JPWO2023137403A5 - - Google Patents

Info

Publication number
JPWO2023137403A5
JPWO2023137403A5 JP2024541745A JP2024541745A JPWO2023137403A5 JP WO2023137403 A5 JPWO2023137403 A5 JP WO2023137403A5 JP 2024541745 A JP2024541745 A JP 2024541745A JP 2024541745 A JP2024541745 A JP 2024541745A JP WO2023137403 A5 JPWO2023137403 A5 JP WO2023137403A5
Authority
JP
Japan
Prior art keywords
compound
alkyl
group
independently
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024541745A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025502191A5 (https=
JP2025502191A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/060594 external-priority patent/WO2023137403A2/en
Publication of JP2025502191A publication Critical patent/JP2025502191A/ja
Publication of JP2025502191A5 publication Critical patent/JP2025502191A5/ja
Publication of JPWO2023137403A5 publication Critical patent/JPWO2023137403A5/ja
Pending legal-status Critical Current

Links

JP2024541745A 2022-01-12 2023-01-12 治療剤に結合したラルチトレキセドまたは5-mthfを含む化合物、組成物、および使用する方法 Pending JP2025502191A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263298793P 2022-01-12 2022-01-12
US63/298,793 2022-01-12
US202263299261P 2022-01-13 2022-01-13
US63/299,261 2022-01-13
PCT/US2023/060594 WO2023137403A2 (en) 2022-01-12 2023-01-12 Compound comprising raltitrexed or 5-mthf linked to a therapeutic agent, composition, and method of use

Publications (3)

Publication Number Publication Date
JP2025502191A JP2025502191A (ja) 2025-01-24
JP2025502191A5 JP2025502191A5 (https=) 2026-01-27
JPWO2023137403A5 true JPWO2023137403A5 (https=) 2026-01-27

Family

ID=87279733

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024541745A Pending JP2025502191A (ja) 2022-01-12 2023-01-12 治療剤に結合したラルチトレキセドまたは5-mthfを含む化合物、組成物、および使用する方法

Country Status (6)

Country Link
US (1) US20250222117A1 (https=)
EP (1) EP4463149A2 (https=)
JP (1) JP2025502191A (https=)
KR (1) KR20240150763A (https=)
CA (2) CA3248149A1 (https=)
WO (1) WO2023137403A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023230616A2 (en) * 2022-05-26 2023-11-30 Purdue Research Foundation Combination of small molecule drug conjugate and car-expressing cytotoxic lymphocytes and methods of use
WO2024186626A1 (en) * 2023-03-03 2024-09-12 Bolt Biotherapeutics, Inc. Aza-bicyclic sting agonist immunoconjugates, and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL305483A (en) * 2018-03-20 2023-10-01 Dana Farber Cancer Inst Inc Preparations and methods for the treatment of cancer

Similar Documents

Publication Publication Date Title
EP3464277B1 (en) Pegylated carfilzomib compounds
CA3004444C (en) Polyethylene glycol-conjugated glucocorticoid prodrugs and compositions and methods thereof
RU2240325C2 (ru) Стероидное соединение, фармацевтические композиции
US10626139B2 (en) Cationic steroidal antimicrobial compounds
DE69429364T2 (de) Verwendung von steroidderivaten als arzneimittel
ES2657907T3 (es) Aplicaciones terapéuticas de ectoína
US20090221543A1 (en) New corticosteroids
JP4388600B2 (ja) コルチコイド化合物の硝酸エステル類およびその薬学的使用
US20170210776A1 (en) Cationic steroidal antimicrobials
EP2456781A2 (de) 17-hydroxy-17-pentafluorethyl-estra-4,9 (10)-dien-11-acyloxyalkylenphenyl-derivate, verfahren zu ihrer herstellung und ihre verwendung zur behandlung von krankheiten
RU99108661A (ru) Нитроэфиры кортикоидных соединений и их фармацевтические применения
AU2007222282B2 (en) Use of 3,5-seco-4-norcholestane derivatives for obtaining a cytoprotective medicament
CN117964577B (zh) 阳离子脂质化合物、其制备方法、包含其的组合物及应用
EP1940863B1 (en) Nitrooxy derivatives of glucocorticoids
HRP20160624T1 (hr) Derivati sterola, postupci njihove pripreme, farmaceutski pripravci koji ih sadrže i njihova uporaba za liječenje multiplih glioblastoma
JPWO2023137403A5 (https=)
JPS5955900A (ja) コルチコステロイド誘導体類
JP2667418B2 (ja) グルココルチコイド的性質及び抗炎症性を有する,含硫アミノ酸又は非含硫アミノ酸と△―4―プレグネン―3,20―ジオン誘導体又は△―1,4―プレグナジエン―3,20―ジオン誘導体との結合合成化合物,製造方法,それ等を含む医薬組成物,薬理活性及び使用
CN107108761B (zh) 硫酸软骨素衍生物和膀胱疾病处置剂
US4810701A (en) 11-desoxy-17α-hydroxycorticosterone derivatives
JP2025542006A (ja) ペプチド薬物コンジュゲート
CN118930839A (zh) 聚合物脂质化合物及其组合物、制备和用途
BR112018074078B1 (pt) Compostos de carfilzomib peguilados e composição farmacêutica