KR0178543B1 - N,n'-이치환된 구아니딘과 흥분유발 아미노산 길항제로서 그 사용방법 - Google Patents

N,n'-이치환된 구아니딘과 흥분유발 아미노산 길항제로서 그 사용방법 Download PDF

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Publication number
KR0178543B1
KR0178543B1 KR1019920702121A KR920702121A KR0178543B1 KR 0178543 B1 KR0178543 B1 KR 0178543B1 KR 1019920702121 A KR1019920702121 A KR 1019920702121A KR 920702121 A KR920702121 A KR 920702121A KR 0178543 B1 KR0178543 B1 KR 0178543B1
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KR
South Korea
Prior art keywords
guanidine
isopropylphenyl
ethylphenyl
naphthyl
iodinephenyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1019920702121A
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English (en)
Korean (ko)
Inventor
에카드 웨버
존 에프. 더블유. 키이나
Original Assignee
멜린다 더불유. 그리어
스테이트 오브 오리건 액팅 바이 앤드 쓰루 더 오리건 스테이트 보오드 오브 하이어 에쥬케이숀 액팅 포 앤드 온 비핼프 오브 더 오리건 헬쓰 사이언스 유니버시티 포트랜드 오리건 앤드 더 유니버시티 오브 오리건 유젠 오리건
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Application filed by 멜린다 더불유. 그리어, 스테이트 오브 오리건 액팅 바이 앤드 쓰루 더 오리건 스테이트 보오드 오브 하이어 에쥬케이숀 액팅 포 앤드 온 비핼프 오브 더 오리건 헬쓰 사이언스 유니버시티 포트랜드 오리건 앤드 더 유니버시티 오브 오리건 유젠 오리건 filed Critical 멜린다 더불유. 그리어
Application granted granted Critical
Publication of KR0178543B1 publication Critical patent/KR0178543B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019920702121A 1990-03-02 1991-03-04 N,n'-이치환된 구아니딘과 흥분유발 아미노산 길항제로서 그 사용방법 Expired - Fee Related KR0178543B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US487,033 1990-03-02
US07/487,033 US5093525A (en) 1986-07-10 1990-03-02 N,N'-disubstituted guanidines and their use as excitatory amino acid antagonists
PCT/US1991/001448 WO1991013056A1 (en) 1990-03-02 1991-03-04 N,n'-disubstituted guanidines and their use as excitatory amino acid antagonists

Publications (1)

Publication Number Publication Date
KR0178543B1 true KR0178543B1 (ko) 1999-05-15

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KR1019920702121A Expired - Fee Related KR0178543B1 (ko) 1990-03-02 1991-03-04 N,n'-이치환된 구아니딘과 흥분유발 아미노산 길항제로서 그 사용방법

Country Status (7)

Country Link
US (1) US5093525A (enExample)
EP (1) EP0516748A1 (enExample)
JP (1) JPH05509077A (enExample)
KR (1) KR0178543B1 (enExample)
AU (1) AU652555B2 (enExample)
CA (1) CA2077258A1 (enExample)
WO (1) WO1991013056A1 (enExample)

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Also Published As

Publication number Publication date
AU7484591A (en) 1991-09-18
AU652555B2 (en) 1994-09-01
EP0516748A1 (en) 1992-12-09
EP0516748A4 (enExample) 1994-04-13
US5093525A (en) 1992-03-03
JPH05509077A (ja) 1993-12-16
WO1991013056A1 (en) 1991-09-05
CA2077258A1 (en) 1991-09-03

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