JPWO2023171698A5 - - Google Patents
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- Publication number
- JPWO2023171698A5 JPWO2023171698A5 JP2024506360A JP2024506360A JPWO2023171698A5 JP WO2023171698 A5 JPWO2023171698 A5 JP WO2023171698A5 JP 2024506360 A JP2024506360 A JP 2024506360A JP 2024506360 A JP2024506360 A JP 2024506360A JP WO2023171698 A5 JPWO2023171698 A5 JP WO2023171698A5
- Authority
- JP
- Japan
- Prior art keywords
- gene
- producer cell
- exogenous promoter
- control
- under
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 24
- 101150044789 Cap gene Proteins 0.000 claims 14
- 101150066583 rep gene Proteins 0.000 claims 14
- 101150066038 E4 gene Proteins 0.000 claims 13
- 210000000349 chromosome Anatomy 0.000 claims 11
- 108090000623 proteins and genes Proteins 0.000 claims 10
- 238000003780 insertion Methods 0.000 claims 8
- 230000037431 insertion Effects 0.000 claims 8
- 241000702421 Dependoparvovirus Species 0.000 claims 6
- 108091034131 VA RNA Proteins 0.000 claims 5
- 238000012258 culturing Methods 0.000 claims 5
- 101150082674 E2 gene Proteins 0.000 claims 4
- 210000004962 mammalian cell Anatomy 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 239000004098 Tetracycline Substances 0.000 claims 2
- 108091023040 Transcription factor Proteins 0.000 claims 2
- 102000040945 Transcription factor Human genes 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000001105 regulatory effect Effects 0.000 claims 2
- 229960002180 tetracycline Drugs 0.000 claims 2
- 229930101283 tetracycline Natural products 0.000 claims 2
- 235000019364 tetracycline Nutrition 0.000 claims 2
- 150000003522 tetracyclines Chemical class 0.000 claims 2
- 230000002103 transcriptional effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022035100 | 2022-03-08 | ||
| JP2023024167 | 2023-02-20 | ||
| PCT/JP2023/008736 WO2023171698A1 (ja) | 2022-03-08 | 2023-03-08 | プロデューサー細胞、プロデューサー細胞の製造方法、およびアデノ随伴ウイルスの製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023171698A1 JPWO2023171698A1 (https=) | 2023-09-14 |
| JPWO2023171698A5 true JPWO2023171698A5 (https=) | 2024-11-14 |
Family
ID=87935079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024506360A Pending JPWO2023171698A1 (https=) | 2022-03-08 | 2023-03-08 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240425826A1 (https=) |
| EP (1) | EP4491717A4 (https=) |
| JP (1) | JPWO2023171698A1 (https=) |
| CN (1) | CN119278268A (https=) |
| WO (1) | WO2023171698A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025168663A1 (en) | 2024-02-09 | 2025-08-14 | F. Hoffmann-La Roche Ag | Method for producing recombinant adeno-associated viral particles |
| WO2026022064A1 (en) | 2024-07-22 | 2026-01-29 | F. Hoffmann-La Roche Ag | Novel aav rep orfs and rep polypeptides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3008736B2 (ja) | 1993-07-02 | 2000-02-14 | 松下電器産業株式会社 | 超音波式車両感知器 |
| DE10056210A1 (de) * | 2000-11-13 | 2002-05-29 | Arimedes Biotechnology Gmbh | Virales Expressionssystem |
| EP3456822A1 (en) * | 2017-09-19 | 2019-03-20 | CEVEC Pharmaceuticals GmbH | Inducible aav rep genes |
| GB201816919D0 (en) * | 2018-10-17 | 2018-11-28 | Glaxosmithkline Ip Dev Ltd | Adeno-associated viral vector producer cell lines |
| CN113396222A (zh) * | 2018-12-21 | 2021-09-14 | 隆萨沃克斯维尔股份有限公司 | 腺相关病毒(aav)生产细胞系和相关方法 |
-
2023
- 2023-03-08 JP JP2024506360A patent/JPWO2023171698A1/ja active Pending
- 2023-03-08 CN CN202380026191.6A patent/CN119278268A/zh active Pending
- 2023-03-08 WO PCT/JP2023/008736 patent/WO2023171698A1/ja not_active Ceased
- 2023-03-08 EP EP23766874.4A patent/EP4491717A4/en active Pending
-
2024
- 2024-09-06 US US18/827,497 patent/US20240425826A1/en active Pending
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