JPWO2021097174A5 - - Google Patents
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- Publication number
- JPWO2021097174A5 JPWO2021097174A5 JP2022528047A JP2022528047A JPWO2021097174A5 JP WO2021097174 A5 JPWO2021097174 A5 JP WO2021097174A5 JP 2022528047 A JP2022528047 A JP 2022528047A JP 2022528047 A JP2022528047 A JP 2022528047A JP WO2021097174 A5 JPWO2021097174 A5 JP WO2021097174A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- volume
- airway inflammation
- nanoemulsion
- surfactant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 8
- 208000037883 airway inflammation Diseases 0.000 claims 4
- 239000004094 surface-active agent Substances 0.000 claims 4
- 239000007908 nanoemulsion Substances 0.000 claims 3
- 206010013700 Drug hypersensitivity Diseases 0.000 claims 2
- 208000004262 Food Hypersensitivity Diseases 0.000 claims 2
- 206010016946 Food allergy Diseases 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 2
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 claims 2
- 206010039085 Rhinitis allergic Diseases 0.000 claims 2
- 239000013567 aeroallergen Substances 0.000 claims 2
- 201000010105 allergic rhinitis Diseases 0.000 claims 2
- 208000006673 asthma Diseases 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 201000005311 drug allergy Diseases 0.000 claims 2
- 239000000428 dust Substances 0.000 claims 2
- 235000020932 food allergy Nutrition 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 239000003960 organic solvent Substances 0.000 claims 2
- 229960000502 poloxamer Drugs 0.000 claims 2
- 229920001983 poloxamer Polymers 0.000 claims 2
- 229950008882 polysorbate Drugs 0.000 claims 2
- 229920000136 polysorbate Polymers 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 241000238876 Acari Species 0.000 claims 1
- 241001674044 Blattodea Species 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- 239000013566 allergen Substances 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Claims (9)
- ナノエマルジョンと、１つ以上のエアロアレルゲンとを含む組成物。
- １つ以上の前記エアロアレルゲンを、花粉、カビ胞子、食物、ダニ、ゴキブリアレルゲン、動物の毛、動物の尿、粉塵、及び化粧品から選択する、請求項１に記載の組成物。
- 前記ナノエマルジョンが：
（ａ）ポロキサマー界面活性剤、またはポリソルベート界面活性剤；
（ｂ）有機溶媒；
（ｃ）ハロゲン含有化合物；
（ｄ）油、及び
（ｅ）水、を含む、請求項１または請求項２に記載の組成物。 - 前記ナノエマルジョンが；
ａ）約３体積％～約１５体積％のポロキサマー界面活性剤、またはポリソルベート界面活性剤；
ｂ）約３体積％～約１５体積％の有機溶媒；
ｃ）約０．５体積％～約１体積％のハロゲン含有化合物；
ｄ）約３体積％～約９０体積％の油；及び
ｅ）約５体積％～約６０体積％の水、
を含む、請求項３に記載の組成物。 - 気道炎症の治療のための薬の製造方法における請求項１～４のいずれか１項に記載の組成物の有効量の使用。
- 前記気道炎症は、喘息、アレルギー性鼻炎、食物アレルギー、または薬物アレルギーに関連している、請求項５に記載の使用。
- 前記組成物はＴｈ２型サイトカインの発現を抑制する、請求項５に記載の使用。
- 気道炎症の治療のための請求項１～４のいずれか１項に記載の組成物。
- 前記気道炎症は、喘息、アレルギー性鼻炎、食物アレルギー、または薬物アレルギーに関連している、請求項８に記載の組成物。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962934878P | 2019-11-13 | 2019-11-13 | |
| US62/934,878 | 2019-11-13 | ||
| PCT/US2020/060362 WO2021097174A1 (en) | 2019-11-13 | 2020-11-13 | Nanoemulsion compositions for treating aeroallergen associated allergy and inflammation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023502943A JP2023502943A (ja) | 2023-01-26 |
| JPWO2021097174A5 true JPWO2021097174A5 (ja) | 2023-11-21 |
Family
ID=75912616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022528047A Pending JP2023502943A (ja) | 2019-11-13 | 2020-11-13 | エアロアレルゲン関連アレルギーと炎症とを治療するナノエマルジョン組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220387316A1 (ja) |
| EP (1) | EP4058059A4 (ja) |
| JP (1) | JP2023502943A (ja) |
| CN (1) | CN114929271A (ja) |
| WO (1) | WO2021097174A1 (ja) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022147173A1 (en) * | 2020-12-30 | 2022-07-07 | The Regents Of The University Of Michigan | Nanoemulsion vaccine compositions and methods for suppressing reactivity to multiple food allergens |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006099574A2 (en) * | 2005-03-16 | 2006-09-21 | Tai June Yoo | Cockroach allergen gene expression and delivery systems and uses |
| ES2924988T3 (es) * | 2014-10-10 | 2022-10-13 | Univ Michigan Regents | Composiciones con nanoemulsiones para prevenir, inhibir o eliminar una enfermedad alérgica e inflamatoria |
-
2020
- 2020-11-13 EP EP20888060.9A patent/EP4058059A4/en active Pending
- 2020-11-13 WO PCT/US2020/060362 patent/WO2021097174A1/en unknown
- 2020-11-13 JP JP2022528047A patent/JP2023502943A/ja active Pending
- 2020-11-13 CN CN202080092266.7A patent/CN114929271A/zh active Pending
- 2020-11-13 US US17/775,743 patent/US20220387316A1/en active Pending
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