JPWO2021167919A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2021167919A5 JPWO2021167919A5 JP2022549613A JP2022549613A JPWO2021167919A5 JP WO2021167919 A5 JPWO2021167919 A5 JP WO2021167919A5 JP 2022549613 A JP2022549613 A JP 2022549613A JP 2022549613 A JP2022549613 A JP 2022549613A JP WO2021167919 A5 JPWO2021167919 A5 JP WO2021167919A5
- Authority
- JP
- Japan
- Prior art keywords
- aav
- capsid protein
- derivative
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062977838P | 2020-02-18 | 2020-02-18 | |
| US62/977,838 | 2020-02-18 | ||
| US202063023003P | 2020-05-11 | 2020-05-11 | |
| US63/023,003 | 2020-05-11 | ||
| PCT/US2021/018280 WO2021167919A1 (en) | 2020-02-18 | 2021-02-17 | Aav capsid-promoter interactions and cell selective gene expression |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023515795A JP2023515795A (ja) | 2023-04-14 |
| JPWO2021167919A5 true JPWO2021167919A5 (https=) | 2024-02-27 |
| JP2023515795A5 JP2023515795A5 (https=) | 2024-02-27 |
Family
ID=77391215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022549613A Pending JP2023515795A (ja) | 2020-02-18 | 2021-02-17 | Ａａｖカプシド－プロモーター相互作用および細胞選択的遺伝子発現 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230013145A1 (https=) |
| EP (1) | EP4107169A4 (https=) |
| JP (1) | JP2023515795A (https=) |
| CN (1) | CN115210248A (https=) |
| AU (1) | AU2021224551A1 (https=) |
| CA (1) | CA3164321A1 (https=) |
| WO (1) | WO2021167919A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20250206783A1 (en) * | 2022-03-21 | 2025-06-26 | Capsigen Inc. | Transcription-dependent directed evolution of aav capsids having enhanced tropism |
| WO2023201306A1 (en) | 2022-04-14 | 2023-10-19 | Invisishield Technologies Ltd. | Compositions for preventing or treating influenza infections |
| WO2025230969A1 (en) * | 2024-05-02 | 2025-11-06 | 4D Molecular Therapeutics Inc. | Aav variants with improved cns tropism and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003221733A1 (en) * | 2002-04-17 | 2003-11-03 | University Of Florida Research Foundation, Inc. | Improved raav vectors |
| US20060093589A1 (en) * | 2004-02-19 | 2006-05-04 | Warrington Kenneth H | Vp2-modified raav vector compositions and uses therefor |
| EP1618201A1 (en) * | 2003-05-01 | 2006-01-25 | University of Florida Research Foundation, Inc. | Vp2 - modified raav vectors and uses thereof |
| WO2010071454A1 (en) * | 2008-12-17 | 2010-06-24 | Auckland Uniservices Limited | Adeno-associated viral vectors and uses thereof |
| IL248102B (en) * | 2014-05-02 | 2022-07-01 | Genzyme Corp | aav vectors for gene therapy of the central nervous system and retina |
| WO2016081811A1 (en) * | 2014-11-21 | 2016-05-26 | The University Of North Carolina At Chapel Hill | Aav vectors targeted to the central nervous system |
-
2021
- 2021-02-17 US US17/904,433 patent/US20230013145A1/en active Pending
- 2021-02-17 CN CN202180017627.6A patent/CN115210248A/zh active Pending
- 2021-02-17 CA CA3164321A patent/CA3164321A1/en active Pending
- 2021-02-17 JP JP2022549613A patent/JP2023515795A/ja active Pending
- 2021-02-17 WO PCT/US2021/018280 patent/WO2021167919A1/en not_active Ceased
- 2021-02-17 AU AU2021224551A patent/AU2021224551A1/en not_active Abandoned
- 2021-02-17 EP EP21756717.1A patent/EP4107169A4/en not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20250127922A1 (en) | Capsid | |
| US20240197918A1 (en) | Tissue-targeted modified aav capsids and methods of use thereof | |
| Grieger et al. | Adeno-associated virus vectorology, manufacturing, and clinical applications | |
| JP2019116492A5 (https=) | ||
| Chiorini et al. | Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles | |
| US8420372B2 (en) | Porcine adeno-associated viruses | |
| KR102405250B1 (ko) | 컬럼-기반 완전히 확장 가능한 rAAV 제조 공정 | |
| JP2021523718A5 (https=) | ||
| JPWO2020106916A5 (https=) | ||
| CN121925426A (zh) | 肝脏去靶向衣壳 | |
| CN120787264A (zh) | 肝脏去靶向衣壳 | |
| CN120548368A (zh) | 用于正确包装重复元件的腺相关病毒载体 | |
| Wu et al. | Popularizing recombinant baculovirus-derived onebac system for laboratory production of all recombinant adeno-associated virus vector serotypes | |
| JPWO2021050614A5 (https=) | ||
| JPWO2021167919A5 (https=) | ||
| JPWO2021011029A5 (https=) | ||
| CN120882875A (zh) | 肌肉靶向衣壳 | |
| JP2025515356A5 (https=) | ||
| JP2025524619A (ja) | 組換えａａｖ粒子を産生するための方法 | |
| JPWO2021076911A5 (https=) | ||
| RU2820088C1 (ru) | Выделенный модифицированный белок VPI капсида аденоассоциированного вируса 5 серотипа (AAV5), капсид и вектор на его основе | |
| RU2022111695A (ru) | Выделенная нуклеиновая кислота, которая кодирует слитый белок на основе FVIII-BDD и гетерологичного сигнального пептида, и ее применение | |
| JPWO2020047472A5 (https=) | ||
| JP2025514313A5 (https=) | ||
| CN119331061A (zh) | 靶向中枢神经系统的aav衣壳蛋白变体及其用途 |