JPWO2020244722A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020244722A5 JPWO2020244722A5 JP2021572509A JP2021572509A JPWO2020244722A5 JP WO2020244722 A5 JPWO2020244722 A5 JP WO2020244722A5 JP 2021572509 A JP2021572509 A JP 2021572509A JP 2021572509 A JP2021572509 A JP 2021572509A JP WO2020244722 A5 JPWO2020244722 A5 JP WO2020244722A5
- Authority
- JP
- Japan
- Prior art keywords
- nicotine
- pouch composition
- pouch
- weight
- fiber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Description
また、１０％のＮａＣｌを加えることで、１０分後に得られる放出量が改善されるようである（ＰＰＣ９４）。
本発明のまた別の態様は、以下のとおりであってもよい。
〔１〕
ニコチンパウチ組成物であって：
少なくとも１つの糖アルコールと、
少なくとも１つの水不溶性繊維と、
前記組成物の８～６５重量％の量の水と、
ニコチンと、
を含むニコチンパウチ組成物。
〔２〕
前記組成物は、最大で０．８ｇ／ｃｍ３、例えば最大で０．７ｇ／ｃｍ３など、例えば最大で０．６ｇ／ｃｍ３など、例えば最大で０．５ｇ／ｃｍ３などのかさ密度を有する、前記〔１〕に記載のニコチンパウチ組成物。
〔３〕
前記組成物は、０．２ｇ／ｃｍ３～０．８ｇ／ｃｍ３、例えば０．３ｇ／ｃｍ３～０．７ｇ／ｃｍ３など、例えば０．３ｇ／ｃｍ３～０．６ｇ／ｃｍ３など、例えば０．４～０．５ｇ／ｃｍ３などのかさ密度を有する前記〔１〕または前記〔２〕に記載のニコチンパウチ組成物。
〔４〕
前記ニコチンは、ニコチン塩、ニコチン遊離塩基、ニコチンポラクリレックス樹脂などのイオン交換樹脂などのイオン交換体に結合したニコチン、ニコチン包接複合体または任意の非共有結合のニコチン、ゼオライトに結合したニコチン、微結晶セルロースなどのセルロースに結合したニコチン、またはデンプンマイクロスフェア、およびそれらの混合物からなる群から選択される、前記〔１〕～〔３〕のいずれか一項に記載のニコチンパウチ組成物。
〔５〕
前記ニコチンが非塩ニコチンを含む、前記〔１〕～〔４〕のいずれか一項に記載のニコチンパウチ組成物。
〔６〕
前記ニコチンがニコチン遊離塩基を含む、前記〔１〕～〔５〕のいずれか一項に記載のニコチンパウチ組成物。
〔７〕
前記ニコチンがイオン交換樹脂と混合されたニコチンを含む、前記〔１〕～〔６〕のいずれか一項に記載のニコチンパウチ組成物。
〔８〕
前記ニコチンは、遊離塩基ニコチンとイオン交換樹脂との間の重量比が０．１～２．０、好ましくは０．５～２．０、最も好ましくは約０．６７～１．０で、イオン交換樹脂と混合された遊離塩基ニコチンを含む、前記〔１〕～〔７〕のいずれか一項に記載のニコチンパウチ組成物。
〔９〕
前記ニコチンがニコチン塩を含む、前記〔１〕～〔８〕のいずれか一項に記載のニコチンパウチ組成物。
〔１０〕
前記ニコチンがイオン交換樹脂に結合したニコチンを含む、前記〔１〕～〔９〕のいずれか一項に記載のニコチンパウチ組成物。
〔１１〕
前記ニコチンが合成ニコチンを含む、前記〔１〕～〔１０〕のいずれか一項に記載のニコチンパウチ組成物。
〔１２〕
前記パウチ組成物は、同パウチ組成物の少なくとも０．１重量％、例えば少なくとも０．２重量％などの量でニコチンを含む、前記〔１〕～〔１１〕のいずれか一項に記載のニコチンパウチ組成物。
〔１３〕
前記パウチ組成物は、前記パウチ組成物の０．１～５．０重量％、例えば前記パウチ組成物の０．２～４．０重量％など、例えば前記パウチ組成物の１．０～２．０重量％などの量でニコチンを含む、前記〔１〕～〔１２〕のいずれか一項に記載のニコチンパウチ組成物。
〔１４〕
前記パウチ組成物は、パウチで提供され、実施例３Ｋに記載されたように放出を測定した場合、口腔内の唾液と接触して１２０秒の期間内に少なくとも１５重量％のニコチン、例えば少なくとも２０重量％などのニコチン、例えば少なくとも３０重量％などのニコチン、例えば少なくとも４０重量％などのニコチンを放出するように適合されている、前記〔１〕～〔１３〕のいずれか一項に記載のニコチンパウチ組成物。
〔１５〕
パウチで前記口腔に提供される前記パウチ組成物は、２分から１０分までの放出期間内に１分間あたり少なくとも０．２％、例えば２分から１０分までの放出期間内に１分間あたり少なくとも０．３％など、例えば２分から１０分までの放出期間内に１分間あたり少なくとも０．４％など、例えば２分から１０分までの放出期間内に１分間あたり少なくとも０．５％などのニコチンの放出率を有する、前記〔１〕～〔１４〕のいずれか一項に記載のニコチンパウチ組成物。
〔１６〕
前記パウチが塩基性緩衝剤などの塩基性ｐＨ制御剤などのｐＨ制御剤をさらに含む、前記〔１〕～〔１５〕のいずれか一項に記載のニコチンパウチ組成物。
〔１７〕
前記パウチ組成物がアルカリ性緩衝剤を含む、前記〔１〕～〔１６〕のいずれか一項に記載のニコチンパウチ組成物。
〔１８〕
前記パウチ組成物は、前記パウチ組成物の０．０１～１５重量％、例えば前記パウチ組成物の０．５～１０重量％など、例えば前記パウチ組成物の１～１０重量％など、例えば前記パウチ組成物の５～１０重量％などの量でｐＨ制御剤を含む、前記〔１〕～〔１７〕のいずれか一項に記載のニコチンパウチ組成物。
〔１９〕
前記パウチ組成物は、前記ｐＨ制御剤を、前記パウチ組成物の５重量％未満、例えば前記パウチ組成物の４重量％未満など、例えば前記パウチ組成物の２重量％未満など、例えば前記パウチ組成物の１重量％未満など、例えばｐＨ制御剤を含まない、といった量で含む、前記〔１〕～〔１８〕のいずれか一項に記載のニコチンパウチ組成物。
〔２０〕
前記パウチ組成物は、２．０グラムのパウチ組成物を２０ｍＬの０．０２Ｍリン酸二水素カリウム緩衝液（ｐＨ７．４）に添加したときに、少なくとも８．０のｐＨ、例えば少なくとも９．０などのｐＨを与えるように適合されている、前記〔１〕～〔１９〕のいずれか一項に記載のニコチンパウチ組成物。
〔２１〕
前記ｐＨ制御剤は、酢酸、アジピン酸、クエン酸、フマル酸、グルコノ－δ－ラクトン、グルコン酸、乳酸、リンゴ酸、マレイン酸、酒石酸、コハク酸、プロピオン酸、アスコルビン酸、リン酸、オルトリン酸ナトリウム、オルトリン酸カリウム、オルトリン酸カルシウム、二リン酸ナトリウム、二リン酸カリウム、二リン酸カルシウム、三リン酸五ナトリウム、三リン酸五カリウム、ポリリン酸ナトリウム、ポリリン酸カリウム、炭酸、炭酸ナトリウム、炭酸水素ナトリウム、炭酸カリウム、炭酸カルシウム、炭酸マグネシウム、酸化マグネシウム、またはこれらの任意の組み合わせ、からなる群より選択される、前記〔１〕～〔２０〕のいずれか一項に記載のニコチンパウチ組成物。
〔２２〕
前記ｐＨ制御剤は、塩基性緩衝剤などの塩基性ｐＨ制御剤、および／または、炭酸ナトリウム、炭酸水素ナトリウム、炭酸カリウム、炭酸水素カリウム、炭酸マグネシウム、またはそれらの任意の組み合わせなどである、前記〔１〕～〔２１〕のいずれか一項に記載のニコチンパウチ組成物。
〔２３〕
前記少なくとも１つの糖アルコールは、キシリトール、マルチトール、マンニトール、エリスリトール、イソマルト、ソルビトール、ラクチトール、およびそれらの混合物から選択される、前記〔１〕～〔２２〕のいずれか一項に記載のニコチンパウチ組成物。
〔２４〕
前記少なくとも１つの糖アルコールは、キシリトール、マルチトール、マンニトール、エリスリトール、イソマルト、ラクチトール、およびそれらの混合物から選択される、前記〔１〕～〔２３〕のいずれか一項に記載のニコチンパウチ組成物。
〔２５〕
前記パウチ組成物が少なくとも２つの糖アルコールを含む、前記〔１〕～〔２４〕のいずれか一項に記載のニコチンパウチ組成物。
〔２６〕
前記パウチ組成物は、前記組成物の少なくとも１重量％、例えば前記組成物の少なくとも２重量％など、例えば前記組成物の少なくとも５重量％など、例えば前記組成物の少なくとも１０重量％などの量で糖アルコールを含む、前記〔１〕～〔２５〕のいずれか一項に記載のニコチンパウチ組成物。
〔２７〕
前記パウチ組成物は、前記組成物の１～８０重量％、例えば前記組成物の２～７０重量％など、例えば前記組成物の５～６０重量％など、例えば前記組成物の１０～５０重量％などの量で糖アルコールを含む、前記〔１〕～〔２６〕のいずれか一項に記載のニコチンパウチ組成物。
