JPWO2020205499A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2020205499A5
JPWO2020205499A5 JP2021557383A JP2021557383A JPWO2020205499A5 JP WO2020205499 A5 JPWO2020205499 A5 JP WO2020205499A5 JP 2021557383 A JP2021557383 A JP 2021557383A JP 2021557383 A JP2021557383 A JP 2021557383A JP WO2020205499 A5 JPWO2020205499 A5 JP WO2020205499A5
Authority
JP
Japan
Prior art keywords
seq
amino acid
acid sequence
heavy chain
light chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021557383A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022527084A (ja
JP2022527084A5 (https=
JP7555953B2 (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/025181 external-priority patent/WO2020205499A1/en
Publication of JP2022527084A publication Critical patent/JP2022527084A/ja
Publication of JPWO2020205499A5 publication Critical patent/JPWO2020205499A5/ja
Publication of JP2022527084A5 publication Critical patent/JP2022527084A5/ja
Application granted granted Critical
Publication of JP7555953B2 publication Critical patent/JP7555953B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021557383A 2019-03-29 2020-03-27 Cd38に結合する操作されたバリアント抗体 Active JP7555953B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962825983P 2019-03-29 2019-03-29
US62/825,983 2019-03-29
PCT/US2020/025181 WO2020205499A1 (en) 2019-03-29 2020-03-27 Engineered variant antibodies that bind cd38

Publications (4)

Publication Number Publication Date
JP2022527084A JP2022527084A (ja) 2022-05-30
JPWO2020205499A5 true JPWO2020205499A5 (https=) 2023-02-16
JP2022527084A5 JP2022527084A5 (https=) 2023-02-16
JP7555953B2 JP7555953B2 (ja) 2024-09-25

Family

ID=72666916

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021557383A Active JP7555953B2 (ja) 2019-03-29 2020-03-27 Cd38に結合する操作されたバリアント抗体

Country Status (6)

Country Link
US (1) US20220144966A1 (https=)
EP (1) EP3947465A4 (https=)
JP (1) JP7555953B2 (https=)
CN (2) CN114524877A (https=)
CA (1) CA3134612A1 (https=)
WO (1) WO2020205499A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112313250B (zh) * 2018-06-20 2024-10-01 索伦托药业有限公司 结合cd38的变体抗体
CN114516918B (zh) * 2022-03-04 2022-09-27 四川大学华西医院 一种抗体及其应用
CN114409788B (zh) * 2022-03-04 2022-10-04 四川大学华西医院 抗cd38的抗体及其应用
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof
CN120607617A (zh) * 2024-03-07 2025-09-09 宜明昂科生物医药技术(上海)股份有限公司 靶向cd38和cd47的重组融合蛋白

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7413737B2 (en) * 2003-11-14 2008-08-19 Massachusetts Institute Of Technology Anti-hydroxylase antibodies and uses thereof
EP2567976B1 (en) * 2005-03-23 2017-07-19 Genmab A/S Antibodies against CD38 for treatment of multiple myeloma
US20090258005A1 (en) * 2007-05-29 2009-10-15 Trubion Pharmaceuticals Inc. Therapeutic compositions and methods
JOP20210044A1 (ar) * 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
GB201503812D0 (en) * 2015-03-06 2015-04-22 Univ Aberdeen Antibody molecules and uses thereof
ES2927119T3 (es) * 2015-04-08 2022-11-02 Sorrento Therapeutics Inc Productos terapéuticos de anticuerpos que se unen a CD38
JP6971231B2 (ja) * 2015-11-17 2021-11-24 グローバル・バイオエナジーズ 3−メチルクロトン酸からイソブテンを製造する方法
KR102719065B1 (ko) * 2017-06-08 2024-10-17 블랙 벨트 테라퓨틱스 리미티드 Cd38 조정 항체
KR102771835B1 (ko) * 2017-06-20 2025-02-26 비바솔, 인코포레이티드. Cd38 항체 약물 접합체
CN112313250B (zh) * 2018-06-20 2024-10-01 索伦托药业有限公司 结合cd38的变体抗体

Similar Documents

Publication Publication Date Title
CN110799539B (zh) 抗4-1bb抗体及其制备和使用方法
JP7425604B2 (ja) 抗ctla4-抗pd-1二機能性抗体、その医薬組成物および使用
KR102340832B1 (ko) 항 pd-1 항체 및 그의 용도
TWI821474B (zh) Cd3抗體及其藥物用途
JP6480907B2 (ja) 多量体化技術
TWI804572B (zh) 雙特異性抗體
JP2023099051A (ja) Il2rベータ/共通ガンマ鎖抗体
EP3691663A2 (en) Methods of treating immunotherapy-related toxicity using a gm-csf antagonist
CN107922484A (zh) 结合tim3的抗体治疗剂
JP7688805B2 (ja) 二重特異性抗体
US20230192861A1 (en) Anti-pd-l1/anti-b7-h3 multispecific antibodies and uses thereof
JP2023179541A (ja) Cd3結合分子
JP7574692B2 (ja) 二重特異性抗体
JPWO2020205499A5 (https=)
JPWO2020176549A5 (https=)
JP2025540657A (ja) 抗cd3抗体
RU2021128015A (ru) Антигенсвязывающие белки, которые связываются с bcma
JPWO2020218951A5 (https=)
US20240084026A1 (en) Anti-4-1bb antibodies and methods of making and using thereof
JP7714992B2 (ja) 二重特異性抗体を有効成分として含む医薬組成物
US20250368740A1 (en) Multifunctional recombinant antibody, preparation method and use thereof
CA3125451C (en) Cd137 agonist antibodies and uses thereof