JP2022527084A5 - - Google Patents

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Publication number
JP2022527084A5
JP2022527084A5 JP2021557383A JP2021557383A JP2022527084A5 JP 2022527084 A5 JP2022527084 A5 JP 2022527084A5 JP 2021557383 A JP2021557383 A JP 2021557383A JP 2021557383 A JP2021557383 A JP 2021557383A JP 2022527084 A5 JP2022527084 A5 JP 2022527084A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
heavy chain
light chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021557383A
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English (en)
Japanese (ja)
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JP7555953B2 (ja
JP2022527084A (ja
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Priority claimed from PCT/US2020/025181 external-priority patent/WO2020205499A1/en
Publication of JP2022527084A publication Critical patent/JP2022527084A/ja
Publication of JP2022527084A5 publication Critical patent/JP2022527084A5/ja
Application granted granted Critical
Publication of JP7555953B2 publication Critical patent/JP7555953B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021557383A 2019-03-29 2020-03-27 Cd38に結合する操作されたバリアント抗体 Active JP7555953B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962825983P 2019-03-29 2019-03-29
US62/825,983 2019-03-29
PCT/US2020/025181 WO2020205499A1 (en) 2019-03-29 2020-03-27 Engineered variant antibodies that bind cd38

Publications (3)

Publication Number Publication Date
JP2022527084A JP2022527084A (ja) 2022-05-30
JP2022527084A5 true JP2022527084A5 (https=) 2023-02-16
JP7555953B2 JP7555953B2 (ja) 2024-09-25

Family

ID=72666916

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021557383A Active JP7555953B2 (ja) 2019-03-29 2020-03-27 Cd38に結合する操作されたバリアント抗体

Country Status (6)

Country Link
US (1) US20220144966A1 (https=)
EP (1) EP3947465A4 (https=)
JP (1) JP7555953B2 (https=)
CN (2) CN114524877A (https=)
CA (1) CA3134612A1 (https=)
WO (1) WO2020205499A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3103114A1 (en) * 2018-06-20 2019-12-26 Sorrento Therapeutics, Inc. Variant antibody that binds cd38
CN114516918B (zh) * 2022-03-04 2022-09-27 四川大学华西医院 一种抗体及其应用
CN114409788B (zh) * 2022-03-04 2022-10-04 四川大学华西医院 抗cd38的抗体及其应用
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof
CN120607617A (zh) * 2024-03-07 2025-09-09 宜明昂科生物医药技术(上海)股份有限公司 靶向cd38和cd47的重组融合蛋白

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005049802A2 (en) * 2003-11-14 2005-06-02 Massachusetts Institute Of Technology Anti-hydroxylase antibodies and uses thereof
JP5225069B2 (ja) 2005-03-23 2013-07-03 ゲンマブ エー/エス 多発性骨髄腫の治療のためのcd38に対する抗体
US20090258005A1 (en) * 2007-05-29 2009-10-15 Trubion Pharmaceuticals Inc. Therapeutic compositions and methods
JOP20210044A1 (ar) 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
GB201503812D0 (en) * 2015-03-06 2015-04-22 Univ Aberdeen Antibody molecules and uses thereof
US9951144B2 (en) 2015-04-08 2018-04-24 Sorrento Therapeutics, Inc. Antibody therapeutics that bind CD38
US11124806B2 (en) * 2015-11-17 2021-09-21 Global Bioenergies Methods for producing isobutene from 3-methylcrotonic acid
CN110997722B (zh) * 2017-06-08 2023-09-26 黑带医疗有限公司 Cd38调节抗体
EP3641831B1 (en) 2017-06-20 2024-11-06 Sorrento Therapeutics, Inc. Cd38 antibody drug conjugate
CA3103114A1 (en) * 2018-06-20 2019-12-26 Sorrento Therapeutics, Inc. Variant antibody that binds cd38

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