JPWO2024090521A5 - - Google Patents
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- Publication number
- JPWO2024090521A5 JPWO2024090521A5 JP2024553135A JP2024553135A JPWO2024090521A5 JP WO2024090521 A5 JPWO2024090521 A5 JP WO2024090521A5 JP 2024553135 A JP2024553135 A JP 2024553135A JP 2024553135 A JP2024553135 A JP 2024553135A JP WO2024090521 A5 JPWO2024090521 A5 JP WO2024090521A5
- Authority
- JP
- Japan
- Prior art keywords
- pharma
- ceutically acceptable
- pharmaceutical composition
- group
- rar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000002148 esters Chemical class 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 229940096885 Retinoic acid receptor agonist Drugs 0.000 claims 3
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 claims 3
- FOIVPCKZDPCJJY-JQIJEIRASA-N arotinoid acid Chemical compound C=1C=C(C(CCC2(C)C)(C)C)C2=CC=1C(/C)=C/C1=CC=C(C(O)=O)C=C1 FOIVPCKZDPCJJY-JQIJEIRASA-N 0.000 claims 3
- 229930002330 retinoic acid Natural products 0.000 claims 3
- 208000010061 Autosomal Dominant Polycystic Kidney Diseases 0.000 claims 2
- 208000022185 autosomal dominant polycystic kidney disease Diseases 0.000 claims 2
- 102000003702 retinoic acid receptors Human genes 0.000 claims 2
- 108090000064 retinoic acid receptors Proteins 0.000 claims 2
- PNAWUIKCVQSLFG-UHFFFAOYSA-N 4-[(4-chloro-3-hydroxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]-2,6-difluorobenzoic acid Chemical compound C1=C2C(C)(C)CCC(C)(C)C2=C(Cl)C(O)=C1C(=O)NC1=CC(F)=C(C(O)=O)C(F)=C1 PNAWUIKCVQSLFG-UHFFFAOYSA-N 0.000 claims 1
- -1 AM80 Chemical compound 0.000 claims 1
- 239000000556 agonist Substances 0.000 claims 1
- HQMNCQVAMBCHCO-DJRRULDNSA-N etretinate Chemical compound CCOC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C=C(OC)C(C)=C1C HQMNCQVAMBCHCO-DJRRULDNSA-N 0.000 claims 1
- 229960002199 etretinate Drugs 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022171387 | 2022-10-26 | ||
| JP2022171387 | 2022-10-26 | ||
| PCT/JP2023/038716 WO2024090521A1 (ja) | 2022-10-26 | 2023-10-26 | 腎嚢胞性繊毛病の治療及び／又は予防のための医薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2024090521A1 JPWO2024090521A1 (https=) | 2024-05-02 |
| JPWO2024090521A5 true JPWO2024090521A5 (https=) | 2024-12-26 |
| JP7619587B2 JP7619587B2 (ja) | 2025-01-22 |
Family
ID=90830957
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024553135A Active JP7619587B2 (ja) | 2022-10-26 | 2023-10-26 | 腎嚢胞性繊毛病の治療及び／又は予防のための医薬組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US12514834B2 (https=) |
| EP (1) | EP4574171A4 (https=) |
| JP (1) | JP7619587B2 (https=) |
| KR (1) | KR20250089512A (https=) |
| CN (1) | CN120091831A (https=) |
| AU (1) | AU2023367530A1 (https=) |
| WO (1) | WO2024090521A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7837529B1 (ja) * | 2024-11-06 | 2026-03-31 | 国立大学法人京都大学 | 常染色体顕性（優性）多発性嚢胞腎治療用医薬組成物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3633026A4 (en) | 2017-05-25 | 2021-03-10 | Kyoto University | METHOD FOR INDUCING THE DIFFERENTIATION OF A MESODERMAL INTERMEDIATE CELL TO A KIDNEY PRECURSOR CELL AND METHOD FOR INDUCING THE DIFFERENTIATION OF A PLURIPOTENT STEM CELL FROM A KIDNEY PRECURSOR CELL |
| JP2022180668A (ja) | 2019-10-17 | 2022-12-07 | 学校法人杏林学園 | 腎機能障害の治療剤 |
| US20240010989A1 (en) | 2021-01-08 | 2024-01-11 | Kyoto University | Medium for culturing and expanding nephron progenitor cells, method for culturing and expanding nephron progenitor cells, and method for producing renal organoids |
| WO2022210968A1 (ja) | 2021-03-31 | 2022-10-06 | 国立大学法人京都大学 | 嚢胞構造を有する人工集合管オルガノイド |
-
2023
- 2023-10-26 JP JP2024553135A patent/JP7619587B2/ja active Active
- 2023-10-26 EP EP23882723.2A patent/EP4574171A4/en active Pending
- 2023-10-26 AU AU2023367530A patent/AU2023367530A1/en active Pending
- 2023-10-26 KR KR1020257015050A patent/KR20250089512A/ko active Pending
- 2023-10-26 WO PCT/JP2023/038716 patent/WO2024090521A1/ja not_active Ceased
- 2023-10-26 CN CN202380074587.8A patent/CN120091831A/zh active Pending
-
2025
- 2025-01-30 US US19/041,480 patent/US12514834B2/en active Active
- 2025-11-07 US US19/382,699 patent/US20260053763A1/en active Pending
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