JPWO2021221995A5 - - Google Patents
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- Publication number
- JPWO2021221995A5 JPWO2021221995A5 JP2022566010A JP2022566010A JPWO2021221995A5 JP WO2021221995 A5 JPWO2021221995 A5 JP WO2021221995A5 JP 2022566010 A JP2022566010 A JP 2022566010A JP 2022566010 A JP2022566010 A JP 2022566010A JP WO2021221995 A5 JPWO2021221995 A5 JP WO2021221995A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleic acid
- acid sequence
- vector
- capsid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063016507P | 2020-04-28 | 2020-04-28 | |
| US63/016,507 | 2020-04-28 | ||
| US202063077144P | 2020-09-11 | 2020-09-11 | |
| US63/077,144 | 2020-09-11 | ||
| PCT/US2021/028658 WO2021221995A1 (en) | 2020-04-28 | 2021-04-22 | Modified nucleic acids encoding aspartoacylase (aspa) and vector for gene therapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023524024A JP2023524024A (ja) | 2023-06-08 |
| JPWO2021221995A5 true JPWO2021221995A5 (enExample) | 2024-05-01 |
| JP7821742B2 JP7821742B2 (ja) | 2026-02-27 |
Family
ID=78373856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022566010A Active JP7821742B2 (ja) | 2020-04-28 | 2021-04-22 | アスパルトアシラーゼ（ａｓｐａ）をコードする修飾核酸及び遺伝子治療のためのベクター |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230165977A1 (enExample) |
| EP (1) | EP4142759A4 (enExample) |
| JP (1) | JP7821742B2 (enExample) |
| KR (1) | KR20230003012A (enExample) |
| CN (1) | CN115461066B (enExample) |
| AU (1) | AU2021263534A1 (enExample) |
| BR (1) | BR112022021964A2 (enExample) |
| CA (1) | CA3174070A1 (enExample) |
| IL (1) | IL297605A (enExample) |
| TW (1) | TW202206599A (enExample) |
| WO (1) | WO2021221995A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3234809A1 (en) | 2021-10-20 | 2023-04-27 | Steven Goldman | Isolated glial progenitor cells for use in the competition treatment of age-related white matter loss |
| EP4426331A1 (en) | 2021-11-02 | 2024-09-11 | University of Rochester | Tcf7l2 mediated remyelination in the brain |
| WO2023221942A1 (en) | 2022-05-16 | 2023-11-23 | Shanghai Vitalgen Biopharma Co., Ltd. | Recombinant aav vectors for treating glutaric aciduria type i |
| EP4658294A2 (en) | 2023-02-02 | 2025-12-10 | University of Rochester | Competitive replacement of glial cells |
| WO2025090427A1 (en) | 2023-10-23 | 2025-05-01 | University Of Rochester | Glial-targeted relief of hyperexcitability in neurodegenerative diseases |
| WO2025129157A1 (en) * | 2023-12-15 | 2025-06-19 | The Trustees Of The University Of Pennsylvania | Gene therapy for treatment of canavan disease |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002059381A2 (en) | 2001-01-06 | 2002-08-01 | The General Hospital Corporation | Gene for identifying individuals with familial dysautonomia |
| DK2826860T3 (en) | 2010-04-23 | 2018-12-03 | Univ Massachusetts | CNS targeting AAV vectors and methods for their use |
| EP2900686B1 (en) | 2012-09-28 | 2020-06-10 | The University of North Carolina At Chapel Hill | Aav vectors targeted to oligodendrocytes |
| WO2017070525A1 (en) * | 2015-10-22 | 2017-04-27 | University Of Massachusetts | Methods and compositions for treating metabolic imbalance in neurodegenerative disease |
| WO2017181105A1 (en) | 2016-04-15 | 2017-10-19 | University Of Massachusetts | Methods and compositions for treating metabolic imbalance |
| US11078247B2 (en) * | 2016-05-04 | 2021-08-03 | Curevac Ag | RNA encoding a therapeutic protein |
| US10610606B2 (en) * | 2018-02-01 | 2020-04-07 | Homology Medicines, Inc. | Adeno-associated virus compositions for PAH gene transfer and methods of use thereof |
-
2021
- 2021-04-22 IL IL297605A patent/IL297605A/en unknown
- 2021-04-22 CA CA3174070A patent/CA3174070A1/en active Pending
- 2021-04-22 JP JP2022566010A patent/JP7821742B2/ja active Active
- 2021-04-22 KR KR1020227041079A patent/KR20230003012A/ko active Pending
- 2021-04-22 BR BR112022021964A patent/BR112022021964A2/pt unknown
- 2021-04-22 WO PCT/US2021/028658 patent/WO2021221995A1/en not_active Ceased
- 2021-04-22 CN CN202180031917.6A patent/CN115461066B/zh active Active
- 2021-04-22 US US17/997,312 patent/US20230165977A1/en active Pending
- 2021-04-22 AU AU2021263534A patent/AU2021263534A1/en active Pending
- 2021-04-22 EP EP21795587.1A patent/EP4142759A4/en active Pending
- 2021-04-28 TW TW110115439A patent/TW202206599A/zh unknown
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