JPWO2020109864A5 - - Google Patents
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- Publication number
- JPWO2020109864A5 JPWO2020109864A5 JP2021530885A JP2021530885A JPWO2020109864A5 JP WO2020109864 A5 JPWO2020109864 A5 JP WO2020109864A5 JP 2021530885 A JP2021530885 A JP 2021530885A JP 2021530885 A JP2021530885 A JP 2021530885A JP WO2020109864 A5 JPWO2020109864 A5 JP WO2020109864A5
- Authority
- JP
- Japan
- Prior art keywords
- isolated
- peptide
- seq
- dpep
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 36
- 101000932212 Mus musculus Dipeptidase 1 Proteins 0.000 claims description 20
- 150000001413 amino acids Chemical class 0.000 claims description 16
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 12
- 206010063837 Reperfusion injury Diseases 0.000 claims description 8
- 208000035475 disorder Diseases 0.000 claims description 8
- 208000012947 ischemia reperfusion injury Diseases 0.000 claims description 8
- 230000021736 acetylation Effects 0.000 claims description 6
- 238000006640 acetylation reaction Methods 0.000 claims description 6
- 230000004048 modification Effects 0.000 claims description 5
- 238000012986 modification Methods 0.000 claims description 5
- 208000009304 Acute Kidney Injury Diseases 0.000 claims description 4
- 150000008574 D-amino acids Chemical class 0.000 claims description 4
- 206010061218 Inflammation Diseases 0.000 claims description 4
- 206010027476 Metastases Diseases 0.000 claims description 4
- 206010028980 Neoplasm Diseases 0.000 claims description 4
- 208000033626 Renal failure acute Diseases 0.000 claims description 4
- 206010040047 Sepsis Diseases 0.000 claims description 4
- 208000027418 Wounds and injury Diseases 0.000 claims description 4
- 201000011040 acute kidney failure Diseases 0.000 claims description 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 4
- 230000009435 amidation Effects 0.000 claims description 4
- 238000007112 amidation reaction Methods 0.000 claims description 4
- 230000006378 damage Effects 0.000 claims description 4
- 201000010099 disease Diseases 0.000 claims description 4
- 239000003937 drug carrier Substances 0.000 claims description 4
- 230000004054 inflammatory process Effects 0.000 claims description 4
- 208000014674 injury Diseases 0.000 claims description 4
- 230000009401 metastasis Effects 0.000 claims description 4
- 230000011987 methylation Effects 0.000 claims description 4
- 238000007069 methylation reaction Methods 0.000 claims description 4
- 210000000056 organ Anatomy 0.000 claims description 4
- 239000008194 pharmaceutical composition Substances 0.000 claims description 4
- 238000002054 transplantation Methods 0.000 claims description 4
- 125000000539 amino acid group Chemical group 0.000 claims description 2
- 230000006287 biotinylation Effects 0.000 claims description 2
- 238000007413 biotinylation Methods 0.000 claims description 2
- 125000003636 chemical group Chemical group 0.000 claims description 2
- 230000013595 glycosylation Effects 0.000 claims description 2
- 238000006206 glycosylation reaction Methods 0.000 claims description 2
- 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 claims description 2
- 230000006320 pegylation Effects 0.000 claims description 2
- 230000013823 prenylation Effects 0.000 claims description 2
- 238000007363 ring formation reaction Methods 0.000 claims description 2
- 238000006467 substitution reaction Methods 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 8
- 238000000034 method Methods 0.000 description 8
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024007364A JP2024028553A (ja) | 2018-11-30 | 2024-01-22 | Ｄｐｅｐ－１結合剤および使用の方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862773733P | 2018-11-30 | 2018-11-30 | |
