JPWO2023214512A1 - - Google Patents
Info
- Publication number
- JPWO2023214512A1 JPWO2023214512A1 JP2024519192A JP2024519192A JPWO2023214512A1 JP WO2023214512 A1 JPWO2023214512 A1 JP WO2023214512A1 JP 2024519192 A JP2024519192 A JP 2024519192A JP 2024519192 A JP2024519192 A JP 2024519192A JP WO2023214512 A1 JPWO2023214512 A1 JP WO2023214512A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/33—Alteration of splicing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022076674 | 2022-05-06 | ||
| PCT/JP2023/015828 WO2023214512A1 (ja) | 2022-05-06 | 2023-04-20 | 人工ｒｎａ分子 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023214512A1 true JPWO2023214512A1 (https=) | 2023-11-09 |
| JPWO2023214512A5 JPWO2023214512A5 (https=) | 2025-01-20 |
Family
ID=88646433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024519192A Pending JPWO2023214512A1 (https=) | 2022-05-06 | 2023-04-20 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20250297253A1 (https=) |
| EP (1) | EP4520825A1 (https=) |
| JP (1) | JPWO2023214512A1 (https=) |
| WO (1) | WO2023214512A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025217551A1 (en) * | 2024-04-12 | 2025-10-16 | University Of Miami | Microrna-mediated obstruction of stem-loop alternative splicing |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013521791A (ja) * | 2010-03-17 | 2013-06-13 | アソシアシオン インスティテュト ドゥ ミョロジー | 神経筋疾患の治療のための修飾型Ｕ７ｓｎＲＮＡ |
| JP2019519218A (ja) * | 2016-05-18 | 2019-07-11 | ボイジャー セラピューティクス インコーポレイテッドＶｏｙａｇｅｒ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | 調節性ポリヌクレオチド |
| WO2021117729A1 (ja) * | 2019-12-09 | 2021-06-17 | アステラス製薬株式会社 | 標的ｒｎａを編集するための機能性領域を付加したアンチセンス型ガイドｒｎａ |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI541024B (zh) | 2010-09-01 | 2016-07-11 | 日本新藥股份有限公司 | 反義核酸 |
| MX2018007987A (es) | 2015-12-28 | 2019-01-10 | Novartis Ag | Composiciones y metodos para el tratamiento de hemoglobinopatias. |
-
2023
- 2023-04-20 WO PCT/JP2023/015828 patent/WO2023214512A1/ja not_active Ceased
- 2023-04-20 EP EP23799444.7A patent/EP4520825A1/en active Pending
- 2023-04-20 US US18/863,254 patent/US20250297253A1/en active Pending
- 2023-04-20 JP JP2024519192A patent/JPWO2023214512A1/ja active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013521791A (ja) * | 2010-03-17 | 2013-06-13 | アソシアシオン インスティテュト ドゥ ミョロジー | 神経筋疾患の治療のための修飾型Ｕ７ｓｎＲＮＡ |
| JP2019519218A (ja) * | 2016-05-18 | 2019-07-11 | ボイジャー セラピューティクス インコーポレイテッドＶｏｙａｇｅｒ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | 調節性ポリヌクレオチド |
| WO2021117729A1 (ja) * | 2019-12-09 | 2021-06-17 | アステラス製薬株式会社 | 標的ｒｎａを編集するための機能性領域を付加したアンチセンス型ガイドｒｎａ |
Non-Patent Citations (2)
| Title |
|---|
| FUMIO HARADA ET AL.: "Nucleotide sequences of 4.5S RNAs associated with poly (A) -containing RNAs of mouse and hamster cel", NUCLEIC ACIDS RESEARCH, vol. 8, no. 6, JPN6025038760, 1980, pages 1273 - 1286, ISSN: 0005813626 * |
| ISHIDA, KENTARO ET AL.: "Regulation of gene expression via retrotransposon insertions and the noncoding RNA 4.5S RNAH", GENES TO CELLS, vol. 20, no. 11, JPN6023028287, 3 September 2015 (2015-09-03), pages 887 - 901, ISSN: 0005698322 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4520825A1 (en) | 2025-03-12 |
| WO2023214512A1 (ja) | 2023-11-09 |
| US20250297253A1 (en) | 2025-09-25 |
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