JPWO2021049633A5 - - Google Patents

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Publication number
JPWO2021049633A5
JPWO2021049633A5 JP2021545626A JP2021545626A JPWO2021049633A5 JP WO2021049633 A5 JPWO2021049633 A5 JP WO2021049633A5 JP 2021545626 A JP2021545626 A JP 2021545626A JP 2021545626 A JP2021545626 A JP 2021545626A JP WO2021049633 A5 JPWO2021049633 A5 JP WO2021049633A5
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JP
Japan
Prior art keywords
collagen
mutation
group
secretion
cyclophilin
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021545626A
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English (en)
Japanese (ja)
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JPWO2021049633A1 (https=
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Publication date
Application filed filed Critical
Priority claimed from PCT/JP2020/034538 external-priority patent/WO2021049633A1/ja
Publication of JPWO2021049633A1 publication Critical patent/JPWO2021049633A1/ja
Publication of JPWO2021049633A5 publication Critical patent/JPWO2021049633A5/ja
Pending legal-status Critical Current

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JP2021545626A 2019-09-11 2020-09-11 Pending JPWO2021049633A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2019165583 2019-09-11
PCT/JP2020/034538 WO2021049633A1 (ja) 2019-09-11 2020-09-11 難治性遺伝性腎疾患アルポート症候群の根治療法のための薬剤

Publications (2)

Publication Number Publication Date
JPWO2021049633A1 JPWO2021049633A1 (https=) 2021-03-18
JPWO2021049633A5 true JPWO2021049633A5 (https=) 2023-09-20

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ID=74865760

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021545626A Pending JPWO2021049633A1 (https=) 2019-09-11 2020-09-11

Country Status (5)

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US (1) US20230082311A1 (https=)
EP (1) EP4029514A4 (https=)
JP (1) JPWO2021049633A1 (https=)
CN (1) CN114761033A (https=)
WO (1) WO2021049633A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113981000B (zh) * 2021-08-24 2023-04-25 四川大学华西医院 一种COL4A3 p.P408H基因点突变小鼠模型及其构建方法、应用和试剂盒
JP2024541719A (ja) * 2021-11-18 2024-11-11 レゾナンス ヘルス アナリシス サービシーズ ピーティーワイ リミテッド シクロフィリンd関連疾患の処置方法
CN117720619B (zh) * 2023-05-16 2024-10-29 杭州禾泰健宇生物科技有限公司 一种多肽、抗光老化多肽及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009018179A2 (en) 2007-07-27 2009-02-05 Columbia University Cyclophilin d-amyloid beta interaction potentiates mitochondrial dysfunction in a transgenic mouse model of alzheimer's disease
US20140050728A1 (en) * 2011-01-28 2014-02-20 Board Of Regents Of The University Of Nebraska Methods and compositions for inhibiting cyclophilin d for the treatment and prevention of obesity and kidney indications
US9132138B2 (en) 2012-08-27 2015-09-15 Casi Pharmaceuticals, Inc. Method for the treatment of multiple sclerosis
US9833467B2 (en) 2012-12-12 2017-12-05 University Of Rochester Use of cyclophilin D inhibitors to treat or prevent bone disorders
EP3131569B1 (en) 2014-04-16 2020-05-27 Philippe Rouet Apoo for use in a method for treating cancer and various pathophysiological situations
EP3164148A4 (en) 2014-06-25 2017-12-13 Cold Spring Harbor Laboratory Methods and compositions for inhibiting growth and epithelial to mesenchymal transition (emt) in cancer cells
WO2016014781A1 (en) * 2014-07-25 2016-01-28 Rgdi3, Inc. Collagen iv replacement
US9738615B2 (en) 2014-09-11 2017-08-22 The University Of Kansas Cyclophilin D inhibitors
JP2016124821A (ja) 2014-12-26 2016-07-11 学校法人東京医科大学 敗血症性脳症用医薬
US9914755B2 (en) * 2015-01-08 2018-03-13 Allergan, Inc. Cyclosporin derivatives wherein the MeBmt sidechain has been cyclized
US10179161B2 (en) 2016-02-22 2019-01-15 The University Of Rochester Compositions and methods for enhancing cardiac function in the neonate
JP6990369B2 (ja) * 2017-05-19 2022-02-03 国立大学法人 熊本大学 遺伝性腎疾患アルポート症候群治療薬に係る評価系
CN112469433A (zh) 2018-03-05 2021-03-09 得克萨斯农业及机械体系综合大学 作为免疫抑制剂和神经保护剂的gracilin A和同源物

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