JPWO2021216776A5 - - Google Patents

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Publication number
JPWO2021216776A5
JPWO2021216776A5 JP2022563870A JP2022563870A JPWO2021216776A5 JP WO2021216776 A5 JPWO2021216776 A5 JP WO2021216776A5 JP 2022563870 A JP2022563870 A JP 2022563870A JP 2022563870 A JP2022563870 A JP 2022563870A JP WO2021216776 A5 JPWO2021216776 A5 JP WO2021216776A5
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JP
Japan
Prior art keywords
sequence
nucleic acid
optionally
self
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022563870A
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English (en)
Japanese (ja)
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JP2023523414A (ja
JP2023523414A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/028486 external-priority patent/WO2021216776A2/en
Publication of JP2023523414A publication Critical patent/JP2023523414A/ja
Publication of JPWO2021216776A5 publication Critical patent/JPWO2021216776A5/ja
Publication of JP2023523414A5 publication Critical patent/JP2023523414A5/ja
Pending legal-status Critical Current

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JP2022563870A 2020-04-21 2021-04-21 キャッピング化合物、組成物、及びその使用方法 Pending JP2023523414A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063013456P 2020-04-21 2020-04-21
US63/013,456 2020-04-21
US202063020473P 2020-05-05 2020-05-05
US63/020,473 2020-05-05
PCT/US2021/028486 WO2021216776A2 (en) 2020-04-21 2021-04-21 Capping compounds, compositions and methods of use thereof

Publications (3)

Publication Number Publication Date
JP2023523414A JP2023523414A (ja) 2023-06-05
JPWO2021216776A5 true JPWO2021216776A5 (https=) 2024-05-01
JP2023523414A5 JP2023523414A5 (https=) 2024-05-01

Family

ID=78269927

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022563870A Pending JP2023523414A (ja) 2020-04-21 2021-04-21 キャッピング化合物、組成物、及びその使用方法

Country Status (9)

Country Link
US (1) US20230303614A1 (https=)
EP (1) EP4138854A4 (https=)
JP (1) JP2023523414A (https=)
KR (1) KR20230015914A (https=)
CN (1) CN115768437A (https=)
AU (1) AU2021260932A1 (https=)
CA (1) CA3173803A1 (https=)
IL (1) IL296855A (https=)
WO (1) WO2021216776A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102366490B1 (ko) * 2020-10-20 2022-02-23 에스티팜 주식회사 5'-캡핑된 rna 합성용 올리고뉴클레오티드
CN118978560A (zh) * 2021-08-27 2024-11-19 上海兆维科技发展有限公司 一种加帽类似物及其应用
CA3236959A1 (en) * 2021-11-08 2023-05-11 Sue-Jean HONG Self-amplifying rna compositions and methods of use thereof
US20250108066A1 (en) * 2022-01-27 2025-04-03 Trilink Biotechnologies, Llc Trinucleotide cap analogs and methods of use thereof
CN115260264B (zh) * 2022-02-28 2023-06-09 广州市恒诺康医药科技有限公司 用于rna加帽的化合物及其应用
JP7642260B2 (ja) 2022-02-28 2025-03-10 ▲広▼州市恒▲諾▼康医▲薬▼科技有限公司 Rnaキャッピング用化合物及びその使用
US12084703B2 (en) 2022-05-12 2024-09-10 SunVax mRNA Therapeutics Inc. Synthetic self-amplifying mRNA molecules with secretion antigen and immunomodulator
IL319652A (en) * 2022-10-04 2025-05-01 BioNTech SE RNA structures and their uses
WO2025037891A1 (ko) * 2023-08-14 2025-02-20 에스티팜 주식회사 5'-캡핑된 rna 합성용 올리고뉴클레오티드
CN120082547B (zh) * 2025-05-06 2025-10-03 北京悦康科创医药科技股份有限公司 用于自复制mRNA的加帽类似物及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0813274B2 (ja) * 1990-08-13 1996-02-14 アイシス・ファーマシューティカルス・インコーポレーテッド 遺伝子発現を検出及び変調する糖修飾されたオリゴヌクレオチド
ES2964690T3 (es) 2015-09-21 2024-04-09 Trilink Biotechnologies Llc Método para sintetizar ARN con caperuza 5'
US10967057B2 (en) * 2016-06-02 2021-04-06 Glaxosmithkline Biologicals S.A. Zika viral antigen constructs
US10487105B2 (en) * 2016-10-19 2019-11-26 Arcturus Therapeutics, Inc. Trinucleotide MRNA cap analogs
PE20191345A1 (es) * 2016-11-23 2019-09-30 Gritstone Oncology Inc Administracion viral de neoantigenos
MX2019013259A (es) * 2017-05-08 2020-01-13 Gritstone Oncology Inc Vectores de neoantigeno de alfavirus.
ES2983060T3 (es) * 2017-08-18 2024-10-21 Modernatx Inc Variantes de ARN polimerasa

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