JPWO2021095875A1 - - Google Patents

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Publication number
JPWO2021095875A1
JPWO2021095875A1 JP2021556192A JP2021556192A JPWO2021095875A1 JP WO2021095875 A1 JPWO2021095875 A1 JP WO2021095875A1 JP 2021556192 A JP2021556192 A JP 2021556192A JP 2021556192 A JP2021556192 A JP 2021556192A JP WO2021095875 A1 JPWO2021095875 A1 JP WO2021095875A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2021556192A
Other languages
Japanese (ja)
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JP7669280B2 (ja
JPWO2021095875A5 (https=
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Publication of JPWO2021095875A1 publication Critical patent/JPWO2021095875A1/ja
Publication of JPWO2021095875A5 publication Critical patent/JPWO2021095875A5/ja
Priority to JP2025067244A priority Critical patent/JP2025111536A/ja
Application granted granted Critical
Publication of JP7669280B2 publication Critical patent/JP7669280B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2021556192A 2019-11-13 2020-11-13 オリゴ核酸化合物の製造方法 Active JP7669280B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025067244A JP2025111536A (ja) 2019-11-13 2025-04-16 オリゴ核酸化合物の製造方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019205628 2019-11-13
JP2019205628 2019-11-13
PCT/JP2020/042506 WO2021095875A1 (ja) 2019-11-13 2020-11-13 オリゴ核酸化合物の製造方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025067244A Division JP2025111536A (ja) 2019-11-13 2025-04-16 オリゴ核酸化合物の製造方法

Publications (3)

Publication Number Publication Date
JPWO2021095875A1 true JPWO2021095875A1 (https=) 2021-05-20
JPWO2021095875A5 JPWO2021095875A5 (https=) 2023-11-16
JP7669280B2 JP7669280B2 (ja) 2025-04-28

Family

ID=75912390

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021556192A Active JP7669280B2 (ja) 2019-11-13 2020-11-13 オリゴ核酸化合物の製造方法
JP2025067244A Pending JP2025111536A (ja) 2019-11-13 2025-04-16 オリゴ核酸化合物の製造方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025067244A Pending JP2025111536A (ja) 2019-11-13 2025-04-16 オリゴ核酸化合物の製造方法

Country Status (7)

Country Link
US (1) US12600744B2 (https=)
EP (1) EP4059943A4 (https=)
JP (2) JP7669280B2 (https=)
KR (1) KR20220097986A (https=)
CN (1) CN114981280A (https=)
CA (1) CA3161589A1 (https=)
WO (1) WO2021095875A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240254158A1 (en) * 2021-04-28 2024-08-01 Nippon Shinyaku Co., Ltd. Method for producing oligonucleic acid compound
CA3244382A1 (en) * 2021-12-27 2025-02-26 Nippon Shinyaku Co., Ltd. PROCESS FOR THE PRODUCTION OF OLIGONUCLEIC ACID COMPOUNDS

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002517404A (ja) * 1998-06-02 2002-06-18 アイシス・ファーマシューティカルス・インコーポレーテッド オリゴヌクレオチド合成のためのアクチベーター
US20100234281A1 (en) * 2005-07-13 2010-09-16 Weller Dwight D Antibacterial antisense oligonucleotide and method
JP2015500204A (ja) * 2011-11-18 2015-01-05 サレプタ セラピューティクス， インコーポレイテッド 機能的に修飾されたオリゴヌクレオチドおよびそのサブユニット

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2130844A5 (https=) 1971-03-23 1972-11-10 Commissariat Energie Atomique
JPS5668388A (en) 1979-11-10 1981-06-09 Norin Suisansyo Shokuhin Sogo Kenkyusho Production of cell body of spirulina algae
JP3398378B2 (ja) 1989-12-20 2003-04-21 アンチビラルス・インコーポレイテツド リン含有キラルインターサブユニットリンケージを有する非電荷モルホリノ―基体ポリマー
US6313301B1 (en) 1997-08-13 2001-11-06 Takeda Chemical Industries, Ltd. Thienopyridine derivatives, their intermediates and production thereof
JP2005529957A (ja) 2002-06-13 2005-10-06 ローディア インク． リン・ジアミダイト合成物を生成する工程
KR100886139B1 (ko) 2007-11-13 2009-02-27 주식회사 삼천리제약 올리고뉴클레오타이드의 제조방법
MX2010004955A (es) 2007-11-15 2010-06-30 Avi Biopharma Inc Metodo de sintesis de oligomeros de morfolina.
JP5548852B2 (ja) 2009-05-29 2014-07-16 国立大学法人東京農工大学 疎水性基結合ヌクレオシド、疎水性基結合ヌクレオシド溶液、及び疎水性基結合オリゴヌクレオチド合成方法
RS55610B1 (sr) 2010-09-30 2017-06-30 Nippon Shinyaku Co Ltd Derivat morfolino nukleinske kiseline
JP5979139B2 (ja) 2011-05-17 2016-08-24 味の素株式会社 オリゴヌクレオチドの製造方法
US10066228B2 (en) 2011-11-30 2018-09-04 Sarepta Therapeutics, Inc. Oligonucleotides for treating expanded repeat diseases
EP2816053B1 (en) 2012-02-17 2021-03-24 Ajinomoto Co., Inc. Base-protected oligonucleotide
EP2921499B1 (en) 2012-11-14 2020-01-22 Takeda Pharmaceutical Company Limited Method for liquid-phase synthesis of nucleic acids
WO2014189142A1 (ja) 2013-05-24 2014-11-27 味の素株式会社 モルフォリノオリゴヌクレオチドの製造方法
JP6673211B2 (ja) 2014-10-14 2020-03-25 味の素株式会社 モルフォリノオリゴヌクレオチドの製造方法
EP3266792B1 (en) 2015-03-04 2020-12-30 Jitsubo Co., Ltd. Peptide synthesis method
JP2019534862A (ja) * 2016-09-20 2019-12-05 ザ リージェンツ オブ ザ ユニヴァーシティ オブ コロラド，ア ボディ コーポレイト ホスホルアミダイト化学を使用する骨格修飾モルホリノオリゴヌクレオチド及びキメラの合成
CN112384520B (zh) * 2018-05-10 2024-06-11 日本新药株式会社 寡核苷酸化合物的制造方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002517404A (ja) * 1998-06-02 2002-06-18 アイシス・ファーマシューティカルス・インコーポレーテッド オリゴヌクレオチド合成のためのアクチベーター
US20100234281A1 (en) * 2005-07-13 2010-09-16 Weller Dwight D Antibacterial antisense oligonucleotide and method
JP2015500204A (ja) * 2011-11-18 2015-01-05 サレプタ セラピューティクス， インコーポレイテッド 機能的に修飾されたオリゴヌクレオチドおよびそのサブユニット

Also Published As

Publication number Publication date
CN114981280A (zh) 2022-08-30
CA3161589A1 (en) 2021-05-20
EP4059943A4 (en) 2024-01-31
US12600744B2 (en) 2026-04-14
US20230014840A1 (en) 2023-01-19
EP4059943A1 (en) 2022-09-21
JP7669280B2 (ja) 2025-04-28
JP2025111536A (ja) 2025-07-30
WO2021095875A1 (ja) 2021-05-20
KR20220097986A (ko) 2022-07-08

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