JPWO2023161291A5 - - Google Patents

Info

Publication number
JPWO2023161291A5
JPWO2023161291A5 JP2024549592A JP2024549592A JPWO2023161291A5 JP WO2023161291 A5 JPWO2023161291 A5 JP WO2023161291A5 JP 2024549592 A JP2024549592 A JP 2024549592A JP 2024549592 A JP2024549592 A JP 2024549592A JP WO2023161291 A5 JPWO2023161291 A5 JP WO2023161291A5
Authority
JP
Japan
Prior art keywords
antibody
peptide linker
payload
peptide
linker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024549592A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025506768A (ja
JP2025506768A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2023/054455 external-priority patent/WO2023161291A1/en
Publication of JP2025506768A publication Critical patent/JP2025506768A/ja
Publication of JP2025506768A5 publication Critical patent/JP2025506768A5/ja
Publication of JPWO2023161291A5 publication Critical patent/JPWO2023161291A5/ja
Pending legal-status Critical Current

Links

JP2024549592A 2022-02-22 2023-02-22 2つ以上のペイロードを含むペプチドリンカー Pending JP2025506768A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22158100.2 2022-02-22
EP22158100 2022-02-22
PCT/EP2023/054455 WO2023161291A1 (en) 2022-02-22 2023-02-22 Peptide linkers comprising two or more payloads

Publications (3)

Publication Number Publication Date
JP2025506768A JP2025506768A (ja) 2025-03-13
JP2025506768A5 JP2025506768A5 (https=) 2026-03-02
JPWO2023161291A5 true JPWO2023161291A5 (https=) 2026-03-02

Family

ID=80447107

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024549592A Pending JP2025506768A (ja) 2022-02-22 2023-02-22 2つ以上のペイロードを含むペプチドリンカー

Country Status (8)

Country Link
US (1) US20250082774A1 (https=)
EP (1) EP4482529A1 (https=)
JP (1) JP2025506768A (https=)
KR (1) KR20240150807A (https=)
CN (1) CN118742328A (https=)
AU (1) AU2023223556A1 (https=)
CA (1) CA3243937A1 (https=)
WO (1) WO2023161291A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240038138A (ko) 2020-07-13 2024-03-22 리제너론 파마슈티칼스 인코포레이티드 단백질에서 글루타민 잔기에 접합된 캄토테신 유사체 및 그의 용도
IL321285A (en) * 2022-12-21 2025-08-01 Regeneron Pharma Topoisomerase I inhibitor prodrugs for ADC conjugates and a regimen for their use
WO2025082990A1 (en) 2023-10-15 2025-04-24 Araris Biotech Ag Antibody-drug conjugates using two different types of topoisomerase i inhibitors
WO2026013234A1 (en) 2024-07-10 2026-01-15 Araris Biotech Ag Triple-payload antibody-drug conjugates (adcs)

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US4137230A (en) 1977-11-14 1979-01-30 Takeda Chemical Industries, Ltd. Method for the production of maytansinoids
US4265814A (en) 1978-03-24 1981-05-05 Takeda Chemical Industries Matansinol 3-n-hexadecanoate
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