JPWO2021095875A1 - - Google Patents

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Publication number
JPWO2021095875A1
JPWO2021095875A1 JP2021556192A JP2021556192A JPWO2021095875A1 JP WO2021095875 A1 JPWO2021095875 A1 JP WO2021095875A1 JP 2021556192 A JP2021556192 A JP 2021556192A JP 2021556192 A JP2021556192 A JP 2021556192A JP WO2021095875 A1 JPWO2021095875 A1 JP WO2021095875A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2021556192A
Other languages
Japanese (ja)
Other versions
JPWO2021095875A5 (https=
JP7669280B2 (ja
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Publication of JPWO2021095875A1 publication Critical patent/JPWO2021095875A1/ja
Publication of JPWO2021095875A5 publication Critical patent/JPWO2021095875A5/ja
Priority to JP2025067244A priority Critical patent/JP2025111536A/ja
Application granted granted Critical
Publication of JP7669280B2 publication Critical patent/JP7669280B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2021556192A 2019-11-13 2020-11-13 オリゴ核酸化合物の製造方法 Active JP7669280B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025067244A JP2025111536A (ja) 2019-11-13 2025-04-16 オリゴ核酸化合物の製造方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019205628 2019-11-13
JP2019205628 2019-11-13
PCT/JP2020/042506 WO2021095875A1 (ja) 2019-11-13 2020-11-13 オリゴ核酸化合物の製造方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025067244A Division JP2025111536A (ja) 2019-11-13 2025-04-16 オリゴ核酸化合物の製造方法

Publications (3)

Publication Number Publication Date
JPWO2021095875A1 true JPWO2021095875A1 (https=) 2021-05-20
JPWO2021095875A5 JPWO2021095875A5 (https=) 2023-11-16
JP7669280B2 JP7669280B2 (ja) 2025-04-28

Family

ID=75912390

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021556192A Active JP7669280B2 (ja) 2019-11-13 2020-11-13 オリゴ核酸化合物の製造方法
JP2025067244A Pending JP2025111536A (ja) 2019-11-13 2025-04-16 オリゴ核酸化合物の製造方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025067244A Pending JP2025111536A (ja) 2019-11-13 2025-04-16 オリゴ核酸化合物の製造方法

Country Status (7)

Country Link
US (1) US12600744B2 (https=)
EP (1) EP4059943A4 (https=)
JP (2) JP7669280B2 (https=)
KR (1) KR20220097986A (https=)
CN (1) CN114981280A (https=)
CA (1) CA3161589A1 (https=)
WO (1) WO2021095875A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7825613B2 (ja) * 2021-04-28 2026-03-06 日本新薬株式会社 オリゴ核酸化合物の製造方法
EP4458833A4 (en) * 2021-12-27 2025-12-31 Nippon Shinyaku Co Ltd PROCESS FOR THE PRODUCTION OF OLIGONUCLEIC ACID COMPOUNDS

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002517404A (ja) * 1998-06-02 2002-06-18 アイシス・ファーマシューティカルス・インコーポレーテッド オリゴヌクレオチド合成のためのアクチベーター
US20100234281A1 (en) * 2005-07-13 2010-09-16 Weller Dwight D Antibacterial antisense oligonucleotide and method
JP2015500204A (ja) * 2011-11-18 2015-01-05 サレプタ セラピューティクス， インコーポレイテッド 機能的に修飾されたオリゴヌクレオチドおよびそのサブユニット

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2130844A5 (https=) 1971-03-23 1972-11-10 Commissariat Energie Atomique
JPS5668388A (en) 1979-11-10 1981-06-09 Norin Suisansyo Shokuhin Sogo Kenkyusho Production of cell body of spirulina algae
AU655164B2 (en) 1989-12-20 1994-12-08 Antivirals Inc. Uncharged morpholino-based polymers having phosphorous-containing chiral intersubunit linkages
US6313301B1 (en) 1997-08-13 2001-11-06 Takeda Chemical Industries, Ltd. Thienopyridine derivatives, their intermediates and production thereof
CN100338076C (zh) 2002-06-13 2007-09-19 罗狄亚公司 制备亚磷酰二胺化合物的方法
KR100886139B1 (ko) 2007-11-13 2009-02-27 주식회사 삼천리제약 올리고뉴클레오타이드의 제조방법
RU2606627C2 (ru) 2007-11-15 2017-01-10 Серепта Терапьютикс,Инк. Способ синтеза морфолиновых олигомеров
JP5548852B2 (ja) 2009-05-29 2014-07-16 国立大学法人東京農工大学 疎水性基結合ヌクレオシド、疎水性基結合ヌクレオシド溶液、及び疎水性基結合オリゴヌクレオチド合成方法
ES2607603T3 (es) 2010-09-30 2017-04-03 Nippon Shinyaku Co., Ltd. Derivado de ácido morfolino nucleico
DK2711370T3 (en) 2011-05-17 2018-02-26 Ajinomoto Kk PROCEDURE FOR THE PREPARATION OF OLIGONUCLEOTIDES
US10066228B2 (en) 2011-11-30 2018-09-04 Sarepta Therapeutics, Inc. Oligonucleotides for treating expanded repeat diseases
EP2816053B1 (en) 2012-02-17 2021-03-24 Ajinomoto Co., Inc. Base-protected oligonucleotide
US10214555B2 (en) 2012-11-14 2019-02-26 Takeda Pharmaceutical Company Limitjed Method for liquid-phase synthesis of nucleic acid
DK3015467T3 (da) 2013-05-24 2025-02-10 Ajinomoto Kk Morpholino-oligonukleotidfremstillingsfremgangsmåde
WO2016060135A1 (ja) 2014-10-14 2016-04-21 味の素株式会社 モルフォリノオリゴヌクレオチドの製造方法
CN107406480B (zh) 2015-03-04 2022-06-24 Jitsubo株式会社 肽合成方法
AU2017330276B2 (en) 2016-09-20 2022-01-20 The Regents Of The University Of Colorado, A Body Corporate Synthesis of backbone modified morpholino oligonucleotides and chimeras using phosphoramidite chemistry
CA3099778A1 (en) * 2018-05-10 2019-11-14 Nippon Shinyaku Co., Ltd. Method for preparing oligonucleic acid compound

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002517404A (ja) * 1998-06-02 2002-06-18 アイシス・ファーマシューティカルス・インコーポレーテッド オリゴヌクレオチド合成のためのアクチベーター
US20100234281A1 (en) * 2005-07-13 2010-09-16 Weller Dwight D Antibacterial antisense oligonucleotide and method
JP2015500204A (ja) * 2011-11-18 2015-01-05 サレプタ セラピューティクス， インコーポレイテッド 機能的に修飾されたオリゴヌクレオチドおよびそのサブユニット

Also Published As

Publication number Publication date
JP2025111536A (ja) 2025-07-30
EP4059943A1 (en) 2022-09-21
US12600744B2 (en) 2026-04-14
WO2021095875A1 (ja) 2021-05-20
KR20220097986A (ko) 2022-07-08
US20230014840A1 (en) 2023-01-19
JP7669280B2 (ja) 2025-04-28
CA3161589A1 (en) 2021-05-20
EP4059943A4 (en) 2024-01-31
CN114981280A (zh) 2022-08-30

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