〔２８〕
前記糖アルコールがＤＣ（直接圧縮性）グレードの糖アルコールを含む、前記〔１〕～〔２７〕のいずれか一項に記載のニコチンパウチ組成物。
〔２９〕
前記糖アルコールの少なくとも５０重量％がＤＣ（直接圧縮性）グレードの糖アルコールである、前記〔１〕～〔２８〕のいずれか一項に記載のニコチンパウチ組成物。
〔３０〕
前記水不溶性繊維が植物繊維である、前記〔１〕～〔２９〕のいずれか一項に記載のニコチンパウチ組成物。
〔３１〕
前記水不溶性繊維は、コムギ繊維、エンドウマメ繊維、コメ繊維、メイズ繊維、オートムギ繊維、トマト繊維、オオムギ繊維、ライムギ繊維、サトウダイコン繊維、ソバ繊維、ジャガイモ繊維、セルロース繊維、リンゴ繊維、カカオ繊維、セルロース繊維、ふすま繊維、竹繊維、粉末セルロース、およびこれらの組み合わせから選択される、前記〔１〕～〔３０〕のいずれか一項に記載のニコチンパウチ組成物。
〔３２〕
前記水不溶性組成物が、コムギ繊維、オートムギ繊維、エンドウマメ繊維、粉末セルロース、またはそれらの組み合わせから選択される水不溶性繊維を含むか、またはそれからなる、前記〔１〕～〔３１〕のいずれか一項に記載のニコチンパウチ組成物。
〔３３〕
前記水不溶性繊維が、少なくとも２００％、例えば、少なくとも３００％など、例えば少なくとも４００％などの水結合能を有する、前記〔１〕～〔３２〕のいずれか一項に記載のニコチンパウチ組成物。
〔３４〕
前記水不溶性繊維が、５．０～２０ｍＬ／ｇなど、少なくとも５．０ｍＬ／ｇの膨潤能を有する、前記〔１〕～〔３３〕のいずれか一項に記載のニコチンパウチ組成物。
〔３５〕
前記水不溶性組成物が、前記パウチ組成物の５～５０重量％の水不溶性繊維、および前記パウチ組成物の１５～７０重量％の含水量、を含むか、またはそれからなる、前記〔１〕～〔３４〕のいずれか一項に記載のニコチンパウチ組成物。
〔３６〕
前記水不溶性組成物が、エンドウマメ繊維、粉末セルロース、およびそれらの組み合わせから選択され、前記パウチ組成物が前記パウチ組成物の１０重量％以下の量で香味料を含む、前記〔１〕～〔３５〕のいずれか一項に記載のニコチンパウチ組成物。
〔３７〕
前記水不溶性組成物が、１リットルあたり５０～５００グラム、例えば１リットルあたり１００～４００グラムなど、例えば１リットルあたり２００～３００グラムなどの密度を有する、前記〔１〕～〔３６〕のいずれか一項に記載のニコチンパウチ組成物。
〔３８〕
前記パウチ組成物が少なくとも４５度、例えば少なくとも５０度などの安息角を有する、前記〔１〕～〔３７〕のいずれか一項に記載のニコチンパウチ組成物。
〔３９〕
前記パウチ組成物は、前記組成物の１０～６０重量％、例えば前記組成物の１０～５０重量％など、例えば前記組成物の１０～４０重量％など、例えば前記組成物の２０～４０重量％などの量で水を含む、前記〔１〕～〔３８〕のいずれか一項に記載のニコチンパウチ組成物。
〔４０〕
前記パウチ組成物が前記組成物の１０～４０重量％の量で水を含む、前記〔１〕～〔３９〕のいずれか一項に記載のニコチンパウチ組成物。
〔４１〕
前記パウチ組成物は、前記組成物の２０～６５重量％、例えば前記組成物の２０～６０重量％など、例えば前記組成物の２０～５０重量％など、例えば前記組成物の２０～４０重量％などの量で水を含む、前記〔１〕～〔４０〕のいずれか一項に記載のニコチンパウチ組成物。
〔４２〕
前記パウチ組成物は、前記パウチ組成物の１５～６５重量％、例えば前記パウチ組成物の１５～５０重量％など、例えば前記パウチ組成物の１５～４０重量％など、例えば前記パウチ組成物の１５～３０重量％など、例えば前記パウチ組成物の１５～２５重量％などの含水量を有する、前記〔１〕～〔４１〕のいずれか一項に記載のニコチンパウチ組成物。
〔４３〕
前記パウチ組成物が、３．０以下、例えば２．５以下など、例えば２．０以下など、例えば１．５以下など、例えば１．０以下などの重量比の水および水不溶性繊維を含む、前記〔１〕～〔４２〕のいずれか一項に記載のニコチンパウチ組成物。
〔４４〕
前記パウチ組成物がタバコ、タバコ繊維、タバコ由来の繊維を含んでいない、前記〔１〕～〔４３〕のいずれか一項に記載のニコチンパウチ組成物。
〔４５〕
前記パウチ組成物が保水剤をさらに含む、前記〔１〕～〔４４〕のいずれか一項に記載のニコチンパウチ組成物。
〔４６〕
前記パウチ組成物は、二酸化ケイ素などの流動促進剤を、例えば前記組成物の０．５～５重量％、例えば前記組成物の１～３重量％などの量で含む、前記〔１〕～〔４５〕のいずれか一項に記載のニコチンパウチ組成物。
〔４７〕
前記パウチ組成物は香味料を含み、例えば前記パウチ組成物の０．０１～２０重量％の量、例えば前記パウチ組成物の０．０１～１５重量％などの量で含む、前記〔１〕～〔４６〕のいずれか一項に記載のニコチンパウチ組成物。
〔４８〕
前記パウチ組成物を含む一連の少なくとも１０個の経口パウチ間のニコチンの含量は、１０％以下、好ましくは８％以下、より好ましくは最大６％、さらに好ましくは最大４％、最も好ましくは最大２％の相対標準偏差（ＲＳＤ）を保持する、前記〔１〕～〔４７〕のいずれか一項に記載のニコチンパウチ組成物。
〔４９〕
前記組成物は、ソルビトール、エリスリトール、キシリトール、ラクチトール、マルチトール、マンニトール、加水分解水添デンプン、イソマルト、またはそれらの任意の組み合わせからなる群から選択される糖アルコールを含み、前記組成物は、前記パウチ組成物の１～８０重量％、例えば前記パウチ組成物の５～７０重量％など、例えば前記パウチ組成物の１０～６０重量％などの量で前記糖アルコールを含む、前記〔１〕～〔４８〕のいずれか一項に記載のニコチンパウチ組成物。
〔５０〕
前記パウチ組成物は、ソルビトール、エリスリトール、キシリトール、ラクチトール、マルチトール、マンニトール、加水分解水添デンプン、イソマルト、またはそれらの任意の組み合わせからなる群から選択される糖アルコールを含み、
前記組成物は、前記パウチ組成物の１～８０重量％、例えば前記パウチ組成物の５～７０重量％など、例えば前記パウチ組成物の１０～６０重量％などの量で前記糖アルコールを含み、かつ
前記組成物は、前記パウチ組成物の５～５０重量％、例えば前記パウチ組成物の１０～３０重量％などの量で水不溶性繊維をさらに含む、前記〔１〕～〔４９〕のいずれか一項に記載のニコチンパウチ組成物。
〔５１〕
前記パウチ組成物は、ソルビトール、エリスリトール、キシリトール、ラクチトール、マルチトール、マンニトール、加水分解水添デンプン、イソマルト、またはそれらの任意の組み合わせからなる群から選択される糖アルコールを含み、
前記組成物は、前記パウチ組成物の１～８０重量％、例えば前記パウチ組成物の５～７０重量％など、例えば前記パウチ組成物の１０～６０重量％などの量で前記糖アルコールを含み、
前記組成物は、前記パウチ組成物の５～５０重量％、例えば前記パウチ組成物の１０～３０重量％などの量で水不溶性繊維をさらに含み、かつ
前記水不溶性組成物が、コムギ繊維、オートムギ繊維、エンドウマメ繊維、粉末セルロース、またはそれらの組み合わせなどの水不溶性繊維を含むか、またはそれからなる、前記〔１〕～〔５０〕のいずれか一項に記載のニコチンパウチ組成物。
〔５２〕
前記パウチ組成物は、ソルビトール、エリスリトール、キシリトール、ラクチトール、マルチトール、マンニトール、加水分解水添デンプン、イソマルト、またはそれらの任意の組み合わせからなる群から選択される糖アルコールを含み、
前記組成物は、前記パウチ組成物の１～８０重量％、例えば前記パウチ組成物の５～７０重量％など、例えば前記パウチ組成物の１０～６０重量％などの量で前記糖アルコールを含み、
前記組成物は、前記パウチ組成物の５～５０重量％、例えば前記パウチ組成物の１０～３０重量％などの量で水不溶性繊維をさらに含み、かつ
前記水不溶性組成物が、コムギ繊維、オートムギ繊維、エンドウマメ繊維、粉末セルロース、またはそれらの組み合わせなどの水不溶性繊維を含むか、またはそれらからなり、前記パウチ組成物は、前記パウチ組成物の０．０１～１５重量％、例えばパウチ組成物の０．１～１５重量％など、例えばパウチ組成物の１～１０重量％など、例えばパウチ組成物の３～１０重量％などの量で香味料を含む、前記〔１〕～〔５１〕のいずれか一項に記載のニコチンパウチ組成物。
〔５３〕
前記パウチ組成物は、ソルビトール、エリスリトール、キシリトール、ラクチトール、マルチトール、マンニトール、加水分解水添デンプン、イソマルト、またはそれらの任意の組み合わせからなる群から選択される糖アルコールを含み、
前記組成物は、前記パウチ組成物の１～８０重量％、例えば前記パウチ組成物の５～７０重量％など、例えば前記パウチ組成物の１０～６０重量％などの量で前記糖アルコールを含み、
