JPWO2021231655A5 - - Google Patents

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Publication number
JPWO2021231655A5
JPWO2021231655A5 JP2022568746A JP2022568746A JPWO2021231655A5 JP WO2021231655 A5 JPWO2021231655 A5 JP WO2021231655A5 JP 2022568746 A JP2022568746 A JP 2022568746A JP 2022568746 A JP2022568746 A JP 2022568746A JP WO2021231655 A5 JPWO2021231655 A5 JP WO2021231655A5
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JP
Japan
Prior art keywords
spacer
seq
acid sequence
amino acid
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022568746A
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English (en)
Japanese (ja)
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JP2023526234A5 (https=
JP2023526234A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/032098 external-priority patent/WO2021231655A1/en
Publication of JP2023526234A publication Critical patent/JP2023526234A/ja
Publication of JPWO2021231655A5 publication Critical patent/JPWO2021231655A5/ja
Publication of JP2023526234A5 publication Critical patent/JP2023526234A5/ja
Pending legal-status Critical Current

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JP2022568746A 2020-05-12 2021-05-12 キメラ抗原受容体スペーサー Pending JP2023526234A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063023751P 2020-05-12 2020-05-12
US63/023,751 2020-05-12
PCT/US2021/032098 WO2021231655A1 (en) 2020-05-12 2021-05-12 Chimeric antigen receptor spacers

Publications (3)

Publication Number Publication Date
JP2023526234A JP2023526234A (ja) 2023-06-21
JPWO2021231655A5 true JPWO2021231655A5 (https=) 2024-07-31
JP2023526234A5 JP2023526234A5 (https=) 2024-07-31

Family

ID=76250478

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022568746A Pending JP2023526234A (ja) 2020-05-12 2021-05-12 キメラ抗原受容体スペーサー

Country Status (11)

Country Link
US (2) US20210380658A1 (https=)
EP (1) EP4149968A1 (https=)
JP (1) JP2023526234A (https=)
KR (1) KR20230022411A (https=)
CN (1) CN116096739A (https=)
AU (1) AU2021270299A1 (https=)
BR (1) BR112022022953A2 (https=)
CA (1) CA3157427A1 (https=)
IL (1) IL298114A (https=)
MX (1) MX2022014203A (https=)
WO (1) WO2021231655A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL296511A (en) 2020-03-20 2022-11-01 Lyell Immunopharma Inc Novel recombinant cell surface markers
AU2022227686A1 (en) 2021-02-25 2023-07-27 Lyell Immunopharma, Inc. Ror1 targeting chimeric antigen receptor
AU2022384253A1 (en) * 2021-11-10 2024-05-30 Outpace Bio, Inc. Chimeric antigen receptors
CN115724986B (zh) * 2022-07-11 2024-07-19 惠和生物技术(上海)有限公司 三特异性抗体及其用途

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
EP1958962A3 (en) 1997-06-12 2013-05-01 Novartis International Pharmaceutical Ltd. Artificial antibody polypeptides
CN1294148C (zh) 2001-04-11 2007-01-10 中国科学院遗传与发育生物学研究所 环状单链三特异抗体
KR20060041205A (ko) 2003-07-01 2006-05-11 이뮤노메딕스, 인코오포레이티드 양특이성 항체들의 다가 담체들
JP2008512352A (ja) 2004-07-17 2008-04-24 イムクローン システムズ インコーポレイティド 新規な四価の二重特異性抗体
KR20130108481A (ko) 2005-08-19 2013-10-02 아보트 러보러터리즈 이원 가변 도메인 면역글로불린 및 이의 용도
WO2007085814A1 (en) * 2006-01-24 2007-08-02 Domantis Limited Fusion proteins that contain natural junctions
WO2010124188A1 (en) 2009-04-23 2010-10-28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-human ror1 antibodies
US9758586B2 (en) 2010-12-01 2017-09-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Chimeric rabbit/human ROR1 antibodies
GB201203071D0 (en) * 2012-02-22 2012-04-04 Ucb Pharma Sa Biological products
CA2881981A1 (en) * 2012-08-20 2014-02-27 Fred Hutchinson Cancer Research Center Method and compositions for cellular immunotherapy
US20160333108A1 (en) * 2014-01-13 2016-11-17 Stephen J. Forman CHIMERIC ANTIGEN RECEPTORS (CARs) HAVING MUTATIONS IN THE FC SPACER REGION AND METHODS FOR THEIR USE
KR102048855B1 (ko) * 2014-07-29 2019-11-26 셀렉티스 암 면역요법을 위한 ror1(ntrkr1) 특이적 키메라 항원 수용체
JP6865688B2 (ja) * 2015-01-16 2021-04-28 ジュノー セラピューティクス インコーポレイテッド Ror1に特異的な抗体およびキメラ抗原受容体
GB201803079D0 (en) * 2018-02-26 2018-04-11 Autolus Ltd Cell
WO2019178078A1 (en) * 2018-03-14 2019-09-19 Seattle Children's Hospital (dba Seattle Children's Research Institute) Il-13 receptor alpha 2 (il13ra2) chimeric antigen receptor for tumor specific t cell immunotherapy
WO2019197676A1 (en) * 2018-04-13 2019-10-17 Ludwig Institute For Cancer Research Ltd Heterodimeric inactivatable chimeric antigen receptors
US20210121466A1 (en) * 2018-05-03 2021-04-29 Juno Therapeutics, Inc. Combination therapy of a chimeric antigen receptor (car) t cell therapy and a kinase inhibitor
EP3807317A4 (en) * 2018-06-15 2022-03-30 The Regents of University of California CHIMERIC FUSION FRAGMENT ANTIGEN RECEPTORS AND USES THEREOF
WO2020167957A1 (en) * 2019-02-12 2020-08-20 Board Of Regents, The University Of Texas System High affinity engineered t-cell receptors targeting cmv infected cells
CN114222763A (zh) * 2019-06-19 2022-03-22 尤利乌斯·马克西米利安维尔茨堡大学 在嵌合抗原受体设计中实现的超模块化IgG3间隔区结构域和多功能位点

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