JPWO2020132059A5 - - Google Patents
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- Publication number
- JPWO2020132059A5 JPWO2020132059A5 JP2021535829A JP2021535829A JPWO2020132059A5 JP WO2020132059 A5 JPWO2020132059 A5 JP WO2020132059A5 JP 2021535829 A JP2021535829 A JP 2021535829A JP 2021535829 A JP2021535829 A JP 2021535829A JP WO2020132059 A5 JPWO2020132059 A5 JP WO2020132059A5
- Authority
- JP
- Japan
- Prior art keywords
- promoter
- gene
- derepressible
- mammalian cell
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025039219A JP2025102801A (ja) | 2018-12-21 | 2025-03-12 | アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862783589P | 2018-12-21 | 2018-12-21 | |
| US62/783,589 | 2018-12-21 | ||
| US201962866092P | 2019-06-25 | 2019-06-25 | |
| US62/866,092 | 2019-06-25 | ||
| PCT/US2019/067156 WO2020132059A1 (en) | 2018-12-21 | 2019-12-18 | Adeno-associated virus (aav) producer cell line and related methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025039219A Division JP2025102801A (ja) | 2018-12-21 | 2025-03-12 | アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022516004A JP2022516004A (ja) | 2022-02-24 |
| JPWO2020132059A5 true JPWO2020132059A5 (https=) | 2022-12-26 |
| JP2022516004A5 JP2022516004A5 (https=) | 2022-12-26 |
| JP7650800B2 JP7650800B2 (ja) | 2025-03-25 |
Family
ID=71099162
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021535829A Active JP7650800B2 (ja) | 2018-12-21 | 2019-12-18 | アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法 |
| JP2025039219A Pending JP2025102801A (ja) | 2018-12-21 | 2025-03-12 | アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025039219A Pending JP2025102801A (ja) | 2018-12-21 | 2025-03-12 | アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11739347B2 (https=) |
| EP (1) | EP3891290A4 (https=) |
| JP (2) | JP7650800B2 (https=) |
| KR (1) | KR20210108423A (https=) |
| CN (1) | CN113396222A (https=) |
| IL (1) | IL284219A (https=) |
| SG (1) | SG11202106217TA (https=) |
| WO (1) | WO2020132059A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4189077A1 (en) * | 2020-07-30 | 2023-06-07 | Shape Therapeutics Inc. | Stable cell lines for inducible production of raav virions |
| EP4229205B1 (en) * | 2020-10-15 | 2025-05-14 | F. Hoffmann-La Roche AG | Nucleic acid constructs for va rna transcription |
| CN112501209B (zh) * | 2020-12-07 | 2024-02-13 | 和元生物技术（上海）股份有限公司 | 外源基因可控表达的腺相关病毒包装方法 |
| CN116829725A (zh) * | 2021-02-12 | 2023-09-29 | 富士胶片株式会社 | 用于产生腺相关病毒的试剂盒及其利用 |
| EP4322975A4 (en) * | 2021-04-14 | 2025-03-26 | Capsida, Inc. | PLASMIDS AND PROCESSES FOR PRODUCING ADENO-ASSOCIATED VIRUSES |
| EP4410971A4 (en) * | 2021-09-30 | 2025-06-04 | FUJIFILM Corporation | METHOD FOR PRODUCING AN ADENO-ASSOCIATED VIRUS, CELLS AND EXPRESSION VECTOR |
| AU2022373653A1 (en) * | 2021-10-18 | 2024-05-02 | Regeneron Pharmaceuticals, Inc. | Eukaryotic cells comprising adenovirus-associated virus polynucleotides |
| EP4473123A4 (en) * | 2022-02-01 | 2026-03-11 | Shape Therapeutics Inc | STABLE CELL LINES FOR INDUCIBLE VAAR VIRION PRODUCTION |
| EP4491717A4 (en) | 2022-03-08 | 2025-11-12 | Fujifilm Corp | PRODUCING CELL, PRODUCTION METHOD FOR PRODUCING PRODUCING CELLS AND PRODUCTION METHOD FOR ADENE-ASSOCIATED VIRUS |
| CN120092093A (zh) * | 2022-08-25 | 2025-06-03 | 富士胶片株式会社 | 靶病毒的制造方法及培养组合物 |