| US62/773,733 | 2018-11-30 | ||
| PCT/IB2019/001289 WO2020109864A1 (en) | 2018-11-30 | 2019-12-02 | Dpep-1 binding agents and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024007364A Division JP2024028553A (ja) | 2018-11-30 | 2024-01-22 | Ｄｐｅｐ－１結合剤および使用の方法 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022509258A JP2022509258A (ja) | 2022-01-20 |
| JPWO2020109864A5 true JPWO2020109864A5 (https=) | 2022-10-05 |
| JP2022509258A5 JP2022509258A5 (https=) | 2022-10-05 |
| JP7535514B2 JP7535514B2 (ja) | 2024-08-16 |
Family
ID=70853301
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021530885A Active JP7535514B2 (ja) | 2018-11-30 | 2019-12-02 | Ｄｐｅｐ－１結合剤および使用の方法 |
| JP2024007364A Pending JP2024028553A (ja) | 2018-11-30 | 2024-01-22 | Ｄｐｅｐ－１結合剤および使用の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024007364A Pending JP2024028553A (ja) | 2018-11-30 | 2024-01-22 | Ｄｐｅｐ－１結合剤および使用の方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US11286278B2 (https=) |
| EP (1) | EP3887390A4 (https=) |
| JP (2) | JP7535514B2 (https=) |
| AU (1) | AU2019386379B2 (https=) |
| CA (1) | CA3121300A1 (https=) |
| IL (1) | IL283231B1 (https=) |
| WO (1) | WO2020109864A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7535514B2 (ja) * | 2018-11-30 | 2024-08-16 | アーチ バイオパートナーズ， インコーポレイテッド | Ｄｐｅｐ－１結合剤および使用の方法 |
| EP4320167A4 (en) * | 2021-04-08 | 2025-08-06 | Nat Res Council Canada | DPEP-1 BINDING AGENTS AND METHODS OF USE THEREOF |
| EP4574146A1 (en) | 2023-12-18 | 2025-06-25 | Telara Pharma S.L. | Dhp-i inhibitors for use as neuroprotectants and in the treatment of neuroinflammatory diseases |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7223558B2 (en) * | 2001-07-11 | 2007-05-29 | Bristol-Myers Squibb Company | Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunologobulin folds, BGS2, 3, and 4 and variants thereof |
| WO2007081751A2 (en) * | 2006-01-05 | 2007-07-19 | The Johns Hopkins University | Compositions and methods for the treatment of cancer |
| EP2561359A1 (en) * | 2010-04-20 | 2013-02-27 | Addex Pharma SA | Chimeric polypeptides useful in proximal and dynamic high-throughput screening methods |
| WO2012112420A1 (en) * | 2011-02-14 | 2012-08-23 | Allergan, Inc. | Treatments using psma ligand endopeptidases |
| WO2015120536A1 (en) * | 2014-02-13 | 2015-08-20 | Arch Cancer Therapeutics, Inc. | Peptides that block leukocyte recruitment and methods of use |
| ES3057215T3 (en) * | 2015-08-11 | 2026-02-26 | Arch Biopartners Inc | Antagonist binding to dpep-1 for use in treating or preventing acute kidney injury or ischemia-reperfusion injury |
| EP3519443A4 (en) * | 2016-09-30 | 2020-06-10 | Baylor College of Medicine | CHIMERIC ANTIGEN RECEPTOR THERAPY WITH REDUCED CYTOTOXICITY FOR VIRAL DISEASE |
| JP2019529499A (ja) * | 2016-09-30 | 2019-10-17 | ベイラー カレッジ オブ メディスンＢａｙｌｏｒ Ｃｏｌｌｅｇｅ Ｏｆ Ｍｅｄｉｃｉｎｅ | 組織指向性発現を用いた抗体ベースの遺伝子治療 |
| JP7535514B2 (ja) * | 2018-11-30 | 2024-08-16 | アーチ バイオパートナーズ， インコーポレイテッド | Ｄｐｅｐ－１結合剤および使用の方法 |
-
2019
- 2019-12-02 JP JP2021530885A patent/JP7535514B2/ja active Active
- 2019-12-02 EP EP19891278.4A patent/EP3887390A4/en active Pending
- 2019-12-02 US US16/700,901 patent/US11286278B2/en active Active
- 2019-12-02 WO PCT/IB2019/001289 patent/WO2020109864A1/en not_active Ceased
- 2019-12-02 CA CA3121300A patent/CA3121300A1/en active Pending
- 2019-12-02 AU AU2019386379A patent/AU2019386379B2/en active Active
-
2021
- 2021-05-18 IL IL283231A patent/IL283231B1/en unknown
-
2022
- 2022-02-14 US US17/670,998 patent/US20220251140A1/en not_active Abandoned
-
2024
- 2024-01-22 JP JP2024007364A patent/JP2024028553A/ja active Pending
-
2025
- 2025-07-07 US US19/261,807 patent/US20250333443A1/en active Pending
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