JPWO2021148006A5 - - Google Patents
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- JPWO2021148006A5 JPWO2021148006A5 JP2022544309A JP2022544309A JPWO2021148006A5 JP WO2021148006 A5 JPWO2021148006 A5 JP WO2021148006A5 JP 2022544309 A JP2022544309 A JP 2022544309A JP 2022544309 A JP2022544309 A JP 2022544309A JP WO2021148006 A5 JPWO2021148006 A5 JP WO2021148006A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- substitutions
- substitution
- heterodimeric protein
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2020/073960 | 2020-01-23 | ||
| CN2020073960 | 2020-01-23 | ||
| PCT/CN2021/073347 WO2021148006A1 (en) | 2020-01-23 | 2021-01-22 | Heterodimeric proteins with fc mutations |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023511376A JP2023511376A (ja) | 2023-03-17 |
| JPWO2021148006A5 true JPWO2021148006A5 (enrdf_load_html_response) | 2025-04-21 |
| JP7710450B2 JP7710450B2 (ja) | 2025-07-18 |
Family
ID=76992067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022544309A Active JP7710450B2 (ja) | 2020-01-23 | 2021-01-22 | Ｆｃ変異を有するヘテロダイマータンパク質 |
Country Status (12)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022170619A1 (en) * | 2021-02-11 | 2022-08-18 | Adagene Pte. Ltd. | Anti-cd3 antibodies and methods of use thereof |
| EP4496816A1 (en) * | 2022-03-23 | 2025-01-29 | CytomX Therapeutics, Inc. | Activatable antigen-binding protein constructs and uses of the same |
| WO2023193239A1 (en) | 2022-04-08 | 2023-10-12 | Peter Peizhi Luo | Anti-cd28 antibodies and methods of use thereof |
| WO2025014914A1 (en) * | 2023-07-10 | 2025-01-16 | Regeneron Pharmaceuticals, Inc. | Bispecific pd-l1x4-1bb antibodies and methods of use thereof |
| TW202528360A (zh) * | 2023-11-20 | 2025-07-16 | 大陸商江蘇恆瑞醫藥股份有限公司 | 藉由重組反應製備異源多聚體的方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006034488A2 (en) * | 2004-09-23 | 2006-03-30 | Genentech, Inc. | Cysteine engineered antibodies and conjugates |
| US8054928B2 (en) * | 2005-11-14 | 2011-11-08 | Ati Technologies, Inc. | Programmable preamble system and method |
| US20100189651A1 (en) * | 2009-01-12 | 2010-07-29 | Cytomx Therapeutics, Llc | Modified antibody compositions, methods of making and using thereof |
| US9493578B2 (en) * | 2009-09-02 | 2016-11-15 | Xencor, Inc. | Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens |
| CA3051311A1 (en) * | 2010-05-27 | 2011-12-01 | Genmab A/S | Monoclonal antibodies against her2 |
| JP6475017B2 (ja) * | 2011-10-27 | 2019-02-27 | ゲンマブ エー／エス | ヘテロ二量体タンパク質の作出 |
| DE112013000868B8 (de) * | 2012-02-06 | 2021-03-11 | Toyota Jidosha Kabushiki Kaisha | Sulfidfestkörperelektrolytmaterial, Batterie und Herstellungsverfahren für das Sulfidfestkörperelektrolytmaterial |
| UY35148A (es) * | 2012-11-21 | 2014-05-30 | Amgen Inc | Immunoglobulinas heterodiméricas |
| KR102211176B1 (ko) * | 2013-03-15 | 2021-02-01 | 젠코어 인코포레이티드 | 이형이량체 단백질 |
| EA036577B1 (ru) * | 2013-11-04 | 2020-11-25 | Икнос Сайенсиз Са | Получение переориентирующих т-клетки гетеродимерных иммуноглобулинов |
| US20160176969A1 (en) * | 2014-11-26 | 2016-06-23 | Xencor, Inc. | Heterodimeric antibodies including binding to cd8 |
| JP6721590B2 (ja) * | 2014-12-03 | 2020-07-15 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 多重特異性抗体 |
| CN107408987B (zh) * | 2015-03-20 | 2020-03-17 | 日本电气株式会社 | 可插拔光模块、光通信系统和可插拔光模块控制方法 |
| CN106883297B (zh) | 2015-12-16 | 2019-12-13 | 苏州康宁杰瑞生物科技有限公司 | 基于ch3结构域的异二聚体分子、其制备方法及用途 |
| CN117143247A (zh) | 2016-07-19 | 2023-12-01 | 伊班绰斯有限责任公司 | 双特异性蛋白质及其制备方法 |
| WO2019014912A1 (zh) * | 2017-07-21 | 2019-01-24 | 赵磊 | 一种异二聚体蛋白及其制备方法 |
| EP3728326A4 (en) | 2017-12-21 | 2021-12-15 | Amunix Pharmaceuticals, Inc. | RELEASE SEGMENTS AND LIAISON COMPOSITIONS INCLUDING THEM |
| WO2019148445A1 (en) | 2018-02-02 | 2019-08-08 | Adagene Inc. | Precision/context-dependent activatable antibodies, and methods of making and using the same |
| TWI798601B (zh) * | 2020-11-27 | 2023-04-11 | 晶睿通訊股份有限公司 | 地面起伏偵測方法及其監控攝影機 |
| JP7295438B2 (ja) * | 2020-11-30 | 2023-06-21 | 日亜化学工業株式会社 | 面状光源 |
| WO2023193239A1 (en) * | 2022-04-08 | 2023-10-12 | Peter Peizhi Luo | Anti-cd28 antibodies and methods of use thereof |
-
2021
- 2021-01-22 US US17/759,282 patent/US20230124669A1/en active Pending
- 2021-01-22 IL IL294878A patent/IL294878A/en unknown
- 2021-01-22 JP JP2022544309A patent/JP7710450B2/ja active Active
- 2021-01-22 AU AU2021210482A patent/AU2021210482A1/en active Pending
- 2021-01-22 EP EP21744991.7A patent/EP4093778A4/en active Pending
- 2021-01-22 CN CN202180021100.0A patent/CN115279796A/zh active Pending
- 2021-01-22 KR KR1020227029071A patent/KR20220145833A/ko active Pending
- 2021-01-22 BR BR112022014574A patent/BR112022014574A2/pt unknown
- 2021-01-22 MX MX2022009101A patent/MX2022009101A/es unknown
- 2021-01-22 TW TW110102586A patent/TW202140570A/zh unknown
- 2021-01-22 WO PCT/CN2021/073347 patent/WO2021148006A1/en not_active Ceased
- 2021-01-22 CA CA3165045A patent/CA3165045A1/en active Pending
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