JPWO2021004910A5 - - Google Patents
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- Publication number
- JPWO2021004910A5 JPWO2021004910A5 JP2022500047A JP2022500047A JPWO2021004910A5 JP WO2021004910 A5 JPWO2021004910 A5 JP WO2021004910A5 JP 2022500047 A JP2022500047 A JP 2022500047A JP 2022500047 A JP2022500047 A JP 2022500047A JP WO2021004910 A5 JPWO2021004910 A5 JP WO2021004910A5
- Authority
- JP
- Japan
- Prior art keywords
- jepotidacin
- pharmaceutically acceptable
- doxycycline
- acceptable salt
- mycoplasma genitalium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000015181 infectious disease Diseases 0.000 claims 14
- 229960003722 doxycycline Drugs 0.000 claims 11
- XQTWDDCIUJNLTR-CVHRZJFOSA-N doxycycline monohydrate Chemical compound O.O=C1C2=C(O)C=CC=C2[C@H](C)[C@@H]2C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]1[C@H]2O XQTWDDCIUJNLTR-CVHRZJFOSA-N 0.000 claims 11
- 150000003839 salts Chemical class 0.000 claims 11
- 241000204051 Mycoplasma genitalium Species 0.000 claims 10
- 239000000203 mixture Substances 0.000 claims 10
- 238000000034 method Methods 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 208000035473 Communicable disease Diseases 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 208000000143 urethritis Diseases 0.000 claims 2
- 208000007984 Female Infertility Diseases 0.000 claims 1
- 206010021928 Infertility female Diseases 0.000 claims 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 claims 1
- 241000204003 Mycoplasmatales Species 0.000 claims 1
- 208000007313 Reproductive Tract Infections Diseases 0.000 claims 1
- 208000019802 Sexually transmitted disease Diseases 0.000 claims 1
- 206010042566 Superinfection Diseases 0.000 claims 1
- MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 claims 1
- 229960004099 azithromycin Drugs 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- FABPRXSRWADJSP-MEDUHNTESA-N moxifloxacin Chemical compound COC1=C(N2C[C@H]3NCCC[C@H]3C2)C(F)=CC(C(C(C(O)=O)=C2)=O)=C1N2C1CC1 FABPRXSRWADJSP-MEDUHNTESA-N 0.000 claims 1
- 229960003702 moxifloxacin Drugs 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 208000019206 urinary tract infection Diseases 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962870990P | 2019-07-05 | 2019-07-05 | |
| US62/870,990 | 2019-07-05 | ||
| US202062985465P | 2020-03-05 | 2020-03-05 | |
| US62/985,465 | 2020-03-05 | ||
| PCT/EP2020/068754 WO2021004910A1 (en) | 2019-07-05 | 2020-07-03 | Combination for the treatment of infections caused by mycoplasma genitalium |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022539583A JP2022539583A (ja) | 2022-09-12 |
| JPWO2021004910A5 true JPWO2021004910A5 (https=) | 2023-06-13 |
| JP2022539583A5 JP2022539583A5 (https=) | 2023-06-13 |
| JP7638263B2 JP7638263B2 (ja) | 2025-03-03 |
Family
ID=71579551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022500047A Active JP7638263B2 (ja) | 2019-07-05 | 2020-07-03 | マイコプラズマ・ジェニタリウムによって引き起こされる感染症の治療のための組合せ |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220257615A1 (https=) |
| EP (1) | EP3993796B1 (https=) |
| JP (1) | JP7638263B2 (https=) |
| CN (1) | CN114173789A (https=) |
| BR (1) | BR112021024845A2 (https=) |
| CA (1) | CA3143619A1 (https=) |
| ES (1) | ES2981617T3 (https=) |
| WO (1) | WO2021004910A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11917094B2 (en) * | 2021-02-01 | 2024-02-27 | Aptiv Technologies Limited | Automatic control of smartphone driver mode using ultra-wideband communication |
| CA3210313A1 (en) * | 2021-02-05 | 2022-08-11 | Glaxosmithkline Intellectual Property Development Limited | Oral solid dose formulations |
| CN119546302A (zh) | 2022-09-26 | 2025-02-28 | 葛兰素史密斯克莱知识产权发展有限公司 | 用于治疗细菌性前列腺炎的吉泊达星 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA015821B1 (ru) | 2007-04-20 | 2011-12-30 | Глэксо Груп Лимитед | Трициклические азотсодержащие соединения в качестве антибактериальных агентов |
| RU2675847C2 (ru) | 2013-05-28 | 2018-12-25 | Морфохем Акциенгезельшафт Фюр Комбинаторише Хеми | Комбинированные терапевтические средства, содержащие оксазолидинон-хинолоны, предназначенные для лечения бактериальных инфекций |
| JP6546654B2 (ja) * | 2014-08-22 | 2019-07-17 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited | 淋菌感染を治療するための三環式含窒素化合物 |
| WO2018195098A1 (en) * | 2017-04-17 | 2018-10-25 | Ohio State Innovation Foundation | Type ii topoisomerase inhibitors and methods of making and using thereof |
-
2020
- 2020-07-03 CN CN202080049062.5A patent/CN114173789A/zh active Pending
- 2020-07-03 CA CA3143619A patent/CA3143619A1/en active Pending
- 2020-07-03 JP JP2022500047A patent/JP7638263B2/ja active Active
- 2020-07-03 WO PCT/EP2020/068754 patent/WO2021004910A1/en not_active Ceased
- 2020-07-03 ES ES20739585T patent/ES2981617T3/es active Active
- 2020-07-03 EP EP20739585.6A patent/EP3993796B1/en active Active
- 2020-07-03 US US17/619,367 patent/US20220257615A1/en not_active Abandoned
- 2020-07-03 BR BR112021024845A patent/BR112021024845A2/pt unknown
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