JPWO2021143706A5 - - Google Patents
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- JPWO2021143706A5 JPWO2021143706A5 JP2022542655A JP2022542655A JPWO2021143706A5 JP WO2021143706 A5 JPWO2021143706 A5 JP WO2021143706A5 JP 2022542655 A JP2022542655 A JP 2022542655A JP 2022542655 A JP2022542655 A JP 2022542655A JP WO2021143706 A5 JPWO2021143706 A5 JP WO2021143706A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound according
- cycloalkyl
- compound
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2020/071741 | 2020-01-13 | ||
| CN2020071741 | 2020-01-13 | ||
| CNPCT/CN2020/107757 | 2020-08-07 | ||
| CN2020107757 | 2020-08-07 | ||
| PCT/CN2021/071381 WO2021143706A1 (en) | 2020-01-13 | 2021-01-13 | Substituted triazinones as thyroid hormone receptor agonists |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2023510835A JP2023510835A (ja) | 2023-03-15 |
| JP2023510835A5 JP2023510835A5 (https=) | 2024-01-25 |
| JPWO2021143706A5 true JPWO2021143706A5 (https=) | 2024-01-25 |
| JP7728265B2 JP7728265B2 (ja) | 2025-08-22 |
Family
ID=74418122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022542655A Active JP7728265B2 (ja) | 2020-01-13 | 2021-01-13 | 甲状腺ホルモン受容体アゴニストとしての置換トリアジノン |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11780825B2 (https=) |
| EP (1) | EP4090652A1 (https=) |
| JP (1) | JP7728265B2 (https=) |
| KR (1) | KR20220128383A (https=) |
| CN (1) | CN115244037B (https=) |
| AU (1) | AU2021208027B2 (https=) |
| IL (1) | IL294494A (https=) |
| MX (1) | MX2022008626A (https=) |
| WO (1) | WO2021143706A1 (https=) |
| ZA (1) | ZA202207541B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GEP20247637B (en) | 2019-05-08 | 2024-06-25 | Aligos Therapeutics Inc | Modulators of thr-b and methods of use thereof |
| EP4090652A1 (en) | 2020-01-13 | 2022-11-23 | Eccogene (Shanghai) Co., Ltd. | Substituted triazinones as thyroid hormone receptor agonists |
| JP7813730B2 (ja) | 2020-06-17 | 2026-02-13 | オートバーン セラピューティクス，インク． | 甲状腺様作用剤 |
| WO2021257851A1 (en) | 2020-06-17 | 2021-12-23 | Autobahn Therapeutics, Inc. | Thyromimetics |
| EP4240730A1 (en) | 2020-11-06 | 2023-09-13 | Aligos Therapeutics, Inc. | 2-pyridones as thyroid hormone receptor modulators |
| CN114685450A (zh) * | 2020-12-30 | 2022-07-01 | 昆药集团股份有限公司 | 2-吡啶酮类衍生物及其制备方法和在医药上的应用 |
| CN117624069A (zh) * | 2022-08-19 | 2024-03-01 | 凯思凯迪（上海）医药科技有限公司 | 一种多环类甲状腺激素β受体激动剂及其用途 |
| CN118146123A (zh) * | 2024-02-04 | 2024-06-07 | 河北鼎泰制药有限公司 | 一种盐酸安罗替尼中间体的合成方法 |
| WO2026067791A1 (en) * | 2024-09-30 | 2026-04-02 | Ascletis Pharma (China) Co., Limited | 2-phenyl-1,2,4-triazine-3,5(2h,4h)-dione derivatives as thr-beta agonist or modulators for the treatment of obesity |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| EP1088819B1 (en) * | 1999-09-30 | 2005-06-15 | Pfizer Products Inc. | 6-azauracil derivatives as thyroid receptor ligands |
| DK1262177T3 (da) | 2001-05-31 | 2006-11-20 | Pfizer Prod Inc | Medicinsk brug af thyromimetiske forbindelser til behandling af hårtab og kompositioner |
| PL1919878T3 (pl) | 2005-07-21 | 2011-03-31 | Hoffmann La Roche | Pochodne pirydazynonu jako agoniści receptora hormonu tarczycy |
| US8076334B2 (en) | 2007-09-20 | 2011-12-13 | Hoffmann-La Roche Inc. | Prodrugs of thyroid hormone analogs |
| TWI534144B (zh) | 2009-04-20 | 2016-05-21 | 田邊三菱製藥股份有限公司 | 甲狀腺荷爾蒙β受體作動藥 |
| JP5847533B2 (ja) | 2010-10-19 | 2016-01-27 | 田辺三菱製薬株式会社 | 新規甲状腺ホルモンβ受容体作動薬 |
| CN109574995B (zh) | 2018-01-23 | 2020-07-24 | 深圳市塔吉瑞生物医药有限公司 | 取代的哒嗪酮化合物 |
| CN111801324B (zh) | 2018-06-12 | 2021-10-22 | 四川海思科制药有限公司 | 甲状腺激素受体激动剂及其用途 |
| US12338206B2 (en) | 2019-02-21 | 2025-06-24 | Nanjing Ruijie Pharma Co., Ltd. | Compounds and their uses as thyroid hormone receptor agonists |
| EP4090652A1 (en) | 2020-01-13 | 2022-11-23 | Eccogene (Shanghai) Co., Ltd. | Substituted triazinones as thyroid hormone receptor agonists |
| JP7813730B2 (ja) * | 2020-06-17 | 2026-02-13 | オートバーン セラピューティクス，インク． | 甲状腺様作用剤 |
-
2021
- 2021-01-13 EP EP21702359.7A patent/EP4090652A1/en active Pending
- 2021-01-13 CN CN202180019696.0A patent/CN115244037B/zh active Active
- 2021-01-13 KR KR1020227027435A patent/KR20220128383A/ko active Pending
- 2021-01-13 AU AU2021208027A patent/AU2021208027B2/en active Active
- 2021-01-13 WO PCT/CN2021/071381 patent/WO2021143706A1/en not_active Ceased
- 2021-01-13 MX MX2022008626A patent/MX2022008626A/es unknown
- 2021-01-13 US US17/147,538 patent/US11780825B2/en active Active
- 2021-01-13 IL IL294494A patent/IL294494A/en unknown
- 2021-01-13 JP JP2022542655A patent/JP7728265B2/ja active Active
-
2022
- 2022-07-07 ZA ZA2022/07541A patent/ZA202207541B/en unknown
-
2023
- 2023-08-11 US US18/448,277 patent/US12291518B2/en active Active
-
2025
- 2025-03-03 US US19/068,129 patent/US20250320197A1/en active Pending
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