JPWO2023112931A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2023112931A5 JPWO2023112931A5 JP2023567797A JP2023567797A JPWO2023112931A5 JP WO2023112931 A5 JPWO2023112931 A5 JP WO2023112931A5 JP 2023567797 A JP2023567797 A JP 2023567797A JP 2023567797 A JP2023567797 A JP 2023567797A JP WO2023112931 A5 JPWO2023112931 A5 JP WO2023112931A5
- Authority
- JP
- Japan
- Prior art keywords
- bonds
- nucleosides
- wing region
- antisense oligonucleotide
- pharma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024214710A JP2025038021A (ja) | 2021-12-13 | 2024-12-09 | ＡＴＮ１ ｍＲＮＡ又はｐｒｅ－ｍＲＮＡを標的とするアンチセンスオリゴヌクレオチド |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021201756 | 2021-12-13 | ||
| JP2021201756 | 2021-12-13 | ||
| JP2022184853 | 2022-11-18 | ||
| JP2022184853 | 2022-11-18 | ||
| PCT/JP2022/045921 WO2023112931A1 (ja) | 2021-12-13 | 2022-12-13 | ＡＴＮ１ ｍＲＮＡ又はｐｒｅ－ｍＲＮＡを標的とするアンチセンスオリゴヌクレオチド |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024214710A Division JP2025038021A (ja) | 2021-12-13 | 2024-12-09 | ＡＴＮ１ ｍＲＮＡ又はｐｒｅ－ｍＲＮＡを標的とするアンチセンスオリゴヌクレオチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2023112931A1 JPWO2023112931A1 (https=) | 2023-06-22 |
| JPWO2023112931A5 true JPWO2023112931A5 (https=) | 2024-07-01 |
| JP7607884B2 JP7607884B2 (ja) | 2025-01-06 |
Family
ID=86774345
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023567797A Active JP7607884B2 (ja) | 2021-12-13 | 2022-12-13 | ＡＴＮ１ ｍＲＮＡ又はｐｒｅ－ｍＲＮＡを標的とするアンチセンスオリゴヌクレオチド |
| JP2024214710A Pending JP2025038021A (ja) | 2021-12-13 | 2024-12-09 | ＡＴＮ１ ｍＲＮＡ又はｐｒｅ－ｍＲＮＡを標的とするアンチセンスオリゴヌクレオチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024214710A Pending JP2025038021A (ja) | 2021-12-13 | 2024-12-09 | ＡＴＮ１ ｍＲＮＡ又はｐｒｅ－ｍＲＮＡを標的とするアンチセンスオリゴヌクレオチド |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20250051769A1 (https=) |
| EP (1) | EP4450625A1 (https=) |
| JP (2) | JP7607884B2 (https=) |
| TW (1) | TW202340464A (https=) |
| WO (1) | WO2023112931A1 (https=) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2924179B2 (ja) | 1993-02-19 | 1999-07-26 | 日本新薬株式会社 | グリセロール誘導体，デバイス及び医薬組成物 |
| EP2601294B1 (en) * | 2010-08-05 | 2018-11-28 | Academisch Ziekenhuis Leiden h.o.d.n. LUMC | Antisense oligonucleotide directed removal of proteolytic cleavage sites from proteins |
| BR112020018902A2 (pt) | 2018-03-20 | 2021-01-26 | Tokyo Institute Of Technology | oligonucleotídeo antissenso com toxicidade reduzida |
| KR20220133925A (ko) | 2020-01-31 | 2022-10-05 | 가부시키가이샤산와카가쿠켄큐쇼 | Atn1의 안티센스 올리고뉴클레오티드 |
| JPWO2022211129A1 (https=) | 2021-04-01 | 2022-10-06 | ||
| WO2023164656A2 (en) | 2022-02-25 | 2023-08-31 | Ionis Pharmaceuticals, Inc. | Compounds and methods for modulating atn1 expression |
| WO2023201281A2 (en) | 2022-04-14 | 2023-10-19 | University Of Massachusetts | Oligonucleotides for atn1 modulation |
-
2022
- 2022-12-13 WO PCT/JP2022/045921 patent/WO2023112931A1/ja not_active Ceased
- 2022-12-13 EP EP22907455.4A patent/EP4450625A1/en active Pending
- 2022-12-13 JP JP2023567797A patent/JP7607884B2/ja active Active
- 2022-12-13 US US18/719,037 patent/US20250051769A1/en active Pending
- 2022-12-13 TW TW111147856A patent/TW202340464A/zh unknown
-
2024
- 2024-06-12 US US18/741,110 patent/US12291710B2/en active Active
- 2024-12-09 JP JP2024214710A patent/JP2025038021A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN112274647B (zh) | 寡聚物和寡聚物缀合物 | |
| JP7748500B2 (ja) | トリループを含む二本鎖核酸インヒビター分子 | |
| KR100991975B1 (ko) | 핵산을 기본으로 하는 화합물 및 이의 사용방법 | |
| JP2019141097A5 (https=) | ||
| KR20180134364A (ko) | 트리틸-모노-GalNAc 화합물 및 이의 용도 | |
| CN110832077B (zh) | 用于抑制α-ENaC表达的RNAi剂及使用方法 | |
| JP2019534009A5 (https=) | ||
| US20240368593A1 (en) | Gapmer oligonucleotides comprising a phosphorodithioate internucleoside linkage | |
| JP2005522997A (ja) | 交代セグメントを含むオリゴヌクレオチド及びその用途 | |
| JP2009532044A5 (https=) | ||
| CN106459969A (zh) | 用于调节生长激素受体表达的组合物和方法 | |
| CA3072314A1 (en) | Nucleic acid molecule for reduction of papd5 and papd7 mrna for treating hepatitis b infection | |
| CN121079412A (zh) | 经修饰的指导rna | |
| CN111448316B (zh) | 新的硫代亚磷酰胺 | |
| CN104321334A (zh) | 三环核苷及由其制备的低聚化合物 | |
| JP2000514093A (ja) | Ｃｍｖ感染症の治療のための組成物および方法 | |
| TWI791868B (zh) | 調節rtel1表現之寡核苷酸 | |
| CN113795581A (zh) | 具有缩短的有义链的双链核酸抑制剂分子 | |
| JPWO2023112931A5 (https=) | ||
| JP7476102B2 (ja) | ホスホロジチオアートヌクレオシド間結合を含むオリゴヌクレオチド | |
| US20240336920A1 (en) | Threose nucleic acid antisense oligonucleotides and methods thereof | |
| TW202345861A (zh) | 經修飾之間隔體寡聚物及其使用方法 | |
| EP4332221A1 (en) | Threose nucleic acid antisense oligonucleotides and methods thereof | |
| WO2022266486A2 (en) | Products and compositions | |
| CN115279904A (zh) | 抑制asah1基因表达的组合物和方法 |