JPWO2021157681A1 - - Google Patents

Info

Publication number
JPWO2021157681A1
JPWO2021157681A1 JP2021575874A JP2021575874A JPWO2021157681A1 JP WO2021157681 A1 JPWO2021157681 A1 JP WO2021157681A1 JP 2021575874 A JP2021575874 A JP 2021575874A JP 2021575874 A JP2021575874 A JP 2021575874A JP WO2021157681 A1 JPWO2021157681 A1 JP WO2021157681A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021575874A
Other languages
Japanese (ja)
Other versions
JPWO2021157681A5 (https=
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2021157681A1 publication Critical patent/JPWO2021157681A1/ja
Publication of JPWO2021157681A5 publication Critical patent/JPWO2021157681A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/321—2'-O-R Modification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/322—2'-R Modification

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2021575874A 2020-02-06 2021-02-05 Pending JPWO2021157681A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062970842P 2020-02-06 2020-02-06
PCT/JP2021/004215 WO2021157681A1 (ja) 2020-02-06 2021-02-05 網膜下高反射病巣または網膜下高反射病巣を伴う網膜疾患の治療剤

Publications (2)

Publication Number Publication Date
JPWO2021157681A1 true JPWO2021157681A1 (https=) 2021-08-12
JPWO2021157681A5 JPWO2021157681A5 (https=) 2022-11-11

Family

ID=77199348

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021575874A Pending JPWO2021157681A1 (https=) 2020-02-06 2021-02-05

Country Status (7)

Country Link
US (1) US20230065106A1 (https=)
EP (1) EP4122471A4 (https=)
JP (1) JPWO2021157681A1 (https=)
KR (1) KR20220137699A (https=)
CN (1) CN115175684A (https=)
TW (1) TWI868308B (https=)
WO (1) WO2021157681A1 (https=)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009509962A (ja) * 2005-09-22 2009-03-12 インターミューン インコーポレイテッド ピルフェニドンおよび薬学的に受容可能な賦形剤のカプセル処方物
WO2020004607A1 (ja) * 2018-06-29 2020-01-02 株式会社リボミック アプタマー製剤
JP2020500938A (ja) * 2016-12-08 2020-01-16 ボロディック ゲイリー イーＢＯＲＯＤＩＣ，Ｇａｒｙ Ｅ． 黄斑変性症の新しい治療法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660985A (en) 1990-06-11 1997-08-26 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands containing modified nucleotides
US20050043220A1 (en) * 2002-11-08 2005-02-24 Guyer David R. Methods and compositions for treating macular degeneration
EP2535410A4 (en) * 2010-02-12 2014-08-13 Ribomic Inc APTAMER FOR FGF2 AND USE THEREOF
WO2013186857A1 (ja) * 2012-06-12 2013-12-19 株式会社リボミック Ｆｇｆ２に対するアプタマー及びその使用
CA2943772C (en) * 2014-03-24 2022-07-19 Ribomic Inc. Aptamer for fgf2 and use thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009509962A (ja) * 2005-09-22 2009-03-12 インターミューン インコーポレイテッド ピルフェニドンおよび薬学的に受容可能な賦形剤のカプセル処方物
JP2020500938A (ja) * 2016-12-08 2020-01-16 ボロディック ゲイリー イーＢＯＲＯＤＩＣ，Ｇａｒｙ Ｅ． 黄斑変性症の新しい治療法
WO2020004607A1 (ja) * 2018-06-29 2020-01-02 株式会社リボミック アプタマー製剤

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MATSUDA Y.ET AL.: "Anti-angiogenic and anti-scarring dual action of an anti-fibroblast growth factor 2 aptamer in anima", MOL.THER.NUCLEIC ACIDS, vol. 17, JPN6021009266, 2019, pages 819 - 828, ISSN: 0005519453 *
木村和博: "難治性網膜硝子体疾患における線維性増殖組織形成に対するSex hormoneの作用", 山口医学, vol. 64, JPN6021009267, 2015, pages 11 - 16, ISSN: 0005519454 *

Also Published As

Publication number Publication date
TWI868308B (zh) 2025-01-01
EP4122471A4 (en) 2025-02-19
EP4122471A1 (en) 2023-01-25
TW202142240A (zh) 2021-11-16
US20230065106A1 (en) 2023-03-02
KR20220137699A (ko) 2022-10-12
WO2021157681A1 (ja) 2021-08-12
CN115175684A (zh) 2022-10-11

Similar Documents

Publication Publication Date Title
BR112023005462A2 (https=)
BR112023012656A2 (https=)
BR112021014123A2 (https=)
BR112023009656A2 (https=)
BR112022009896A2 (https=)
BR112021017747A2 (https=)
BR112022024743A2 (https=)
BR112022026905A2 (https=)
BR112023011738A2 (https=)
BR112023004146A2 (https=)
BR112023006729A2 (https=)
BR102021018859A2 (https=)
BR102021015500A2 (https=)
BR112023016292A2 (https=)
BR112023011539A2 (https=)
BR112023011610A2 (https=)
BR112023008976A2 (https=)
BR102021020147A2 (https=)
BR102021018926A2 (https=)
BR102021018167A2 (https=)
BR102021017576A2 (https=)
BR102021016837A2 (https=)
BR102021016551A2 (https=)
BR102021016375A2 (https=)
BR102021016200A2 (https=)

Legal Events

Date Code Title Description
A529 Written submission of copy of amendment under article 34 pct

Free format text: JAPANESE INTERMEDIATE CODE: A5211

Effective date: 20220606

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20231215

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20250204

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20250701