|
MX9205293A
(es)
|
1991-09-20 |
1993-05-01 |
Syntex Sinergen Neuroscience J |
Factores neurotrofico derivado del glial
|
|
US6184200B1
(en)
|
1995-09-28 |
2001-02-06 |
Amgen Inc. |
Truncated glial cell line-derived neurotrophic factor
|
|
US5865744A
(en)
|
1996-09-16 |
1999-02-02 |
Lemelson; Jerome H. |
Method and system for delivering therapeutic agents
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
ES2340230T3
(es)
|
1998-11-10 |
2010-05-31 |
University Of North Carolina At Chapel Hill |
Vectores viricos y sus procedimientos de preparacion y administracion.
|
|
AU1071701A
(en)
|
1999-09-29 |
2001-04-30 |
Trustees Of The University Of Pennsylvania, The |
Methods for rapid peg-modification of viral vectors, compositions for enhanced gene transduction, compositions with enhanced physical stability, and uses therefor
|
|
US20030050273A1
(en)
*
|
2001-08-29 |
2003-03-13 |
Keiya Ozawa |
Compositions and methods for treating neurodegenerative diseases
|
|
AU2002359284A1
(en)
|
2001-12-17 |
2003-06-30 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus (aav) serotype 9 sequences, vectors containing same, and uses therefor
|
|
SI3235827T1
(sl)
|
2003-06-19 |
2021-05-31 |
Genzyme Corporation |
AAV virioni z zmanjšano imunoreaktivnostjo in uporaba za ta namen
|
|
US9233131B2
(en)
|
2003-06-30 |
2016-01-12 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
US9441244B2
(en)
|
2003-06-30 |
2016-09-13 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
CN1856576B
(zh)
|
2003-09-30 |
2011-05-04 |
宾夕法尼亚州立大学托管会 |
腺伴随病毒(aav)进化支、序列、含有这些序列的载体及它们的应用
|
|
WO2005072364A2
(en)
|
2004-01-27 |
2005-08-11 |
University Of Florida |
A modified baculovirus expression system for production of pseudotyped raav vector
|
|
CN101213305A
(zh)
*
|
2004-12-09 |
2008-07-02 |
建新公司 |
转基因在哺乳动物中枢神经系统中的可调控型表达
|
|
WO2006110689A2
(en)
|
2005-04-07 |
2006-10-19 |
The Trustees Of The University Of Pennsylvania |
Method of increasing the function of an aav vector
|
|
US20100203083A1
(en)
|
2007-05-31 |
2010-08-12 |
Medigene Ag |
Mutated structural protein of a parvovirus
|
|
FI20070808A0
(fi)
|
2007-10-25 |
2007-10-25 |
Mart Saarma |
GDNF:n silmukointivariantit ja niiden käytöt
|
|
US8340743B2
(en)
|
2007-11-21 |
2012-12-25 |
MRI Interventions, Inc. |
Methods, systems and computer program products for positioning a guidance apparatus relative to a patient
|
|
EP2910637A1
(en)
|
2008-05-20 |
2015-08-26 |
University of Florida Research Foundation, Inc. |
Vectors for delivery of light-sensitive proteins and methods of use
|
|
JP5559185B2
(ja)
*
|
2008-11-11 |
2014-07-23 |
オックスフォード バイオメディカ(ユーケー)リミテッド |
方法
|
|
EP2396343B1
(en)
|
2009-02-11 |
2017-05-17 |
The University of North Carolina At Chapel Hill |
Modified virus vectors and methods of making and using the same
|
|
WO2010138263A2
(en)
|
2009-05-28 |
2010-12-02 |
University Of Massachusetts |
Novel aav 's and uses thereof
|
|
WO2011117258A2
(en)
|
2010-03-22 |
2011-09-29 |
Association Institut De Myologie |
Methods of increasing efficiency of vector penetration of target tissue
|
|
EP2826860B1
(en)
|
2010-04-23 |
2018-08-22 |
University of Massachusetts |
CNS targeting AAV vectors and methods of use thereof
|
|
EP2634253B1
(en)
|
2010-10-27 |
2016-05-11 |
Jichi Medical University |
Adeno-associated virus virions for transferring genes into neural cells
|
|
ES2857773T5
(es)
|
2011-08-24 |
2024-06-04 |
Univ Leland Stanford Junior |
Nuevas proteínas de la cápside de AAV para la transferencia de ácidos nucleicos
|
|
WO2013096955A1
(en)
|
2011-12-23 |
2013-06-27 |
Case Western Reserve University |
Targeted gene modification using hybrid recombinant adeno-associated virus
|
|
AU2013221212B2
(en)
|
2012-02-17 |
2018-08-09 |
