JPWO2023170474A5 - - Google Patents

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Publication number
JPWO2023170474A5
JPWO2023170474A5 JP2024553409A JP2024553409A JPWO2023170474A5 JP WO2023170474 A5 JPWO2023170474 A5 JP WO2023170474A5 JP 2024553409 A JP2024553409 A JP 2024553409A JP 2024553409 A JP2024553409 A JP 2024553409A JP WO2023170474 A5 JPWO2023170474 A5 JP WO2023170474A5
Authority
JP
Japan
Prior art keywords
amino acid
acid sequence
seq
light chain
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024553409A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025508066A (ja
JP2025508066A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2023/000124 external-priority patent/WO2023170474A1/en
Publication of JP2025508066A publication Critical patent/JP2025508066A/ja
Publication of JPWO2023170474A5 publication Critical patent/JPWO2023170474A5/ja
Publication of JP2025508066A5 publication Critical patent/JP2025508066A5/ja
Pending legal-status Critical Current

Links

JP2024553409A 2022-03-07 2023-03-07 目的としたt細胞活性化のためのcd28二重特異性抗体 Pending JP2025508066A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263317491P 2022-03-07 2022-03-07
US63/317,491 2022-03-07
US202263323893P 2022-03-25 2022-03-25
US63/323,893 2022-03-25
PCT/IB2023/000124 WO2023170474A1 (en) 2022-03-07 2023-03-07 Cd28 bispecific antibodies for targeted t cell activation

Publications (3)

Publication Number Publication Date
JP2025508066A JP2025508066A (ja) 2025-03-21
JPWO2023170474A5 true JPWO2023170474A5 (https=) 2026-03-17
JP2025508066A5 JP2025508066A5 (https=) 2026-03-17

Family

ID=86272440

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024553409A Pending JP2025508066A (ja) 2022-03-07 2023-03-07 目的としたt細胞活性化のためのcd28二重特異性抗体

Country Status (8)

Country Link
US (1) US20240002544A1 (https=)
EP (1) EP4490192A1 (https=)
JP (1) JP2025508066A (https=)
CN (1) CN119233993A (https=)
AU (1) AU2023232992A1 (https=)
CA (1) CA3249273A1 (https=)
IL (1) IL314916A (https=)
WO (1) WO2023170474A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3212599A1 (en) * 2021-03-22 2022-09-29 Novimmune S.A. Bispecific antibodies targeting cd47 and pd-l1 and methods of use thereof
CN119095873A (zh) 2022-03-14 2024-12-06 拉姆卡普生物伽马股份公司 用于靶向杀伤GPC3阳性恶性细胞的双特异性GPC3xCD28和GPC3xCD3抗体及其组合
WO2024084052A1 (en) 2022-10-21 2024-04-25 Novimmune Sa Pd-l1xcd28 bispecific antibodies for immune checkpoint-dependent t cell activation
WO2025051895A1 (en) * 2023-09-06 2025-03-13 Novimmune Sa Combination therapy with a cea x cd28 bispecific antibody and blocking anti-pd-1 antibodies for enhanced in vivo anti-tumor activity
TW202544034A (zh) * 2024-05-06 2025-11-16 美商榮都醫療公司 結合至cd28及nectin-4之雙特異性抗體
WO2026078067A1 (en) 2024-10-08 2026-04-16 Novimmune Sa Fcrh5 monospecific antibodies and derived fcrh5xcd28 bispecific antibodies and use thereof

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