JPWO2022256586A5 - - Google Patents
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- Publication number
- JPWO2022256586A5 JPWO2022256586A5 JP2023574119A JP2023574119A JPWO2022256586A5 JP WO2022256586 A5 JPWO2022256586 A5 JP WO2022256586A5 JP 2023574119 A JP2023574119 A JP 2023574119A JP 2023574119 A JP2023574119 A JP 2023574119A JP WO2022256586 A5 JPWO2022256586 A5 JP WO2022256586A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- alkyl
- pharma
- acceptable salt
- haloc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163196339P | 2021-06-03 | 2021-06-03 | |
| US63/196,339 | 2021-06-03 | ||
| US202163290019P | 2021-12-15 | 2021-12-15 | |
| US63/290,019 | 2021-12-15 | ||
| US202263346120P | 2022-05-26 | 2022-05-26 | |
| US63/346,120 | 2022-05-26 | ||
| PCT/US2022/032042 WO2022256586A2 (en) | 2021-06-03 | 2022-06-03 | Substituted indole compounds and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024521878A JP2024521878A (ja) | 2024-06-04 |
| JPWO2022256586A5 true JPWO2022256586A5 (enrdf_load_stackoverflow) | 2025-06-02 |
Family
ID=84323595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023574119A Pending JP2024521878A (ja) | 2021-06-03 | 2022-06-03 | 置換インドール化合物及びその使用方法 |
Country Status (18)
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112023001195A2 (pt) * | 2020-08-07 | 2023-02-28 | Shanghai Meiyue Biotech Dev Co Ltd | Composto ou racemato, estereoisômero, tautômero, composto isotopicamente rotulado, solvato, polimorfo, sal farmaceuticamente aceitável ou composto pró-fármaco do mesmo, composto, método de preparação para composto ou racemato, estereoisômero, tautômero, composto isotopicamente rotulado, solvato, polimorfo, sal farmaceuticamente aceitável ou composto de pró-fármaco, composição farmacêutica, método para tratar uma doença associada com a ativação do caminho alternativo de complemento, e, uso do composto |
| EP4273137A4 (en) * | 2020-12-30 | 2025-01-01 | S-Infinity Pharmaceuticals Co.,Ltd | SERIES OF PIPERIDINE-SUBSTITUTED BENZOIC ACID COMPOUNDS AND THEIR USE |
| EP4362933A4 (en) * | 2021-06-30 | 2025-06-04 | Apellis Pharmaceuticals, Inc. | COMPLEMENT INHIBITION |
| CA3236104A1 (en) * | 2021-10-27 | 2023-05-04 | Hugh Y. Zhu | Piperidinyl indole derivatives, preparation methods and medicinal uses thereof |
| JP2025504859A (ja) * | 2022-01-24 | 2025-02-19 | ノバルティス アーゲー | 補体因子ｂ阻害剤としてのスピロ環式ピペリジニル誘導体及びその使用 |
| CN119301114A (zh) * | 2022-06-07 | 2025-01-10 | 正大天晴药业集团股份有限公司 | 双环取代的芳香羧酸类氘代化合物 |
| CN119698414A (zh) * | 2022-06-20 | 2025-03-25 | 深圳信立泰药业股份有限公司 | 一种吲哚-苯基哌啶化合物及其制备方法与应用 |
| WO2023246870A1 (zh) * | 2022-06-23 | 2023-12-28 | 上海济煜医药科技有限公司 | 吲哚化合物的制备、应用及用途 |
| TW202423426A (zh) * | 2022-08-31 | 2024-06-16 | 美商奇努克醫療股份有限公司 | 經取代之吲哚化合物及其使用方法 |
| TW202426432A (zh) * | 2022-09-10 | 2024-07-01 | 大陸商江蘇豪森藥業集團有限公司 | ２－取代哌啶衍生物、其製備方法和醫藥用途 |
| IL320661A (en) * | 2022-11-14 | 2025-07-01 | Novartis Pharma Ag | Solid forms of complement factor B inhibitors |
| WO2024114677A1 (zh) * | 2022-11-29 | 2024-06-06 | 上海济煜医药科技有限公司 | 苯并螺环吲哚化合物的制备、应用及用途 |
| WO2024148274A1 (en) * | 2023-01-05 | 2024-07-11 | Apellis Pharmaceuticals, Inc. | Complement inhibition |
| KR20250128379A (ko) * | 2023-01-09 | 2025-08-27 | 난징 치아 타이 티안큉 파마슈티컬 컴파니 리미티드 | 보체인자 b의 억제제 |
| TW202434238A (zh) * | 2023-02-16 | 2024-09-01 | 大陸商西藏海思科製藥有限公司 | 苯並氮雜芳環衍生物的鹽、晶型及其在醫藥上的應用 |
| TW202434240A (zh) * | 2023-02-22 | 2024-09-01 | 大陸商西藏海思科製藥有限公司 | 苯並氮雜芳環衍生物的藥物組合物及其在醫藥上的應用 |
