JPWO2020097369A5 - - Google Patents
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- Publication number
- JPWO2020097369A5 JPWO2020097369A5 JP2021524058A JP2021524058A JPWO2020097369A5 JP WO2020097369 A5 JPWO2020097369 A5 JP WO2020097369A5 JP 2021524058 A JP2021524058 A JP 2021524058A JP 2021524058 A JP2021524058 A JP 2021524058A JP WO2020097369 A5 JPWO2020097369 A5 JP WO2020097369A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- primate
- cell differentiation
- hair cell
- hair
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862756910P | 2018-11-07 | 2018-11-07 | |
| US62/756,910 | 2018-11-07 | ||
| US201962888105P | 2019-08-16 | 2019-08-16 | |
| US62/888,105 | 2019-08-16 | ||
| PCT/US2019/060324 WO2020097369A1 (en) | 2018-11-07 | 2019-11-07 | Compositions and methods of inducing differentiation of a hair cell |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022512921A JP2022512921A (ja) | 2022-02-07 |
| JP2022512921A5 JP2022512921A5 (https=) | 2022-12-28 |
| JPWO2020097369A5 true JPWO2020097369A5 (https=) | 2022-12-28 |
Family
ID=70611182
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021524058A Pending JP2022512921A (ja) | 2018-11-07 | 2019-11-07 | 有毛細胞の分化を誘導する組成物及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220395582A1 (https=) |
| EP (1) | EP3880827A4 (https=) |
| JP (1) | JP2022512921A (https=) |
| CN (1) | CN113874512A (https=) |
| AU (1) | AU2019376084A1 (https=) |
| CA (1) | CA3119059A1 (https=) |
| WO (1) | WO2020097369A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020160371A1 (en) | 2019-02-01 | 2020-08-06 | The University Of Hong Kong | Innervated organoid compositions and methods of making same |
| WO2020243613A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| WO2020243633A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| KR20230061333A (ko) * | 2020-06-23 | 2023-05-08 | 칠드런즈 호스피탈 메디칼 센터 | 인슐린 저항성 모델 |
| JP2024517843A (ja) * | 2021-05-05 | 2024-04-23 | デシベル セラピューティクス インコーポレイテッド | ステレオシリン二重ベクター系を使用して感音性難聴を治療するための組成物及び方法 |
| JP2025503508A (ja) * | 2021-12-23 | 2025-02-04 | ユニバーシティ オブ ロチェスター | 内耳への薬剤の送達のための組成物及び方法 |
| WO2025094056A1 (en) * | 2023-10-31 | 2025-05-08 | Children's Medical Research Institute | Gene therapy constructs and methods of use therefor |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100419079C (zh) * | 1998-07-14 | 2008-09-17 | 科里克萨有限公司 | 用于治疗和诊断前列腺癌的组合物和方法 |
| US20040166091A1 (en) * | 2003-02-24 | 2004-08-26 | Genvec, Inc. | Materials and methods for treating disorders of the ear |
| US20050281786A1 (en) * | 2004-06-18 | 2005-12-22 | David Poulsen | AAV mediated gene delivery to cochlear cells |
| CA2801535C (en) * | 2010-06-04 | 2017-05-30 | Hough Ear Institute | Composition and method for inner ear sensory hair cell regeneration or replacement |
| KR20140047141A (ko) * | 2011-08-03 | 2014-04-21 | 쿠아크 파마수티칼스 인코퍼레이티드 | 청력 및 균형 장애를 치료하기 위한 이중-가닥 올리고뉴클레오티드 화합물들 |
| CA2909733C (en) * | 2013-04-18 | 2023-10-17 | Fondazione Telethon | Effective delivery of large genes by dual aav vectors |
| JP2015534818A (ja) * | 2013-11-04 | 2015-12-07 | ジェネシス リサーチ インスティチュート | 聴覚を治療するための組成物および方法 |
| SG11201804814YA (en) * | 2015-12-11 | 2018-07-30 | Massachusetts Eye & Ear Infirmary | Materials and methods for delivering nucleic acids to cochlear and vestibular cells |
| WO2017108931A1 (en) * | 2015-12-22 | 2017-06-29 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Improved hybrid dual recombinant aav vector systems for gene therapy |
| WO2017136764A1 (en) * | 2016-02-05 | 2017-08-10 | The General Hospital Corporation | Hybrid system for efficient gene delivery to cells of the inner ear |
| US20190142969A1 (en) * | 2016-04-26 | 2019-05-16 | Massachusetts Eye And Ear Infirmary | ISL1-Based Gene Therapy to Treat Hearing Loss |
| JP2019530737A (ja) * | 2016-08-23 | 2019-10-24 | アコーオス インコーポレイテッド | ヒト対象において非加齢性聴力障害を治療するための組成物および方法 |
| CA3115810A1 (en) * | 2018-10-11 | 2020-04-16 | Decibel Therapeutics, Inc. | Aav1 vectors and uses thereof for treatment of otic indications |
| CN110437317B (zh) * | 2019-01-30 | 2023-05-02 | 上海科技大学 | 具有变异衣壳蛋白的腺相关病毒及其用途 |
-
2019
- 2019-11-07 CA CA3119059A patent/CA3119059A1/en active Pending
- 2019-11-07 EP EP19882633.1A patent/EP3880827A4/en not_active Withdrawn
- 2019-11-07 JP JP2021524058A patent/JP2022512921A/ja active Pending
- 2019-11-07 US US17/291,906 patent/US20220395582A1/en not_active Abandoned
- 2019-11-07 CN CN201980087541.3A patent/CN113874512A/zh active Pending
- 2019-11-07 AU AU2019376084A patent/AU2019376084A1/en not_active Abandoned
- 2019-11-07 WO PCT/US2019/060324 patent/WO2020097369A1/en not_active Ceased
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