purgatory was placed on the bottom of two flasks for about 10 minutes.

To determine the change in hardness, a titration method using ethylene diamineacetic acid (hereinafter referred to as "EDTA" titer 2.9412) was used. 1 ml of a buffer solution of pH 10, EBT was used as an indicator.

The change in hardness was measured by the amount of EDTA until the moment when the color of the hard water was changed by EDTA. At this time, the color returned to its original state over time, but in this experiment, the measurement was made based on the changing moment.

<Result 1>

At 100ppm hard water, EDTA 1.70ml is required.

It takes 1.25ml of EDTA after purgatory test, so the hardness of 100.00ppm is lowered to 73.53ppm. That is, the hardness of 100.00 ppm was softened 26.47%.

Experiment 2

200 ml of 100ppm hard water made in the same manner as in Experiment 1 was transferred to a beaker to immerse the purgatory.

After about 30 minutes, the water in the beaker was divided into three flasks to measure the change in hardness. In this experiment, the hardness was measured by adding EDTA until the color of hard water did not change any more after the color of hard water changed by EDTA.

<Result 2>

Each 100ppm hard water before purgatory experiment

89.62 ppm

91.19ppm

89.62 ppm

Average 90.14ppm, thus 9.9% hardness decrease

Experiment 3

This experiment was conducted with tap water. Tap water was placed in a container and transferred to six flasks, and purgatory was placed at the bottom of three flasks, and hardness was measured after about 5 minutes.

<Result 3>

* Tap water without purgatory

97.48 ppm

97.48 ppm

97.48 ppm

Average 97.48 ppm

* Tap water after purgatory experiment

91.19ppm

91.19ppm

91.19ppm

Average 91.19ppm therefore, hardness decrease of 6.5%

I. Effect of Purgatory on the Proliferation of Digital Plant Suspensions of Digitalis lanata

Effects of Purgatory on the Growth of Digitalis lanata Cells in Growth Medium

FIG. 5 is a graph showing changes in culture medium volume of cells grown in growth medium for 11 days, and FIG. 6 is a graph showing changes in cell volume, in proportion to the increase of cells growing over time. As the depletion of and the evaporation of the medium occur, the volume change of the whole culture reflects these factors. In particular, humidity and temperature in the atmosphere are closely related to the evaporation of the medium, and such factors also affect the cell growth rate.

As shown in the figure, the use of purgatory shows that the volume of the total culture solution is slightly decreased compared to the control group which is not used. This is because the use of purgatory rather than the control group has a faster cell growth rate against the evaporation of the medium or the depletion of nutrients, and thus, it is possible to offset the rapid decrease of the depleted medium to some extent. This phenomenon is observed in the case of continuous use of purgatory from day 4 to day 11 after inoculation of cells as shown in Fig. 6 measuring the volume change of the sunk cells only increase the volume of the cell than the unused control group. This fact can be estimated. Therefore, the use of nephrite showed a faster cell growth rate than the control without the nephrite. These results can be said to be the result of delaying the decrease of the total volume than the control by offsetting the decrease in the total culture volume due to nutrient depletion and medium evaporation. In addition, the result of comparing the volume of the increased cell alone is also observed to show a tendency to gradually increase the cell volume after 4 days, it is thought that can support this result.

Cell proliferation and dry weight are the most common measures of cell proliferation. In general, the growth curve of all cells is represented by the S-shaped curve, which can be classified into four stages. Lag phase, which is a period of adaptation to the medium, in which there is no cell proliferation and no mass growth, and an exponential curve showing a steep slope due to a mass increase at a rapid proliferation rate after this period. phase), the stationary phase, which has a maximum growth to some extent, and the Chinese food is slowed down and shows no mass increase, and the cell ruptures due to the depletion of nutrients, the release of toxic components, and the saturation of cell density. It can be divided into a dead phase where the total cell volume or mass decreases due to the tendency to die.

7 and 8 are the results of measuring the cell biomass and dry weight.