組成物は、前記パウチ組成物の５～５０重量％、例えば前記パウチ組成物の１０～３０重量％などの量で水不溶性繊維をさらに含み、
前記水不溶性組成物は、水不溶性繊維、例えば、コムギ繊維、オートムギ繊維、エンドウマメ繊維、粉末セルロース、またはそれらの組み合わせを含むか、またはそれらからなるものであり、前記パウチ組成物は、前記パウチ組成物の０．０１～１５重量％、例えば前記パウチ組成物の０．１～１５重量％など、例えば前記パウチ組成物の１～１０重量％など、例えば前記パウチ組成物の３～１０重量％などの量で香味料を含み、かつ同香味料は油系である、前記〔１〕～〔５２〕のいずれか一項に記載のニコチンパウチ組成物。
〔５４〕
前記パウチ組成物は、ソルビトール、エリスリトール、キシリトール、ラクチトール、マルチトール、マンニトール、加水分解水添デンプン、イソマルト、またはそれらの任意の組み合わせからなる群から選択される糖アルコールを含み、
前記組成物は、前記パウチ組成物の１～８０重量％、例えば前記パウチ組成物の５～７０重量％など、例えば前記パウチ組成物の１０～６０重量％などの量で前記糖アルコールを含み、
前記組成物は、前記パウチ組成物の５～５０重量％、例えば前記パウチ組成物の１０～３０重量％などの量で水不溶性繊維をさらに含み、
前記パウチ組成物は、酢酸、アジピン酸、クエン酸、フマル酸、グルコノ－δ－ラクトン、グルコン酸、乳酸、リンゴ酸、マレイン酸、酒石酸、コハク酸、プロピオン酸、アスコルビン酸、リン酸、オルトリン酸ナトリウム、オルトリン酸カリウム、オルトリン酸カルシウム、二リン酸ナトリウム、二リン酸カリウム、二リン酸カルシウム、三リン酸五ナトリウム、三リン酸五カリウム、ポリリン酸ナトリウム、ポリリン酸カリウム、炭酸、炭酸ナトリウム、炭酸水素ナトリウム、炭酸カリウム、炭酸カルシウム、炭酸マグネシウム、酸化マグネシウム、またはこれらの任意の組み合わせ、からなる群より選択されるｐＨ制御剤を含む、前記〔１〕～〔５３〕のいずれか一項に記載のニコチンパウチ組成物。
〔５５〕
前記パウチ組成物は、ソルビトール、エリスリトール、キシリトール、ラクチトール、マルチトール、マンニトール、加水分解水添デンプン、イソマルト、またはそれらの任意の組み合わせからなる群から選択される糖アルコールを含み、
前記組成物は、前記パウチ組成物の１～８０重量％、例えば前記パウチ組成物の５～７０重量％など、例えば前記パウチ組成物の１０～６０重量％などの量で前記糖アルコールを含み、
前記組成物は、前記パウチ組成物の５～５０重量％、例えば前記パウチ組成物の１０～３０重量％などの量で水不溶性繊維をさらに含み、かつ
前記パウチ組成物が、塩基性緩衝剤などの塩基性ｐＨ制御剤、および／または、炭酸ナトリウム、炭酸水素ナトリウム、炭酸カリウム、炭酸水素カリウム、炭酸マグネシウム、またはそれらの任意の組み合わせであるｐＨ制御剤を含む、前記〔１〕～〔５４〕のいずれか一項に記載のニコチンパウチ組成物。
〔５６〕
経口パウチ詰めニコチン製品であって、
唾液透過性（ｓａｌｉｖａ－ｐｅｒｍｅａｂｌｅ）パウチと、
ニコチンパウチ組成物と、
を含み、前記ニコチンパウチ組成物は：
少なくとも１つの糖アルコールと、
少なくとも１つの水不溶性繊維と、
前記組成物の８～６５重量％の量の水と、
ニコチンと、
を含み、
前記パウチは最大内側パウチ体積を有し、前記ニコチンパウチ組成物は、前記最大内側パウチ体積の少なくとも６５％に対応する体積を有する、経口パウチ詰めニコチン製品。
〔５７〕
前記組成物は、前記パウチ内で０．８ｇ／ｃｍ３未満、例えば０．７ｇ／ｃｍ３未満など、例えば０．６ｇ／ｃｍ３未満など、例えば０．５ｇ／ｃｍ３未満などのかさ密度を有する、前記〔５６〕に記載の経口パウチ詰めニコチン製品。
〔５８〕
前記パウチは最大内側パウチ体積を有し、前記ニコチンパウチ組成物は、前記最大内側パウチ体積の少なくとも７０％、例えば前記最大内側パウチ体積の少なくとも８０％など、例えば前記最大内側パウチ体積による少なくとも９０％など、例えば前記最大内側パウチ体積による少なくとも９５％など、に対応する体積を有する、前記〔５６〕または前記〔５７〕に記載の経口パウチ詰めニコチン製品。
〔５９〕
前記最大内側パウチ体積は、少なくとも０．５ｍＬ、例えば少なくとも１．０ｍＬなどである、前記〔５６〕～〔５８〕のいずれか一項に記載の経口パウチ詰めニコチン製品。
〔６０〕
前記パウチの前記膜は、前記パウチ詰め製品に含まれる水不溶性繊維とは異なる起源の水不溶性繊維を含む、前記〔５６〕～〔５９〕のいずれか一項に記載の経口パウチ詰めニコチン製品。
〔６１〕
前記膜の前記水不溶性繊維および前記パウチ組成物の前記水不溶性繊維の両方が天然繊維を含む、前記〔５６〕～〔６０〕のいずれか一項に記載の経口パウチ詰めニコチン製品。
〔６２〕
前記膜の前記水不溶性繊維および前記パウチ組成物の前記水不溶性繊維の両方が天然繊維である、前記〔５６〕～〔６１〕のいずれか一項に記載の経口パウチ詰めニコチン製品。
〔６３〕
前記〔１〕～〔５５〕のいずれかに記載のニコチンパウチ組成物を含む、前記〔５６〕～〔６２〕のいずれか一項に記載の経口ニコチンパウチ詰め製品。
〔６４〕
前記〔５６〕～〔６３〕のいずれか一項に記載の経口パウチ詰め製品を製造する方法であって、添加するステップを含む前記方法は：
－前記〔１〕～〔５５〕のいずれか一項に記載のパウチ組成物を提供することと、
－前記唾液透過性パウチを提供することと、
－前記パウチ組成物を前記パウチに添加することと、
－前記パウチを密封することと、
を含む、方法。
The addition of 10% NaCl also appears to improve the release obtained after 10 minutes (PPC94).
Another aspect of the present invention may be as follows.
[1]
A nicotine pouch composition comprising:
at least one sugar alcohol;
at least one water-insoluble fiber;
water in an amount of 8 to 65% by weight of the composition;
nicotine and
A nicotine pouch composition comprising:
[2]
Said composition has a bulk density of at most 0.8 g/cm3, such as at most 0.7 g/cm3, such as at most 0.6 g/cm3, such as at most 0.5 g/cm3, said [ 1], the nicotine pouch composition according to the above.
[3]
The composition may range from 0.2 g/cm3 to 0.8 g/cm3, such as from 0.3 g/cm3 to 0.7 g/cm3, such as from 0.3 g/cm3 to 0.6 g/cm3, such as from 0.4 g/cm3 to The nicotine pouch composition according to [1] or [2] above, which has a bulk density of 0.5 g/cm3 or the like.
[4]
Said nicotine may be nicotine salts, nicotine free base, nicotine bound to ion exchangers such as nicotine polacrilex resins, nicotine inclusion complexes or any non-covalently bound nicotine, nicotine bound to zeolite , nicotine bound to cellulose such as microcrystalline cellulose, or starch microspheres, and mixtures thereof.
[5]
The nicotine pouch composition according to any one of [1] to [4] above, wherein the nicotine comprises non-salt nicotine.
[6]
The nicotine pouch composition according to any one of [1] to [5] above, wherein the nicotine comprises a nicotine free base.
