JPWO2021084419A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2021084419A5 JPWO2021084419A5 JP2022551433A JP2022551433A JPWO2021084419A5 JP WO2021084419 A5 JPWO2021084419 A5 JP WO2021084419A5 JP 2022551433 A JP2022551433 A JP 2022551433A JP 2022551433 A JP2022551433 A JP 2022551433A JP WO2021084419 A5 JPWO2021084419 A5 JP WO2021084419A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- rca
- grid oligonucleotide
- grid
- products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962926907P | 2019-10-28 | 2019-10-28 | |
| US62/926,907 | 2019-10-28 | ||
| PCT/IB2020/060062 WO2021084419A1 (en) | 2019-10-28 | 2020-10-27 | Method for mapping rolling circle amplification products |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022554421A JP2022554421A (ja) | 2022-12-28 |
| JPWO2021084419A5 true JPWO2021084419A5 (https=) | 2023-10-30 |
| JP2022554421A5 JP2022554421A5 (https=) | 2023-10-30 |
| JP7684984B2 JP7684984B2 (ja) | 2025-05-28 |
Family
ID=73172763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022551433A Active JP7684984B2 (ja) | 2019-10-28 | 2020-10-27 | ローリングサークル増幅産物をマッピングするための方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US12252741B2 (https=) |
| EP (1) | EP4051810B1 (https=) |
| JP (1) | JP7684984B2 (https=) |
| CN (1) | CN114616344B (https=) |
| AU (1) | AU2020375212B2 (https=) |
| CA (1) | CA3157211A1 (https=) |
| DK (1) | DK4051810T3 (https=) |
| WO (1) | WO2021084419A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022032195A2 (en) | 2020-08-06 | 2022-02-10 | Singular Genomics Systems, Inc. | Spatial sequencing |
| EP4121561A4 (en) | 2020-08-06 | 2024-04-17 | Singular Genomics Systems, Inc. | Methods for in situ transcriptomics and proteomics |
| EP4303315B1 (en) | 2021-03-30 | 2024-11-06 | Pixelgen Technologies Ab | Spatial mapping by serial primer extension |
| EP4720332A1 (en) | 2023-06-01 | 2026-04-08 | Singular Genomics Systems, Inc. | Methods and probes for detecting polynucleotide sequences in cells and tissues |
| WO2025158200A1 (en) | 2024-01-25 | 2025-07-31 | Pixelgen Technologies Ab | Method for spatial mapping of cell targets |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5948902A (en) | 1997-11-20 | 1999-09-07 | South Alabama Medical Science Foundation | Antisense oligonucleotides to human serine/threonine protein phosphatase genes |
| US20050118616A1 (en) * | 2002-08-16 | 2005-06-02 | Kawashima Tadashi R. | Amplification of target nucleotide sequence without polymerase chain reaction |
| AU2004232976B2 (en) * | 2003-04-18 | 2011-02-10 | Becton, Dickinson And Company | Immuno-amplification |
| US20050233340A1 (en) | 2004-04-20 | 2005-10-20 | Barrett Michael T | Methods and compositions for assessing CpG methylation |
| US8916351B2 (en) * | 2005-01-04 | 2014-12-23 | Hitachi Chemical Co., Ltd. | Primer generation rolling circle amplification |
| US8481698B2 (en) | 2009-03-19 | 2013-07-09 | The President And Fellows Of Harvard College | Parallel proximity ligation event analysis |
| EP2633081B1 (en) * | 2010-10-29 | 2017-01-11 | Olink Bioscience AB | Proximity ligation technology for western blot applications |
| JP6069224B2 (ja) | 2011-01-31 | 2017-02-01 | アプライズ バイオ, インコーポレイテッド | 細胞において複数のエピトープを同定する方法 |
| EP3736281A1 (en) | 2011-02-18 | 2020-11-11 | Bio-Rad Laboratories, Inc. | Compositions and methods for molecular labeling |
| GB201201547D0 (en) | 2012-01-30 | 2012-03-14 | Olink Ab | Method and product |
| WO2014076209A1 (en) * | 2012-11-14 | 2014-05-22 | Olink Ab | Localised rca-based amplification method |
| CN105745334B (zh) * | 2013-09-30 | 2019-12-10 | 吴迪 | 通过使用邻近条形编码分析分子复合物的概况的方法 |
| EP3058091B1 (en) | 2013-10-18 | 2020-03-25 | The Broad Institute, Inc. | Spatial and cellular mapping of biomolecules in situ by high-throughput sequencing |
