JPWO2022130342A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2022130342A5
JPWO2022130342A5 JP2023537572A JP2023537572A JPWO2022130342A5 JP WO2022130342 A5 JPWO2022130342 A5 JP WO2022130342A5 JP 2023537572 A JP2023537572 A JP 2023537572A JP 2023537572 A JP2023537572 A JP 2023537572A JP WO2022130342 A5 JPWO2022130342 A5 JP WO2022130342A5
Authority
JP
Japan
Prior art keywords
seq
heavy chain
chain monomer
amino acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023537572A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023554500A (ja
JP7778148B2 (ja
JP2023554500A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2021/061972 external-priority patent/WO2022130342A1/en
Publication of JP2023554500A publication Critical patent/JP2023554500A/ja
Publication of JP2023554500A5 publication Critical patent/JP2023554500A5/ja
Publication of JPWO2022130342A5 publication Critical patent/JPWO2022130342A5/ja
Priority to JP2025197132A priority Critical patent/JP2026041774A/ja
Application granted granted Critical
Publication of JP7778148B2 publication Critical patent/JP7778148B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023537572A 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用 Active JP7778148B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025197132A JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063127408P 2020-12-18 2020-12-18
US63/127,408 2020-12-18
PCT/IB2021/061972 WO2022130342A1 (en) 2020-12-18 2021-12-17 Tetravalent fzd and wnt co-receptor binding antibody molecules and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025197132A Division JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Publications (4)

Publication Number Publication Date
JP2023554500A JP2023554500A (ja) 2023-12-27
JP2023554500A5 JP2023554500A5 (https=) 2025-05-20
JPWO2022130342A5 true JPWO2022130342A5 (https=) 2025-05-20
JP7778148B2 JP7778148B2 (ja) 2025-12-01

Family

ID=82058983

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2023537572A Active JP7778148B2 (ja) 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用
JP2023537540A Pending JP2024500839A (ja) 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用
JP2025197132A Pending JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023537540A Pending JP2024500839A (ja) 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用
JP2025197132A Pending JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Country Status (11)