[7]
The nicotine pouch composition according to any one of [1] to [6] above, wherein the nicotine contains nicotine mixed with an ion exchange resin.
[8]
Said nicotine is ionically The nicotine pouch composition according to any one of [1] to [7] above, which contains free base nicotine mixed with an exchange resin.
[9]
The nicotine pouch composition according to any one of [1] to [8] above, wherein the nicotine comprises a nicotine salt.
[10]
The nicotine pouch composition according to any one of [1] to [9] above, wherein the nicotine comprises nicotine bound to an ion exchange resin.
[11]
The nicotine pouch composition according to any one of [1] to [10] above, wherein the nicotine comprises synthetic nicotine.
[12]
The nicotine according to any one of [1] to [11] above, wherein the pouch composition contains nicotine in an amount of at least 0.1% by weight, such as at least 0.2% by weight of the pouch composition. pouch composition.
[13]
The pouch composition may comprise 0.1 to 5.0% by weight of the pouch composition, such as 0.2 to 4.0% by weight of the pouch composition, such as 1.0 to 2.0% by weight of the pouch composition. The nicotine pouch composition according to any one of [1] to [12] above, which contains nicotine in an amount such as 0% by weight.
[14]
Said pouch composition comprises at least 15% by weight nicotine, e.g. Nicotine according to any one of the above [1] to [13], adapted to release nicotine such as wt%, such as at least 30 wt% nicotine, such as at least 40 wt% nicotine pouch composition.
[15]
Said pouch composition provided to said oral cavity in a pouch contains at least 0.2% per minute within a release period of 2 to 10 minutes, such as at least 0.2% per minute within a release period of 2 to 10 minutes. A release rate of nicotine such as 3%, such as at least 0.4% per minute within a release period of 2 to 10 minutes, such as at least 0.5% per minute within a release period of 2 to 10 minutes The nicotine pouch composition according to any one of [1] to [14] above.
[16]
The nicotine pouch composition according to any one of [1] to [15] above, wherein the pouch further contains a pH control agent such as a basic pH control agent such as a basic buffer.
[17]
The nicotine pouch composition according to any one of [1] to [16] above, wherein the pouch composition contains an alkaline buffer.
[18]
The pouch composition comprises 0.01 to 15% by weight of the pouch composition, such as 0.5 to 10% by weight of the pouch composition, such as 1 to 10% by weight of the pouch composition, such as the pouch composition. The nicotine pouch composition according to any one of [1] to [17] above, which contains a pH control agent in an amount such as 5 to 10% by weight of the composition.
[19]
The pouch composition comprises less than 5% by weight of the pouch composition, such as less than 4% by weight of the pouch composition, such as less than 2% by weight of the pouch composition, such as less than 2% by weight of the pouch composition, such as The nicotine pouch composition according to any one of the above [1] to [18], which contains less than 1% by weight of the product, for example, does not contain a pH control agent.
[20]
The pouch composition has a pH of at least 8.0, such as at least 9.0 when 2.0 grams of the pouch composition is added to 20 mL of 0.02 M potassium dihydrogen phosphate buffer (pH 7.4) The nicotine pouch composition according to any one of the above [1] to [19], which is adapted to give a pH such as
[21]
The pH control agent includes acetic acid, adipic acid, citric acid, fumaric acid, glucono-δ-lactone, gluconic acid, lactic acid, malic acid, maleic acid, tartaric acid, succinic acid, propionic acid, ascorbic acid, phosphoric acid, and orthophosphoric acid. sodium, potassium orthophosphate, calcium orthophosphate, sodium diphosphate, potassium diphosphate, calcium diphosphate, pentasodium triphosphate, pentapotassium triphosphate, sodium polyphosphate, potassium polyphosphate, carbonic acid, sodium carbonate, sodium bicarbonate , potassium carbonate, calcium carbonate, magnesium carbonate, magnesium oxide, or any combination thereof.
[22]
The pH control agent is a basic pH control agent, such as a basic buffer, and/or sodium carbonate, sodium bicarbonate, potassium carbonate, potassium bicarbonate, magnesium carbonate, or any combination thereof. [1] The nicotine pouch composition according to any one of [21].
[23]
The nicotine pouch according to any one of [1] to [22] above, wherein the at least one sugar alcohol is selected from xylitol, maltitol, mannitol, erythritol, isomalt, sorbitol, lactitol, and mixtures thereof. Composition.
[24]
The nicotine pouch composition according to any one of [1] to [23] above, wherein the at least one sugar alcohol is selected from xylitol, maltitol, mannitol, erythritol, isomalt, lactitol, and mixtures thereof. .
[25]
The nicotine pouch composition according to any one of [1] to [24] above, wherein the pouch composition contains at least two sugar alcohols.
[26]
The pouch composition in an amount of at least 1% by weight of the composition, such as at least 2% by weight of the composition, such as at least 5% by weight of the composition, such as at least 10% by weight of the composition The nicotine pouch composition according to any one of [1] to [25] above, which contains a sugar alcohol.
[27]
The pouch composition comprises 1-80% by weight of the composition, such as 2-70% by weight of the composition, such as 5-60% by weight of the composition, such as 10-50% by weight of the composition. The nicotine pouch composition according to any one of [1] to [26] above, which contains a sugar alcohol in an amount such as
[28]
The nicotine pouch composition according to any one of [1] to [27] above, wherein the sugar alcohol comprises a DC (directly compressible) grade sugar alcohol.
[29]
The nicotine pouch composition according to any one of [1] to [28] above, wherein at least 50% by weight of the sugar alcohol is a DC (direct compressible) grade sugar alcohol.
[30]
The nicotine pouch composition according to any one of [1] to [29] above, wherein the water-insoluble fiber is vegetable fiber.
[31]
The water-insoluble fibers include wheat fiber, pea fiber, rice fiber, maize fiber, oat fiber, tomato fiber, barley fiber, rye fiber, sugar beet fiber, buckwheat fiber, potato fiber, cellulose fiber, apple fiber, cocoa fiber, The nicotine pouch composition according to any one of [1] to [30] above, which is selected from cellulose fibers, bran fibers, bamboo fibers, powdered cellulose, and combinations thereof.
[32]
Any of the above [1] to [31], wherein the water-insoluble composition comprises or consists of water-insoluble fibers selected from wheat fiber, oat fiber, pea fiber, powdered cellulose, or combinations thereof. A nicotine pouch composition according to claim 1.
[33]
The nicotine pouch composition according to any one of [1] to [32] above, wherein the water-insoluble fiber has a water binding capacity of at least 200%, such as at least 300%, such as at least 400%.
[34]
The nicotine pouch composition according to any one of [1] to [33] above, wherein the water-insoluble fiber has a swelling capacity of at least 5.0 mL/g, such as 5.0 to 20 mL/g.
[35]
The water-insoluble composition comprises or consists of water-insoluble fibers of 5 to 50% by weight of the pouch composition and water content of 15 to 70% by weight of the pouch composition, [1] to The nicotine pouch composition according to any one of [34].
[36]
[1] to [ 35], the nicotine pouch composition according to any one of the above items.
[37]
Any of the above [1] to [36], wherein the water-insoluble composition has a density of 50 to 500 grams per liter, such as 100 to 400 grams per liter, such as 200 to 300 grams per liter. A nicotine pouch composition according to claim 1.
[38]
The nicotine pouch composition according to any one of [1] to [37] above, wherein the pouch composition has an angle of repose of at least 45 degrees, such as at least 50 degrees.
[39]
The pouch composition comprises 10-60% by weight of the composition, such as 10-50% by weight of the composition, such as 10-40% by weight of the composition, such as 20-40% by weight of the composition. The nicotine pouch composition according to any one of the above [1] to [38], which contains water in an amount such as
[40]
The nicotine pouch composition according to any one of [1] to [39] above, wherein the pouch composition contains water in an amount of 10 to 40% by weight of the composition.
[41]
The pouch composition comprises 20-65% by weight of the composition, such as 20-60% by weight of the composition, such as 20-50% by weight of the composition, such as 20-40% by weight of the composition. The nicotine pouch composition according to any one of [1] to [40] above, which contains water in an amount such as
[42]
The pouch composition comprises 15-65% by weight of the pouch composition, such as 15-50% by weight of the pouch composition, such as 15-40% by weight of the pouch composition, such as 15% by weight of the pouch composition. The nicotine pouch composition according to any one of the above [1] to [41], having a water content such as -30% by weight, such as 15-25% by weight of the pouch composition.
[43]
wherein the pouch composition comprises water and water-insoluble fibers in a weight ratio of 3.0 or less, such as 2.5 or less, such as 2.0 or less, such as 1.5 or less, such as 1.0 or less; The nicotine pouch composition according to any one of [1] to [42].
[44]
The nicotine pouch composition according to any one of [1] to [43], wherein the pouch composition does not contain tobacco, tobacco fiber, or tobacco-derived fiber.
[45]
The nicotine pouch composition according to any one of [1] to [44], wherein the pouch composition further contains a water retention agent.
[46]
The pouch composition contains a glidant such as silicon dioxide in an amount of, for example, 0.5 to 5% by weight of the composition, such as 1 to 3% by weight of the composition, [1] to [ 45], the nicotine pouch composition according to any one of items.
