JPWO2022102695A5 - - Google Patents
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- Publication number
- JPWO2022102695A5 JPWO2022102695A5 JP2022561984A JP2022561984A JPWO2022102695A5 JP WO2022102695 A5 JPWO2022102695 A5 JP WO2022102695A5 JP 2022561984 A JP2022561984 A JP 2022561984A JP 2022561984 A JP2022561984 A JP 2022561984A JP WO2022102695 A5 JPWO2022102695 A5 JP WO2022102695A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- set forth
- sequence set
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims 56
- 150000001413 amino acids Chemical class 0.000 claims 56
- 239000003814 drug Substances 0.000 claims 22
- 229940124597 therapeutic agent Drugs 0.000 claims 16
- 239000000611 antibody drug conjugate Substances 0.000 claims 6
- 229940049595 antibody-drug conjugate Drugs 0.000 claims 6
- 229940079593 drug Drugs 0.000 claims 6
- 206010027406 Mesothelioma Diseases 0.000 claims 5
- 206010035603 Pleural mesothelioma Diseases 0.000 claims 3
- 201000002513 peritoneal mesothelioma Diseases 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
- 208000024407 malignant pericardial mesothelioma Diseases 0.000 claims 1
- 201000004266 pericardial mesothelioma Diseases 0.000 claims 1
- 210000001550 testis Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020188910 | 2020-11-12 | ||
| PCT/JP2021/041496 WO2022102695A1 (ja) | 2020-11-12 | 2021-11-11 | 抗ｂ７－ｈ３抗体－薬物コンジュゲート投与による中皮腫の治療 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2022102695A1 JPWO2022102695A1 (https=) | 2022-05-19 |
| JPWO2022102695A5 true JPWO2022102695A5 (https=) | 2024-11-15 |
Family
ID=81601304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022561984A Pending JPWO2022102695A1 (https=) | 2020-11-12 | 2021-11-11 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230398230A1 (https=) |
| EP (1) | EP4245322A4 (https=) |
| JP (1) | JPWO2022102695A1 (https=) |
| KR (1) | KR20230107239A (https=) |
| CN (1) | CN116615250A (https=) |
| CA (1) | CA3198382A1 (https=) |
| TW (1) | TW202233249A (https=) |
| WO (1) | WO2022102695A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024114318A1 (zh) * | 2022-11-29 | 2024-06-06 | 四川科伦博泰生物医药股份有限公司 | 药物连接子化合物及其制备方法和用途 |
| AR131524A1 (es) * | 2022-12-29 | 2025-03-26 | Beigene Ltd | Conjugados de anticuerpos-fármacos b7h3 |
| AU2024218327A1 (en) | 2023-02-09 | 2025-09-25 | Beone Medicines I Gmbh | Self-stabilizing linker conjugates |
| CN120957753A (zh) | 2023-03-23 | 2025-11-14 | 广州百济神州生物制药有限公司 | 生物活性结合物、其制备方法和其用途 |
| JPWO2024214685A1 (https=) * | 2023-04-10 | 2024-10-17 | ||
| AR133125A1 (es) | 2023-06-29 | 2025-08-27 | Beigene Switzerland Gmbh | Conjugados bioactivos, método de preparación y uso de estos |
| CN121568721A (zh) | 2023-06-29 | 2026-02-24 | 广州百济神州生物制药有限公司 | 生物活性缀合物、其制备方法和其用途 |
| CN119454937A (zh) * | 2023-11-13 | 2025-02-18 | 苏州宜联生物医药有限公司 | 抗b7h3抗体-药物偶联物治疗癌症的方法 |
| WO2025131054A1 (en) * | 2023-12-22 | 2025-06-26 | Innovent Biologics (Suzhou) Co., Ltd. | Antibody drug conjugates targeting to b7-h3 and egfr and the use thereof |
| CN121130102A (zh) * | 2024-06-14 | 2025-12-16 | 长春金赛药业有限责任公司 | 靶向b7-h3和psma的双特异性抗体及抗体-药物偶联物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| DK1071700T3 (da) | 1998-04-20 | 2010-06-07 | Glycart Biotechnology Ag | Glykosylerings-modifikation af antistoffer til forbedring af antistofafhængig cellulær cytotoksicitet |
| CA2704600C (en) | 1999-04-09 | 2016-10-25 | Kyowa Kirin Co., Ltd. | A method for producing antibodies with increased adcc activity |
| CA2953239A1 (en) | 2000-10-06 | 2002-04-18 | Kyowa Hakko Kirin Co., Ltd. | Antibody composition-producing cell |
| EP1923192A4 (en) | 2005-07-29 | 2010-09-15 | Doshisha | METHOD FOR FORMING FIBER-REINFORCED THERMOPLASTIC COMPOSITE MATERIAL, INTERMEDIATE MATERIAL AND COMPOSITE SURFACE IMPORTS |
| IN2014DN06806A (https=) | 2012-02-10 | 2015-05-22 | Univ Maryland | |
| ES2773710T3 (es) * | 2012-10-11 | 2020-07-14 | Daiichi Sankyo Co Ltd | Enlazadores para conjugados de anticuerpo - fármaco |
| AU2014371934B2 (en) | 2013-12-25 | 2020-01-23 | Daiichi Sankyo Company, Limited | Anti-TROP2 antibody-drug conjugate |
| IL310627B2 (en) | 2014-01-31 | 2026-04-01 | Daiichi Sankyo Co Ltd | Anti-HER2 antibody-drug conjugates, compositions containing them and uses thereof |
| KR102445502B1 (ko) | 2014-04-10 | 2022-09-21 | 다이이찌 산쿄 가부시키가이샤 | 항her3 항체-약물 콘주게이트 |
| CN116059395A (zh) | 2015-06-29 | 2023-05-05 | 第一三共株式会社 | 用于选择性制造抗体-药物缀合物的方法 |
| CN108699159B (zh) * | 2016-02-15 | 2022-07-29 | 地方独立行政法人神奈川县立病院机构 | 膜型粘蛋白样蛋白质的识别及其医疗应用 |
| GEP20227398B (en) * | 2016-04-15 | 2022-07-25 | Macrogenics Inc | Novel b7-h3 binding molecules, antibody drug conjugates thereof and usage thereof |
| AU2018320470B2 (en) * | 2017-08-23 | 2025-04-24 | Daiichi Sankyo Company, Limited | Antibody-drug conjugate preparation and lyophilization for same |
| IL324591A (en) | 2017-08-31 | 2026-01-01 | Daiichi Sankyo Co Ltd | Improved antibody-drug conjugate production methods |
-
2021
- 2021-11-11 CN CN202180076478.0A patent/CN116615250A/zh active Pending
- 2021-11-11 US US18/036,290 patent/US20230398230A1/en active Pending
- 2021-11-11 KR KR1020237015764A patent/KR20230107239A/ko active Pending
- 2021-11-11 JP JP2022561984A patent/JPWO2022102695A1/ja active Pending
- 2021-11-11 TW TW110141987A patent/TW202233249A/zh unknown
- 2021-11-11 EP EP21891940.5A patent/EP4245322A4/en active Pending
- 2021-11-11 CA CA3198382A patent/CA3198382A1/en active Pending
- 2021-11-11 WO PCT/JP2021/041496 patent/WO2022102695A1/ja not_active Ceased
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