7 follows the growth curve of these four stages. In the case of using jade, after 7 days, the growth rate was slightly higher than that of the control without jade, and the growth stopped until 10 days, unlike the control showing the decrease in cell biomass. have. This is remarkable in that cell growth is continued even when the concentration of nutrient is almost depleted and the concentration in the medium becomes zero compared with the change in the concentration of glucose, a nutrient that acts as the main metabolic substrate in the medium. It is common to show a tendency to stop the growth and decrease the growth rate at the point of depletion of the influenced ingredients, like the control without purgatory, but the effect of purgatory on cell growth is different from purgatory It is assumed that there is. This result is also shown in Figure 8 shows the cell growth proliferating at a higher rate than the control after 3 days, and from 9 days after, the same phenomenon as in FIG. As a result, cells grown near nephrite in the growth medium showed better effect on cell growth than the control group that did not. Digitalis lanata plant cells, which have a growth limit of about 10 days, are maintained in a stable state that does not cause necrosis of cells without exchanging with new medium even after 10 days when cultured with purgatory. Rather, it is expected that cell proliferation may be an advantageous method for optimizing cell growth and concentration in the production process for the production of useful substances.

② Effect of Purgatory on Changes in Medium pH

9 is a graph showing the pH change in the cell growth medium, Figure 10 is a graph showing the pH change of the production medium after the addition of purgatory powder.

Figure 9 is a measure of the change in the pH of the medium in the control medium with and without the purgatory in the growth medium. The control group shows a general tendency of pH in the medium applied to the plant cells, which gradually decreases over time and is maintained at a certain level. However, when using purgatory, it showed a similar pattern to the control group until day 7, and gradually increased. This phenomenon is extreme in the result of FIG. . The control group without added jade powder showed a consistent drop in pH, while the addition of jade powder showed a tendency to maintain the value to some extent. It is assumed that it acts as a cause.

③ Results of analysis of water quality for purgatory

FIG. 11 is a view showing the condition of the water analyzer containing the purgatory powder used in the present invention, and FIG.

The data from FIG. 11 and FIG. 12 is summarized in Table 23 to Table 26. Table 23 shows the analysis of each analysis item for Sample 1 after 48 hours of 20 g of nephrite mass in the solution. In Table 23, there is little change in each measurement item, and the effect of purgatory is hardly seen.

Table 24 shows the measured values for each analysis item in Sample 2 after 48 hours of placing 20 g of purgatory lumps outside the solution.

Table 26 also shows the measured values for each analysis item in Sample 4 after 48 hours after placing the purge powder outside of the solution. However, in the case of Sample 3, the data measured for each analysis item of the sample 48 hours passed after 20 g of purgatory powder was added to the solution is shown in Table 25. This change is as follows.

Cr, Pb, Ni, and Co, which are harmful to the human body, changed significantly after 48 hours. Cr was removed in the absence of purgatory powder, that is, 45.30 mg before the reaction was removed to 0 after 48 hours in the purifying powder, and Pb was also completely removed from 13.76 mg to zero. Ni decreased from 51.8 mg to 1.733 mg and Co also decreased from 52.69 mg to 11.94 mg. Mg, one of the necessary elements in the human body, increased from 48.36mg to 55.74mg.

The hydrogen ion concentration of distilled water was acidic to pH 3.5, but after the reaction, it was neutral to pH6.8, and the conductivity rapidly decreased. The adsorption force is physically large, about 3-4 mmol.q (equivalent) per gram.

Analytical results before and after the reaction in solution Purgatory lumps in the solution. (Sample 1): Purgall lump in solution (20 g) Item Before the reaction After reaction (48hr) Change pH 3.5 3.82 - Ni 51.8 mg 51.75mg - Co 52.69mg 52.54mg - Cr 45.30mg 43.88mg - Mg 48.36mg 48.59 mg - Pb 13.76 mg 13.90mg -

Results of analysis of purgatory lumps outside the solution. (Sample 2): lump of purgatory jade (20g) Item Before the reaction After reaction (48hr) Change pH 3.5 3.65 - Ni 51.8 mg 48.92mg - Co 52.69mg 49.83mg - Cr 45.30mg 41.23mg - Mg 48.36mg 47.97mg - Pb 13.76 mg 15.1mg -