Country Link
US (3) US20250270332A1 (https=)
EP (3) EP4263617A4 (https=)
JP (3) JP7778148B2 (https=)
KR (1) KR20230122077A (https=)
CN (2) CN116917332A (https=)
AU (2) AU2021399278A1 (https=)
CA (2) CA3204321A1 (https=)
CL (2) CL2023001768A1 (https=)
IL (2) IL303344A (https=)
MX (1) MX2023007103A (https=)
WO (2) WO2022130342A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3732201A4 (en) 2017-12-19 2022-04-20 Surrozen Operating, Inc. WNT SURROGATES AND THEIR USES
CN120025448A (zh) * 2019-06-11 2025-05-23 安托拉诊疗公司 多价fzd和wnt结合分子及其用途
WO2023250402A2 (en) * 2022-06-22 2023-12-28 Antlera Therapeutics Inc. Tetravalent fzd and wnt co-receptor binding antibody molecules and uses thereof
WO2023130055A2 (en) * 2021-12-31 2023-07-06 Surrozen Operating, Inc. Wnt receptor-specific compound and method relating thereto
WO2024007008A2 (en) * 2022-06-30 2024-01-04 The University Of Chicago Cd73 (nt5e) targeting polypeptides
WO2024227103A1 (en) * 2023-04-27 2024-10-31 Surrozen Operating, Inc. Molecules modulating wnt signaling pathways and uses thereof
WO2025019458A2 (en) * 2023-07-14 2025-01-23 The Trustees Of Columbia University In The City Of New York Specific blood retinal barrier defect in glaucoma directs new treatments and clinical tests
WO2025168716A1 (en) 2024-02-07 2025-08-14 Eyebiotech Limited Compositions, doses, and methods for treatment of ocular diseases
WO2025176847A1 (en) 2024-02-21 2025-08-28 Ags Therapeutics Sas Ocular delivery of active agents via microalgae extracellular vesicles
US20260092125A1 (en) * 2024-09-06 2026-04-02 Eyebiotech Limited Multivalent fzd4, wnt co-receptor, and vegf binding molecules and uses thereof
WO2026055312A1 (en) * 2024-09-06 2026-03-12 Merck Sharp & Dohme Llc Multivalent fzd4, wnt co-receptor, and vegf receptor molecules and uses thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2405246A1 (en) 1990-12-03 1992-06-11 Genentech, Inc. Enrichment method for variant proteins with alterred binding properties
AU784983B2 (en) 1999-12-15 2006-08-17 Genentech Inc. Shotgun scanning, a combinatorial method for mapping functional protein epitopes
EP1513879B1 (en) 2002-06-03 2018-08-22 Genentech, Inc. Synthetic antibody phage libraries
CA2510003A1 (en) 2003-01-16 2004-08-05 Genentech, Inc. Synthetic antibody phage libraries
US7785903B2 (en) 2004-04-09 2010-08-31 Genentech, Inc. Variable domain library and uses
EP1957531B1 (en) 2005-11-07 2016-04-13 Genentech, Inc. Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
WO2007064919A2 (en) 2005-12-02 2007-06-07 Genentech, Inc. Binding polypeptides with restricted diversity sequences
JP2009536527A (ja) 2006-05-09 2009-10-15 ジェネンテック・インコーポレーテッド 最適化されたスキャフォールドを備えた結合ポリペプチド
CN100592373C (zh) 2007-05-25 2010-02-24 群康科技(深圳)有限公司 液晶显示面板驱动装置及其驱动方法
CN103002911B (zh) 2008-09-26 2015-08-26 昂考梅德药品有限公司 卷曲蛋白结合药剂及其应用
EP2804629A1 (en) 2012-01-18 2014-11-26 Genentech, Inc. Anti-lrp5 antibodies and methods of use
DE102012202081A1 (de) 2012-02-13 2013-08-14 Osram Gmbh Glühfaden für elektrische lampen und elektrische lampe sowie herstellungsverfahren für einen glühfaden
AU2014246658B2 (en) 2013-04-03 2018-10-04 Peter Maccallum Cancer Institute Antibodies against human RYK and uses therefor
US9237411B2 (en) 2013-07-25 2016-01-12 Elwha Llc Systems and methods for providing one or more functionalities to a wearable computing device with directional antenna
EP3033356B1 (en) 2013-08-14 2020-01-15 Sachdev Sidhu Antibodies against frizzled proteins and methods of use thereof
JP6865688B2 (ja) 2015-01-16 2021-04-28 ジュノー セラピューティクス インコーポレイテッド Ror1に特異的な抗体およびキメラ抗原受容体
US10919968B2 (en) 2016-01-29 2021-02-16 Modmab Therapeutics Corporation Frizzled5 protein-binding agents
WO2018026942A1 (en) 2016-08-02 2018-02-08 Merrimack Pharmaceuticals, Inc. Heteromeric polypeptides
US11039659B2 (en) 2017-09-07 2021-06-22 Nike, Inc. Sole structure for article of footwear
US20210032352A1 (en) 2018-02-14 2021-02-04 Antera Therapeutics Inc. Multivalent Binding Molecules Activating WNT Signaling and Uses Thereof
CA3104526A1 (en) * 2018-07-05 2020-01-09 Surrozen, Inc. Multi-specific wnt surrogate molecules and uses thereof
US10671121B2 (en) 2018-09-14 2020-06-02 Apple Inc. Magnetic layout in electronic devices and accessory devices for electronic devices
CN120025448A (zh) * 2019-06-11 2025-05-23 安托拉诊疗公司 多价fzd和wnt结合分子及其用途

Similar Documents

Publication Publication Date Title
WO2022130342A4 (en) Tetravalent fzd and wnt co-receptor binding antibody molecules and uses thereof
US12398204B2 (en) Method of treating an ocular condition by administering multispecific antibodies that activates TIE2 and binds a receptor tyrosine kinase agonist
JP2020196744A5 (https=)
JP6742245B2 (ja) 多重特異性抗体
TWI803876B (zh) 具有交叉結合區定向之雙重可變區類抗體結合蛋白
JP2023085476A5 (https=)
JP2019533441A5 (https=)
JP2021533779A5 (https=)
JP2018537966A5 (https=)
IL292780A (en) A new 4-1bbl trimer containing antigen-binding molecules
JP2017537896A5 (https=)
JP2021507698A5 (https=)
JPWO2022130342A5 (https=)
JP7657591B2 (ja) 二重特異性抗原結合コンストラクト
JP2025160226A5 (https=)
JP2025124718A5 (https=)
JPWO2021076564A5 (https=)
JPWO2020037150A5 (https=)
JPWO2022102768A5 (https=)
JPWO2022042488A5 (https=)
JPWO2023045977A5 (https=)
JPWO2022241082A5 (https=)
JPWO2023056252A5 (https=)
JP2025527160A (ja) 多重特異性抗体およびその使用
JPWO2021148006A5 (https=)