[47]
The pouch composition contains a flavoring agent, for example, in an amount of 0.01 to 20% by weight of the pouch composition, for example, in an amount of 0.01 to 15% by weight of the pouch composition, [1] to The nicotine pouch composition according to any one of [46].
[48]
The content of nicotine among a series of at least 10 oral pouches comprising said pouch composition is 10% or less, preferably 8% or less, more preferably up to 6%, even more preferably up to 4%, most preferably up to 2%. % relative standard deviation (RSD), the nicotine pouch composition according to any one of the above [1] to [47].
[49]
Said composition comprises a sugar alcohol selected from the group consisting of sorbitol, erythritol, xylitol, lactitol, maltitol, mannitol, hydrolyzed hydrogenated starch, isomalt, or any combination thereof, said composition comprising said The above [1] to [ 48], the nicotine pouch composition according to any one of items.
[50]
the pouch composition comprises a sugar alcohol selected from the group consisting of sorbitol, erythritol, xylitol, lactitol, maltitol, mannitol, hydrogenated starch hydrolysate, isomalt, or any combination thereof;
The composition comprises the sugar alcohol in an amount of 1-80% by weight of the pouch composition, such as 5-70% by weight of the pouch composition, such as 10-60% by weight of the pouch composition, and
Any one of the above [1] to [49], wherein the composition further contains a water-insoluble fiber in an amount such as 5 to 50% by weight of the pouch composition, such as 10 to 30% by weight of the pouch composition. A nicotine pouch composition according to any one of the preceding paragraphs.
[51]
the pouch composition comprises a sugar alcohol selected from the group consisting of sorbitol, erythritol, xylitol, lactitol, maltitol, mannitol, hydrogenated starch hydrolysate, isomalt, or any combination thereof;
The composition comprises the sugar alcohol in an amount of 1-80% by weight of the pouch composition, such as 5-70% by weight of the pouch composition, such as 10-60% by weight of the pouch composition,
The composition further comprises water-insoluble fibers in an amount of 5-50% by weight of the pouch composition, such as 10-30% by weight of the pouch composition, and
Any one of the above [1] to [50], wherein the water-insoluble composition comprises or consists of water-insoluble fibers such as wheat fiber, oat fiber, pea fiber, powdered cellulose, or combinations thereof. nicotine pouch composition according to .
[52]
the pouch composition comprises a sugar alcohol selected from the group consisting of sorbitol, erythritol, xylitol, lactitol, maltitol, mannitol, hydrogenated starch hydrolysate, isomalt, or any combination thereof;
The composition comprises the sugar alcohol in an amount of 1-80% by weight of the pouch composition, such as 5-70% by weight of the pouch composition, such as 10-60% by weight of the pouch composition,
The composition further comprises water-insoluble fibers in an amount of 5-50% by weight of the pouch composition, such as 10-30% by weight of the pouch composition, and
The water-insoluble composition comprises or consists of water-insoluble fibers such as wheat fiber, oat fiber, pea fiber, powdered cellulose, or combinations thereof, and the pouch composition comprises 0% of the pouch composition. .01-15% by weight of the pouch composition, such as 0.1-15% by weight of the pouch composition, such as 1-10% by weight of the pouch composition, such as 3-10% by weight of the pouch composition. The nicotine pouch composition according to any one of [1] to [51] above.
[53]
the pouch composition comprises a sugar alcohol selected from the group consisting of sorbitol, erythritol, xylitol, lactitol, maltitol, mannitol, hydrogenated starch hydrolysate, isomalt, or any combination thereof;
The composition comprises the sugar alcohol in an amount of 1-80% by weight of the pouch composition, such as 5-70% by weight of the pouch composition, such as 10-60% by weight of the pouch composition,
The composition further comprises water-insoluble fibers in an amount such as 5-50% by weight of said pouch composition, such as 10-30% by weight of said pouch composition;
Said water-insoluble composition comprises or consists of water-insoluble fibers such as wheat fiber, oat fiber, pea fiber, powdered cellulose, or combinations thereof, and said pouch composition comprises said pouch 0.01-15% by weight of the composition, such as 0.1-15% by weight of the pouch composition, such as 1-10% by weight of the pouch composition, such as 3-10% by weight of the pouch composition The nicotine pouch composition according to any one of the above [1] to [52], which contains a flavoring agent in an amount such as , and the flavoring agent is oil-based.
[54]
the pouch composition comprises a sugar alcohol selected from the group consisting of sorbitol, erythritol, xylitol, lactitol, maltitol, mannitol, hydrogenated starch hydrolysate, isomalt, or any combination thereof;
The composition comprises the sugar alcohol in an amount of 1-80% by weight of the pouch composition, such as 5-70% by weight of the pouch composition, such as 10-60% by weight of the pouch composition,
The composition further comprises water-insoluble fibers in an amount of 5-50% by weight of the pouch composition, such as 10-30% by weight of the pouch composition;
The pouch composition contains acetic acid, adipic acid, citric acid, fumaric acid, glucono-δ-lactone, gluconic acid, lactic acid, malic acid, maleic acid, tartaric acid, succinic acid, propionic acid, ascorbic acid, phosphoric acid, and orthophosphoric acid. sodium, potassium orthophosphate, calcium orthophosphate, sodium diphosphate, potassium diphosphate, calcium diphosphate, pentasodium triphosphate, pentapotassium triphosphate, sodium polyphosphate, potassium polyphosphate, carbonic acid, sodium carbonate, sodium bicarbonate , potassium carbonate, calcium carbonate, magnesium carbonate, magnesium oxide, or any combination thereof, containing a pH control agent selected from the group consisting of, nicotine according to any one of the above [1] to [53] pouch composition.
[55]
the pouch composition comprises a sugar alcohol selected from the group consisting of sorbitol, erythritol, xylitol, lactitol, maltitol, mannitol, hydrogenated starch hydrolysate, isomalt, or any combination thereof;
The composition comprises the sugar alcohol in an amount of 1-80% by weight of the pouch composition, such as 5-70% by weight of the pouch composition, such as 10-60% by weight of the pouch composition,
The composition further comprises water-insoluble fibers in an amount of 5-50% by weight of the pouch composition, such as 10-30% by weight of the pouch composition, and
The pouch composition is a basic pH control agent such as a basic buffer and/or a pH control agent that is sodium carbonate, sodium bicarbonate, potassium carbonate, potassium bicarbonate, magnesium carbonate, or any combination thereof. The nicotine pouch composition according to any one of [1] to [54] above, comprising:
[56]
An oral pouched nicotine product comprising:
a saliva-permeable pouch;
a nicotine pouch composition;
wherein the nicotine pouch composition comprises:
at least one sugar alcohol;
at least one water-insoluble fiber;
water in an amount of 8 to 65% by weight of the composition;
nicotine and
including
An oral pouched nicotine product, wherein said pouch has a maximum inner pouch volume and said nicotine pouch composition has a volume corresponding to at least 65% of said maximum inner pouch volume.
[57]
Said composition has a bulk density in said pouch of less than 0.8 g/cm3, such as less than 0.7 g/cm3, such as less than 0.6 g/cm3, such as less than 0.5 g/cm3, said [ 56].
[58]
Said pouch has a maximum inner pouch volume, and said nicotine pouch composition is at least 70% of said maximum inner pouch volume, such as at least 80% of said maximum inner pouch volume, such as at least 90% by said maximum inner pouch volume etc., such as at least 95% by said maximum inner pouch volume.
[59]
The oral pouched nicotine product of any one of paragraphs [56]-[58], wherein said maximum inner pouch volume is at least 0.5 mL, such as at least 1.0 mL.
[60]
The oral pouched nicotine product of any one of paragraphs [56] to [59], wherein the membrane of the pouch comprises water-insoluble fibers of a different origin than the water-insoluble fibers contained in the pouched product.
[61]
The oral pouched nicotine product of any one of paragraphs [56]-[60], wherein both the water-insoluble fibers of the membrane and the water-insoluble fibers of the pouch composition comprise natural fibers.
[62]
[61] The oral pouched nicotine product of any one of [56] to [61], wherein both the water-insoluble fibers of the membrane and the water-insoluble fibers of the pouch composition are natural fibers.
[63]
The oral nicotine pouched product according to any one of [56] to [62], which contains the nicotine pouch composition of any one of [1] to [55].
