JPWO2021241523A1 - - Google Patents
Info
- Publication number
- JPWO2021241523A1 JPWO2021241523A1 JP2022526545A JP2022526545A JPWO2021241523A1 JP WO2021241523 A1 JPWO2021241523 A1 JP WO2021241523A1 JP 2022526545 A JP2022526545 A JP 2022526545A JP 2022526545 A JP2022526545 A JP 2022526545A JP WO2021241523 A1 JPWO2021241523 A1 JP WO2021241523A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020090526 | 2020-05-25 | ||
| JP2020090526 | 2020-05-25 | ||
| PCT/JP2021/019676 WO2021241523A1 (ja) | 2020-05-25 | 2021-05-24 | Th2介在性疾患を治療または予防するためのPD-1アゴニスト含有医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2021241523A1 true JPWO2021241523A1 (https=) | 2021-12-02 |
| JP7754455B2 JP7754455B2 (ja) | 2025-10-15 |
Family
ID=78744780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022526545A Active JP7754455B2 (ja) | 2020-05-25 | 2021-05-24 | Th2介在性疾患を治療または予防するためのPD-1アゴニスト含有医薬組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230183347A1 (https=) |
| EP (1) | EP4159235A4 (https=) |
| JP (1) | JP7754455B2 (https=) |
| KR (1) | KR20230015348A (https=) |
| CN (1) | CN115697405A (https=) |
| TW (1) | TWI890796B (https=) |
| WO (1) | WO2021241523A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CR20220596A (es) | 2020-05-26 | 2023-01-23 | Boehringer Ingelheim Int | Anticuerpos anti-pd-1 |
| WO2022239820A1 (ja) * | 2021-05-13 | 2022-11-17 | 公益財団法人神戸医療産業都市推進機構 | 炎症性疾患を治療又は予防するための抗ヒトpd-1アゴニスト抗体及びこれを含有する医薬組成物 |
| KR20240137086A (ko) * | 2022-01-28 | 2024-09-19 | 조지아뮨 인코포레이티드 | Pd-1 작용제인 세포예정사 단백질 1에 대한 항체 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013022091A1 (ja) * | 2011-08-11 | 2013-02-14 | 小野薬品工業株式会社 | Pd-1アゴニストからなる自己免疫疾患治療剤 |
| CN106924718A (zh) * | 2017-04-27 | 2017-07-07 | 中山大学 | B7‑dc突变体在治疗哮喘中的应用 |
| CN107149680A (zh) * | 2017-04-27 | 2017-09-12 | 中山大学 | Pd‑1h激动剂在哮喘治疗中的应用 |
| WO2019168745A1 (en) * | 2018-03-02 | 2019-09-06 | Eli Lilly And Company | Pd-1 agonist antibodies and uses thereof |
| JP2019531284A (ja) * | 2016-09-19 | 2019-10-31 | セルジーン コーポレイション | Pd−1結合タンパク質を使用して免疫障害を治療する方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105142672B (zh) | 2012-10-23 | 2019-04-05 | 西纳福克斯股份有限公司 | 经修饰的抗体、抗体-缀合物及其制备方法 |
| CN107149530A (zh) * | 2016-03-04 | 2017-09-12 | 吴东 | 一种洗头装置 |
| WO2022239820A1 (ja) * | 2021-05-13 | 2022-11-17 | 公益財団法人神戸医療産業都市推進機構 | 炎症性疾患を治療又は予防するための抗ヒトpd-1アゴニスト抗体及びこれを含有する医薬組成物 |
-
2021
- 2021-05-24 US US17/923,996 patent/US20230183347A1/en active Pending
- 2021-05-24 WO PCT/JP2021/019676 patent/WO2021241523A1/ja not_active Ceased
- 2021-05-24 CN CN202180037220.XA patent/CN115697405A/zh active Pending
- 2021-05-24 KR KR1020227040648A patent/KR20230015348A/ko active Pending
- 2021-05-24 EP EP21811909.7A patent/EP4159235A4/en active Pending
- 2021-05-24 JP JP2022526545A patent/JP7754455B2/ja active Active
- 2021-05-25 TW TW110118921A patent/TWI890796B/zh active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013022091A1 (ja) * | 2011-08-11 | 2013-02-14 | 小野薬品工業株式会社 | Pd-1アゴニストからなる自己免疫疾患治療剤 |
| JP2019531284A (ja) * | 2016-09-19 | 2019-10-31 | セルジーン コーポレイション | Pd−1結合タンパク質を使用して免疫障害を治療する方法 |
| CN106924718A (zh) * | 2017-04-27 | 2017-07-07 | 中山大学 | B7‑dc突变体在治疗哮喘中的应用 |
| CN107149680A (zh) * | 2017-04-27 | 2017-09-12 | 中山大学 | Pd‑1h激动剂在哮喘治疗中的应用 |
| WO2019168745A1 (en) * | 2018-03-02 | 2019-09-06 | Eli Lilly And Company | Pd-1 agonist antibodies and uses thereof |
Non-Patent Citations (5)
| Title |
|---|
| CUREUS, vol. vol.9, issue 4, JPN6025014164, 2017, pages 1177 - 1, ISSN: 0005569211 * |
| GUT, vol. vol.64, issue 2, JPN6025014163, 2015, pages 260 - 271, ISSN: 0005569210 * |
| LEWKOWICH, IP., ET AL.: "PD-L2 modulates asthma severity by directly decreasing dendritic cell IL-12 production", MUCOSAL IMMUNOL., vol. 6, no. 4, JPN6021027453, 2013, pages 728 - 739, ISSN: 0005569209 * |
| MCALEES, J.W., ET AL.: "Differential control of CD4+ T-cell subsets by the PD-1/PD-L1 axis in a mouse model of allergic asth", EUR. J. IMMUNOL., vol. vol.45, issue 4, JPN6021027455, 2015, pages 1019 - 1029, ISSN: 0005569208 * |
| OFLAZOGLU, E., ET AL.: "Paradoxical role of programmed death-1 ligand 2 in Th2 immune responses in vitro and in a mouse asth", EUR. J. IMMUNOL., vol. vol.34, issue 12, JPN6021027457, 2004, pages 3326 - 3336, ISSN: 0005569207 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20230183347A1 (en) | 2023-06-15 |
| TW202210099A (zh) | 2022-03-16 |
| CN115697405A (zh) | 2023-02-03 |
| EP4159235A1 (en) | 2023-04-05 |
| TWI890796B (zh) | 2025-07-21 |
| KR20230015348A (ko) | 2023-01-31 |
| EP4159235A4 (en) | 2024-07-10 |
| JP7754455B2 (ja) | 2025-10-15 |
| WO2021241523A1 (ja) | 2021-12-02 |
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