JPWO2023111311A5 - - Google Patents

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Publication number
JPWO2023111311A5
JPWO2023111311A5 JP2024536163A JP2024536163A JPWO2023111311A5 JP WO2023111311 A5 JPWO2023111311 A5 JP WO2023111311A5 JP 2024536163 A JP2024536163 A JP 2024536163A JP 2024536163 A JP2024536163 A JP 2024536163A JP WO2023111311 A5 JPWO2023111311 A5 JP WO2023111311A5
Authority
JP
Japan
Prior art keywords
seq
isoform
vlcdr2
vhcdr2
vlcdr3
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024536163A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024546996A (ja
JP2024546996A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/086452 external-priority patent/WO2023111311A1/en
Publication of JP2024546996A publication Critical patent/JP2024546996A/ja
Publication of JPWO2023111311A5 publication Critical patent/JPWO2023111311A5/ja
Publication of JP2024546996A5 publication Critical patent/JP2024546996A5/ja
Pending legal-status Critical Current

Links

JP2024536163A 2021-12-16 2022-12-16 細胞療法に使用するためのcd117の識別可能な細胞表面タンパク質変異体 Pending JP2024546996A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP21215028 2021-12-16
EP21215028.8 2021-12-16
EP22164796 2022-03-28
EP22164796.9 2022-03-28
EP22207926.1 2022-11-16
EP22207926 2022-11-16
PCT/EP2022/086452 WO2023111311A1 (en) 2021-12-16 2022-12-16 Discernible cell surface protein variants of cd117 for use in cell therapy

Publications (3)

Publication Number Publication Date
JP2024546996A JP2024546996A (ja) 2024-12-26
JPWO2023111311A5 true JPWO2023111311A5 (https=) 2025-12-23
JP2024546996A5 JP2024546996A5 (https=) 2025-12-23

Family

ID=84981434

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024536163A Pending JP2024546996A (ja) 2021-12-16 2022-12-16 細胞療法に使用するためのcd117の識別可能な細胞表面タンパク質変異体

Country Status (10)

Country Link
US (1) US20250057951A1 (https=)
EP (1) EP4448573A1 (https=)
JP (1) JP2024546996A (https=)
KR (1) KR20240115920A (https=)
AU (1) AU2022409748A1 (https=)
CA (1) CA3240527A1 (https=)
IL (1) IL313568A (https=)
MX (1) MX2024007317A (https=)
WO (1) WO2023111311A1 (https=)
ZA (1) ZA202405110B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4540287A1 (en) * 2022-06-20 2025-04-23 CRISPR Therapeutics AG Chimeric antigen receptor specific to cd117
KR20250034296A (ko) * 2022-07-07 2025-03-11 씨메이오 테라퓨틱스 아게 Cd117을 표적화하는 항체
WO2025231071A1 (en) * 2024-05-01 2025-11-06 Beam Therapeutics Inc. Compositions and methods for cell conditioning

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0578774T3 (da) 1991-04-05 1999-04-26 Univ Washington Monoklonale antistoffer mod stamcellefaktor-receptorer
TWI395754B (zh) 2006-04-24 2013-05-11 Amgen Inc 人類化之c-kit抗體
WO2015050959A1 (en) 2013-10-01 2015-04-09 Yale University Anti-kit antibodies and methods of use thereof
US10786578B2 (en) 2014-08-05 2020-09-29 Novartis Ag CKIT antibody drug conjugates
US11499168B2 (en) 2016-04-25 2022-11-15 Universitat Basel Allele editing and applications thereof
AU2017355218B2 (en) 2016-11-02 2024-02-22 Universität Basel Immunologically discernible cell surface variants for use in cell therapy
SG11201907870VA (en) 2017-02-28 2019-09-27 Vor Biopharma Inc Compositions and methods for inhibition of lineage specific proteins
TWI687227B (zh) * 2017-10-03 2020-03-11 生倍科技股份有限公司 用於t細胞免疫療法之組合及其用途
CA3079215A1 (en) * 2017-10-24 2019-05-02 Magenta Therapeutics, Inc. Compositions and methods for the depletion of cd117+ cells
CA3079897A1 (en) 2017-10-24 2019-05-02 Magenta Therapeutics, Inc. Compositions and methods for the depletion of cd117+ cells
US12378318B2 (en) * 2018-08-08 2025-08-05 Dragonfly Therapeutics, Inc. Proteins binding NKG2D, CD16 and a tumor-associated antigen
CN119684457A (zh) 2018-11-26 2025-03-25 四十七有限责任公司 针对c-kit的人源化抗体
JP2022529727A (ja) * 2019-04-24 2022-06-23 マジェンタ セラピューティクス インコーポレイテッド Anti-cd117 とその使用
US20230017979A1 (en) 2019-08-29 2023-01-19 Beam Therapeutics Inc. Compositions and methods for non-toxic conditioning

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