| GB201320145D0 (en) * | 2013-11-14 | 2014-01-01 | Olink Ab | Localised RCA-based amplification method using a padlock-probe |
| US20150298091A1 (en) | 2014-04-21 | 2015-10-22 | President And Fellows Of Harvard College | Systems and methods for barcoding nucleic acids |
| US9909167B2 (en) * | 2014-06-23 | 2018-03-06 | The Board Of Trustees Of The Leland Stanford Junior University | On-slide staining by primer extension |
| ES2891085T3 (es) | 2015-01-30 | 2022-01-26 | Harvard College | Obtención de imágenes sin microscopio |
| WO2017044893A1 (en) | 2015-09-11 | 2017-03-16 | The Broad Institute, Inc. | Dna microscopy |
| US11092607B2 (en) * | 2015-10-28 | 2021-08-17 | The Board Institute, Inc. | Multiplex analysis of single cell constituents |
| EP4050112A1 (en) | 2016-06-21 | 2022-08-31 | 10X Genomics, Inc. | Nucleic acid sequencing |
| EP3583214B1 (en) * | 2017-02-02 | 2023-11-22 | New York Genome Center, Inc. | Methods and compositions for identifying or quantifying targets in a biological sample |
| GB201718681D0 (en) * | 2017-11-13 | 2017-12-27 | Evox Therapeutics Ltd | Protein engineered extracellular vesicles |
| EP3954782A1 (en) | 2017-11-15 | 2022-02-16 | 10X Genomics, Inc. | Functionalized gel beads |
| EP4477758B1 (en) | 2018-11-30 | 2026-04-22 | Illumina, Inc. | Analysis of multiple analytes using a single assay |
| CN114787348B (zh) | 2019-09-30 | 2025-09-19 | 耶鲁大学 | 用于空间组学测序的确定性条形码 |
-
2020
- 2020-10-27 US US17/763,145 patent/US12252741B2/en active Active
- 2020-10-27 EP EP20803646.7A patent/EP4051810B1/en active Active
- 2020-10-27 AU AU2020375212A patent/AU2020375212B2/en active Active
- 2020-10-27 CN CN202080075923.7A patent/CN114616344B/zh active Active
- 2020-10-27 WO PCT/IB2020/060062 patent/WO2021084419A1/en not_active Ceased
- 2020-10-27 CA CA3157211A patent/CA3157211A1/en active Pending
- 2020-10-27 JP JP2022551433A patent/JP7684984B2/ja active Active
- 2020-10-27 DK DK20803646.7T patent/DK4051810T3/da active
-
2025
- 2025-02-10 US US19/049,977 patent/US20250305038A1/en active Pending
- 2025-05-19 US US19/212,481 patent/US12404545B1/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6925424B2 (ja) | 短いdna断片を連結することによる一分子シーケンスのスループットを増加する方法 | |
| US8986958B2 (en) | Methods for generating target specific probes for solution based capture | |
| CN107208144B (zh) | 无酶且无扩增的测序 | |
| EP2191011B1 (en) | Method for sequencing a polynucleotide template | |
| US20050112636A1 (en) | Polymeric nucleic acid hybridization probes | |
| US20030082576A1 (en) | High throughput polymorphism screening | |
| US20100092972A1 (en) | Assay for gene expression | |
| JP2018503403A (ja) | 液相におけるライゲーションアッセイ | |
| US10174352B2 (en) | Methods for amplification of nucleic acids on solid support | |
| KR20160138579A (ko) | 게놈 및 치료학적 적용을 위한 핵산 분자의 클론 복제 및 증폭을 위한 시스템 및 방법 | |
| JP2013524841A (ja) | 一本鎖オーバーハングを有する二本鎖核酸を生成するための方法 | |
| JPWO2021084419A5 (https=) | ||
| CA3220708A1 (en) | Oligo-modified nucleotide analogues for nucleic acid preparation | |
| CN107109478B (zh) | 获得配对末端测序信息的方法 | |
| JP2006508677A (ja) | 遺伝子発現のオリゴヌクレオチド誘導分析 | |
| Myllykangas et al. | Targeted sequencing library preparation by genomic DNA circularization | |
| WO2000029624A2 (en) | Methods and compositions for detection of nucleic acid sequences and signal amplification | |
| WO2023116373A1 (zh) | 一种生成标记的核酸分子群的方法及其试剂盒 | |
| US20250369045A1 (en) | Multivalent assemblies for enhanced target hybridization | |
| WO2023115536A1 (zh) | 一种生成标记的核酸分子群的方法及其试剂盒 | |
| JP7610617B2 (ja) | 反応混合物からの過剰なオリゴヌクレオチドの除去 | |
| EP4431450A1 (en) | Supporter for sequencing target nucleic acid strands | |
| RU2809771C2 (ru) | Композиции и способы для улучшения обогащения библиотек | |
| WO2023116376A1 (zh) | 单细胞核酸标记和分析方法 | |
| JP2024506277A (ja) | 脱塩基核酸を有する配列変換及びシグナル増幅dna、並びにそれを使用する検出方法 |