Analysis result when adding purgatory powder to solution. (Sample 3): Purgatory powder in solution (20g) Item Before the reaction After reaction (48hr) Change pH 3.5 6.8 +3.3 Ni 51.8 mg 1.733 mg -50.06mg Co 52.69mg 11.94mg -40.75mg Cr 45.30mg 0mg -45.30mg Mg 48.36mg 55.74mg + 7.38mg Pb 13.76 mg 0mg -13.76 mg

Analysis result when purgatory powder was placed outside solution (Sample 4): Purgatory powder outside solution (20g) Item Before the reaction After reaction (48hr) Change pH 3.5 3.7 - Ni 51.8 mg 51.53 mg - Co 52.69mg 52.55mg - Cr 45.30mg 43.0mg - Mg 48.36mg 48.39mg - Pb 13.76 mg 14.29 g -

As described above, the digitalis lanata plant suspension cells cultured for one week with nephrite close showed proliferation of about 30% or more in the absence of purgatory. This is a rare proliferative result even in the various experiments performed for the proliferation effect on conventional Digigitalis lanata plant cells for high concentration culture. In addition, experiments on how purgatory water affects hard water showed that soft water softened hard water without contact with water. Particularly, in the component analysis experiments on water using distilled water, precipitation of nephrite was carried out. After 48 hours, in the component analysis, the pH was increased, the Ni and Co components were reduced, the Cr and Pb were removed, and the heavy metals were removed. An unusual phenomenon was observed that led to the phenomenon of.

As such, purgatory powder according to the present invention has not yet been clarified theoretically, but changes the hardness of water without contact with water, and also proliferates more than 30% of digitalis lant plant suspension cells. The removal of heavy metals such as reduction of Ni, Co, Cr, Pb and other harmful substances is believed to be due to the radiation effect of the wavelength of the purgatory powder and the ionic reaction by minerals contained in the nephrite. These facts will be proved by the efficacy shown in the product of the present invention described above, and also the above experimental results are products made of leather paper due to the characteristics of the purgatory powder contained in the leather paper according to the present invention, as well as the effect of purgatory When wearing it suggests that the effect of human health is enough.

According to the present invention as described above, according to the present invention as described above, by the jade powder contained in the leather paper, the leather paper itself has the effect of improving the physical strength and mechanical strength, in particular leather products made using the same When worn on the body, components from purgatory are effective in exerting excellent medical functions such as activating cellular functions, promoting blood circulation, and promoting metabolism.

Claims (7)

Leather paper; And Leather paper containing a purgatory powder containing a purgatory material infiltrated into the leather paper. According to claim 1, wherein the purgatory material is a leather paper containing a purgatory powder, characterized in that 10 to 30% by weight of the jade powder of 100 to 1000 mesh particle size mixed with the liquid adhesive. 3. The leather paper containing the jade powder according to claim 2, wherein the liquid adhesive is any one selected from synthetic resins or synthetic rubbers. 4. The leather paper according to claim 1, 2 or 3, wherein the nephrite powder is composed of the following component ratios. <Semy QuanTitative Analysis (%)> Silicon 34 Magnesium 10 Calcium 4.9 Iron 0.23 Aluminum 0.16 Copper 0.17 Cobalt 0.046 Manganese 0.14 Tin 0.024 Beryllium 0.00072 Is 0.0013 Titanium 0.0038 Nickel 0.0028 Chromium 0.0030 Miscellaneous 0 Mixing 10 to 30% by weight of the jade powder having a particle size of 100 to 1000 mesh with respect to the liquid adhesive; Homogeneously spraying the jade powder mixed adhesive onto the back side of the leather so that the jade powder mixed adhesive penetrates into and adsorbs into the tissue of the leather paper; And Method of producing a leather paper impregnated with jade powder comprising the step of naturally drying the leather paper sprayed with the jade powder mixed adhesive at room temperature for about 24 hours or more. Leather using a leather paper according to the method of claim 5, after spraying a 10 to 30% by weight mixture of jade powder with a particle size of 100 to 1000 mesh with respect to the liquid adhesive to penetrate into the tissue of the leather paper, and drying at room temperature for at least 24 hours. product. The method of claim 6, wherein the leather article is a garment, bag, shoes, belts, gloves, bedding, furniture, sheets and leather articles, characterized in that the use of the purpse-containing leather paper.