JPWO2020257483A5 - - Google Patents

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Publication number
JPWO2020257483A5
JPWO2020257483A5 JP2021576064A JP2021576064A JPWO2020257483A5 JP WO2020257483 A5 JPWO2020257483 A5 JP WO2020257483A5 JP 2021576064 A JP2021576064 A JP 2021576064A JP 2021576064 A JP2021576064 A JP 2021576064A JP WO2020257483 A5 JPWO2020257483 A5 JP WO2020257483A5
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JP
Japan
Prior art keywords
conjugate
seq
dvd
igg1
bcma
Prior art date
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JP2021576064A
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English (en)
Japanese (ja)
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JP2022538404A (ja
JP7785543B2 (ja
JP2022538404A5 (https=
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Priority claimed from PCT/US2020/038475 external-priority patent/WO2020257483A1/en
Publication of JP2022538404A publication Critical patent/JP2022538404A/ja
Publication of JPWO2020257483A5 publication Critical patent/JPWO2020257483A5/ja
Publication of JP2022538404A5 publication Critical patent/JP2022538404A5/ja
Priority to JP2025225443A priority Critical patent/JP2026041866A/ja
Application granted granted Critical
Publication of JP7785543B2 publication Critical patent/JP7785543B2/ja
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JP2021576064A 2019-06-21 2020-06-18 構造的に明確なｓｉＲＮＡ－二重可変ドメイン免疫グロブリンコンジュゲート Active JP7785543B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025225443A JP2026041866A (ja) 2019-06-21 2025-12-03 構造的に明確なｓｉＲＮＡ－二重可変ドメイン免疫グロブリンコンジュゲート

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962864755P 2019-06-21 2019-06-21
US62/864,755 2019-06-21
PCT/US2020/038475 WO2020257483A1 (en) 2019-06-21 2020-06-18 Structurally defined sirna-dual variable domain immunoglobulin conjugates

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025225443A Division JP2026041866A (ja) 2019-06-21 2025-12-03 構造的に明確なｓｉＲＮＡ－二重可変ドメイン免疫グロブリンコンジュゲート

Publications (4)

Publication Number Publication Date
JP2022538404A JP2022538404A (ja) 2022-09-02
JPWO2020257483A5 true JPWO2020257483A5 (https=) 2023-01-24
JP2022538404A5 JP2022538404A5 (https=) 2023-01-24
JP7785543B2 JP7785543B2 (ja) 2025-12-15

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ID=74040502

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021576064A Active JP7785543B2 (ja) 2019-06-21 2020-06-18 構造的に明確なｓｉＲＮＡ－二重可変ドメイン免疫グロブリンコンジュゲート
JP2025225443A Pending JP2026041866A (ja) 2019-06-21 2025-12-03 構造的に明確なｓｉＲＮＡ－二重可変ドメイン免疫グロブリンコンジュゲート

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025225443A Pending JP2026041866A (ja) 2019-06-21 2025-12-03 構造的に明確なｓｉＲＮＡ－二重可変ドメイン免疫グロブリンコンジュゲート

Country Status (6)

Country Link
US (1) US20230049529A1 (https=)
EP (1) EP3986475A4 (https=)
JP (2) JP7785543B2 (https=)
AU (1) AU2020295485A1 (https=)
CA (1) CA3138627A1 (https=)
WO (1) WO2020257483A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113512557A (zh) * 2021-04-15 2021-10-19 山西大学 飞蝗脱水抗性基因LmDesi及其dsRNA的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4851940B2 (ja) * 2004-11-19 2012-01-11 宮城県 がんまたは糖尿病治療のための医薬組成物
US20110223665A1 (en) * 2008-07-25 2011-09-15 Alnylam Pharmaceuticals, Inc. ENHANCEMENT OF siRNA SILENCING ACTIVITY USING UNIVERSAL BASES OR MISMATCHES IN THE SENSE STRAND
IL316808A (en) * 2014-08-20 2025-01-01 Alnylam Pharmaceuticals Inc Modified double-stranded RNA materials and their uses
CN108025071B (zh) * 2015-09-17 2022-11-01 斯克利普斯研究院 双重可变结构域免疫缀合物及其用途
CA3049133A1 (en) * 2017-01-18 2018-07-26 Alnylam Pharmaceuticals, Inc. Endosomal cleavable linkers

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