JPWO2021203046A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2021203046A5
JPWO2021203046A5 JP2022560250A JP2022560250A JPWO2021203046A5 JP WO2021203046 A5 JPWO2021203046 A5 JP WO2021203046A5 JP 2022560250 A JP2022560250 A JP 2022560250A JP 2022560250 A JP2022560250 A JP 2022560250A JP WO2021203046 A5 JPWO2021203046 A5 JP WO2021203046A5
Authority
JP
Japan
Prior art keywords
cells
cell
present
mitochondria
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022560250A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023521037A (ja
JP2023521037A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/025643 external-priority patent/WO2021203046A1/en
Publication of JP2023521037A publication Critical patent/JP2023521037A/ja
Publication of JPWO2021203046A5 publication Critical patent/JPWO2021203046A5/ja
Publication of JP2023521037A5 publication Critical patent/JP2023521037A5/ja
Pending legal-status Critical Current

Links

JP2022560250A 2020-04-03 2021-04-02 養子細胞移植の強化 Pending JP2023521037A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063005167P 2020-04-03 2020-04-03
US63/005,167 2020-04-03
PCT/US2021/025643 WO2021203046A1 (en) 2020-04-03 2021-04-02 Enhancement of adoptive cell transfer

Publications (3)

Publication Number Publication Date
JP2023521037A JP2023521037A (ja) 2023-05-23
JPWO2021203046A5 true JPWO2021203046A5 (https=) 2024-04-15
JP2023521037A5 JP2023521037A5 (https=) 2024-04-15

Family

ID=75919371

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022560250A Pending JP2023521037A (ja) 2020-04-03 2021-04-02 養子細胞移植の強化

Country Status (7)

Country Link
US (2) US20210309967A1 (https=)
EP (1) EP4127141A1 (https=)
JP (1) JP2023521037A (https=)
CN (1) CN116096861A (https=)
AU (1) AU2021246112A1 (https=)
CA (1) CA3173391A1 (https=)
WO (1) WO2021203046A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12419913B2 (en) 2019-02-08 2025-09-23 Dna Twopointo, Inc. Modification of CAR-T cells
CN118541160A (zh) * 2021-10-06 2024-08-23 赛立维公司 通过促进优越的适应性免疫细胞群体增强过继细胞转移
CA3257638A1 (en) 2022-06-10 2023-12-14 Cellvie Ag COMPOSITION AND CRYOCONSERVATION PROCESS OF MITOCHONDRIA
US20260041767A1 (en) * 2022-08-02 2026-02-12 National University Corporation Hokkaido University Methods of improving cellular therapy with organelle complexes
WO2024076572A1 (en) * 2022-10-06 2024-04-11 Mitrix Bio Inc. Formulations and methods for cellular therapies involving chimeric antigen receptors
WO2024097901A1 (en) * 2022-11-02 2024-05-10 Fate Therapeutics, Inc. Off-the-shelf therapeutic cells with multiplex genomic engineering for targeting cd79b

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2694549B1 (en) 2011-04-08 2018-08-15 The United States of America, as represented by The Secretary, Department of Health and Human Services Anti-epidermal growth factor receptor variant iii chimeric antigen receptors and use of same for the treatment of cancer
US11491480B2 (en) 2014-06-13 2022-11-08 Children's Medical Center Corporation Products and methods to isolate mitochondria
WO2016008937A1 (en) * 2014-07-16 2016-01-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the intercellular transfer of isolated mitochondria in recipient cells
AU2015343013B2 (en) * 2014-11-05 2020-07-16 Board Of Regents, The University Of Texas System Gene modified immune effector cells and engineered cells for expansion of immune effector cells
SI4272834T1 (sl) * 2016-01-15 2026-03-31 Beth Israel Deaconess Medical Center, Inc. Terapevtska uporaba mitohondrijev in kombiniranih mitohondrijskih sredstev
WO2018088875A2 (ko) * 2016-11-14 2018-05-17 주식회사 파이안에스테틱스 외래 미토콘드리아를 포함하는 자연살해세포 및 이를 포함하는 약학적 조성물
JP7524157B2 (ja) * 2018-07-22 2024-07-29 ミノヴィア セラピューティクス リミテッド 脳疾患のミトコンドリア増強療法
KR20210042125A (ko) * 2018-08-07 2021-04-16 퍼듀 리서치 파운데이션 Car t 세포의 회생
EP3837359A4 (en) * 2018-08-14 2022-05-11 Imel Biotherapeutics, Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF MITOCHONDRIAL DISEASES OR DISORDERS AND HETEROPLASMIA
CA3172402A1 (en) * 2020-03-31 2021-10-07 Minovia Therapeutics Ltd. Mitochondria-enriched genetically engineered cells and uses thereof

Similar Documents

Publication Publication Date Title
JP7450892B2 (ja) Nk細胞のための人工hla陽性フィーダー細胞株及びその使用
US20200038443A1 (en) Multi-function and multi-targeting car system and methods for use thereof
JP2025000906A (ja) 固形腫瘍を標的とする二重特異性car t細胞
CN118420783A (zh) 嵌合蛋白、表达嵌合蛋白的免疫效应细胞及其应用
WO2019052562A1 (zh) Il-4r的融合蛋白及其应用
EP3789486A1 (en) Immune effector cell and use thereof
WO2022037562A1 (en) Engineered immunoresponsive cells and uses thereof
WO2021057906A1 (zh) 表达il-15的免疫效应细胞
WO2020143631A1 (zh) 细胞免疫治疗的组合
WO2021052496A1 (zh) 细胞因子调控表达的免疫效应细胞
JP2021513860A (ja) ユニバーサル抗原提示細胞およびその使用
EP4138864A1 (en) Polyspecific binding molecules and their use in cell therapy
WO2022057941A1 (zh) 表达il-7r结合蛋白的免疫效应细胞
JP2025520124A (ja) キメラアダプターポリペプチドを含む組成物及び方法
JP2024515815A (ja) 組換え抗原提示細胞
JPWO2021203046A5 (https=)
WO2022092277A1 (ja) Cxcl12受容体発現キメラ抗原受容体(car)-t細胞
WO2022095903A1 (zh) 靶向pd-1h(vista)的抗肿瘤免疫治疗方法
EP3991746A1 (en) Transfection method
WO2023284875A1 (zh) 嵌合抗原受体
CN118477171A (zh) 脂质纳米颗粒 (lnp) 及其在细胞治疗中的用途
US20240075085A1 (en) Cancer therapy involving car-engineered t-cells and parvovirus h-1
WO2025103439A1 (zh) 一种嵌合抗原受体及其应用
WO2025130895A1 (zh) 一种免疫细胞的制备方法及其用途
WO2024124244A1 (en) Cd38 as integration site for enhanced function of gene-modified immune cells