JPWO2021020845A5 - - Google Patents

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Publication number
JPWO2021020845A5
JPWO2021020845A5 JP2022504629A JP2022504629A JPWO2021020845A5 JP WO2021020845 A5 JPWO2021020845 A5 JP WO2021020845A5 JP 2022504629 A JP2022504629 A JP 2022504629A JP 2022504629 A JP2022504629 A JP 2022504629A JP WO2021020845 A5 JPWO2021020845 A5 JP WO2021020845A5
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JP
Japan
Prior art keywords
egfr
amino acid
seq
acid sequence
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2022504629A
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English (en)
Japanese (ja)
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JP2022542670A (ja
JP2022542670A5 (https=
JP7738545B2 (ja
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Priority claimed from PCT/KR2020/009870 external-priority patent/WO2021020845A1/en
Publication of JP2022542670A publication Critical patent/JP2022542670A/ja
Publication of JP2022542670A5 publication Critical patent/JP2022542670A5/ja
Publication of JPWO2021020845A5 publication Critical patent/JPWO2021020845A5/ja
Priority to JP2025145010A priority Critical patent/JP2026004296A/ja
Application granted granted Critical
Publication of JP7738545B2 publication Critical patent/JP7738545B2/ja
Active legal-status Critical Current
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JP2022504629A 2019-07-26 2020-07-27 抗egfr/抗4-1bb二重特異性抗体及びその使用 Active JP7738545B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025145010A JP2026004296A (ja) 2019-07-26 2025-09-02 抗egfr/抗4-1bb二重特異性抗体及びその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962878977P 2019-07-26 2019-07-26
US62/878,977 2019-07-26
PCT/KR2020/009870 WO2021020845A1 (en) 2019-07-26 2020-07-27 Anti-egfr/anti-4-1bb bispecific antibody and use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025145010A Division JP2026004296A (ja) 2019-07-26 2025-09-02 抗egfr/抗4-1bb二重特異性抗体及びその使用

Publications (4)

Publication Number Publication Date
JP2022542670A JP2022542670A (ja) 2022-10-06
JP2022542670A5 JP2022542670A5 (https=) 2023-08-03
JPWO2021020845A5 true JPWO2021020845A5 (https=) 2023-08-03
JP7738545B2 JP7738545B2 (ja) 2025-09-12

Family

ID=74189704

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022504629A Active JP7738545B2 (ja) 2019-07-26 2020-07-27 抗egfr/抗4-1bb二重特異性抗体及びその使用
JP2025145010A Pending JP2026004296A (ja) 2019-07-26 2025-09-02 抗egfr/抗4-1bb二重特異性抗体及びその使用

Family Applications After (1)

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JP2025145010A Pending JP2026004296A (ja) 2019-07-26 2025-09-02 抗egfr/抗4-1bb二重特異性抗体及びその使用

Country Status (11)

Country Link
US (2) US12168690B2 (https=)
EP (1) EP4004053A4 (https=)
JP (2) JP7738545B2 (https=)
KR (1) KR20220038767A (https=)
CN (2) CN118221825A (https=)
AU (1) AU2020320349A1 (https=)
BR (1) BR112022001329A2 (https=)
CA (1) CA3147420A1 (https=)
MX (1) MX2022001027A (https=)
WO (1) WO2021020845A1 (https=)
ZA (1) ZA202200905B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20211147A1 (es) 2019-08-12 2021-06-28 I Mab Biopharma Us Ltd Anticuerpos anti-claudina 18.2 y anti-4-1bb biespecificos y su uso
EP4434548A1 (en) 2021-11-15 2024-09-25 Systimmune, Inc. Bispecific antibody-camptothecin drug conjugate and pharmaceutical use thereof
US20250320309A1 (en) * 2021-11-25 2025-10-16 Shenghe (China) Biopharmaceutical Co., Ltd. Bispecific antigen binding protein
JP2025512915A (ja) * 2022-04-07 2025-04-22 ユハン コーポレーション Her2の発現レベルが低いがんを治療又は予防するための薬学的組成物
JP2025542406A (ja) * 2022-12-30 2025-12-25 アブクロン・インコーポレイテッド Cd137に特異的に結合するアフィボディ及びその用途
KR20240164748A (ko) * 2023-05-12 2024-11-20 앱클론(주) 항체 또는 그의 항원 결합 단편, 및 어피바디를 포함하는 이중 항원 표적 단백질 복합체
KR102927129B1 (ko) 2025-03-18 2026-02-11 이트너스 주식회사 임직원 공간 산정을 위한 사무 및 부대 시설 면적 계산 솔루션