[64]
A method of manufacturing an oral pouched product according to any one of [56] to [63], said method comprising the step of adding:
- providing the pouch composition according to any one of [1] to [55];
- providing said saliva permeable pouch;
- adding the pouch composition to the pouch;
- sealing the pouch;
A method, including
Claims (23)
少なくとも１つの糖アルコールと、
少なくとも１つの水不溶性繊維と、
前記ニコチンパウチ組成物の８～６５重量％の量の水と、
ニコチンと、
を含むニコチンパウチ組成物。 A nicotine pouch composition comprising:
at least one sugar alcohol;
at least one water-insoluble fiber;
water in an amount of 8-65% by weight of the nicotine pouch composition;
nicotine and
A nicotine pouch composition comprising:
唾液透過性（ｓａｌｉｖａ－ｐｅｒｍｅａｂｌｅ）パウチと、
ニコチンパウチ組成物と、
を含み、前記ニコチンパウチ組成物は：
少なくとも１つの糖アルコールと、
少なくとも１つの水不溶性繊維と、
前記ニコチンパウチ組成物の８～６５重量％の量の水と、
ニコチンと、
を含み、
前記パウチは最大内側パウチ体積を有し、前記ニコチンパウチ組成物は、前記最大内側パウチ体積の少なくとも６５％に対応する体積を有する、経口パウチ詰めニコチン製品。 An oral pouched nicotine product comprising:
a saliva-permeable pouch;
a nicotine pouch composition;
wherein the nicotine pouch composition comprises:
at least one sugar alcohol;
at least one water-insoluble fiber;
water in an amount of 8-65% by weight of the nicotine pouch composition;
nicotine and
including
An oral pouched nicotine product, wherein said pouch has a maximum inner pouch volume and said nicotine pouch composition has a volume corresponding to at least 65% of said maximum inner pouch volume.
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201900698 | 2019-06-07 | ||
| DKPA201900698A DK180339B1 (en) | 2019-06-07 | 2019-06-07 | Nicotine pouch composition and pouch comprising such |
| DKPA201970611 | 2019-09-30 | ||
| DKPA201970610 | 2019-09-30 | ||
| DKPA201970612A DK201970612A1 (en) | 2019-06-07 | 2019-09-30 | Oral pouched product |
| DKPA201970612 | 2019-09-30 | ||
| DKPA201970610A DK180484B1 (en) | 2019-06-07 | 2019-09-30 | Non-tobacco nicotine pouch composition |
| DKPA201970611A DK180614B1 (en) | 2019-06-07 | 2019-09-30 | Pouched product with liquid flavor composition |
| PCT/DK2020/050160 WO2020244722A1 (en) | 2019-06-07 | 2020-06-05 | Nicotine pouch composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022535586A JP2022535586A (en) | 2022-08-09 |
| JPWO2020244722A5 true JPWO2020244722A5 (en) | 2023-06-13 |
Family
ID=73651788
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021572508A Pending JP2022535585A (en) | 2019-06-07 | 2020-06-05 | Pouched product containing liquid flavor composition |
| JP2021572355A Pending JP2022535572A (en) | 2019-06-07 | 2020-06-05 | Nicotine pouch composition and pouch containing same nicotine pouch composition |
| JP2021572413A Pending JP2022536299A (en) | 2019-06-07 | 2020-06-05 | oral pouched products |
| JP2021572509A Pending JP2022535586A (en) | 2019-06-07 | 2020-06-05 | nicotine pouch composition |
| JP2021572510A Pending JP2022535909A (en) | 2019-06-07 | 2020-06-05 | nicotine pouch products |
| JP2022573323A Pending JP2023528025A (en) | 2019-06-07 | 2020-11-16 | Non-tobacco oral nicotine pouch composition |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021572508A Pending JP2022535585A (en) | 2019-06-07 | 2020-06-05 | Pouched product containing liquid flavor composition |
| JP2021572355A Pending JP2022535572A (en) | 2019-06-07 | 2020-06-05 | Nicotine pouch composition and pouch containing same nicotine pouch composition |
| JP2021572413A Pending JP2022536299A (en) | 2019-06-07 | 2020-06-05 | oral pouched products |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021572510A Pending JP2022535909A (en) | 2019-06-07 | 2020-06-05 | nicotine pouch products |
| JP2022573323A Pending JP2023528025A (en) | 2019-06-07 | 2020-11-16 | Non-tobacco oral nicotine pouch composition |
Country Status (15)
| Country | Link |
|---|---|
| US (7) | US11096412B2 (en) |
| EP (9) | EP4079290A1 (en) |
| JP (6) | JP2022535585A (en) |
| KR (5) | KR20220019277A (en) |
| CN (6) | CN113939209A (en) |
| AU (5) | AU2020287470A1 (en) |
| BR (4) | BR112021024686A2 (en) |
| CA (6) | CA3142821A1 (en) |
| DK (7) | DK3826477T3 (en) |
| ES (6) | ES2912935T3 (en) |
| FI (3) | FI3773495T3 (en) |
| MX (5) | MX2021014974A (en) |
| PL (6) | PL3809884T3 (en) |
| WO (6) | WO2020244723A1 (en) |
| ZA (4) | ZA202110039B (en) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160157515A1 (en) | 2014-12-05 | 2016-06-09 | R.J. Reynolds Tobacco Company | Smokeless tobacco pouch |
| DK180339B1 (en) | 2019-06-07 | 2020-12-18 | Ncp Nextgen As | Nicotine pouch composition and pouch comprising such |
| CA3142821A1 (en) * | 2019-06-07 | 2020-12-10 | Ncp Nextgen A/S | Pouched product with liquid flavor composition |
| SE1951054A1 (en) * | 2019-09-18 | 2021-03-19 | Enorama Pharma Ab | Nicotine pouch |
| US11872231B2 (en) | 2019-12-09 | 2024-01-16 | Nicoventures Trading Limited | Moist oral product comprising an active ingredient |
| US11793230B2 (en) | 2019-12-09 | 2023-10-24 | Nicoventures Trading Limited | Oral products with improved binding of active ingredients |
| EP4072516A1 (en) | 2019-12-09 | 2022-10-19 | Nicoventures Trading Limited | Oral product comprising a cannabinoid |
| US11969502B2 (en) | 2019-12-09 | 2024-04-30 | Nicoventures Trading Limited | Oral products |
| US11826462B2 (en) | 2019-12-09 | 2023-11-28 | Nicoventures Trading Limited | Oral product with sustained flavor release |
| US11058142B1 (en) | 2020-10-01 | 2021-07-13 | Tobacco Technology, Inc. | Shisha, heat-not-burn, or combustion casing with active ingredient, product and casing with active ingredient, and method of making the same |
| WO2022072031A1 (en) | 2020-10-01 | 2022-04-07 | Tobacco Technology, Inc. | Shisha, heat-not-burn, or combustion casing, product, and method of making the same |
| US11382861B1 (en) | 2020-12-17 | 2022-07-12 | Nirajkumar Karneshbhai Patel | Nicotine pouch |
| WO2022210841A1 (en) * | 2021-03-30 | 2022-10-06 | 日本たばこ産業株式会社 | Pouch product for use in oral cavity and method for manufacturing same |
| JPWO2022210842A1 (en) * | 2021-03-30 | 2022-10-06 | ||
| US20220312825A1 (en) * | 2021-04-06 | 2022-10-06 | Altria Client Services Llc | Oral pouch product |
| EP4329522A1 (en) * | 2021-04-30 | 2024-03-06 | Nicoventures Trading Limited | Oral products with high-density load |
| KR102616656B1 (en) * | 2021-05-12 | 2023-12-21 | 주식회사 케이티앤지 | Nicotine sheet and aerosol-generating article including the same |
| CZ309558B6 (en) * | 2021-05-25 | 2023-04-12 | Consumer Brands International s.r.o. | The filling of a nicotine preparation, in particular a nicotine bag, and producing it |
| EP4094593A1 (en) * | 2021-05-28 | 2022-11-30 | Swedish Match North Europe AB | A flavoured moist oral pouched nicotine product comprising ethyl cellulose |
| CA3222813A1 (en) * | 2021-06-16 | 2022-12-22 | Anthony Richard Gerardi | Pouched product comprising dissolvable composition |
| CA3238151A1 (en) * | 2021-11-15 | 2023-05-19 | Shahin ROOHINEJAD | Oral products with nicotine-polymer complex |
| US20230240359A1 (en) * | 2022-01-28 | 2023-08-03 | Altria Client Services Llc | Oral pouch product |
| DK181550B1 (en) * | 2022-01-28 | 2024-05-02 | Mac Baren Tobacco Company As | Method for producing a pouch composition |
| WO2023174523A1 (en) | 2022-03-15 | 2023-09-21 | Habit Factory In Sweden Ab | Nicotine composition |
| WO2023210810A1 (en) * | 2022-04-28 | 2023-11-02 | 日本たばこ産業株式会社 | Oral composition |
| WO2023210805A1 (en) * | 2022-04-28 | 2023-11-02 | 日本たばこ産業株式会社 | Oral cavity composition containing organic material |
| KR20230167895A (en) * | 2022-06-03 | 2023-12-12 | 주식회사 케이티앤지 | Smoking article with prevention of nicotine transfer, and aerosol generating system including the same |
