JPWO2021230131A5 - - Google Patents
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- Publication number
- JPWO2021230131A5 JPWO2021230131A5 JP2022521858A JP2022521858A JPWO2021230131A5 JP WO2021230131 A5 JPWO2021230131 A5 JP WO2021230131A5 JP 2022521858 A JP2022521858 A JP 2022521858A JP 2022521858 A JP2022521858 A JP 2022521858A JP WO2021230131 A5 JPWO2021230131 A5 JP WO2021230131A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- dose
- active ingredient
- dementia
- cilostazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000004480 active ingredient Substances 0.000 claims 4
- 206010012289 Dementia Diseases 0.000 claims 3
- RRGUKTPIGVIEKM-UHFFFAOYSA-N cilostazol Chemical compound C=1C=C2NC(=O)CCC2=CC=1OCCCCC1=NN=NN1C1CCCCC1 RRGUKTPIGVIEKM-UHFFFAOYSA-N 0.000 claims 3
- 229960004588 cilostazol Drugs 0.000 claims 3
- 208000010877 cognitive disease Diseases 0.000 claims 3
- 208000027061 mild cognitive impairment Diseases 0.000 claims 3
- KFXNZXLUGHLDBB-UHFFFAOYSA-N 6-[4-[1-(4-hydroxycyclohexyl)tetrazol-5-yl]butoxy]-3,4-dihydro-1h-quinolin-2-one Chemical compound C1CC(O)CCC1N1C(CCCCOC=2C=C3CCC(=O)NC3=CC=2)=NN=N1 KFXNZXLUGHLDBB-UHFFFAOYSA-N 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- GHALECSGOJQOHW-UHFFFAOYSA-N 6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-1h-quinolin-2-one Chemical compound C=1C=C2NC(=O)C=CC2=CC=1OCCCCC1=NN=NN1C1CCCCC1 GHALECSGOJQOHW-UHFFFAOYSA-N 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024189461A JP2025010627A (ja) | 2020-05-11 | 2024-10-29 | 軽度認知障害治療剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020083163 | 2020-05-11 | ||
| JP2020083163 | 2020-05-11 | ||
| PCT/JP2021/017368 WO2021230131A1 (ja) | 2020-05-11 | 2021-05-06 | 軽度認知障害治療剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024189461A Division JP2025010627A (ja) | 2020-05-11 | 2024-10-29 | 軽度認知障害治療剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2021230131A1 JPWO2021230131A1 (https=) | 2021-11-18 |
| JPWO2021230131A5 true JPWO2021230131A5 (https=) | 2023-04-12 |
| JP7587218B2 JP7587218B2 (ja) | 2024-11-20 |
Family
ID=78525720
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022521858A Active JP7587218B2 (ja) | 2020-05-11 | 2021-05-06 | 軽度認知障害治療剤 |
| JP2024189461A Pending JP2025010627A (ja) | 2020-05-11 | 2024-10-29 | 軽度認知障害治療剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024189461A Pending JP2025010627A (ja) | 2020-05-11 | 2024-10-29 | 軽度認知障害治療剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230270737A1 (https=) |
| EP (1) | EP4151213A4 (https=) |
| JP (2) | JP7587218B2 (https=) |
| CN (1) | CN115551508A (https=) |
| WO (1) | WO2021230131A1 (https=) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI323660B (en) * | 2003-02-25 | 2010-04-21 | Otsuka Pharma Co Ltd | Pten inhibitor or maxi-k channels opener |
| WO2009133128A1 (en) * | 2008-04-29 | 2009-11-05 | Pharnext | Combination compositions for treating alzheimer disease and related disorders with zonisamide and acamprosate |
| KR20120010800A (ko) * | 2010-07-27 | 2012-02-06 | 인제대학교 산학협력단 | 실로스타졸 또는 이의 약리학적 허용가능한 염을 유효성분으로 함유하는 퇴행성 신경질환 치료 및 예방용 약학조성물 |
| RU2015101100A (ru) * | 2012-06-15 | 2016-08-10 | Фаундейшн Фор Байомедикал Рисерч Энд Инновейшн | Профилактическое и/или терапевтическое средство для умеренного когнитивного нарушения |
| CN108430474A (zh) * | 2015-12-25 | 2018-08-21 | 大塚制药株式会社 | 包含阿立哌唑和西洛他唑的药物 |
-
2021
- 2021-05-06 WO PCT/JP2021/017368 patent/WO2021230131A1/ja not_active Ceased
- 2021-05-06 EP EP21805235.5A patent/EP4151213A4/en active Pending
- 2021-05-06 JP JP2022521858A patent/JP7587218B2/ja active Active
- 2021-05-06 CN CN202180034439.4A patent/CN115551508A/zh active Pending
- 2021-05-06 US US17/924,447 patent/US20230270737A1/en active Pending
-
2024
- 2024-10-29 JP JP2024189461A patent/JP2025010627A/ja active Pending
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