| EP4624584A1 (en) * | 2022-12-27 | 2025-10-01 | Synplogen Co., Ltd. | Helper gene control |
| US12410436B2 (en) * | 2023-10-31 | 2025-09-09 | Lonza Houston, Inc. | Adeno-associated virus (AAV) producer cell lines |
| WO2025122676A1 (en) * | 2023-12-05 | 2025-06-12 | Shape Therapeutics Inc. | Systems and methods for raav production using a biphasic culture |
| WO2025168663A1 (en) | 2024-02-09 | 2025-08-14 | F. Hoffmann-La Roche Ag | Method for producing recombinant adeno-associated viral particles |
| WO2025252480A1 (en) | 2024-06-07 | 2025-12-11 | F. Hoffmann-La Roche Ag | Method for purifying plasmid dna |
| CN118460545B (zh) * | 2024-07-08 | 2025-02-11 | 凌意(杭州)生物科技有限公司 | 一种诱导型表达Rep多肽的表达框 |
| US20260022401A1 (en) | 2024-07-22 | 2026-01-22 | Hoffmann-La Roche Inc. | Novel AAV rep ORFs and Rep polypeptides |
| WO2026037757A1 (en) | 2024-08-13 | 2026-02-19 | F. Hoffmann-La Roche Ag | Modified aav particles |
| WO2026044087A1 (en) * | 2024-08-21 | 2026-02-26 | Shape Therapeutics Inc. | Increased cellular stability for aav production |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5622856A (en) | 1995-08-03 | 1997-04-22 | Avigen | High efficiency helper system for AAV vector production |
| US6037177A (en) * | 1997-08-08 | 2000-03-14 | Cell Genesys, Inc. | Method for increasing the efficiency of recombinant AAV production |
| JP2002153278A (ja) * | 2000-11-22 | 2002-05-28 | Hisamitsu Pharmaceut Co Inc | ウイルスベクターの製造に用いられる細胞、その製法およびその細胞を用いたウイルスベクターの製造方法 |
| AU2002305778A1 (en) * | 2001-05-31 | 2002-12-09 | The Rockefeller University | Method for generating replication defective viral vectors that are helper free |
| AU2002367943A1 (en) * | 2001-12-18 | 2003-12-22 | University Of North Carolina At Chapel Hill | Improved reagents and methods for producing parvoviruses |
| EP1844148A2 (en) | 2005-01-31 | 2007-10-17 | University of Iowa Research Foundation | Nucleic acid silencing of huntington's disease gene |
| US20130023033A1 (en) * | 2010-03-29 | 2013-01-24 | The Trustees Of The University Of Pennsylvania | Pharmacologically induced transgene ablation system |
| JP6661544B2 (ja) | 2014-04-24 | 2020-03-11 | ミルテニイ バイオテック ゲゼルシャフト ミット ベシュレンクテル ハフツング | 遺伝子改変したｔ細胞の自動生成法 |
| JP2018508223A (ja) * | 2015-03-16 | 2018-03-29 | ボード・オブ・トラスティーズ、サザン・イリノイ・ユニバーシティ | 安定な遺伝子発現のための系 |
| WO2018136566A1 (en) | 2017-01-18 | 2018-07-26 | F1 Oncology, Inc. | Methods of transducing and expanding immune cells and uses thereof |
| US10858631B2 (en) * | 2017-04-18 | 2020-12-08 | Glaxosmithkline Intellectual Property Development Limited | Methods for adeno-associated viral vector production |
-
2019
- 2019-12-18 SG SG11202106217TA patent/SG11202106217TA/en unknown
- 2019-12-18 JP JP2021535829A patent/JP7650800B2/ja active Active
- 2019-12-18 KR KR1020217022728A patent/KR20210108423A/ko active Pending
- 2019-12-18 CN CN201980090045.3A patent/CN113396222A/zh active Pending
- 2019-12-18 EP EP19899841.1A patent/EP3891290A4/en active Pending
- 2019-12-18 US US16/719,251 patent/US11739347B2/en active Active
- 2019-12-18 WO PCT/US2019/067156 patent/WO2020132059A1/en not_active Ceased
-
2021
- 2021-06-20 IL IL284219A patent/IL284219A/en unknown
-
2023
- 2023-07-14 US US18/352,657 patent/US12529074B2/en active Active
-
2025
- 2025-03-12 JP JP2025039219A patent/JP2025102801A/ja active Pending
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