| CN115119956B (en) * | 2022-06-23 | 2023-07-14 | 火柴人(深圳)新材料技术有限责任公司 | Sustained-release herbal lip cigarette |
Family Cites Families (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB673587A (en) | 1949-08-23 | 1952-06-11 | Leon Harold Abrahams | Improvements relating to coffee percolator bags |
| US4696315A (en) * | 1985-09-19 | 1987-09-29 | Better Life International, Inc. | Herbal snuff composition |
| US5167244A (en) | 1990-01-19 | 1992-12-01 | Kjerstad Randy E | Tobacco substitute |
| US5204115A (en) | 1990-12-12 | 1993-04-20 | Suomen Xyrofin Oy | Directly compressible xylitol and method |
| US20050061339A1 (en) * | 2001-12-21 | 2005-03-24 | Henri Hansson | Tobacco and/or tobacco substitute composition for use as a snuff in the oral cavity |
| US20050034738A1 (en) | 2003-08-11 | 2005-02-17 | Whalen William F. | Chewing tobacco substitute containing nicotine |
| ES2321721T3 (en) | 2003-09-08 | 2009-06-10 | Mcneil Ab | NICOTINE FORMULATIONS AND USE OF THE SAME. |
| US8323683B2 (en) * | 2005-05-18 | 2012-12-04 | Mcneil-Ppc, Inc. | Flavoring of drug-containing chewing gums |
| US20070062549A1 (en) * | 2005-09-22 | 2007-03-22 | Holton Darrell E Jr | Smokeless tobacco composition |
| WO2007084587A2 (en) | 2006-01-20 | 2007-07-26 | Monosol Rx, Llc | Film lined pouch and method of manufacturing this pouch |
| AU2007224584A1 (en) | 2006-03-16 | 2007-09-20 | Niconovum Ab | Improved snuff composition |
| GB0622252D0 (en) | 2006-11-08 | 2006-12-20 | British American Tobacco Co | Materials and method for agglomeration of tobacco particles |
| US20080302682A1 (en) | 2007-06-11 | 2008-12-11 | Radi Medical Biodegradable Ab | Pouch for tobacco or tobacco substitute |
| US8124147B2 (en) | 2007-07-16 | 2012-02-28 | Philip Morris Usa Inc. | Oral pouch products with immobilized flavorant particles |
| KR101564472B1 (en) * | 2007-10-11 | 2015-10-29 | 필립모리스 프로덕츠 에스.에이. | Smokeless tobacco product |
| WO2010031552A1 (en) | 2008-09-17 | 2010-03-25 | Niconovum Ab | Process for preparing snuff composition |
| US8863755B2 (en) | 2009-02-27 | 2014-10-21 | Philip Morris Usa Inc. | Controlled flavor release tobacco pouch products and methods of making |
| RU2530655C2 (en) * | 2009-04-24 | 2014-10-10 | Омиа Интернэшнл Аг | Meterial in form of particles for controlled release of active ingredients |
| EP2429321A4 (en) * | 2009-05-11 | 2013-03-06 | Us Smokeless Tobacco Co | Method and device for flavoring smokeless tobacco |
| RU2573293C2 (en) | 2010-03-26 | 2016-01-20 | Филип Моррис Продактс С.А. | Inhibition of irritating sensations in process of non-smoking tobacco products consumptions |
| EP2575759B1 (en) | 2010-05-31 | 2016-10-26 | Fertin Pharma A/S | Formulation comprising nicotine and a cation exchange resin |
| WO2011150959A1 (en) | 2010-05-31 | 2011-12-08 | Fertin Pharma A/S | Formulation comprising nicotine and a cation exchange resin |
| SE535587C2 (en) * | 2011-03-29 | 2012-10-02 | Chill Of Sweden Ab | Product containing a free nicotine salt and a non-water-soluble bag |
| US20130078307A1 (en) * | 2011-09-22 | 2013-03-28 | Niconovum Usa, Inc. | Nicotine-containing pharmaceutical composition |
| US10881132B2 (en) | 2011-12-14 | 2021-01-05 | R.J. Reynolds Tobacco Company | Smokeless tobacco product comprising effervescent composition |
| CN102754907B (en) | 2012-01-20 | 2015-06-24 | 奥驰亚客户服务公司 | Oral product |
| SE536491C2 (en) | 2012-03-26 | 2013-12-27 | Bionicotine Ab | Bag containing nicotine and a chewing gum composition |
| EP2649888B1 (en) | 2012-04-10 | 2020-02-19 | Swedish Match North Europe AB | A smokeless tobacco composition comprising non-tobacco fibers and a method for its manufacture |
| GB2504495A (en) | 2012-07-30 | 2014-02-05 | British American Tobacco Co | Fleece for smokeless tobacco pouch |
| US20140255452A1 (en) * | 2013-03-11 | 2014-09-11 | Niconovum Usa, Inc. | Method and apparatus for differentiating oral pouch products |
| EP3021691B1 (en) | 2013-07-19 | 2019-09-04 | Altria Client Services LLC | Methods and systems for incorporating nicotine into oral products |
| US11503853B2 (en) | 2013-09-09 | 2022-11-22 | R.J. Reynolds Tobacco Company | Smokeless tobacco composition incorporating a botanical material |
| US11779045B2 (en) | 2013-10-03 | 2023-10-10 | Altria Client Services Llc | Dissolvable-chewable exhausted-tobacco tablet |
| CN103494324A (en) | 2013-10-08 | 2014-01-08 | 红塔烟草(集团)有限责任公司 | Bagged snus and manufacturing method thereof |
| CA2921650A1 (en) | 2013-10-09 | 2015-04-16 | Swedish Match North Europe Ab | An oral smokeless tobacco composition comprising liberated, delignified tobacco fibres and a method for its manufacture |
| EP3065578B1 (en) * | 2013-11-08 | 2018-12-26 | Swedish Match North Europe AB | Oral smokeless tobacco products and oral smokeless non-tobacco snuff products |
| CA2951601A1 (en) | 2014-06-18 | 2015-12-23 | Swedish Match North Europe Ab | A tobacco or non-tobacco product comprising magnesium carbonate |
| US11019840B2 (en) * | 2014-07-02 | 2021-06-01 | R.J. Reynolds Tobacco Company | Oral pouch products |
| EP3223636B1 (en) | 2014-11-25 | 2020-03-04 | Swedish Match North Europe AB | Oral pouched product |
| US20160157515A1 (en) | 2014-12-05 | 2016-06-09 | R.J. Reynolds Tobacco Company | Smokeless tobacco pouch |
| US9930914B2 (en) | 2014-12-16 | 2018-04-03 | Read Fisher Goode, JR. | Seamless oral pouch product |
| US20160192703A1 (en) | 2015-01-07 | 2016-07-07 | R.J. Reynolds Tobacco Company | Oral pouch products |
| US20180271146A9 (en) | 2015-04-17 | 2018-09-27 | Swedish Match North Europe Ab | Oral pouched product having a rectangular shape |
| JP6945531B2 (en) | 2015-12-02 | 2021-10-06 | スウィーディッシュ・マッチ・ノース・ヨーロップ・アーベー | Methods for Manufacturing Oral Bag Snuff Products |
| GB201603866D0 (en) * | 2016-03-07 | 2016-04-20 | British American Tobacco Co | Smokeless oral tobacco product and preperation thereof |
| US11083211B2 (en) | 2016-04-10 | 2021-08-10 | Resurgent Pharmaceuticals, Inc. | Cannabis based moist snuff |
| FI127620B (en) | 2016-07-12 | 2018-10-31 | Tarmo Pekkarinen | Snuff-type composition of nicotine and crushed linseed |
| WO2018126262A2 (en) | 2016-12-30 | 2018-07-05 | Altria Client Services Llc | Smokeless products containing non-tobacco plant materials |
| JP7157386B2 (en) | 2017-02-09 | 2022-10-20 | コニカミノルタ株式会社 | Scanning optical system for laser radar and laser radar device |
| US20180271139A1 (en) | 2017-03-22 | 2018-09-27 | Swedish Match North Europe Ab | Oral pouched product having a rectangular shape |
| RU2754412C2 (en) * | 2017-04-24 | 2021-09-02 | Свидиш Мэтч Норт Юроп Аб | Flavored wet oral packaged nicotine product containing triglyceride |
| NO343402B1 (en) | 2017-04-24 | 2019-02-25 | Swedish Match North Europe Ab | A flavoured moist oral pouched nicotine product comprising triglyceride and a method for manufacturing thereof. |
| CN107319629A (en) | 2017-06-16 | 2017-11-07 | 云南中烟工业有限责任公司 | A kind of packed buccal cigarette of nicotine complex salt and preparation method thereof |
| US11406630B2 (en) | 2017-06-23 | 2022-08-09 | Ncp Nextgen A/S | Nicotine pouch |
| EP3491940A1 (en) | 2017-11-29 | 2019-06-05 | Reemtsma Cigarettenfabriken GmbH | Method of manufacturing a filling material for a pouched smokeless snus product and filling material manufactured therefrom |
| WO2019110076A1 (en) | 2017-12-08 | 2019-06-13 | Fertin Pharma A/S | High nicotine absorption |
| US11844368B2 (en) | 2017-12-15 | 2023-12-19 | Swedish Match North Europe Ab | Flavoured moist oral pouched nicotine product comprising monoglyceride |