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2185770T3 (es) * 1995-04-08 2003-05-01 Lg Chemical Ltd Anticuerpo monoclonal especifico para 4-1bb humano y linea celular que lo produce.
US7288638B2 (en) 2003-10-10 2007-10-30 Bristol-Myers Squibb Company Fully human antibodies against human 4-1BB
AU2006211037B2 (en) 2005-02-07 2012-05-24 Roche Glycart Ag Antigen binding molecules that bind EGFR, vectors encoding same, and uses thereof
SI2073842T1 (sl) * 2006-09-10 2015-05-29 Glycotope Gmbh Uporaba človeških celic izvirajočih iz mieloične levkemije za izražanje protiteles
DK2699598T3 (en) * 2011-04-19 2019-04-23 Pfizer COMBINATIONS OF ANTI-4-1BB ANTIBODIES AND ADCC-INducing ANTIBODIES FOR TREATMENT OF CANCER
JP6539275B2 (ja) * 2013-08-16 2019-07-03 メモリアル スローン ケタリング キャンサー センター 選択的grp94阻害剤およびその使用
SG11201704741PA (en) * 2014-12-22 2017-07-28 Systimmune Inc Bispecific tetravalent antibodies and methods of makiing and using thereof
EP3356401B1 (en) 2015-09-30 2020-06-24 IGM Biosciences, Inc. Binding molecules with modified j-chain
FI3436048T3 (fi) 2016-03-31 2025-09-15 Biontech Us Inc Neoantigeeneja ja niiden käyttömenetelmiä
AU2017252233A1 (en) * 2016-04-22 2018-11-15 Alligator Bioscience Ab Novel bispecific polypeptides against CD137
CN118267470A (zh) * 2017-04-13 2024-07-02 赛罗帕私人有限公司 抗SIRPα抗体
SG11202000503QA (en) * 2017-07-20 2020-02-27 Aptevo Res & Development Llc Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods
WO2019129644A1 (en) * 2017-12-28 2019-07-04 Julius-Maximilians-Universität Würzburg TUMOR NECROSIS FACTOR (TNF) RECEPTOR SUPERFAMILY (TNFRSF) RECEPTOR-ACTIVATING ANTIBODY FUSION PROTEINS WITH FcγR-INDEPENDENT AGONISTIC ACTIVITY (TNFRSF RECEPTOR-ACTIVATING ANTIBODY FUSION PROTEINS WITH FCγR-INDEPENDENT AGONISTIC ACTIVITY; TRAAFFIAA)
CN119798453A (zh) * 2018-11-13 2025-04-11 Jn生物科学有限责任公司 激活免疫细胞的双特异性抗体
CN113286825B (zh) * 2018-11-30 2024-06-18 爱必乐生物公司 抗pd-l1/抗4-1bb双特异性抗体及其用途
PE20211147A1 (es) * 2019-08-12 2021-06-28 I Mab Biopharma Us Ltd Anticuerpos anti-claudina 18.2 y anti-4-1bb biespecificos y su uso
CA3169943A1 (en) * 2020-02-28 2021-09-02 Shanghai Henlius Biotech, Inc. Anti-cd137 constructs, multispecific antibody and uses thereof

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