| WO2024222852A1 (zh) * | 2023-04-27 | 2024-10-31 | 上海翰森生物医药科技有限公司 | 一种哌啶基吲哚化合物的盐及其制备方法 |
| WO2025008453A1 (en) | 2023-07-04 | 2025-01-09 | Sitala Bio Ltd | 2-(1h-indol-4-yl)methyl)-isoindoline derivatives as factor b inhibitors |
| WO2025008451A1 (en) | 2023-07-04 | 2025-01-09 | Sitala Bio Ltd | 2-(1h-indol-4-yl)methyl)2h-indazole derivatives as factor b inhibitors |
| WO2025008516A2 (en) | 2023-07-06 | 2025-01-09 | Sitala Bio Ltd | Novel compounds |
| WO2025008517A1 (en) | 2023-07-06 | 2025-01-09 | Sitala Bio Ltd | Indole derivatives with factor b inhibitory activity |
| CN119371402A (zh) * | 2023-07-26 | 2025-01-28 | 上海美悦生物科技发展有限公司 | 螺环烯基类或氮杂烯基类化合物及其药物组合物、制备方法和用途 |
| WO2025061083A1 (zh) * | 2023-09-20 | 2025-03-27 | 上海美悦生物科技发展有限公司 | 杂环化合物在制备预防和/或治疗肾脏疾病的药物中的用途 |
| WO2025119266A1 (zh) * | 2023-12-05 | 2025-06-12 | 西藏海思科制药有限公司 | 苯并氮杂芳环衍生物在治疗补体因子b介导的疾病中的用途 |
| WO2025172535A1 (en) | 2024-02-15 | 2025-08-21 | Sitala Bio Ltd | Indole and benzimidazole compounds as factor b inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9468661B2 (en) * | 2012-06-28 | 2016-10-18 | Novartis Ag | Pyrrolidine derivatives and their use as complement pathway modulators |
| JO3425B1 (ar) * | 2013-07-15 | 2019-10-20 | Novartis Ag | مشتقات البابيريدينيل-اندول واستخدامها كعامل متمم لمثبطات b |
| JP7057290B2 (ja) * | 2016-06-27 | 2022-04-19 | アキリオン ファーマシューティカルズ，インコーポレーテッド | 医学的障害を治療するためのキナゾリン及びインドール化合物 |
| BR112023001195A2 (pt) * | 2020-08-07 | 2023-02-28 | Shanghai Meiyue Biotech Dev Co Ltd | Composto ou racemato, estereoisômero, tautômero, composto isotopicamente rotulado, solvato, polimorfo, sal farmaceuticamente aceitável ou composto pró-fármaco do mesmo, composto, método de preparação para composto ou racemato, estereoisômero, tautômero, composto isotopicamente rotulado, solvato, polimorfo, sal farmaceuticamente aceitável ou composto de pró-fármaco, composição farmacêutica, método para tratar uma doença associada com a ativação do caminho alternativo de complemento, e, uso do composto |
| CA3236104A1 (en) * | 2021-10-27 | 2023-05-04 | Hugh Y. Zhu | Piperidinyl indole derivatives, preparation methods and medicinal uses thereof |
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2022
- 2022-06-03 IL IL308835A patent/IL308835A/en unknown
- 2022-06-03 AU AU2022283903A patent/AU2022283903A1/en active Pending
- 2022-06-03 KR KR1020237045081A patent/KR20240017004A/ko active Pending
- 2022-06-03 BR BR112023025235A patent/BR112023025235A2/pt unknown
- 2022-06-03 CA CA3222144A patent/CA3222144A1/en active Pending
- 2022-06-03 PH PH1/2023/553130A patent/PH12023553130A1/en unknown
- 2022-06-03 PE PE2023003178A patent/PE20250114A1/es unknown
- 2022-06-03 JP JP2023574119A patent/JP2024521878A/ja active Pending
- 2022-06-03 CN CN202510248844.6A patent/CN120081822A/zh active Pending
- 2022-06-03 CR CR20230564A patent/CR20230564A/es unknown
- 2022-06-03 EP EP22816892.8A patent/EP4346812A4/en active Pending
- 2022-06-03 MX MX2023014274A patent/MX2023014274A/es unknown
- 2022-06-03 WO PCT/US2022/032042 patent/WO2022256586A2/en active Application Filing
- 2022-06-03 US US18/566,259 patent/US20240287034A1/en active Pending
-
2023
- 2023-11-30 CO CONC2023/0016557A patent/CO2023016557A2/es unknown
- 2023-11-30 DO DO2023000263A patent/DOP2023000263A/es unknown
- 2023-11-30 EC ECSENADI202390260A patent/ECSP23090260A/es unknown
- 2023-11-30 CL CL2023003591A patent/CL2023003591A1/es unknown