| US11096896B2 (en) | 2018-05-17 | 2021-08-24 | Fertin Pharma A/S | Tablet dosage form for buccal absorption of active ingredients |
| CN109119375A (en) | 2018-07-30 | 2019-01-01 | 惠科股份有限公司 | The detection restorative procedure and photoresist repair apparatus of arraying bread board |
| US10952460B2 (en) * | 2018-11-05 | 2021-03-23 | Blesst Boyz LLC | Composition for a tobacco-free chew and method of manufacturing same |
| JP2022519542A (en) | 2019-02-01 | 2022-03-24 | スウィーディッシュ・マッチ・ノース・ヨーロップ・アーベー | Oral nicotine products containing pH regulators |
| JP7305370B2 (en) | 2019-02-19 | 2023-07-10 | Koa株式会社 | Mounting structure of shunt resistor |
| SE542990C2 (en) | 2019-03-18 | 2020-09-22 | Swedish Match North Europe Ab | A packaging material and an oral pouched nicotine product |
| CA3142821A1 (en) * | 2019-06-07 | 2020-12-10 | Ncp Nextgen A/S | Pouched product with liquid flavor composition |
| US20220272185A1 (en) | 2019-07-08 | 2022-08-25 | Lg Electronics Inc. | Mobile terminal |
| LT3833315T (en) | 2019-10-04 | 2022-12-12 | Evaggelos Schjölin | A pouch product suitable for application in an oral cavity |
| SE2050380A1 (en) | 2020-04-03 | 2021-10-04 | Liw Innovation Ab | New compositions for oral or nasal use |
| NO346000B1 (en) | 2020-09-18 | 2021-12-13 | Swedish Match North Europe Ab | AN ORAL NICOTINE PRODUCT COMPRISING A pH ADJUSTING AGENT |
-
2020
- 2020-06-05 CA CA3142821A patent/CA3142821A1/en active Pending
- 2020-06-05 CN CN202080041491.8A patent/CN113939209A/en active Pending
- 2020-06-05 CN CN202080041482.9A patent/CN113924017A/en active Pending
- 2020-06-05 DK DK20758113.3T patent/DK3826477T3/en active
- 2020-06-05 EP EP22165045.0A patent/EP4079290A1/en active Pending
- 2020-06-05 US US16/894,114 patent/US11096412B2/en active Active
- 2020-06-05 ES ES20732727T patent/ES2912935T3/en active Active
- 2020-06-05 EP EP20732727.1A patent/EP3773494B1/en active Active
- 2020-06-05 CA CA3142800A patent/CA3142800A1/en active Pending
- 2020-06-05 AU AU2020287470A patent/AU2020287470A1/en active Pending
- 2020-06-05 JP JP2021572508A patent/JP2022535585A/en active Pending
- 2020-06-05 DK DK20732727.1T patent/DK3773494T3/en active
- 2020-06-05 US US17/048,058 patent/US11399562B2/en active Active
- 2020-06-05 CA CA3142819A patent/CA3142819A1/en active Pending
- 2020-06-05 JP JP2021572355A patent/JP2022535572A/en active Pending
- 2020-06-05 AU AU2020288679A patent/AU2020288679A1/en active Pending
- 2020-06-05 WO PCT/DK2020/050161 patent/WO2020244723A1/en unknown
- 2020-06-05 WO PCT/DK2020/050163 patent/WO2020244725A1/en unknown
- 2020-06-05 KR KR1020227000688A patent/KR20220019277A/en unknown
- 2020-06-05 DK DK20732729.7T patent/DK3773496T3/en active
- 2020-06-05 KR KR1020227000655A patent/KR20220019274A/en unknown
- 2020-06-05 AU AU2020286907A patent/AU2020286907A1/en active Pending
- 2020-06-05 MX MX2021014974A patent/MX2021014974A/en unknown
- 2020-06-05 WO PCT/DK2020/050159 patent/WO2020244721A1/en unknown
- 2020-06-05 PL PL20758114.1T patent/PL3809884T3/en unknown
- 2020-06-05 EP EP22190973.2A patent/EP4108105A1/en active Pending
- 2020-06-05 DK DK20732728.9T patent/DK3773495T3/en active
- 2020-06-05 WO PCT/DK2020/050160 patent/WO2020244722A1/en unknown
- 2020-06-05 ES ES20732728T patent/ES2935567T3/en active Active
- 2020-06-05 ES ES20758114T patent/ES2929280T3/en active Active
- 2020-06-05 CA CA3142820A patent/CA3142820A1/en active Pending
- 2020-06-05 PL PL20732729T patent/PL3773496T3/en unknown
- 2020-06-05 KR KR1020227000651A patent/KR20220019273A/en unknown
- 2020-06-05 BR BR112021024686A patent/BR112021024686A2/en unknown
- 2020-06-05 WO PCT/DK2020/050162 patent/WO2020244724A1/en unknown
- 2020-06-05 JP JP2021572413A patent/JP2022536299A/en active Pending
- 2020-06-05 BR BR112021024352A patent/BR112021024352A2/en unknown
- 2020-06-05 US US16/894,143 patent/US11540557B2/en active Active
- 2020-06-05 CN CN202080041526.8A patent/CN113966174A/en active Pending
- 2020-06-05 FI FIEP20732728.9T patent/FI3773495T3/en active
- 2020-06-05 JP JP2021572509A patent/JP2022535586A/en active Pending
- 2020-06-05 MX MX2021014976A patent/MX2021014976A/en unknown
- 2020-06-05 MX MX2021014975A patent/MX2021014975A/en unknown
- 2020-06-05 DK DK20758114.1T patent/DK3809884T3/en active
- 2020-06-05 ES ES20732729T patent/ES2906976T3/en active Active
- 2020-06-05 EP EP22208954.2A patent/EP4162927A1/en active Pending
- 2020-06-05 CN CN202080041508.XA patent/CN113939272A/en active Pending
- 2020-06-05 KR KR1020227000686A patent/KR20220019276A/en active Search and Examination
- 2020-06-05 PL PL20732728.9T patent/PL3773495T3/en unknown
- 2020-06-05 EP EP21214053.7A patent/EP3988087A1/en active Pending
- 2020-06-05 US US17/422,684 patent/US11930838B2/en active Active
- 2020-06-05 JP JP2021572510A patent/JP2022535909A/en active Pending
- 2020-06-05 CA CA3142822A patent/CA3142822A1/en active Pending
- 2020-06-05 MX MX2021014977A patent/MX2021014977A/en unknown
- 2020-06-05 BR BR112021024353A patent/BR112021024353A2/en unknown
- 2020-06-05 CN CN202080041486.7A patent/CN113924004B/en active Active
- 2020-06-05 PL PL20732727T patent/PL3773494T3/en unknown
- 2020-06-05 EP EP23202646.8A patent/EP4279072A3/en active Pending
- 2020-06-05 AU AU2020287198A patent/AU2020287198A1/en active Pending
- 2020-06-05 BR BR112021024354A patent/BR112021024354A2/en unknown
- 2020-11-16 EP EP23166789.0A patent/EP4218430A1/en active Pending
- 2020-11-16 DK DK20810868.8T patent/DK3937662T3/en active
- 2020-11-16 PL PL21174121.0T patent/PL3970513T3/en unknown
- 2020-11-16 MX MX2022015179A patent/MX2022015179A/en unknown
- 2020-11-16 PL PL20810868.8T patent/PL3937662T3/en unknown
- 2020-11-16 CN CN202080101388.8A patent/CN115697093A/en active Pending
- 2020-11-16 DK DK21174121.0T patent/DK3970513T3/en active
- 2020-11-16 EP EP20810868.8A patent/EP3937662B1/en active Active
- 2020-11-16 FI FIEP20810868.8T patent/FI3937662T3/en active
- 2020-11-16 WO PCT/DK2020/050311 patent/WO2021244714A1/en active Application Filing
- 2020-11-16 EP EP21174121.0A patent/EP3970513B1/en active Active
- 2020-11-16 CA CA3181464A patent/CA3181464A1/en active Pending
- 2020-11-16 US US18/000,169 patent/US20230210162A1/en active Pending
- 2020-11-16 ES ES21174121T patent/ES2944863T3/en active Active
- 2020-11-16 JP JP2022573323A patent/JP2023528025A/en active Pending
- 2020-11-16 KR KR1020237000034A patent/KR20230021071A/en unknown
- 2020-11-16 AU AU2020452044A patent/AU2020452044A1/en active Pending
- 2020-11-16 ES ES20810868T patent/ES2938076T3/en active Active
- 2020-11-16 FI FIEP21174121.0T patent/FI3970513T3/en active
-
2021
- 2021-07-08 US US17/370,641 patent/US20210329962A1/en active Pending
- 2021-12-06 ZA ZA2021/10039A patent/ZA202110039B/en unknown
- 2021-12-06 ZA ZA2021/10041A patent/ZA202110041B/en unknown
- 2021-12-06 ZA ZA2021/10037A patent/ZA202110037B/en unknown
- 2021-12-06 ZA ZA2021/10040A patent/ZA202110040B/en unknown
-
2022
- 2022-06-23 US US17/847,731 patent/US20220322727A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2020244722A5 (en) | ||
| CN113924004B (en) | Nicotine pouch compositions | |
| JPWO2020244723A5 (en) | ||
| JPWO2020244724A5 (en) | ||
| JPWO2020244725A5 (en) | ||
| JPWO2020244721A5 (en) | ||
| EP3773496B1 (en) | Oral pouched product | |
| CN1957938B (en) | Effervescence tablet of Glucurolactone, and preparation method | |
| RU2021139814A (en) | COMPOSITION OF THE NICOTINE PACK | |
| RU2021139815A (en) | ORAL PRODUCT IN POUCH FORM | |
| JP2011030437A (en) | Tablet confectionery |