JPWO2020154275A5 - - Google Patents
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- JPWO2020154275A5 JPWO2020154275A5 JP2021542206A JP2021542206A JPWO2020154275A5 JP WO2020154275 A5 JPWO2020154275 A5 JP WO2020154275A5 JP 2021542206 A JP2021542206 A JP 2021542206A JP 2021542206 A JP2021542206 A JP 2021542206A JP WO2020154275 A5 JPWO2020154275 A5 JP WO2020154275A5
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- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- trp
- phe
- Prior art date
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025071352A JP2025114614A (ja) | 2019-01-22 | 2025-04-23 | Ｇ１２ｒ変異を有するｒａｓに対するｈｌａクラスｉｉ拘束性ｔ細胞受容体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962795203P | 2019-01-22 | 2019-01-22 | |
| US62/795,203 | 2019-01-22 | ||
| PCT/US2020/014382 WO2020154275A1 (en) | 2019-01-22 | 2020-01-21 | Hla class ii-restricted t cell receptors against ras with g12r mutation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025071352A Division JP2025114614A (ja) | 2019-01-22 | 2025-04-23 | Ｇ１２ｒ変異を有するｒａｓに対するｈｌａクラスｉｉ拘束性ｔ細胞受容体 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022523024A JP2022523024A (ja) | 2022-04-21 |
| JPWO2020154275A5 true JPWO2020154275A5 (https=) | 2023-01-31 |
| JP2022523024A5 JP2022523024A5 (https=) | 2023-01-31 |
| JP7672979B2 JP7672979B2 (ja) | 2025-05-08 |
Family
ID=69591774
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021542206A Active JP7672979B2 (ja) | 2019-01-22 | 2020-01-21 | Ｇ１２ｒ変異を有するｒａｓに対するｈｌａクラスｉｉ拘束性ｔ細胞受容体 |
| JP2025071352A Pending JP2025114614A (ja) | 2019-01-22 | 2025-04-23 | Ｇ１２ｒ変異を有するｒａｓに対するｈｌａクラスｉｉ拘束性ｔ細胞受容体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025071352A Pending JP2025114614A (ja) | 2019-01-22 | 2025-04-23 | Ｇ１２ｒ変異を有するｒａｓに対するｈｌａクラスｉｉ拘束性ｔ細胞受容体 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US12448428B2 (https=) |
| EP (1) | EP3914612A1 (https=) |
| JP (2) | JP7672979B2 (https=) |
| KR (1) | KR102934104B1 (https=) |
| CN (2) | CN113412277B (https=) |
| AU (1) | AU2020211922B2 (https=) |
| CA (1) | CA3127096A1 (https=) |
| WO (1) | WO2020154275A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL305393A (en) | 2021-02-25 | 2023-10-01 | Alaunos Therapeutics Inc | Recombinant vectors comprising polycistronic expression cassettes and methods of use thereof |
| US20250145950A1 (en) | 2022-02-01 | 2025-05-08 | Alaunos Therapeutics, Inc. | Methods for Activation and Expansion of T Cells |
| WO2025006196A1 (en) | 2023-06-28 | 2025-01-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | T cell receptors targeting ras with g12d, g12r, or g12v mutation |
| CN119119290B (zh) * | 2024-07-15 | 2025-11-25 | 上海交通大学医学院附属瑞金医院 | 靶向flt3 d835h突变衍生新抗原的tcr及应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003265948B8 (en) | 2002-09-06 | 2009-09-03 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Immunotherapy with in vitro-selected antigen-specific lymphocytes after nonmyeloablative lymphodepleting chemotherapy |
| US8383099B2 (en) | 2009-08-28 | 2013-02-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Adoptive cell therapy with young T cells |
| WO2012129201A1 (en) | 2011-03-22 | 2012-09-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of growing tumor infiltrating lymphocytes in gas-permeable containers |
| ES2834070T3 (es) | 2011-09-15 | 2021-06-16 | Us Health | Receptores de células T que reconocen MAGE restringido por HLA-A1 o HLA-Cw7 |
| WO2015123532A1 (en) * | 2014-02-16 | 2015-08-20 | Globeimmune, Inc. | Ras g12r immunotherapy for ras mutation-positive cancers |
| MX384919B (es) * | 2014-11-26 | 2025-03-14 | Us Health | Receptores de células t de kras anti-mutado. |
| RU2018101225A (ru) | 2015-06-16 | 2019-07-16 | Тарговакс Аса | Мутированные фрагменты белка ras |
| JP7185524B2 (ja) * | 2015-09-15 | 2022-12-07 | アメリカ合衆国 | Ｈｌａ－ｃｗ８拘束性の変異ｋｒａｓを認識するｔ細胞受容体 |
| DE102016115246C5 (de) * | 2016-08-17 | 2018-12-20 | Immatics Biotechnologies Gmbh | Neue t-zellrezeptoren und deren verwendung in immuntherapie |
| CN108264550B (zh) * | 2017-01-04 | 2021-04-23 | 香雪生命科学技术（广东）有限公司 | 一种识别源自于prame抗原短肽的tcr |
| CN108395479B (zh) * | 2017-02-06 | 2021-07-16 | 高军 | 一种有关kras基因突变的t细胞受体 |
| WO2025006196A1 (en) | 2023-06-28 | 2025-01-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | T cell receptors targeting ras with g12d, g12r, or g12v mutation |
-
2020
- 2020-01-21 CN CN202080010373.0A patent/CN113412277B/zh active Active
- 2020-01-21 AU AU2020211922A patent/AU2020211922B2/en active Active
- 2020-01-21 CN CN202510854434.6A patent/CN120607607A/zh active Pending
- 2020-01-21 US US17/424,591 patent/US12448428B2/en active Active
- 2020-01-21 EP EP20705599.7A patent/EP3914612A1/en active Pending
- 2020-01-21 KR KR1020217026169A patent/KR102934104B1/ko active Active
- 2020-01-21 JP JP2021542206A patent/JP7672979B2/ja active Active
- 2020-01-21 CA CA3127096A patent/CA3127096A1/en active Pending
- 2020-01-21 WO PCT/US2020/014382 patent/WO2020154275A1/en not_active Ceased
-
2025
- 2025-04-23 JP JP2025071352A patent/JP2025114614A/ja active Pending
- 2025-09-19 US US19/334,152 patent/US20260008832A1/en active Pending
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