JPWO2021148501A5 - - Google Patents
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- JPWO2021148501A5 JPWO2021148501A5 JP2022544188A JP2022544188A JPWO2021148501A5 JP WO2021148501 A5 JPWO2021148501 A5 JP WO2021148501A5 JP 2022544188 A JP2022544188 A JP 2022544188A JP 2022544188 A JP2022544188 A JP 2022544188A JP WO2021148501 A5 JPWO2021148501 A5 JP WO2021148501A5
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- JP
- Japan
- Prior art keywords
- compound according
- formula
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- cit
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062964180P | 2020-01-22 | 2020-01-22 | |
| US62/964,180 | 2020-01-22 | ||
| US202063085414P | 2020-09-30 | 2020-09-30 | |
| US63/085,414 | 2020-09-30 | ||
| PCT/EP2021/051263 WO2021148501A1 (en) | 2020-01-22 | 2021-01-21 | Compounds and conjugates thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023512501A JP2023512501A (ja) | 2023-03-27 |
| JPWO2021148501A5 true JPWO2021148501A5 (https=) | 2024-01-19 |
| JP2023512501A5 JP2023512501A5 (https=) | 2024-01-19 |
Family
ID=74418415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022544188A Withdrawn JP2023512501A (ja) | 2020-01-22 | 2021-01-21 | 化合物及びその複合体 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20230111996A1 (https=) |
| EP (1) | EP4093438A1 (https=) |
| JP (1) | JP2023512501A (https=) |
| KR (1) | KR20220130191A (https=) |
| CN (1) | CN115052633A (https=) |
| AU (1) | AU2021211892A1 (https=) |
| BR (1) | BR112022013966A2 (https=) |
| CA (1) | CA3167373A1 (https=) |
| CO (1) | CO2022011178A2 (https=) |
| CR (1) | CR20220393A (https=) |
| EC (1) | ECSP22064855A (https=) |
| IL (1) | IL294645A (https=) |
| MX (1) | MX2022008997A (https=) |
| TW (1) | TW202140076A (https=) |
| WO (1) | WO2021148501A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118414339A (zh) | 2021-12-16 | 2024-07-30 | 迈威(上海)生物科技股份有限公司 | 一种喜树碱类化合物及其偶联物 |
| CN115160403B (zh) * | 2022-07-05 | 2025-06-27 | 博石丰生命科技(南通)有限公司 | 特异性拓扑异构酶抑制剂和可用于抗体药物偶联物及其制备方法 |
| JP2025524728A (ja) | 2022-07-15 | 2025-07-30 | フィアン セラピューティクス エルティーディー | 抗体－薬物複合体 |
| EP4309676A1 (en) * | 2022-07-22 | 2024-01-24 | Emergence Therapeutics AG | Novel anti-nectin-4 antibody camptothecin derivative conjugates |
| EP4583921A1 (en) * | 2022-09-07 | 2025-07-16 | Xadcera Biopharmaceutical (Suzhou) Co., Ltd. | Anti-trop2/egfr antibodies and uses thereof |
| CN119630672B (zh) * | 2023-02-23 | 2026-01-30 | 一线医药（杭州）有限公司 | 喜树碱衍生物及其偶联物以及其制备方法和医药用途 |
| TW202508638A (zh) * | 2023-05-12 | 2025-03-01 | 大陸商百奧賽圖(北京)醫藥科技股份有限公司 | 連結子化合物及配體－藥物接合物、其製備方法及用途 |
| EP4721767A1 (en) | 2023-06-05 | 2026-04-08 | Jiangsu Mabwell Health Pharmaceutical R&D Co., Ltd. | Anti-b7-h3 antibody or fragment thereof, and antibody drug conjugate targeting b7-h3 |
| WO2025103192A1 (zh) * | 2023-11-16 | 2025-05-22 | 上海齐鲁制药研究中心有限公司 | 一种氘代喜树碱化合物及其制备和应用 |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4939255A (en) * | 1987-06-24 | 1990-07-03 | Daiichi Pharmaceutical Co., Ltd. | Hexa-cyclic camptothecin derivatives |
| JP3008226B2 (ja) * | 1991-01-16 | 2000-02-14 | 第一製薬株式会社 | 六環性化合物 |
| KR101270829B1 (ko) | 2004-09-23 | 2013-06-07 | 제넨테크, 인크. | 시스테인 유전자조작 항체 및 접합체 |
| HRP20110498T1 (hr) | 2005-10-07 | 2011-08-31 | Exelixis | Azetidini kao inhibitori mek za liječenje proliferativnih bolesti |
| SI1813614T1 (sl) | 2006-01-25 | 2012-01-31 | Sanofi 174 | Citotoksična sredstva, ki obsegajo nove tomajmicinske derivate |
| EP2144628B1 (en) | 2007-05-08 | 2012-10-17 | Genentech, Inc. | Cysteine engineered anti-muc16 antibodies and antibody drug conjugates |
| MX2010003718A (es) | 2007-10-19 | 2010-04-21 | Genentech Inc | Anticuerpos anti-tenb2 producidos por ingenieria de cisteina y conjugados de farmaco y anticuerpo. |
| GB201506393D0 (en) * | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
| EP3362100B1 (en) * | 2015-10-16 | 2022-06-22 | Genentech, Inc. | Hindered disulfide drug conjugates |
| GB201607478D0 (en) | 2016-04-29 | 2016-06-15 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| WO2018089393A1 (en) | 2016-11-10 | 2018-05-17 | Medimmune, Llc | Binding molecules specific for asct2 and uses thereof |
| HUE060364T2 (hu) * | 2019-03-29 | 2023-02-28 | Medimmune Ltd | Vegyületek és konjugátumaik |
| CR20230146A (es) * | 2020-09-11 | 2023-06-07 | Medimmune Ltd | Moléculas de unión a b7-h4 terapéuticas |
-
2021
- 2021-01-20 TW TW110102103A patent/TW202140076A/zh unknown
- 2021-01-21 KR KR1020227028554A patent/KR20220130191A/ko active Pending
- 2021-01-21 CR CR20220393A patent/CR20220393A/es unknown
- 2021-01-21 MX MX2022008997A patent/MX2022008997A/es unknown
- 2021-01-21 WO PCT/EP2021/051263 patent/WO2021148501A1/en not_active Ceased
- 2021-01-21 BR BR112022013966A patent/BR112022013966A2/pt not_active IP Right Cessation
- 2021-01-21 EP EP21702401.7A patent/EP4093438A1/en not_active Withdrawn
- 2021-01-21 IL IL294645A patent/IL294645A/en unknown
- 2021-01-21 JP JP2022544188A patent/JP2023512501A/ja not_active Withdrawn
- 2021-01-21 CN CN202180010204.1A patent/CN115052633A/zh active Pending
- 2021-01-21 US US17/759,078 patent/US20230111996A1/en not_active Abandoned
- 2021-01-21 AU AU2021211892A patent/AU2021211892A1/en not_active Abandoned
- 2021-01-21 CA CA3167373A patent/CA3167373A1/en active Pending
-
2022
- 2022-08-08 CO CONC2022/0011178A patent/CO2022011178A2/es unknown
- 2022-08-18 EC ECSENADI202264855A patent/ECSP22064855A/es unknown
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