JPWO2024043250A1 - - Google Patents

Info

Publication number
JPWO2024043250A1
JPWO2024043250A1 JP2024542834A JP2024542834A JPWO2024043250A1 JP WO2024043250 A1 JPWO2024043250 A1 JP WO2024043250A1 JP 2024542834 A JP2024542834 A JP 2024542834A JP 2024542834 A JP2024542834 A JP 2024542834A JP WO2024043250 A1 JPWO2024043250 A1 JP WO2024043250A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2024542834A
Other languages
Japanese (ja)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2024043250A1 publication Critical patent/JPWO2024043250A1/ja
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K4/00Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2024542834A 2022-08-23 2023-08-23 Abandoned JPWO2024043250A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2022132147 2022-08-23
PCT/JP2023/030223 WO2024043250A1 (ja) 2022-08-23 2023-08-23 環状ペプチドまたはその塩、およびmdmx阻害剤

Publications (1)

Publication Number Publication Date
JPWO2024043250A1 true JPWO2024043250A1 (https=) 2024-02-29

Family

ID=90013421

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024542834A Abandoned JPWO2024043250A1 (https=) 2022-08-23 2023-08-23

Country Status (5)

Country Link
US (1) US20250179120A1 (https=)
EP (1) EP4578868A4 (https=)
JP (1) JPWO2024043250A1 (https=)
TW (1) TW202417465A (https=)
WO (1) WO2024043250A1 (https=)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5605602B2 (ja) 2007-03-26 2014-10-15 国立大学法人 東京大学 環状ペプチド化合物の合成方法
EP2647721B1 (en) * 2010-12-03 2019-02-27 The University of Tokyo Peptide with safer secondary structure, peptide library, and production methods for same
TW202446781A (zh) * 2011-12-28 2024-12-01 日商中外製藥股份有限公司 胜肽化合物之製造方法
EP2819688A4 (en) * 2012-02-15 2015-10-28 Aileron Therapeutics Inc TRIAZOL AND THIOETHER-COUPLED PEPTIDOMIMETIC MACROCYCLES
BR112014020103A2 (pt) 2012-02-15 2018-10-09 Aileron Therapeutics, Inc. macrociclos peptidomiméticos
JP6754997B2 (ja) 2013-08-26 2020-09-16 国立大学法人 東京大学 大環状ペプチド、その製造方法、及び大環状ペプチドライブラリを用いるスクリーニング方法
EP3126375B1 (en) 2014-04-02 2023-12-13 University of Rochester Macrocyclic peptidomimetics for alpha-helix mimicry
IL293239A (en) 2019-11-21 2022-07-01 Unnatural Products Inc Cell-permeable cyclic peptides and their uses
US11939403B2 (en) * 2020-07-02 2024-03-26 The Regents Of The University Of California Peptide-peptoid scaffolds
JP7057003B1 (ja) * 2021-02-26 2022-04-19 国立大学法人東京工業大学 予測装置、学習済みモデルの生成装置、予測方法、学習済みモデルの生成方法、予測プログラム、及び学習済みモデルの生成プログラム
TW202313092A (zh) * 2021-05-26 2023-04-01 美商非自然產物公司 細胞可穿透環狀肽及其用途
TW202417032A (zh) * 2022-08-23 2024-05-01 日商富士軟片股份有限公司 環肽或其鹽及mdmx抑制劑
JPWO2024043251A1 (https=) * 2022-08-23 2024-02-29

Also Published As

Publication number Publication date
US20250179120A1 (en) 2025-06-05
EP4578868A4 (en) 2025-12-17
TW202417465A (zh) 2024-05-01
WO2024043250A1 (ja) 2024-02-29
EP4578868A1 (en) 2025-07-02

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Legal Events

Date Code Title Description
A762 Written abandonment of application

Free format text: JAPANESE INTERMEDIATE CODE: A762

Effective date: 20251222