JPWO2022270628A1 - - Google Patents

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Publication number
JPWO2022270628A1
JPWO2022270628A1 JP2023530145A JP2023530145A JPWO2022270628A1 JP WO2022270628 A1 JPWO2022270628 A1 JP WO2022270628A1 JP 2023530145 A JP2023530145 A JP 2023530145A JP 2023530145 A JP2023530145 A JP 2023530145A JP WO2022270628 A1 JPWO2022270628 A1 JP WO2022270628A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023530145A
Other languages
Japanese (ja)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2022270628A1 publication Critical patent/JPWO2022270628A1/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2023530145A 2021-06-25 2022-06-24 Pending JPWO2022270628A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021106034 2021-06-25
PCT/JP2022/025361 WO2022270628A1 (ja) 2021-06-25 2022-06-24 Rsウイルス感染症の処置および/または予防用医薬としてのヘテロシクロアルキル置換ポリヘテロアゾール誘導体

Publications (1)

Publication Number Publication Date
JPWO2022270628A1 true JPWO2022270628A1 (https=) 2022-12-29

Family

ID=84545504

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023530145A Pending JPWO2022270628A1 (https=) 2021-06-25 2022-06-24

Country Status (7)

Country Link
US (1) US20240327392A1 (https=)
EP (1) EP4361148A4 (https=)
JP (1) JPWO2022270628A1 (https=)
CN (1) CN117730079A (https=)
AU (1) AU2022296214A1 (https=)
CA (1) CA3223875A1 (https=)
WO (1) WO2022270628A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025206404A1 (ja) * 2024-03-29 2025-10-02 国立大学法人 大分大学 線維症治療のための抗線維化化合物

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015506348A (ja) * 2011-12-22 2015-03-02 ギリアード サイエンシーズ, インコーポレイテッド 抗ウイルス剤としてのピラゾロ[1,5−a]ピリミジン
WO2015198263A2 (en) * 2014-06-26 2015-12-30 Hetero Research Foundation Novel betulinic proline substituted derivatives as hiv inhibitors
WO2016001820A1 (en) * 2014-06-30 2016-01-07 Hetero Research Foundation Novel betulinic proline imidazole derivatives as hiv inhibitors
JP2016504284A (ja) * 2012-11-16 2016-02-12 バイオクリスト ファーマスーティカルズ,インコーポレイテッドBiocryst Pharmaceuticals,Inc. 抗ウイルス性アザ糖を含有するヌクレオシド
JP2017537118A (ja) * 2014-12-08 2017-12-14 ヤンセン・サイエンシズ・アイルランド・ユーシー Rsウイルス(rsv)複製の阻害活性を有するピペリジン置換ピラゾロ[1,5−a]ピリミジン誘導体
WO2018051255A1 (en) * 2016-09-14 2018-03-22 Aurigene Discovery Technologies Limited Cyclic substituted-1,3,4-oxadiazole and thiadiazole compounds as immunomodulators
WO2018051254A1 (en) * 2016-09-14 2018-03-22 Aurigene Discovery Technologies Limited Cyclic substituted-1,2,4-oxadiazole compounds as immunomodulators

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL140040A0 (en) * 1998-06-03 2002-02-10 Guilford Pharm Inc N-linked sulfonamides of n-heterocyclic carboxylic acids or carboxylic acid isosteres
DOP2000000107A (es) * 1999-12-01 2002-09-16 Agouron Pharmaceutical Inc Compuestos, composiciones y metodos para estimular el crecimiento y alongamiento de las neuronas
US6589978B2 (en) * 2000-06-30 2003-07-08 Hoffman-La Roche Inc. 1-sulfonyl pyrrolidine derivatives
JP4221989B2 (ja) * 2002-09-30 2009-02-12 大正製薬株式会社 オキサジアゾール誘導体
JP4240978B2 (ja) * 2002-09-30 2009-03-18 大正製薬株式会社 アリールオキシメチルオキサジアゾール誘導体
JP2006523669A (ja) * 2003-03-10 2006-10-19 ファイザー・インク Nima調節タンパク質(pin1)を阻害するための、リン酸/硫酸エステル化合物および医薬組成物
EP1604989A1 (en) * 2004-06-08 2005-12-14 Santhera Pharmaceuticals (Deutschland) Aktiengesellschaft DPP-IV inhibitors
EP1981845A2 (en) * 2006-02-08 2008-10-22 Wyeth Sulfonamide derivatives to treat infection with hepatitis c virus
MX2012007420A (es) * 2009-12-24 2012-07-23 Vertex Pharma Analogos para el tratamiento o prevencion de infecciones de flavivirus.
CN102869657A (zh) * 2010-03-24 2013-01-09 沃泰克斯药物股份有限公司 用于治疗或预防黄病毒感染的类似物
US9637516B2 (en) * 2012-12-31 2017-05-02 Hetero Research Foundation Betulinic acid proline derivatives as HIV inhibitors
JP6862305B2 (ja) 2017-07-13 2021-04-21 株式会社マキタ 衣服及び報知システム
RU2712097C1 (ru) * 2018-09-28 2020-01-24 Общество с ограниченной ответственностью "Необиотек" Ингибитор дипептидилпептидазы-4 для лечения сахарного диабета 2-го типа, соединения (варианты)
JP7684282B2 (ja) * 2020-03-31 2025-05-27 田辺三菱製薬株式会社 ヒドロキシピロリジン誘導体およびその医薬用途

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015506348A (ja) * 2011-12-22 2015-03-02 ギリアード サイエンシーズ, インコーポレイテッド 抗ウイルス剤としてのピラゾロ[1,5−a]ピリミジン
JP2016504284A (ja) * 2012-11-16 2016-02-12 バイオクリスト ファーマスーティカルズ,インコーポレイテッドBiocryst Pharmaceuticals,Inc. 抗ウイルス性アザ糖を含有するヌクレオシド
WO2015198263A2 (en) * 2014-06-26 2015-12-30 Hetero Research Foundation Novel betulinic proline substituted derivatives as hiv inhibitors
WO2016001820A1 (en) * 2014-06-30 2016-01-07 Hetero Research Foundation Novel betulinic proline imidazole derivatives as hiv inhibitors
JP2017537118A (ja) * 2014-12-08 2017-12-14 ヤンセン・サイエンシズ・アイルランド・ユーシー Rsウイルス(rsv)複製の阻害活性を有するピペリジン置換ピラゾロ[1,5−a]ピリミジン誘導体
WO2018051255A1 (en) * 2016-09-14 2018-03-22 Aurigene Discovery Technologies Limited Cyclic substituted-1,3,4-oxadiazole and thiadiazole compounds as immunomodulators
WO2018051254A1 (en) * 2016-09-14 2018-03-22 Aurigene Discovery Technologies Limited Cyclic substituted-1,2,4-oxadiazole compounds as immunomodulators

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KANG, IOU-JIUN ET AL.: "A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus:", JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, JPN6022038513, 2017, pages 228 - 247, ISSN: 0005834392 *

Also Published As

Publication number Publication date
EP4361148A1 (en) 2024-05-01
EP4361148A4 (en) 2025-07-09
CA3223875A1 (en) 2022-12-29
AU2022296214A1 (en) 2024-01-25
WO2022270628A1 (ja) 2022-12-29
US20240327392A1 (en) 2024-10-03
CN117730079A (zh) 2024-03-19

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