The Children's Hospital Of Philadelphia |
AAV vector compositions and methods for gene transfer to cells, organs and tissues
|
|
US9636370B2
(en)
|
2012-09-28 |
2017-05-02 |
The University Of North Carolina At Chapel Hill |
AAV vectors targeted to oligodendrocytes
|
|
US9567376B2
(en)
|
2013-02-08 |
2017-02-14 |
The Trustees Of The University Of Pennsylvania |
Enhanced AAV-mediated gene transfer for retinal therapies
|
|
JP6396988B2
(ja)
|
2013-03-15 |
2018-09-26 |
ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル |
二重グリカン結合性aavベクターのための方法および組成物
|
|
US9585971B2
(en)
|
2013-09-13 |
2017-03-07 |
California Institute Of Technology |
Recombinant AAV capsid protein
|
|
WO2015048534A1
(en)
|
2013-09-26 |
2015-04-02 |
University Of Florida Research Foundation, Inc. |
Synthetic combinatorial aav capsid library for targeted gene therapy
|
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
|
IL248102B
(en)
|
2014-05-02 |
2022-07-01 |
Genzyme Corp |
aav vectors for gene therapy of the central nervous system and retina
|
|
WO2015191508A1
(en)
|
2014-06-09 |
2015-12-17 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
WO2016005004A1
(en)
|
2014-07-11 |
2016-01-14 |
Biontech Rna Pharmaceuticals Gmbh |
Stabilization of poly(a) sequence encoding dna sequences
|
|
BR112017005892A2
(pt)
|
2014-09-24 |
2017-12-12 |
Hope City |
variantes de vetor de vírus adeno-associado para edição de genoma de alta eficácia e métodos da mesma
|
|
AU2015335923B2
(en)
|
2014-10-21 |
2021-04-29 |
University Of Massachusetts |
Recombinant AAV variants and uses thereof
|
|
SG11201703148TA
(en)
*
|
2014-11-05 |
2017-05-30 |
Voyager Therapeutics Inc |
Aadc polynucleotides for the treatment of parkinson's disease
|
|
DE202015010000U1
(de)
|
2014-12-12 |
2023-07-03 |
CureVac SE |
Artifizielle Nukleinsäuremoleküle für eine verbesserte Proteinexpression
|
|
TN2017000354A1
(en)
|
2015-02-10 |
2019-01-16 |
Genzyme Corp |
VARIANT RNAi
|
|
CA2977355A1
(en)
|
2015-02-20 |
2016-08-25 |
University Of Iowa Research Foundation |
Methods and compositions for treating genetic eye diseases
|
|
WO2017015102A1
(en)
|
2015-07-17 |
2017-01-26 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for achieving high levels of transduction in human liver cells
|
|
BR112018003665A2
(en)
|
2015-09-28 |
2018-09-25 |
The University Of North Carolina At Chapel Hill |
methods and compositions for antibody evasion viral vectors
|
|
WO2017066764A2
(en)
|
2015-10-16 |
2017-04-20 |
William Marsh Rice University |
Modification of n-terminal region of capsid proteins for enhanced properties of adeno-associated viruses
|
|
WO2017083722A1
(en)
|
2015-11-11 |
2017-05-18 |
Greenberg Kenneth P |
Crispr compositions and methods of using the same for gene therapy
|
|
US10240145B2
(en)
|
2015-11-25 |
2019-03-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
CRISPR/Cas-mediated genome editing to treat EGFR-mutant lung cancer
|
|
KR102423442B1
(ko)
|
2015-12-11 |
2022-07-20 |
캘리포니아 인스티튜트 오브 테크놀로지 |
아데노-관련 바이러스를 지시하기 위한 타겟팅 펩타이드
|
|
JOP20190269A1
(ar)
*
|
2017-06-15 |
2019-11-20 |
Voyager Therapeutics Inc |
بولي نوكليوتيدات aadc لعلاج مرض باركنسون
|
|
EP3668980A1
(en)
|
2017-08-15 |
2020-06-24 |
Intellia Therapeutics, Inc. |
Stabilized nucleic acids encoding messenger ribonucleic acid (mrna)
|
|
CN108841868A
(zh)
*
|
2018-05-31 |
2018-11-20 |
康霖生物科技(杭州)有限公司 |
一种用于中枢神经系统疾病治疗的基因序列构建体
|
|
EP4306643A3
(en)
|
2018-10-11 |
2024-03-20 |
ethris GmbH |
Plasmid containing a sequence encoding an mrna with a segmented poly(a) tail
|
|
KR20210149251A
(ko)
*
|
2019-03-08 |
2021-12-08 |
옵시디안 테라퓨틱스, 인크. |
조율가능한 조절을 위한 인간 탄산 무수화효소 2 조성물 및 방법
|
|
CN109971729B
(zh)
*
|
2019-04-19 |
2021-07-16 |
上海信致医药科技有限公司 |
一种酶组合物
|